Alexey Danilov

Alexey Danilov

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Alexey Danilov

Alexey Danilov

Publications by authors named "Alexey Danilov"

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Pharmacologic inhibition of the ubiquitin-activating enzyme induces ER stress and apoptosis in chronic lymphocytic leukemia and ibrutinib-resistant mantle cell lymphoma cells.

Leuk Lymphoma 2019 Dec 21;60(12):2946-2950. Epub 2019 May 21.

Knight Cancer Institute, Oregon Health and Science University, Portland, OR, USA.

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http://dx.doi.org/10.1080/10428194.2019.1616190DOI Listing
December 2019

Duvelisib for CLL/SLL and follicular non-Hodgkin lymphoma.

Blood 2019 Nov;134(19):1573-1577

Swedish Cancer Institute, Center for Blood Disorders and Stem Cell Transplantation, Seattle, WA; and.

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http://dx.doi.org/10.1182/blood.2019001795DOI Listing
November 2019

Assessment of copper, iron, zinc and manganese status and speciation in patients with Parkinson's disease: A pilot study.

J Trace Elem Med Biol 2019 Oct 28:126423. Epub 2019 Oct 28.

I.M. Sechenov First Moscow State Medical University (Sechenov University), Trubetskaya St., 8-2, 119991 Moscow, Russia; Peoples' Friendship University of Russia (RUDN University), Miklukho-Maklay St., 10/2, Moscow 117198, Russia.

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http://dx.doi.org/10.1016/j.jtemb.2019.126423DOI Listing
October 2019

Cyclin-Dependent Kinase-9 Is a Therapeutic Target in MYC-Expressing Diffuse Large B-Cell Lymphoma.

Mol Cancer Ther 2019 09 26;18(9):1520-1532. Epub 2019 Jun 26.

Knight Cancer Institute, Oregon Health and Science University, Portland, Oregon.

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http://dx.doi.org/10.1158/1535-7163.MCT-18-1023DOI Listing
September 2019

Relevance of Prognostic Factors in the Era of Targeted Therapies in CLL.

Curr Hematol Malig Rep 2019 Aug;14(4):302-309

Knight Cancer Institute, Oregon Health & Science University, 2720 SW Moody Ave, #2106, Portland, OR, 97201, USA.

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http://link.springer.com/10.1007/s11899-019-00511-1
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http://dx.doi.org/10.1007/s11899-019-00511-1DOI Listing
August 2019

Chemo-immunotherapy for Older Patients with Chronic Lymphocytic Leukemia - Passé Yet?

Hemasphere 2019 Aug 7;3(4):e275. Epub 2019 Aug 7.

Department of Hematology and Medical Oncology, Cleveland Clinic, Cleveland, OH.

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http://dx.doi.org/10.1097/HS9.0000000000000275DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6745924PMC
August 2019

Refractory Autoimmune Cytopenias Treated With Venetoclax.

Hemasphere 2019 Jun 4;3(3):e202. Epub 2019 Jun 4.

Oregon Health and Science University, Portland, OR.

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http://dx.doi.org/10.1097/HS9.0000000000000202DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6746017PMC
June 2019

Functional genomic landscape of acute myeloid leukaemia.

Nature 2018 10 17;562(7728):526-531. Epub 2018 Oct 17.

Knight Cancer Institute, Oregon Health & Science University, Portland, OR, USA.

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http://dx.doi.org/10.1038/s41586-018-0623-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6280667PMC
October 2018

Obinutuzumab monotherapy in previously untreated chronic lymphocytic leukemia.

Leuk Lymphoma 2018 09 18;59(9):2258-2260. Epub 2017 Dec 18.

a Oregon Health and Science University , Portland , OR , USA.

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http://dx.doi.org/10.1080/10428194.2017.1410890DOI Listing
September 2018

Ibrutinib is an effective treatment for B-cell prolymphocytic leukaemia.

Br J Haematol 2017 11 8;179(3):501-503. Epub 2016 Jul 8.

