Alf Hamann

Alf Hamann

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Alf Hamann

Alf Hamann

Publications by authors named "Alf Hamann"

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Linear polysialoside outperforms dendritic analogs for inhibition of influenza virus infection in vitro and in vivo.

Biomaterials 2017 Sep 20;138:22-34. Epub 2017 May 20.

Institut für Chemie und Biochemie Organische Chemie, Freie Universität Berlin, Takustr. 3, 14195 Berlin, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.biomaterials.2017.05.028DOI Listing
September 2017

Multivalent Peptide-Nanoparticle Conjugates for Influenza-Virus Inhibition.

Angew Chem Int Ed Engl 2017 05 26;56(21):5931-5936. Epub 2017 Apr 26.

Institut für Biologie, Molekulare Biophysik, IRI Life Sciences, Humboldt-Universität zu Berlin, Invalidenstrasse 42, 10115, Berlin, Germany.

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http://dx.doi.org/10.1002/anie.201702005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5485077PMC
May 2017

Facilitated Peptide Transport the Mucosal Epithelium: Impact on Tolerance Induction.

Front Immunol 2017 6;8:216. Epub 2017 Mar 6.

Experimental Rheumatology, Deutsches Rheuma-Forschungszentrum, Berlin, Germany; Experimental Rheumatology, Department of Rheumatology and Clinical Immunology, Charité Universitätsmedizin Berlin, Berlin, Germany.

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http://dx.doi.org/10.3389/fimmu.2017.00216DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5337492PMC
March 2017

Immune Modulation and Prevention of Autoimmune Disease by Repeated Sequences from Parasites Linked to Self Antigens.

J Neuroimmune Pharmacol 2016 12 12;11(4):749-762. Epub 2016 Aug 12.

Max-Delbrück-Center for Molecular Medicine (MDC), Berlin, Germany.

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http://dx.doi.org/10.1007/s11481-016-9701-xDOI Listing
December 2016

Core 2 ß1,6-N-acetylglucosaminyltransferase-I, crucial for P-selectin ligand expression is controlled by a distal enhancer regulated by STAT4 and T-bet in CD4+ T helper cells 1.

Mol Immunol 2016 09 6;77:132-40. Epub 2016 Aug 6.

Deutsches Rheumaforschungszentrum, Experimentelle Rheumatologie, Berlin, Germany; Charité Universitätsmedizin Berlin, Medizinische Klinik für Gastroenterologie, Infektiologie und Rheumatologie, Hindenburgdamm 30, 12200 Berlin, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.molimm.2016.08.001DOI Listing
September 2016

reChIP-seq reveals widespread bivalency of H3K4me3 and H3K27me3 in CD4(+) memory T cells.

Nat Commun 2016 08 17;7:12514. Epub 2016 Aug 17.

Otto-Warburg-Laboratory: Epigenomics, Max Planck Institute for Molecular Genetics, Ihnestrasse 63-73, 14195 Berlin, Germany.

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http://dx.doi.org/10.1038/ncomms12514DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4992058PMC
August 2016

Anti-Inflammatory Effects of IL-27 in Zymosan-Induced Peritonitis: Inhibition of Neutrophil Recruitment Partially Explained by Impaired Mobilization from Bone Marrow and Reduced Chemokine Levels.

PLoS One 2015 11;10(9):e0137651. Epub 2015 Sep 11.

Department of Experimental Rheumatology, Deutsches Rheuma-Forschungszentrum, Berlin, Germany; Department of Rheumatology and Clinical Immunology, Charité-Universitätsmedizin Berlin, Berlin, Germany.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0137651PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4567321PMC
May 2016

Surface-modified yeast cells: A novel eukaryotic carrier for oral application.

J Control Release 2016 Feb 5;224:1-7. Epub 2016 Jan 5.

Molecular and Cell Biology, Saarland University, D-66123 Saarbrücken, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.jconrel.2015.12.054DOI Listing
February 2016

Integrin αE(CD103) Is Involved in Regulatory T-Cell Function in Allergic Contact Hypersensitivity.

J Invest Dermatol 2015 Dec 23;135(12):2982-2991. Epub 2015 Jul 23.

