Publications by authors named "Alexandre Alanio"

99Publications

Risk factors associated with COVID-19-associated pulmonary aspergillosis in ICU patients: a French multicentric retrospective cohort.

Clin Microbiol Infect 2020 Dec 13. Epub 2020 Dec 13.

Université de Paris, Laboratoire de Parasitologie-Mycologie, Groupe Hospitalier Saint-Louis-Lariboisière-Fernand-Widal, Assistance Publique-Hôpitaux de Paris (AP-HP), Paris, France; Molecular Mycology Unit, CNRS UMR2000, National Reference Centre for Invasive Mycoses and Antifungals (NRCMA), Institut Pasteur, Paris, France. Electronic address:

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December 2020

Fungal infections should be part of the core outcome set for COVID-19.

Lancet Infect Dis 2020 Dec 7. Epub 2020 Dec 7.

Mycology-Parasitology Department, Hôpital Saint-Louis, Molecular Mycology Unit, CNRS UMR2000, National Reference Centre for Invasive Mycoses and Antifungals, Institut Pasteur, Université de Paris, Paris, France.

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December 2020

Comparison of MultiLocus Sequence Typing (MLST) and Microsatellite Length Polymorphism (MLP) for genotyping.

Comput Struct Biotechnol J 2020 15;18:2890-2896. Epub 2020 Oct 15.

Laboratoire de Parasitologie-Mycologie; AP-HP, Groupe Hospitalier Saint-Louis-Lariboisière-Fernand-Widal, Paris, France.

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October 2020

The presence of Pneumocystis jirovecii in critically ill patients with COVID-19.

J Infect 2020 Nov 4. Epub 2020 Nov 4.

Laboratoire de Parasitologie-Mycologie AP-HP, Groupe Hospitalier Saint-Louis-Lariboisière-Fernand-Widal, Université de Paris, Institut Pasteur, CNRS UMR2000, Unité de Mycologie Moléculaire, Centre National de Référence Mycoses Invasives et Antifongiques.

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November 2020

Entamoeba histolytica DNA Detection in Serum from Patients with Suspected Amoebic Liver Abscess.

J Clin Microbiol 2020 Sep 22;58(10). Epub 2020 Sep 22.

Laboratoire de Parasitologie-Mycologie, Groupe Hospitalier Saint-Louis Lariboisière Fernand-Widal, Assistance Publique-Hôpitaux de Paris (AP-HP), Paris, France.

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September 2020

Evaluation of the COVID-19 IgG/IgM Rapid Test from Orient Gene Biotech.

J Clin Microbiol 2020 07 23;58(8). Epub 2020 Jul 23.

Université de Paris, Département des Agents Infectieux, Service de Virologie, Hôpital Saint-Louis, Paris, France.

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July 2020

Dormancy in Cryptococcus neoformans: 60 years of accumulating evidence.

Authors:
Alexandre Alanio

J Clin Invest 2020 Jul;130(7):3353-3360

Laboratoire de Parasitologie-Mycologie, Groupe Hospitalier Saint-Louis-Lariboisière-Fernand-Widal, Assistance Publique-Hôpitaux de Paris (AP-HP), Paris, France.

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July 2020

Prevalence of putative invasive pulmonary aspergillosis in critically ill patients with COVID-19.

Lancet Respir Med 2020 06 20;8(6):e48-e49. Epub 2020 May 20.

Réanimation Médicale et Toxicologique, Assistance Publique-Hôpitaux de Paris, Groupe Hospitalier Saint-Louis-Lariboisière-Fernand-Widal, Paris, France; Université de Paris, Paris, France; Institut National de la Santé et de la Recherche Médicale, Paris, France.

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June 2020

Tracking a Global Threat: a New Genotyping Method for Candida auris.

mBio 2020 03 10;11(2). Epub 2020 Mar 10.

Institut Pasteur, Molecular Mycology Unit, CNRS UMR2000, National Reference Center for Invasive Mycoses and Antifungals (NRCMA), Paris, France.

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March 2020

Failure of multiplex meningitis/encephalitis (ME) NAT during cryptococcal meningitis in solid organ recipients.