Department of Medicine, Oregon Health and Science University, Portland, OR, USA.

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http://dx.doi.org/10.1111/bjh.14224DOI Listing
November 2017

Bendamustine hydrochloride in patients with B-cell malignancies who have comorbidities - is there an optimal dose?

Expert Rev Hematol 2017 08 10;10(8):707-718. Epub 2017 Jul 10.

a Department of Internal Medicine , Oregon Health & Science University , Portland , OR , USA.

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http://dx.doi.org/10.1080/17474086.2017.1350166DOI Listing
August 2017

Role for ZAP-70 Signaling in the Differential Effector Functions of Rituximab and Obinutuzumab (GA101) in Chronic Lymphocytic Leukemia B Cells.

J Immunol 2017 08 14;199(4):1275-1282. Epub 2017 Jul 14.

Department of Microbiology and Immunology, Geisel School of Medicine at Dartmouth, Lebanon, NH 03756;

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http://dx.doi.org/10.4049/jimmunol.1602105DOI Listing
August 2017

Rapid induction of apoptosis in chronic lymphocytic leukemia cells by the microtubule disrupting agent BNC105.

Cancer Biol Ther 2016 30;17(3):291-9. Epub 2016 Jan 30.

b Department of Pharmacology and Toxicology , Geisel School of Medicine at Dartmouth , Lebanon , NH , USA.

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http://dx.doi.org/10.1080/15384047.2016.1139245DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4847999PMC
January 2017

Cardiac non-Hodgkin's lymphoma: clinical characteristics and trends in survival.

Eur J Haematol 2016 Nov 30;97(5):445-452. Epub 2016 Mar 30.

Department of Internal Medicine, Oregon Health & Sciences University, Portland, OR, USA.

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http://dx.doi.org/10.1111/ejh.12751DOI Listing
November 2016

Dinaciclib Induces Anaphase Catastrophe in Lung Cancer Cells via Inhibition of Cyclin-Dependent Kinases 1 and 2.

Mol Cancer Ther 2016 11 22;15(11):2758-2766. Epub 2016 Aug 22.

Norris Cotton Cancer Center, Geisel School of Medicine at Dartmouth, Hanover, New Hampshire, and Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire.

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http://mct.aacrjournals.org/content/early/2016/08/20/1535-71
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http://dx.doi.org/10.1158/1535-7163.MCT-16-0127DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5288839PMC
November 2016

Acute inflammatory skin reaction during neutrophil recovery after antileukemic therapy.

Cutis 2016 Oct;98(4):E13-E15

Knight Cancer Institute, Oregon Health and Science University, Portland, USA.

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October 2016

Autoimmune haemolytic anaemia occurring during ibrutinib therapy for chronic lymphocytic leukaemia--response to Rider et al.

Authors:
Alexey V Danilov

Br J Haematol 2016 Apr 20;173(2):327-8. Epub 2015 Jul 20.

Knight Cancer Institute, Oregon Health and Science University, Portland, OR, USA.

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http://doi.wiley.com/10.1111/bjh.13601
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http://dx.doi.org/10.1111/bjh.13601DOI Listing
April 2016

Carfilzomib associated thrombotic microangiopathy initially treated with therapeutic plasma exchange.

J Clin Apher 2015 Oct 21;30(5):308-10. Epub 2014 Nov 21.

Department of Medicine, Dartmouth Hitchcock Medical Center, Lebanon, New Hampshire.

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http://dx.doi.org/10.1002/jca.21371DOI Listing
October 2015

Ibrutinib is an effective treatment of autoimmune haemolytic anaemia in chronic lymphocytic leukaemia.

Br J Haematol 2015 Sep 25;170(5):734-6. Epub 2015 Feb 25.

Dartmouth-Hitchcock Medical Center, Lebanon, NH, USA.

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http://dx.doi.org/10.1111/bjh.13328DOI Listing
September 2015

Vincristine activates c-Jun N-terminal kinase in chronic lymphocytic leukaemia in vivo.