Department of Dermatology, Venereology, and Allergology, Georg August University, Göttingen, Germany; Lower Saxony Institute of Occupational Dermatology, University Medical Center Göttingen and University of Osnabrück, Osnabrück, Germany. Electronic address:

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http://dx.doi.org/10.1038/jid.2015.287DOI Listing
December 2015

Tolerogenic modulation of the immune response by oligoglycerol- and polyglycerol-peptide conjugates.

Bioconjug Chem 2015 Apr 2;26(4):669-79. Epub 2015 Apr 2.

†Organic and Macromolecular Chemistry, Department of Chemistry and Biochemistry, Free University Berlin, Takustrasse 3, 14195 Berlin, Germany.

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http://dx.doi.org/10.1021/bc500608fDOI Listing
April 2015

Identification of two regulatory elements controlling Fucosyltransferase 7 transcription in murine CD4+ T cells.

Mol Immunol 2014 Nov 7;62(1):1-9. Epub 2014 Jun 7.

Charité, Universitätsmedizin Berlin, Experimentelle Rheumatologie c/o. Deutsches Rheuma-Forschungszentrum, Charitèplatz 1, 10117 Berlin, Germany; Charité, Universitätsmedizin Berlin, Medizinische Klinik für Gastroenterologie, Infektiologie und Rheumatologie, Hindenburgdamm 30, 12200 Berlin, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.molimm.2014.05.005DOI Listing
November 2014

NK cells gain higher IFN-γ competence during terminal differentiation.

Eur J Immunol 2014 Jul 19;44(7):2074-84. Epub 2014 May 19.

Innate Immunity, Deutsches Rheuma-Forschungszentrum, A Leibniz Institute, Berlin, Germany.

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http://dx.doi.org/10.1002/eji.201344072DOI Listing
July 2014

Influence of CD8 T cell priming in liver and gut on the enterohepatic circulation.

J Hepatol 2014 Jun 19;60(6):1143-50. Epub 2014 Feb 19.

Dept. of Hepatology and Gastroenterology, Charité Universitätsmedizin, CVK, Berlin, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.jhep.2014.02.011DOI Listing
June 2014

CD8 T cells primed in the gut-associated lymphoid tissue induce immune-mediated cholangitis in mice.

Hepatology 2014 Feb 18;59(2):601-11. Epub 2013 Dec 18.

Department of Hepatology and Gastroenterology, Charité Universitätsmedizin, CVK, Berlin, Germany.

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http://dx.doi.org/10.1002/hep.26702DOI Listing
February 2014

Connecting liver and gut: murine liver sinusoidal endothelium induces gut tropism of CD4+ T cells via retinoic acid.

Hepatology 2012 Jun 18;55(6):1976-84. Epub 2012 Mar 18.

Medical Clinic I,Charité Universitätsmedizin Berlin, Berlin, Germany.

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http://dx.doi.org/10.1002/hep.24816DOI Listing
June 2012

Regulatory T cells stay on course.

Authors:
Alf Hamann

Immunity 2012 Feb;36(2):161-3

Experimental Rheumatology, Charité Universitätsmedizin Berlin and Deutsches Rheuma-Forschungszentrum Berlin, 10117 Berlin, Germany.

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http://dx.doi.org/10.1016/j.immuni.2012.02.004DOI Listing
February 2012

Accumulation and local proliferation of antigen-specific CD4+ T cells in antigen-bearing tissue.

Immunol Cell Biol 2011 May 9;89(4):566-72. Epub 2010 Nov 9.

Experimentelle Rheumatologie c/o Deutsches Rheumaforschungszentrum, Charité-Universitaetsmedizin, Berlin, Germany.

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http://dx.doi.org/10.1038/icb.2010.128DOI Listing
May 2011

Epigenetic modification of the human CCR6 gene is associated with stable CCR6 expression in T cells.

Blood 2011 Mar 12;117(10):2839-46. Epub 2011 Jan 12.

Charité University Medicine Berlin, Research Centre for ImmunoSciences, Germany.

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http://dx.doi.org/10.1182/blood-2010-06-293027DOI Listing
March 2011

Selective depletion of Foxp3+ regulatory T cells improves effective therapeutic vaccination against established melanoma.