Transpl Infect Dis 2020 Aug 11;22(4):e13263. Epub 2020 Jun 11.

Service de Maladies Infectieuses et Tropicales, Centre d'Infectiologie Necker-Pasteur, Hôpital Necker-Enfants Malades, Assistance Publique des Hôpitaux de Paris (AP-HP), Université de Paris, Paris, France.

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August 2020

Aspergillus flavus malignant external otitis in a diabetic patient: case report and literature review.

Infection 2020 Apr 8;48(2):193-203. Epub 2020 Feb 8.

Service de Maladies Infectieuses Et Tropicales, APHP, Hôpital Bichat-Claude Bernard, 46, rue Henri Huchard, 75018, Paris, France.

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April 2020

Deep cutaneous fungal infections in solid-organ transplant recipients.

J Am Acad Dermatol 2020 Aug 11;83(2):455-462. Epub 2020 Jan 11.

Unit of Dermatology, DMU3ID, Pitié-Salpêtrière Hospital, AP-HP, Sorbonne University, Paris, France. Electronic address:

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August 2020

Quantification of : Cross-Platform Comparison of One qPCR Assay with Leading Platforms and Six Master Mixes.

J Fungi (Basel) 2019 Dec 26;6(1). Epub 2019 Dec 26.

Laboratoire de Parasitologie-Mycologie, Groupe Hospitalier Saint-Louis-Lariboisière-Fernand-Widal, Assistance Publique-Hôpitaux de Paris (AP-HP), Université de Paris, 75475 Paris, France.

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December 2019

Outbreak-Causing Fungi: Pneumocystis jirovecii.

Mycopathologia 2020 Oct 28;185(5):783-800. Epub 2019 Nov 28.

Laboratoire de Parasitologie-Mycologie, Groupe Hospitalier Saint-Louis-Lariboisière-Fernand-Widal, Assistance Publique-Hôpitaux de Paris (AP-HP), Université de Paris, Paris, France.

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October 2020

Global guideline for the diagnosis and management of mucormycosis: an initiative of the European Confederation of Medical Mycology in cooperation with the Mycoses Study Group Education and Research Consortium.

Lancet Infect Dis 2019 12 5;19(12):e405-e421. Epub 2019 Nov 5.

Department of Medical Microbiology, Postgraduate Institute of Medical Education & Research, Chandigarh, India.

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December 2019

New Insights Into Cryptococcus Spp. Biology and Cryptococcal Meningitis.

Curr Neurol Neurosci Rep 2019 10 31;19(10):81. Epub 2019 Oct 31.

Molecular Mycology Unit, UMR2000, CNRS, Institut Pasteur, 25 - 28 Rue du Dr Roux, 75015, Paris, France.

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October 2019

Time to and differential time to blood culture positivity for assessing catheter-related yeast fungaemia: A longitudinal, 7-year study in a single university hospital.

Mycoses 2020 Jan 3;63(1):95-103. Epub 2019 Nov 3.

Parasitology-Mycology Laboratory, Lariboisière Saint-Louis Fernand Widal Hospital, Assistance Publique-Hôpitaux de Paris (AP-HP), Paris, France.

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January 2020

Intranasal Inoculation of Cryptococcus neoformans in Mice Produces Nasal Infection with Rapid Brain Dissemination.

mSphere 2019 08 7;4(4). Epub 2019 Aug 7.

W. Harry Feinstone Department of Molecular Microbiology and Immunology, Johns Hopkins University Bloomberg School of Public Health, Baltimore, Maryland, USA

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August 2019

Recent advances in managing HIV-associated cryptococcal meningitis.

F1000Res 2019 28;8. Epub 2019 May 28.

Molecular Mycology Unit and National Reference Centre for Invasive Mycoses, UMR2000, CNRS, Institut Pasteur, Paris, France.

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June 2020

The enigmatic role of fungal annexins: the case of Cryptococcus neoformans.

Microbiology (Reading) 2019 08 29;165(8):852-862. Epub 2019 May 29.

W. Harry Feinstone Department of Molecular Microbiology and Immunology, Johns Hopkins University Bloomberg School of Public Health, Baltimore MD, USA.