Br J Clin Pharmacol 2015 Sep 19;80(3):493-501. Epub 2015 May 19.

Department of Medicine.

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http://dx.doi.org/10.1111/bcp.12624DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4574834PMC
September 2015

MIR21 is differentially expressed in the lymphoid tissue and modulated by stromal signalling in chronic lymphocytic leukaemia.

Br J Haematol 2015 Jul 29;170(2):272-5. Epub 2015 Jan 29.

Knight Cancer Institute, Oregon Health and Science University, Portland, OR, USA.

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http://doi.wiley.com/10.1111/bjh.13282
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http://dx.doi.org/10.1111/bjh.13282DOI Listing
July 2015

CDK2 Inhibition Causes Anaphase Catastrophe in Lung Cancer through the Centrosomal Protein CP110.

Cancer Res 2015 May 25;75(10):2029-38. Epub 2015 Mar 25.

Department of Pharmacology and Toxicology, Geisel School of Medicine at Dartmouth, Hanover, New Hampshire. Department of Medicine, Geisel School of Medicine at Dartmouth, Hanover, New Hampshire. The Norris Cotton Cancer Center, Geisel School of Medicine at Dartmouth, Hanover, New Hampshire. Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire.

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http://cancerres.aacrjournals.org/content/early/2015/04/30/0
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http://cancerres.aacrjournals.org/content/early/2015/03/25/0
Web Search
http://cancerres.aacrjournals.org/cgi/doi/10.1158/0008-5472.
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http://dx.doi.org/10.1158/0008-5472.CAN-14-1494DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4433598PMC
May 2015

Targeting neddylation effectively antagonizes nuclear factor-κB in chronic lymphocytic leukemia B-cells.

Leuk Lymphoma 2015 May;56(5):1566-9

Norris Cotton Cancer Center, Dartmouth-Hitchcock Medical Center , Lebanon, NH , USA.

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http://dx.doi.org/10.3109/10428194.2014.990901DOI Listing
May 2015

A new hope: novel therapeutic approaches to treatment of chronic lymphocytic leukaemia with defects in TP53.

Br J Haematol 2014 Oct 21;167(2):149-61. Epub 2014 Jul 21.

Medicine, Dartmouth-Hitchcock Medical Center, Lebanon, NH, USA.

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http://dx.doi.org/10.1111/bjh.13042DOI Listing
October 2014

Gossypol increases expression of the pro-apoptotic BH3-only protein NOXA through a novel mechanism involving phospholipase A2, cytoplasmic calcium, and endoplasmic reticulum stress.

J Biol Chem 2014 Jun 28;289(23):16190-9. Epub 2014 Apr 28.

From the Departments of Pharmacology and Toxicology and the Norris Cotton Cancer Center, Geisel School of Medicine at Dartmouth, Lebanon, New Hampshire 03756

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http://dx.doi.org/10.1074/jbc.M114.562900DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4047389PMC
June 2014

The Nedd8-activating enzyme inhibitor MLN4924 thwarts microenvironment-driven NF-κB activation and induces apoptosis in chronic lymphocytic leukemia B cells.

Clin Cancer Res 2014 Mar;20(6):1576-89

Authors' Affiliations: Departments of Medicine and Pathology, Dartmouth-Hitchcock Medical Center, Lebanon; Department of Pharmacology and Toxicology, Geisel School of Medicine at Dartmouth, Hanover, New Hampshire; and Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts.

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http://dx.doi.org/10.1158/1078-0432.CCR-13-0987DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3960291PMC
March 2014

The putative BH3 mimetic S1 sensitizes leukemia to ABT-737 by increasing reactive oxygen species, inducing endoplasmic reticulum stress, and upregulating the BH3-only protein NOXA.

Apoptosis 2014 Jan;19(1):201-9

Department of Pharmacology and Toxicology, Norris Cotton Cancer Center, Geisel School of Medicine at Dartmouth, Rubin Building Level 6, One Medical Center Drive, Lebanon, NH, 03756, USA.

