Alexey Palamarchuk

Alexey Palamarchuk

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Alexey Palamarchuk

Alexey Palamarchuk

Publications by authors named "Alexey Palamarchuk"

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26Publications

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Abrogation of esophageal carcinoma development in miR-31 knockout rats.

Proc Natl Acad Sci U S A 2020 Mar 2;117(11):6075-6085. Epub 2020 Mar 2.

Department of Cancer Biology and Genetics, Comprehensive Cancer Center, The Ohio State University, Columbus, OH 43210;

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http://dx.doi.org/10.1073/pnas.1920333117DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7084137PMC
March 2020

Dysregulation of different classes of tRNA fragments in chronic lymphocytic leukemia.

Proc Natl Acad Sci U S A 2019 11 13;116(48):24252-24258. Epub 2019 Nov 13.

Department of Cancer Biology and Genetics, The Ohio State University, Columbus, OH 43210;

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http://dx.doi.org/10.1073/pnas.1913695116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6883801PMC
November 2019

dysregulation to identify therapeutic target combinations for chronic lymphocytic leukemia.

Proc Natl Acad Sci U S A 2017 10 18;114(40):10731-10736. Epub 2017 Sep 18.

Department of Cancer Biology and Medical Genetics, The Ohio State University, Columbus, OH 43210;

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http://dx.doi.org/10.1073/pnas.1708264114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5635897PMC
October 2017

Dysregulation of a family of short noncoding RNAs, tsRNAs, in human cancer.

Proc Natl Acad Sci U S A 2016 May 11;113(18):5071-6. Epub 2016 Apr 11.

Department of Molecular Virology, Immunology and Medical Genetics, The Ohio State University, Columbus, OH 43210; Ohio State University Comprehensive Cancer Center, Columbus, OH 43210;

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http://www.pnas.org/content/113/18/5071.full.pdf
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http://dx.doi.org/10.1073/pnas.1604266113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4983805PMC
May 2016

A Sleeping Beauty screen reveals NF-kB activation in CLL mouse model.

Blood 2013 May 16;121(21):4355-8. Epub 2013 Apr 16.

Department of Molecular Virology, Immunology and Medical Genetics and Comprehensive Cancer Center, The Ohio State University, Columbus, OH 43210, USA.

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http://dx.doi.org/10.1182/blood-2013-02-486035DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3663428PMC
May 2013

Tcl1 protein functions as an inhibitor of de novo DNA methylation in B-cell chronic lymphocytic leukemia (CLL).

Proc Natl Acad Sci U S A 2012 Feb 30;109(7):2555-60. Epub 2012 Jan 30.

Human Cancer Genetics Program and Department of Molecular Virology, Immunology and Medical Genetics, Ohio State University School of Medicine, Columbus, OH 43210, USA.

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http://dx.doi.org/10.1073/pnas.1200003109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3289317PMC
February 2012

NOTCH1 mutations in CLL associated with trisomy 12.

Blood 2012 Jan 15;119(2):329-31. Epub 2011 Nov 15.

Department of Molecular Virology, Immunology and Medical Genetics, Comprehensive Cancer Center, The Ohio State University, Columbus, USA.

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http://dx.doi.org/10.1182/blood-2011-10-386144DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3257004PMC
January 2012

IRF4 mutations in chronic lymphocytic leukemia.

Blood 2011 Sep 25;118(10):2827-9. Epub 2011 Jul 25.

Department of Molecular Virology, Immunology and Medical Genetics, Comprehensive Cancer Center, The Ohio State University, Columbus, OH 43210, USA.

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http://dx.doi.org/10.1182/blood-2011-04-350579DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3172799PMC
September 2011

Chronic lymphocytic leukemia modeled in mouse by targeted miR-29 expression.

Proc Natl Acad Sci U S A 2010 Jul 21;107(27):12210-5. Epub 2010 Jun 21.

Department of Molecular Virology, Ohio State University School of Medicine, Ohio State University, Columbus, OH 43210, USA.

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http://dx.doi.org/10.1073/pnas.1007186107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2901490PMC
July 2010

13q14 deletions in CLL involve cooperating tumor suppressors.

Blood 2010 May 13;115(19):3916-22. Epub 2010 Jan 13.