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August 2019

Emerging mould infections: Get prepared to meet unexpected fungi in your patient.

Med Mycol 2020 Feb;58(2):156-162

Université de Paris, Laboratoire de Parasitologie-Mycologie, AP-HP, Groupe Hospitalier Saint-Louis-Lariboisière-Fernand-Widal, Paris, France.

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February 2020

Why are so many cases of invasive aspergillosis missed?

Med Mycol 2019 Apr;57(Supplement_2):S94-S103

Department of Infectious Diseases and Tropical Medicine, Necker-Pasteur Infectious Diseases Center, Necker-Enfants Malades University Hospital, Assistance Publique-Hôpitaux de Paris (AP-HP), Institut Imagine, Paris Descartes University, Paris, France.

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April 2019

Corrigendum: Continuous Decline of Seroprevalence in Hospital: A 1997-2014 Longitudinal Study in Paris, France.

Front Microbiol 2018 27;9:2814. Epub 2018 Nov 27.

Laboratoire de Parasitologie-Mycologie, AP-HP, Groupe Hospitalier Saint-Louis, Lariboisière, Fernand-Widal, Paris, France.

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November 2018

Reactivation of dormant/latent fungal infection.

J Infect 2018 12 6;77(6):463-468. Epub 2018 Jul 6.

INSERM U1070, Université de Poitiers, Poitiers, France; Faculté de médecine et pharmacie, Université de Poitiers, Poitiers, France; Service de maladies infectieuses et tropicales, CHU de Poitiers, Poitiers, France.

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December 2018

Recent advances in the understanding and management of mucormycosis.

F1000Res 2018 7;7. Epub 2018 Sep 7.

Paris Descartes University, Sorbonne Paris Cité, Infectious Diseases Unit, Necker-Enfants Malades University Hospital, AP-HP, Imagine Institute, Paris, France.

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February 2019

Failure of voriconazole therapy due to acquired azole resistance in Aspergillus fumigatus in a kidney transplant recipient with chronic necrotizing aspergillosis.

Am J Transplant 2018 09 12;18(9):2352-2355. Epub 2018 Jul 12.

Infectious Diseases Department, Necker Hospital, Public Assistance/Paris Hospitals, University Paris Descartes, Paris, France.

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September 2018

Mechanisms of -Mediated Host Damage.

Front Immunol 2018 30;9:855. Epub 2018 Apr 30.

Department of Molecular Microbiology and Immunology, Johns Hopkins School of Public Health, Baltimore, MD, United States.

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June 2019

Diagnostic and therapeutic strategies in cryptococcosis: impact on outcome.

Mem Inst Oswaldo Cruz 2018 7;113(7):e180050. Epub 2018 May 7.

Unité de Mycologie Moléculaire, Centre National de Référence Mycoses Invasives et Antifongiques, Institut Pasteur, Paris, France.

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May 2018

A cell impedance-based real-time in vitro assay to assess the toxicity of amphotericin B formulations.

Toxicol Appl Pharmacol 2017 11 1;334:18-23. Epub 2017 Sep 1.

Institut Pasteur, CNRS, Molecular Mycology unit, URA3012 Paris, France; Laboratory of Parasitology-Mycology, Saint-Louis Lariboisière Fernand Widal hospitals, Assistance Publique-Hôpitaux de Paris (AP-HP), Paris, France; Paris-Diderot, Sorbonne Paris Cité University, Paris, France.

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November 2017

Diversity of Pneumocystis jirovecii Across Europe: A Multicentre Observational Study.

EBioMedicine 2017 Aug 29;22:155-163. Epub 2017 Jun 29.

Laboratoire de Parasitologie-Mycologie, AP-HP, Groupe Hospitalier Saint-Louis-Lariboisière-Fernand-Widal, Paris, France; Université Paris Diderot, Sorbonne Paris Cité, Paris, France; Institut Pasteur, CNRS, Unité de Mycologie Moléculaire, Centre National de Référence Mycoses Invasives et Antifongiques, URA3012, Paris, France.

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August 2017

detection in asymptomatic patients: what does its natural history tell us?

F1000Res 2017 23;6:739. Epub 2017 May 23.