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http://dx.doi.org/10.1007/s10495-013-0910-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3947354PMC
January 2014

Toward a cure for chronic lymphocytic leukemia: an attack on multiple fronts.

Expert Rev Anticancer Ther 2013 Sep;13(9):1009-12

Medicine, Dartmouth-Hitchcock Medical Center, Geisel School of Medicine at Dartmouth, Lebanon, NH, USA.

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http://dx.doi.org/10.1586/14737140.2013.825424DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3910377PMC
September 2013

Targeted therapy in chronic lymphocytic leukemia: past, present, and future.

Authors:
Alexey V Danilov

Clin Ther 2013 Sep;35(9):1258-70

Department of Medicine, Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire. Electronic address:

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http://dx.doi.org/10.1016/j.clinthera.2013.08.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3880015PMC
September 2013

Vinblastine rapidly induces NOXA and acutely sensitizes primary chronic lymphocytic leukemia cells to ABT-737.

Mol Cancer Ther 2013 Aug 30;12(8):1504-14. Epub 2013 May 30.

Departments of Pharmacology and Toxicology, Geisel School of Medicine at Dartmouth, Lebanon, NH, USA.

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http://dx.doi.org/10.1158/1535-7163.MCT-12-1197DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3742582PMC
August 2013

Brentuximab vedotin demonstrates activity in a patient with plasmablastic lymphoma arising from a background of chronic lymphocytic leukemia.

J Clin Oncol 2013 Apr 18;31(12):e197-9. Epub 2013 Mar 18.

Dartmouth-Hitchcock Medical Center, One Medical Center Dr, Lebanon, NH 03756, USA.

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http://dx.doi.org/10.1200/JCO.2012.46.9593DOI Listing
April 2013

Dipeptidyl peptidase 2 apoptosis assay determines the B-cell activation stage and predicts prognosis in chronic lymphocytic leukemia.

Exp Hematol 2010 Dec 24;38(12):1167-77. Epub 2010 Sep 24.

Tufts Medical Center, Department of Pathology,Tufts University School of Medicine, 150 Harrison Avenue, Boston, MA 02111, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S0301472X1000372
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http://dx.doi.org/10.1016/j.exphem.2010.08.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2991601PMC
December 2010

Managing a pregnant patient with paroxysmal nocturnal hemoglobinuria in the era of eculizumab.

Leuk Res 2010 May 1;34(5):566-71. Epub 2009 Dec 1.

Department of Hematology and Oncology, Tufts Medical Center, 800 Washington St, Boston, MA 02111, USA.

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http://dx.doi.org/10.1016/j.leukres.2009.10.025DOI Listing
May 2010

AIDS-related Burkitt lymphoma--a heterogeneous disease?

Leuk Res 2008 Dec 9;32(12):1939-41. Epub 2008 May 9.

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http://dx.doi.org/10.1016/j.leukres.2008.03.037DOI Listing
December 2008

Cell technologies in immunotherapy of cancer.

Adv Exp Med Biol 2007 ;601:387-93

Prof. N.N. Petrov Research Institute of Oncology, Department of Biotherapy and Bone Marrow Transplantation, Saint-Petersburg, Russia.

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http://dx.doi.org/10.1007/978-0-387-72005-0_42DOI Listing
October 2007

Molecular pathogenesis of chronic lymphocytic leukemia.

Curr Mol Med 2006 Sep;6(6):665-75

Department of Internal Medicine, Memorial Hospital of Rhode Island, Brown University School of Medicine, Pawtucket, USA.

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http://dx.doi.org/10.2174/156652406778195008DOI Listing
September 2006

Differential control of G0 programme in chronic lymphocytic leukaemia: a novel prognostic factor.

Br J Haematol 2005 Feb;128(4):472-81

Department of Pathology, Tufts University School of Medicine, Boston, MA 02111, USA.

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http://dx.doi.org/10.1111/j.1365-2141.2004.05346.xDOI Listing
February 2005