Cancer Res 2010 Oct 5;70(20):7788-99. Epub 2010 Oct 5.

Experimental Immunology, Helmholtz Centre for Infection Research, Braunschweig, Germany.

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http://dx.doi.org/10.1158/0008-5472.CAN-10-1736DOI Listing
October 2010

CD30 discriminates heat shock protein 60-induced FOXP3+ CD4+ T cells with a regulatory phenotype.

J Immunol 2010 Aug 14;185(4):2071-9. Epub 2010 Jul 14.

Center for Molecular and Cellular Immunology, University Medical Center Utrecht, The Netherlands.

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http://www.jimmunol.org/cgi/doi/10.4049/jimmunol.0901901
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http://dx.doi.org/10.4049/jimmunol.0901901DOI Listing
August 2010

How T cells find their way around.

Authors:
Alf Hamann

Methods Mol Biol 2010 ;616:3-13

Experimentelle Rheumatologie, CC12, Charité Universitätsmedizin Berlin, Berlin, Germany.

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http://dx.doi.org/10.1007/978-1-60761-461-6_1DOI Listing
June 2010

Memory T-cell trafficking: new directions for busy commuters.

Immunology 2010 Jun 12;130(2):158-65. Epub 2010 Apr 12.

Section of Immunobiology, Division of Infection and Immunity, Department of Medicine, Imperial College London, Hammersmith Hospital Campus, Du Cane Road, London, UK.

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http://dx.doi.org/10.1111/j.1365-2567.2010.03278.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2878460PMC
June 2010

In-vitro-induced Th17 cells fail to induce inflammation in vivo and show an impaired migration into inflamed sites.

Eur J Immunol 2010 Apr;40(4):1089-98

Deutsches Rheumaforschungszentrum Berlin, Berlin, Germany.

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http://dx.doi.org/10.1002/eji.200939487DOI Listing
April 2010

T cells as pioneers: antigen-specific T cells condition inflamed sites for high-rate antigen-non-specific effector cell recruitment.

Immunology 2009 Sep 26;128(1 Suppl):e870-80. Epub 2009 Mar 26.

Experimentelle Rheumatologie, Charité-Universitaetsmedizin c/o Deutsches Rheuma-forschungszentrum, Berlin, Germany.

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http://doi.wiley.com/10.1111/j.1365-2567.2009.03096.x
Publisher Site
http://dx.doi.org/10.1111/j.1365-2567.2009.03096.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2753954PMC
September 2009

CD152 (CTLA-4) determines CD4 T cell migration in vitro and in vivo.

PLoS One 2009 May 27;4(5):e5702. Epub 2009 May 27.

Experimentelle Pädiatrie, Universitätskinderklinik, Otto-von-Guericke Universität, Magdeburg, Germany.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0005702PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2682661PMC
May 2009

Epigenetic control of FOXP3 expression: the key to a stable regulatory T-cell lineage?

Nat Rev Immunol 2009 02;9(2):83-9

Department of Experimental Immunology, Helmholtz Centre for Infection Research, Braunschweig, Germany.

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http://dx.doi.org/10.1038/nri2474DOI Listing
February 2009

DNA methylation controls Foxp3 gene expression.

Eur J Immunol 2008 Jun;38(6):1654-63

Experimentelle Rheumatologie/Experimentelle Immunregulation, Charité Universitaetsmedizin Berlin, Berlin, Germany.

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http://dx.doi.org/10.1002/eji.200838105DOI Listing
June 2008

Distinctive role of CCR7 in migration and functional activity of naive- and effector/memory-like Treg subsets.

Eur J Immunol 2007 Jun;37(6):1575-83

Experimentelle Rheumatologie, Charité Universitätsmedizin Berlin, Berlin, Germany.

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http://dx.doi.org/10.1002/eji.200737201DOI Listing
June 2007

Long-term commitment to inflammation-seeking homing in CD4+ effector cells.

J Immunol 2007 Jun;178(12):8073-80

Charité, Campus Mitte, Experimentelle Rheumatologie, c/o Deutsches Rheumaforschungszentrum, 12200 Berlin, Germany.