Human Cancer Genetics Program and Comprehensive Cancer Center, Department of Molecular Virology, Immunology and Medical Genetics, School of Medicine, Ohio State University, Columbus, OH, USA

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http://dx.doi.org/10.1182/blood-2009-10-249367DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2869560PMC
May 2010

Tcl1 functions as a transcriptional regulator and is directly involved in the pathogenesis of CLL.

Proc Natl Acad Sci U S A 2008 Dec 8;105(50):19643-8. Epub 2008 Dec 8.

Human Cancer Genetics Program, Comprehensive Cancer Center, Department of Molecular Virology, Immunology, and Medical Genetics, School of Medicine, Ohio State University, Columbus, OH 43210, USA.

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http://dx.doi.org/10.1073/pnas.0810965105DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2604915PMC
December 2008

Physical association with WWOX suppresses c-Jun transcriptional activity.

Cancer Res 2006 Dec;66(24):11585-9

Department of Molecular Virology, Immunology, and Medical Genetics, Human Cancer Genetics Program, Comprehensive Cancer Center, Ohio State University, Columbus, Ohio 43210, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-06-3376DOI Listing
December 2006

Tcl1 expression in chronic lymphocytic leukemia is regulated by miR-29 and miR-181.

Cancer Res 2006 Dec;66(24):11590-3

Comprehensive Cancer Center, Human Cancer Genetics Program and Department of Molecular Virology, Immunology, and Medical Genetics, OSU School of Medicine, Ohio State University, Columbus, Ohio 43210, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-06-3613DOI Listing
December 2006

Tal1 transgenic expression reveals absence of B lymphocytes.

Cancer Res 2006 Jun;66(12):6014-7

Comprehensive Cancer Center, Human Cancer Genetics Program, OSU School of Medicine, Ohio State University, Columbus, Ohio 43210, USA.

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http://cancerres.aacrjournals.org/content/66/12/6014.full.pd
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http://cancerres.aacrjournals.org/cgi/doi/10.1158/0008-5472.
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http://dx.doi.org/10.1158/0008-5472.CAN-06-0937DOI Listing
June 2006

Akt phosphorylates and regulates Pdcd4 tumor suppressor protein.

Cancer Res 2005 Dec;65(24):11282-6

Comprehensive Cancer Center, Human Cancer Genetics Program, and Department of Molecular Virology, Immunology, and Medical Genetics, Ohio State University School of Medicine, Columbus, 43210, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-05-3469DOI Listing
December 2005

WW domain-containing proteins, WWOX and YAP, compete for interaction with ErbB-4 and modulate its transcriptional function.

Cancer Res 2005 Aug;65(15):6764-72

Human Cancer Genetics Program, Department of Molecular Virology, Immunology and Medical Genetics, Comprehensive Cancer Center, Ohio State University, Columbus, Ohio 43220, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-05-1150DOI Listing
August 2005

Akt phosphorylates Tal1 oncoprotein and inhibits its repressor activity.

Cancer Res 2005 Jun;65(11):4515-9

Human Cancer Genetics Program, Comprehensive Cancer Center, Ohio State University, Columbus, Ohio 43210, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-05-0751DOI Listing
June 2005

Physical and functional interactions between the Wwox tumor suppressor protein and the AP-2gamma transcription factor.

Cancer Res 2004 Nov;64(22):8256-61

Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, Pennsylvania, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-04-2055DOI Listing
November 2004

Fhit is a physiological target of the protein kinase Src.

Proc Natl Acad Sci U S A 2004 Mar 8;101(11):3775-9. Epub 2004 Mar 8.

Kimmel Cancer Center, Thomas Jefferson University, 233 South 10th Street, Philadelphia, PA 19107, USA.

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http://dx.doi.org/10.1073/pnas.0400481101DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC374320PMC
March 2004

FHIT as tumor suppressor: mechanisms and therapeutic opportunities.

Cancer Biol Ther 2002 May-Jun;1(3):232-6

Kimmel Cancer Center; Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA.

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http://dx.doi.org/10.4161/cbt.73DOI Listing
October 2003

FHIT: from gene discovery to cancer treatment and prevention.

Lancet Oncol 2002 Dec;3(12):748-54

Kimmel Cancer Center, Thomas Jefferson University, PA 19107, USA.

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http://dx.doi.org/10.1016/s1470-2045(02)00931-2DOI Listing
December 2002