Parasitology-Mycology Laboratory, Lariboisière Saint-Louis Fernand Widal Hospitals, Assistance Publique-Hôpitaux de Paris, Paris, France.

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May 2017

Investigating Clinical Issues by Genotyping of Medically Important Fungi: Why and How?

Clin Microbiol Rev 2017 07;30(3):671-707

Institut Pasteur, Molecular Mycology Unit, National Reference Center for Invasive Mycoses and Antifungals, Paris, France

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July 2017

Challenges in microbiological diagnosis of invasive infections.

F1000Res 2017 17;6. Epub 2017 Feb 17.

Parasitology-Mycology Laboratory, Lariboisière Saint-Louis Fernand Widal hospitals, Assistance Publique-Hôpitaux de Paris (AP-HP), Paris, France; Paris-Diderot, Sorbonne Paris Cité University, Paris, France; Institut Pasteur, CNRS, Molecular Mycology Unit, Reference National Center of Invasive Mycoses and Antifungals, Paris, France.

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February 2017

Fluconazole and Echinocandin Resistance of Correlates Better with Antifungal Drug Exposure Rather than with Mutator Genotype in a French Cohort of Patients Harboring Low Rates of Resistance.

Front Microbiol 2016 23;7:2038. Epub 2016 Dec 23.

Laboratoire de Parasitologie-Mycologie, AP-HP, Groupe Hospitalier Saint-Louis-Lariboisière-Fernand-WidalParis, France; Université Paris Diderot, Sorbonne Paris CitéParis, France; Unité de Mycologie Moléculaire, Institut Pasteur, Centre National de la Recherche Scientifique, Centre National de Référence Mycoses Invasives et Antifongiques, URA3012Paris, France.

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December 2016

Copy Number Variation of Mitochondrial DNA Genes in Pneumocystis jirovecii According to the Fungal Load in BAL Specimens.

Front Microbiol 2016 12;7:1413. Epub 2016 Sep 12.

Laboratoire de Parasitologie-Mycologie, Groupe Hospitalier Saint-Louis-Lariboisière-Fernand-Widal, Assistance Publique - Hôpitaux de ParisParis, France; Sorbonne Paris Cité, Université Paris DiderotParis, France; Institut Pasteur, Unité de Mycologie Moléculaire, Centre National de Référence Mycoses Invasives et Antifongiques, Institut PasteurParis, France; CNRS URA3012Paris, France.

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September 2016

Performance evaluation of multiplex PCR including Aspergillus-not so simple!

Med Mycol 2017 Jan 23;55(1):56-62. Epub 2016 Sep 23.

Paris-Diderot, Sorbonne Paris Cité University

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January 2017

ECIL guidelines for the diagnosis of Pneumocystis jirovecii pneumonia in patients with haematological malignancies and stem cell transplant recipients.

J Antimicrob Chemother 2016 09 12;71(9):2386-96. Epub 2016 May 12.

Parasitology-Mycology Laboratory, Groupe Hospitalier Lariboisière Saint-Louis Fernand Widal, Assistance Publique-Hôpitaux de Paris (AP-HP), Université Paris-Diderot, Sorbonne Paris Cité, and Institut Pasteur, Unité de Mycologie Moléculaire, CNRS URA3012, Centre National de Référence Mycoses Invasives et Antifongiques, Paris, France.

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September 2016

Pneumocystis jirovecii pneumonia: still a concern in patients with haematological malignancies and stem cell transplant recipients.

J Antimicrob Chemother 2016 09 12;71(9):2379-85. Epub 2016 May 12.

Department of Haematology, Acute Leukaemia and Stem Cell Transplantation Unit, University Hospitals Leuven, Campus Gasthuisberg, Leuven, Belgium.

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September 2016

New therapeutic strategies for invasive aspergillosis in the era of azole resistance: how should the prevalence of azole resistance be defined?

J Antimicrob Chemother 2016 08;71(8):2075-8

Laboratoire de Parasitologie-Mycologie, AP-HP, Groupe Hospitalier Saint-Louis-Lariboisière-Fernand-Widal, Paris, France Paris Diderot, Sorbonne Paris Cité University, Paris, France Institut Pasteur, Molecular Mycology Unit, National Reference Centre of Invasive Mycoses and Antifungals, CNRS URA 3012, Paris, France

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August 2016

[Sinonasal fungal infections are not exclusively due to mucorales and Aspergillus!].

