Alf Grandien

Alf Grandien

UNVERIFIED PROFILE

Are you Alf Grandien?   Register this Author

Register author
Alf Grandien

Alf Grandien

Publications by authors named "Alf Grandien"

Are you Alf Grandien?   Register this Author

36Publications

545Reads

31Profile Views

MYC-driven malignant transformation of mature murine B cells requires inhibition of both intrinsic apoptosis and p53 activity.

Eur J Immunol 2019 Mar 12;49(3):375-385. Epub 2018 Oct 12.

Center for Hematology and Regenerative Medicine, Karolinska Institutet, Department of Medicine, Karolinska University Hospital Huddinge, Stockholm, Sweden.

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1002/eji.201847585
Publisher Site
http://dx.doi.org/10.1002/eji.201847585DOI Listing
March 2019

Transformation of mature mouse B cells into malignant plasma cells in vitro via introduction of defined genetic elements.

Eur J Immunol 2019 Mar 4;49(3):454-461. Epub 2019 Feb 4.

Center for Hematology and Regenerative Medicine, Department of Medicine, Karolinska Institutet, Karolinska University Hospital, Huddinge, Stockholm, Sweden.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/eji.201847855DOI Listing
March 2019

Impact of over-expression in Ba/F3 cells.

Haematologica 2018 12 28;103(12):e594-e597. Epub 2018 Jun 28.

Department of Laboratory Medicine, Division of Pathology, Karolinska Institutet and Karolinska University Hospital

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3324/haematol.2018.197467DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6269285PMC
December 2018

Transformation of mouse T cells requires MYC and AKT activity in conjunction with inhibition of intrinsic apoptosis.

Oncotarget 2018 Apr 20;9(30):21396-21410. Epub 2018 Apr 20.

Center for Hematology and Regenerative Medicine, Department of Medicine, Karolinska Institutet, Karolinska University Hospital-Huddinge, 141 57 Stockholm, Sweden.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.18632/oncotarget.25113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5940390PMC
April 2018

Tumor suppressor BLU promotes TRAIL-induced apoptosis by downregulating NF-κB signaling in nasopharyngeal carcinoma.

Oncotarget 2017 Jul;8(27):43853-43865

Department of Pathophysiology and China-America Cancer Research Institute, Guangdong Provincial Key Laboratory of Medical Molecular Diagnostics, Dongguan Scientific Research Center, Guangdong Medical University, Dongguan, Guangdong, China.

View Article

Download full-text PDF

Source
http://www.oncotarget.com/fulltext/14126
Publisher Site
http://dx.doi.org/10.18632/oncotarget.14126DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5546445PMC
July 2017

Exploring the anti-apoptotic role of HAX-1 versus BCL-XL in cytokine-dependent bone marrow-derived cells from mice.

FEBS Lett 2014 Aug 6;588(17):2921-7. Epub 2014 Jun 6.

Division of Molecular Toxicology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.febslet.2014.05.042DOI Listing
August 2014

TLR activation regulates damage-associated molecular pattern isoforms released during pyroptosis.

EMBO J 2013 Jan 7;32(1):86-99. Epub 2012 Dec 7.

Department of Medicine, Center for Infectious Medicine, Karolinska Institutet, Karolinska University Hospital Huddinge, Stockholm, Sweden.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/emboj.2012.328DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3545309PMC
January 2013

Retraction: Tripeptidyl-peptidase II controls DNA damage responses and in vivo γ-irradiation resistance of tumors. Cancer Research 2007;67:7165–74.

Cancer Res 2010 Dec;70(24):10485

Center for Molecular Medicine (CMM), Karolinska Universitetssjukhuset, Stockholm, Sweden.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/0008-5472.CAN-10-3913DOI Listing
December 2010

Hematopoiesis in the thymidine kinase 2 deficient mouse model of mitochondrial DNA depletion syndrome.

J Inherit Metab Dis 2010 Jun 4;33(3):231-6. Epub 2010 May 4.

Clinical Microbiology F68, Department of Laboratory Medicine, Karolinska Institute, Karolinska University Hospital Huddinge, Stockholm, Sweden.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s10545-010-9102-xDOI Listing
June 2010

Transmission of Toxoplasma gondii from infected dendritic cells to natural killer cells.

Infect Immun 2009 Mar 12;77(3):970-6. Epub 2009 Jan 12.

Department of Medicine, Center for Infectious Medicine, Karolinska Institutet, F59, Karolinska University Hospital Huddinge, Stockholm, Sweden.

View Article

Download full-text PDF

Source
http://iai.asm.org/cgi/doi/10.1128/IAI.00833-08
Publisher Site
http://dx.doi.org/10.1128/IAI.00833-08DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2643636PMC
March 2009

Host strain-dependent difference in susceptibility in a rat model of herpes simplex type 1 encephalitis.