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http://dx.doi.org/10.4049/jimmunol.178.12.8073DOI Listing
June 2007

Induction of organ-selective CD4+ regulatory T cell homing.

Eur J Immunol 2007 Apr;37(4):978-89

Experimentelle Rheumatologie, Charité Universitaetsmedizin Berlin, Berlin, Germany.

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http://dx.doi.org/10.1002/eji.200636575DOI Listing
April 2007

Selective depletion of Foxp3+ regulatory T cells induces a scurfy-like disease.

J Exp Med 2007 Jan 2;204(1):57-63. Epub 2007 Jan 2.

Institut für Medizinische Mikrobiologie, Immunologie und Hygiene, Technische Universität München, 81675 Munich, Germany.

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http://www.jem.org/lookup/doi/10.1084/jem.20061852
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http://dx.doi.org/10.1084/jem.20061852DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118432PMC
January 2007

Microenvironment-dependent requirement of STAT4 for the induction of P-selectin ligands and effector cytokines on CD4+ T cells in healthy and parasite-infected mice.

J Immunol 2006 Dec;177(11):7673-9

Charité, Campus Mitte, Experimentelle Rheumatologie, c/o Deutsches Rheumaforschungszentrum, Schumannstrasse 21/22, 10117 Berlin, Germany.

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http://dx.doi.org/10.4049/jimmunol.177.11.7673DOI Listing
December 2006

Adoptively transferred Th1 cell populations lose IFNgamma+ cells by cytokine down-regulation on single-cell level.

Immunol Lett 2006 Nov 11;107(2):176-81. Epub 2006 Oct 11.

Experimentelle Rheumatologie, Charité Campus Mitte, Berlin, Germany.

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http://dx.doi.org/10.1016/j.imlet.2006.09.003DOI Listing
November 2006

Self-limitation of Th1-mediated inflammation by IFN-gamma.

J Immunol 2006 Mar;176(5):2857-63

Experimentelle Rheumatologie, Charité Universitaetsmedizin Berlin, Campus Mitte, Berlin, Germany.

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http://dx.doi.org/10.4049/jimmunol.176.5.2857DOI Listing
March 2006

Homing to suppress: address codes for Treg migration.

Trends Immunol 2005 Dec 21;26(12):632-6. Epub 2005 Oct 21.

Experimental Rheumatology, Charité University Medicine Berlin, c/o DRFZ, Schumannstr. 21/22, 10117 Berlin, Germany.

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http://dx.doi.org/10.1016/j.it.2005.10.001DOI Listing
December 2005

Migration matters: regulatory T-cell compartmentalization determines suppressive activity in vivo.

Blood 2005 Nov 12;106(9):3097-104. Epub 2005 Jul 12.

Experimentelle Rheumatologie, Charité Universit-aetsmedizin Berlin, c/o DRFZ, Schumannstr 21/22, 10117 Berlin, Germany.

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http://dx.doi.org/10.1182/blood-2005-05-1864DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1895340PMC
November 2005

Early intrahepatic antigen-specific retention of naïve CD8+ T cells is predominantly ICAM-1/LFA-1 dependent in mice.

Hepatology 2005 Nov;42(5):1063-71

AW Morrow Gastroenterology and Liver Centre & Centenary Institute of Cancer Medicine and Cell Biology, Royal Prince Alfred Hospital, University of Sydney, Newtown, NSW, Australia.

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http://dx.doi.org/10.1002/hep.20885DOI Listing
November 2005

Expression of selectin ligands on murine effector and IL-10-producing CD4+ T cells from non-infected and infected tissues.

Eur J Immunol 2004 Nov;34(11):3070-81

Experimentelle Rheumatologie, Medizinische Klinik, Charité Universitätsmedizin Berlin, Berlin, Germany.

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http://dx.doi.org/10.1002/eji.200424972DOI Listing
November 2004

The composition of intrahepatic lymphocytes: shaped by selective recruitment?

Trends Immunol 2004 Nov;25(11):590-4

Medizinische Klinik I, Universitätsklinikum Benjamin Franklin, Hindenburgdamm 30, 12200 Berlin, Germany.