Ann Pathol 2016 Aug 27;36(4):245-51. Epub 2016 Jul 27.

Service d'anatomie et cytologie pathologiques, faculté de médecine, université Paris Diderot - Paris 7, AP-HP Lariboisière, 2, avenue Ambroise-Paré, 75475 Paris, France.

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August 2016

Variation in copy number of the 28S rDNA of Aspergillus fumigatus measured by droplet digital PCR and analog quantitative real-time PCR.

J Microbiol Methods 2016 08 14;127:160-163. Epub 2016 Jun 14.

Parasitology-Mycology Laboratory, Lariboisière Saint-Louis Fernand Widal Hospitals, Assistance Publique-Hôpitaux de Paris (AP-HP), France; Université Paris-Diderot, Sorbonne Paris Cité, France; Institut Pasteur, Molecular Mycology Unit, CNRS URA3012, National Reference Center of Invasive Mycoses and Antifungals, France. Electronic address:

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August 2016

Diversity of Pneumocystis jirovecii during Infection Revealed by Ultra-Deep Pyrosequencing.

Front Microbiol 2016 24;7:733. Epub 2016 May 24.

Laboratoire de Parasitologie-Mycologie, Groupe Hospitalier Saint-Louis-Lariboisière-Fernand-Widal, Assistance Publique Hôpitaux de Paris, Hôpital Saint-LouisParis, France; Université Paris Diderot, Sorbonne Paris CitéParis, France; Unité de Mycologie Moléculaire, Département de Mycologie, Centre National de Référence Mycoses Invasives et Antifongiques, Institut PasteurParis, France; Centre National de la Recherche Scientifique CNRS URA3012Paris, France.

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June 2016

Seroprevalence of Toxoplasma gondii and direct genotyping using minisequencing in free-range pigs in Burkina Faso.

Int J Food Microbiol 2016 Aug 16;230:10-5. Epub 2016 Apr 16.

Laboratoire de Parasitologie-Mycologie, Groupe hospitalier Saint Louis Lariboisière, Assistance Publique-Hôpitaux de Paris (APHP), Paris, France; Université Paris Diderot, Sorbonne Paris Cité, Paris, France. Electronic address:

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August 2016

[Cryptococcus where they are not expected: Five case reports of extra-cerebral and extra-pulmonary cryptococcosis].

Ann Pathol 2015 Dec 18;35(6):479-85. Epub 2015 Nov 18.

Unité d'histopathologie humaine et modèles animaux, Institut Pasteur, 28, rue du Dr.-Roux, 75724 Paris, France; Université Paris Descartes, PRES Sorbonne Paris Cité, 75006 Paris, France.

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December 2015

Mucormycosis: New Developments into a Persistently Devastating Infection.

Semin Respir Crit Care Med 2015 Oct 23;36(5):692-705. Epub 2015 Sep 23.

Service de Maladies Infectieuses et tropicales, APHP-Hôpital Necker-Enfants Malades, Université Paris Descartes, Sorbonne Paris Cité, IHU Imagine, Paris, France.

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October 2015

New Short Tandem Repeat-Based Molecular Typing Method for Pneumocystis jirovecii Reveals Intrahospital Transmission between Patients from Different Wards.

PLoS One 2015 1;10(5):e0125763. Epub 2015 May 1.

Laboratoire de Parasitologie-Mycologie, AP-HP, Groupe Hospitalier Saint-Louis-Lariboisière-Fernand-Widal, Paris, France; Université Paris-Diderot, Sorbonne Cité, Paris, France; Institut Pasteur, Unité de Mycologie Moléculaire, Centre National de Référence Mycoses invasives et Antifongiques, Paris, France; CNRS URA3012, Paris, France.

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January 2016

Importance of operational factors in the reproducibility of Aspergillus galactomannan enzyme immune assay.

PLoS One 2015 10;10(4):e0124044. Epub 2015 Apr 10.

