Alexandre Reuben

Alexandre Reuben

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Alexandre Reuben

Alexandre Reuben

Publications by authors named "Alexandre Reuben"

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Concepts Collide: Genomic, Immune, and Microbial Influences on the Tumor Microenvironment and Response to Cancer Therapy.

Front Immunol 2018 4;9:946. Epub 2018 May 4.

Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, United States.

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http://dx.doi.org/10.3389/fimmu.2018.00946DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5945998PMC
July 2019

The Influence of the Gut Microbiome on Cancer, Immunity, and Cancer Immunotherapy.

Cancer Cell 2018 04;33(4):570-580

Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, 1400 Pressler Street, Unit Number 1484, 1515 Holcombe Boulevard, Houston, TX 77030, USA; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Unit 1954, 1881 East Road, Houston, Texas 77054, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2018.03.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6529202PMC
April 2018

The hemochromatosis protein HFE 20 years later: An emerging role in antigen presentation and in the immune system.

Immun Inflamm Dis 2017 09 19;5(3):218-232. Epub 2017 Apr 19.

Centre de Recherche du Centre Hospitalier de l'Université de Montréal (CRCHUM), Montréal, Québec, Canada.

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http://dx.doi.org/10.1002/iid3.158DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5569368PMC
September 2017

Toward a Molecular-Genetic Classification of Spitzoid Neoplasms.

Clin Lab Med 2017 09;37(3):431-448

Section of Dermatopathology, Department of Pathology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Unit 85, Houston, TX, USA; Department of Dermatology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Unit 85, Houston, TX, USA.

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http://dx.doi.org/10.1016/j.cll.2017.05.003DOI Listing
September 2017

An adaptive signaling network in melanoma inflammatory niches confers tolerance to MAPK signaling inhibition.

J Exp Med 2017 06 27;214(6):1691-1710. Epub 2017 Apr 27.

Manchester Cancer Research Centre, Faculty of Biology, Medicine, and Health, School of Medical Sciences, Division of Molecular and Clinical Cancer Studies, The University of Manchester, Manchester M13 9PT, England, UK

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http://dx.doi.org/10.1084/jem.20160855DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5460994PMC
June 2017

Interaction of molecular alterations with immune response in melanoma.

Cancer 2017 06;123(S11):2130-2142

Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas.

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http://dx.doi.org/10.1002/cncr.30681DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6105277PMC
June 2017

Targeted Therapies Combined With Immune Checkpoint Therapy.

Cancer J 2016 Mar-Apr;22(2):138-46

From the Departments of *Surgical Oncology and †Genomic Medicine, University of Texas M. D. Anderson Cancer Center, Houston, TX.

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http://dx.doi.org/10.1097/PPO.0000000000000182DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6478395PMC
January 2017

Gene Targeting Meets Cell-Based Therapy: Raising the Tail, or Merely a Whimper?

Clin Cancer Res 2017 Jan 11;23(2):327-329. Epub 2016 Nov 11.

Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas.

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http://dx.doi.org/10.1158/1078-0432.CCR-16-2493DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5241203PMC
January 2017

Monitoring immune responses in the tumor microenvironment.

Curr Opin Immunol 2016 08 27;41:23-31. Epub 2016 May 27.

Department of Genitourinary Medical Oncology, The University of Texas MD Anderson Cancer Center, 1155 Pressler Street, Unit 1374, Houston, TX 77030, USA. Electronic address:

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http://dx.doi.org/10.1016/j.coi.2016.05.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5257261PMC
August 2016

Update on use of aldesleukin for treatment of high-risk metastatic melanoma.

Immunotargets Ther 2015 7;4:79-89. Epub 2015 Apr 7.

Department of Surgical Oncology, University of Texas MD Anderson Cancer Center, Houston, TX, USA; Department of Genomic Medicine, University of Texas MD Anderson Cancer Center, Houston, TX, USA.

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http://dx.doi.org/10.2147/ITT.S61590DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4918260PMC
July 2016

Influences of BRAF Inhibitors on the Immune Microenvironment and the Rationale for Combined Molecular and Immune Targeted Therapy.

Curr Oncol Rep 2016 07;18(7):42

Department of Surgical Oncology, Genomic Medicine, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX, 77030, USA.

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http://dx.doi.org/10.1007/s11912-016-0531-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5330383PMC
July 2016

Working with Human Tissues for Translational Cancer Research.

J Vis Exp 2015 Nov 26(105). Epub 2015 Nov 26.

Department of Surgical Oncology, University of Texas MD Anderson Cancer Center;

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http://dx.doi.org/10.3791/53189DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4692755PMC
November 2015

Raising the bar: optimizing combinations of targeted therapy and immunotherapy.