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http://dx.doi.org/10.1016/j.it.2004.09.006DOI Listing
November 2004

Bone marrow microenvironment facilitating dendritic cell: CD4 T cell interactions and maintenance of CD4 memory.

Int J Oncol 2004 Oct;25(4):867-76

Tumor Immunology Program, German Cancer Research Center, DKFZ, D-69120 Heidelberg, Germany.

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October 2004

The spectrum of lymphoid subsets preferentially recruited into the liver reflects that of resident populations.

Immunol Lett 2004 May;93(2-3):159-62

Medizinische Klinik I, Universitätsklinikum Benjamin Franklin, Hindenburgdamm 30, 12200 Berlin, Germany.

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http://dx.doi.org/10.1016/j.imlet.2004.03.007DOI Listing
May 2004

Bone marrow as a priming site for T-cell responses to blood-borne antigen.

Nat Med 2003 Sep 10;9(9):1151-7. Epub 2003 Aug 10.

Tumor Immunology Program, German Cancer Research Center (DKFZ), Heidelberg, Germany.

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http://dx.doi.org/10.1038/nm914DOI Listing
September 2003

Overlapping and selective roles of endothelial intercellular adhesion molecule-1 (ICAM-1) and ICAM-2 in lymphocyte trafficking.

J Immunol 2003 Sep;171(5):2588-93

Experimentelle Rheumatologie, Universitätsklinik Charité, Humboldt-Universität and Deutsches Rheumaforschungszentrum, Schumannstrasse 21/22, 10117 Berlin, Germany.

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http://dx.doi.org/10.4049/jimmunol.171.5.2588DOI Listing
September 2003

Role of fucosyltransferases in leukocyte trafficking: major impact for cutaneous immunity.

Trends Immunol 2003 Mar;24(3):101-4

Institute of Medical Immunology, University Hospital Charité, Humboldt University Berlin, Schumannstrasse 20-21, D-10117 Berlin, Germany.

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http://dx.doi.org/10.1016/s1471-4906(03)00024-3DOI Listing
March 2003

Expression of the chemokines MCP-1/CCL2 and RANTES/CCL5 is differentially regulated by infiltrating inflammatory cells.

Kidney Int 2002 Oct;62(4):1264-76

Division of Nephrology and Osteology, Department of Internal Medicine, University Hospital, Hamburg 20246, Germany.

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http://dx.doi.org/10.1111/j.1523-1755.2002.kid572.xDOI Listing
October 2002

Expression of the integrin alpha Ebeta 7 identifies unique subsets of CD25+ as well as CD25- regulatory T cells.

Proc Natl Acad Sci U S A 2002 Oct 19;99(20):13031-6. Epub 2002 Sep 19.

Experimentelle Rheumatologie, Universitätsklinikum Charité, Humboldt-Universität, c/o Deutsches Rheumaforschungszentrum, 10117 Berlin, Germany.

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http://www.pnas.org/cgi/doi/10.1073/pnas.192162899
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http://dx.doi.org/10.1073/pnas.192162899DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC130581PMC
October 2002

The strict regulation of lymphocyte migration to splenic white pulp does not involve common homing receptors.

Immunology 2002 Jul;106(3):299-307

Department of Molecular Cell Biology, VU University Medical Centre, Amsterdam, the Netherlands.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1782723PMC
http://dx.doi.org/10.1046/j.1365-2567.2002.01443.xDOI Listing
July 2002

In vivo differentiated cytokine-producing CD4(+) T cells express functional CCR7.

J Immunol 2002 Jun;168(11):5441-7

Experimentelle Rheumatologie, Medizinische Klinik, Charité, Germany.

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http://dx.doi.org/10.4049/jimmunol.168.11.5441DOI Listing
June 2002

Differentiation-dependent and subset-specific recruitment of T-helper cells into murine liver.

Hepatology 2002 Mar;35(3):568-78

Experimentelle Rheumatologie, Medizinische Klinik m. S. Rheumatologie, Deutsches Rheumaforschungszentrum, Schumannstrasse 21/22, 10117 Berlin, Germany.

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http://dx.doi.org/10.1053/jhep.2002.31310DOI Listing
March 2002