Laboratoire de Parasitologie-Mycologie, Groupe hospitalier Lariboisière-Saint Louis, Assistance Publique-Hôpitaux de Paris (APHP), Paris, France; Université Paris Diderot, Sorbonne Paris Cité, Paris, France; CNRS URA3012, Paris, France; Institut Pasteur, Unité de Mycologie Moléculaire, Centre National de Référence Mycoses Invasives et Antifongiques, Paris, France.

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April 2016

Muscle diffusion of liposomal amphotericin B and posaconazole in critically ill burn patients receiving continuous hemodialysis.

Intensive Care Med 2015 May 24;41(5):948-9. Epub 2015 Mar 24.

Department of Anesthesiology and Critical Care and Burn Unit, Hôpitaux universitaires St-Louis-Lariboisière, Groupe Hospitalier St-Louis-Lariboisière, AP-HP, 75475, Paris, France.

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May 2015

Utility of adding Pneumocystis jirovecii DNA detection in nasopharyngeal aspirates in immunocompromised adult patients with febrile pneumonia.

Med Mycol 2015 Apr 30;53(3):241-7. Epub 2014 Dec 30.

Laboratoire de Parasitologie et de Mycologie, APHP, Hôpital Saint Louis Université Paris Diderot, Sorbonne Paris Cité CNRS URA3012 Institut Pasteur, Unité de Mycologie Moléculaire, Centre National de Référence Mycoses Invasives et Antifongiques, Paris, France

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April 2015

Mucormycosis: a new concern in the transplant ward?

Curr Opin Hematol 2014 Nov;21(6):482-90

aHematology Department, Henri Mondor Teaching Hospital, Assistance Publique-Hôpitaux de Paris (AP-HP) bParis-Est Créteil University (UPEC), Créteil cParasitology-Mycology Laboratory, Groupe hospitalier Lariboisière Saint-Louis Fernand Widal dUniversité Paris-Diderot, Sorbonne Paris Cité eInstitut Pasteur, Unité de mycologie moléculaire, CNRS URA3012, Centre National de Référence Mycoses invasives et Antifongiques, Paris, France.

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November 2014

Azole preexposure affects the Aspergillus fumigatus population in patients.

Antimicrob Agents Chemother 2012 Sep 18;56(9):4948-50. Epub 2012 Jun 18.

Institut Pasteur, Unité de mycologie moléculaire, Paris, France.

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September 2012

In vitro combination of anidulafungin and voriconazole against intrinsically azole-susceptible and -resistant Aspergillus spp.

Antimicrob Agents Chemother 2012 Aug 21;56(8):4500-3. Epub 2012 May 21.

Université Paris-Descartes, Faculté de Médecine, APHP, Hôpital Européen Georges Pompidou, Unité de Parasitologie-Mycologie, Service de Microbiologie, Paris, France.

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August 2012

Low prevalence of resistance to azoles in Aspergillus fumigatus in a French cohort of patients treated for haematological malignancies.

J Antimicrob Chemother 2011 Feb 5;66(2):371-4. Epub 2010 Dec 5.

Laboratoire de Parasitologie-Mycologie, Groupe hospitalier Chenevier-Mondor, Assitance Publique-Hôpitaux de Paris, Créteil, France.

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February 2011

Microsporum praecox: molecular identification of a new case and review of the literature.

Mycopathologia 2011 Jan 25;171(1):61-5. Epub 2010 Jul 25.

Laboratoire de Parasitologie-Mycologie, Hôpital Henri Mondor, (AP-HP) Créteil, Université Paris Est, 51 avenue du Maréchal De Lattre de Tassigny, 94010, Créteil, France.

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January 2011

Real-time identification of bacteria and Candida species in positive blood culture broths by matrix-assisted laser desorption ionization-time of flight mass spectrometry.

J Clin Microbiol 2010 May 17;48(5):1542-8. Epub 2010 Mar 17.

Laboratoire de Microbiologie, Assistance Publique-Hôpitaux de Paris, Hôpital Necker-Enfants Malades, and Université René Descartes Paris 5, Faculté de Médecine, 149 Rue de Sèvres, 75015 Paris, France.

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May 2010