J Neurovirol 2008 Apr;14(2):102-18

Department of Medicine, Infectious Diseases Unit, CNS Group, Karolinska University Hospital, CMM, L8:01, SE-171 76 Stockholm, Sweden.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/13550280701883832DOI Listing
April 2008

Death receptor ligation or exposure to perforin trigger rapid egress of the intracellular parasite Toxoplasma gondii.

J Immunol 2007 Dec;179(12):8357-65

Center for Infectious Medicine, Department of Medicine, Karolinska Institutet, Karolinska University Hospital-Huddinge, Stockholm, Sweden.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4049/jimmunol.179.12.8357DOI Listing
December 2007

Tripeptidyl-peptidase II controls DNA damage responses and in vivo gamma-irradiation resistance of tumors.

Cancer Res 2007 Aug;67(15):7165-74

Center for Infectious Medicine, Department of Medicine, Karolinska Institutet, Karolinska University Hospital-Huddinge.

View Article

Download full-text PDF

Source
http://cancerres.aacrjournals.org/cgi/doi/10.1158/0008-5472.
Publisher Site
http://dx.doi.org/10.1158/0008-5472.CAN-06-4094DOI Listing
August 2007

Severe defect in thymic development in an insertional mutant mouse model.

J Immunol 2007 Apr;178(8):5018-27

Center for Infectious Medicine, Department of Medicine, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4049/jimmunol.178.8.5018DOI Listing
April 2007

Leukemia inhibitor factor (LIF) inhibits HIV-1 replication via restriction of stat 3 activation.

AIDS Res Hum Retroviruses 2007 Mar;23(3):398-406

Center for Infectious Medicine, Department of Medicine, Karolinska University Hospital Huddinge, Karolinska Institutet, Stockholm, Sweden.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1089/aid.2006.0100DOI Listing
March 2007

Drug-induced death of the asexual blood stages of Plasmodium falciparum occurs without typical signs of apoptosis.

Microbes Infect 2006 May 18;8(6):1560-8. Epub 2006 Apr 18.

Department of Immunology Wenner-Gren Institute, Stockholm University, Stockholm, Sweden.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.micinf.2006.01.016DOI Listing
May 2006

Aberrant mitochondrial iron distribution and maturation arrest characterize early erythroid precursors in low-risk myelodysplastic syndromes.

Blood 2005 Jul 8;106(1):247-53. Epub 2005 Mar 8.

Department of Medicine, Division of Hematology, Karolinska Institutet, Karolinska University Hospital Huddinge, S-141 86 Stockholm, Sweden.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1182/blood-2004-12-4649DOI Listing
July 2005

Impact of FASL-induced apoptosis in the elimination of tumor cells by NK cells.

Mol Immunol 2005 Feb;42(4):495-9

Department of Medicine, Center for Infectious Medicine, Karolinska Institutet, Karolinska University Hospital Huddinge, S-141 86 Stockholm, Sweden.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.molimm.2004.07.033DOI Listing
February 2005

CD4+ T cells kill Id+ B-lymphoma cells: FasLigand-Fas interaction is dominant in vitro but is redundant in vivo.

Cancer Immunol Immunother 2004 Dec;53(12):1135-45

Institute of Immunology, University of Oslo, Rikshospitalet, N-0027 Oslo, Norway.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00262-004-0538-4DOI Listing
December 2004

NK cell TRAIL eliminates immature dendritic cells in vivo and limits dendritic cell vaccination efficacy.

J Immunol 2004 Jan;172(1):123-9

Cancer Immunology Program, Peter MacCallum Cancer Centre, East Melbourne, Victoria, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4049/jimmunol.172.1.123DOI Listing
January 2004

Regulation of perforin-independent NK cell-mediated cytotoxicity.

Eur J Immunol 2003 Oct;33(10):2727-35

Microbiology and Tumor Biology Center, Karolinska Institutet, Stockholm, Sweden.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/eji.200324070DOI Listing
October 2003

cIAP-2 block apoptotic events in bladder cancer cells.

Anticancer Res 2003 Jul-Aug;23(4):3311-6

Department of Immunology, Wenner-Gren Institute, Stockholm University, S-106 91 Stockholm, Sweden.

View Article

Download full-text PDF

Source
September 2003

High level of cFLIP correlates with resistance to death receptor-induced apoptosis in bladder carcinoma cells.

Anticancer Res 2003 Mar-Apr;23(2B):1213-8

Department of Immunology, Wenner-Gren Institute, Stockholm University, S-106 91 Stockholm, Sweden.

View Article

Download full-text PDF

Source
July 2003

Upregulation of the apoptosis regulators cFLIP, CD95 and CD95 ligand in peripheral blood mononuclear cells in relapsing-remitting multiple sclerosis.

J Neuroimmunol 2003 Feb;135(1-2):126-34

Department of Neurology, Neurotec Department, Karolinska Institute at Huddinge University Hospital, R54, SE-141 86, Stockholm, Sweden.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/s0165-5728(02)00437-xDOI Listing
February 2003