Ann Transl Med 2015 Oct;3(18):272

1 Department of Surgical Oncology; 2 Department of Genomic Medicine, the University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA.

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http://dx.doi.org/10.3978/j.issn.2305-5839.2015.10.28DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4630548PMC
October 2015

Immune Effects of Chemotherapy, Radiation, and Targeted Therapy and Opportunities for Combination With Immunotherapy.

Semin Oncol 2015 Aug 3;42(4):601-16. Epub 2015 Jun 3.

Department of Medical Oncology, Massachusetts General Hospital and Harvard Medical School, Boston, MA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00937754150010
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http://dx.doi.org/10.1053/j.seminoncol.2015.05.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4955940PMC
August 2015

Does It MEK a Difference? Understanding Immune Effects of Targeted Therapy.

Clin Cancer Res 2015 Jul 29;21(14):3102-4. Epub 2015 May 29.

Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas. Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas.

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http://dx.doi.org/10.1158/1078-0432.CCR-15-0363DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4506225PMC
July 2015

T lymphocyte-derived TNF and IFN-γ repress HFE expression in cancer cells.

Mol Immunol 2015 Jun 18;65(2):259-66. Epub 2015 Feb 18.

Centre de recherche du Centre hospitalier de l'Université de Montréal (CRCHUM) and Institut du cancer de Montréal, Montréal, Québec, Canada H2X 0A9; Département de Médecine, Université de Montréal, Montréal, Québec, Canada H3C 3J7. Electronic address:

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http://dx.doi.org/10.1016/j.molimm.2015.01.029DOI Listing
June 2015

Combining targeted therapy and immune checkpoint inhibitors in the treatment of metastatic melanoma.

Cancer Biol Med 2014 Dec;11(4):237-46

1 Department of Surgery, Massachusetts General Hospital, Boston, MA 02114, USA ; 2 Harvard Medical School, Boston, MA 02115, USA ; 3 Department of Melanoma Medical Oncology, 4 Department of Genomic Medicine, 5 Department of Surgical Oncology, University of Texas M.D. Anderson Cancer Center, Houston, TX 77030, USA.

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http://dx.doi.org/10.7497/j.issn.2095-3941.2014.04.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4296084PMC
December 2014

RAF Inhibitor Therapy Promotes Melanocytic Antigen Expression and Enhanced Anti-Tumor Immunity in Melanoma.

J Pigment Disord 2014 Nov 16;1(5). Epub 2014 Oct 16.

Division of Surgical Oncology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX 77030, USA.

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http://omicsgroup.org/journals/raf-inhibitor-therapy-promote
Publisher Site
http://dx.doi.org/10.4172/2376-0427.1000139DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5731654PMC
November 2014

Evidence of synergy with combined BRAF-targeted therapy and immune checkpoint blockade for metastatic melanoma.

Oncoimmunology 2014 Oct 13;3(9):e954956. Epub 2014 Dec 13.

Division of Surgical Oncology; The University of Texas MD Anderson Cancer Center ; Houston, TX USA ; Genomic Medicine; The University of Texas MD Anderson Cancer Center ; Houston, TX USA.

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http://dx.doi.org/10.4161/21624011.2014.954956DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4292518PMC
October 2014

The WT hemochromatosis protein HFE inhibits CD8⁺ T-lymphocyte activation.

Eur J Immunol 2014 Jun 20;44(6):1604-14. Epub 2014 Mar 20.

Centre de recherche du Centre hospitalier de l'Université de Montréal (CRCHUM) Institut du cancer de Montréal, Montréal, Québec, Canada; Département de Médecine, Université de Montréal, Montréal, Québec, Canada.

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http://dx.doi.org/10.1002/eji.201343955DOI Listing
June 2014

Stimulation of Wnt/ß-catenin pathway in human CD8+ T lymphocytes from blood and lung tumors leads to a shared young/memory phenotype.

PLoS One 2012 30;7(7):e41074. Epub 2012 Jul 30.

Research Centre, Centre Hospitalier de l'Université de Montréal, Université de Montréal and Institut du Cancer de Montréal, Hôpital Notre-Dame, Montréal, Québec, Canada.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0041074PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3408435PMC
April 2013

Polyfunctionality of a DKK1 self-antigen-specific CD8(+) T lymphocyte clone in lung cancer.

Cancer Immunol Immunother 2011 Aug 17;60(8):1119-25. Epub 2011 Jun 17.

Department of Medicine, Centre de recherche, Centre hospitalier de l'Université de Montréal, Hôpital Notre-Dame, Université de Montréal, and Institut du Cancer de Montréal, Pavillon JA DeSève, Room Y-5605, 2099 rue Alexandre DeSève, Montréal, QC, Canada.

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http://dx.doi.org/10.1007/s00262-011-1055-xDOI Listing
August 2011