Alexandra Zhernakova

Alexandra Zhernakova

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Alexandra Zhernakova

Publications by authors named "Alexandra Zhernakova"

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Global phylogeography and ancient evolution of the widespread human gut virus crAssphage.

Authors:
Robert A Edwards Alejandro A Vega Holly M Norman Maria Ohaeri Kyle Levi Elizabeth A Dinsdale Ondrej Cinek Ramy K Aziz Katelyn McNair Jeremy J Barr Kyle Bibby Stan J J Brouns Adrian Cazares Patrick A de Jonge Christelle Desnues Samuel L Díaz Muñoz Peter C Fineran Alexander Kurilshikov Rob Lavigne Karla Mazankova David T McCarthy Franklin L Nobrega Alejandro Reyes Muñoz German Tapia Nicole Trefault Alexander V Tyakht Pablo Vinuesa Jeroen Wagemans Alexandra Zhernakova Frank M Aarestrup Gunduz Ahmadov Abeer Alassaf Josefa Anton Abigail Asangba Emma K Billings Vito Adrian Cantu Jane M Carlton Daniel Cazares Gyu-Sung Cho Tess Condeff Pilar Cortés Mike Cranfield Daniel A Cuevas Rodrigo De la Iglesia Przemyslaw Decewicz Michael P Doane Nathaniel J Dominy Lukasz Dziewit Bashir Mukhtar Elwasila A Murat Eren Charles Franz Jingyuan Fu Cristina Garcia-Aljaro Elodie Ghedin Kristen M Gulino John M Haggerty Steven R Head Rene S Hendriksen Colin Hill Heikki Hyöty Elena N Ilina Mitchell T Irwin Thomas C Jeffries Juan Jofre Randall E Junge Scott T Kelley Mohammadali Khan Mirzaei Martin Kowalewski Deepak Kumaresan Steven R Leigh David Lipson Eugenia S Lisitsyna Montserrat Llagostera Julia M Maritz Linsey C Marr Angela McCann Shahar Molshanski-Mor Silvia Monteiro Benjamin Moreira-Grez Megan Morris Lawrence Mugisha Maite Muniesa Horst Neve Nam-Phuong Nguyen Olivia D Nigro Anders S Nilsson Taylor O'Connell Rasha Odeh Andrew Oliver Mariana Piuri Aaron J Prussin Ii Udi Qimron Zhe-Xue Quan Petra Rainetova Adán Ramírez-Rojas Raul Raya Kim Reasor Gillian A O Rice Alessandro Rossi Ricardo Santos John Shimashita Elyse N Stachler Lars C Stene Ronan Strain Rebecca Stumpf Pedro J Torres Alan Twaddle MaryAnn Ugochi Ibekwe Nicolás Villagra Stephen Wandro Bryan White Andy Whiteley Katrine L Whiteson Cisca Wijmenga Maria M Zambrano Henrike Zschach Bas E Dutilh

Nat Microbiol 2019 Jul 8. Epub 2019 Jul 8.

Theoretical Biology and Bioinformatics, Science4Life, Utrecht University, Utrecht, The Netherlands.

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http://dx.doi.org/10.1038/s41564-019-0494-6DOI Listing
July 2019

The neuroactive potential of the human gut microbiota in quality of life and depression.

Nat Microbiol 2019 04 4;4(4):623-632. Epub 2019 Feb 4.

Department of Microbiology and Immunology, Rega Institute for Medical Research, KU Leuven-University of Leuven, Leuven, Belgium.

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http://dx.doi.org/10.1038/s41564-018-0337-xDOI Listing
April 2019

Structural variation in the gut microbiome associates with host health.

Nature 2019 04 27;568(7750):43-48. Epub 2019 Mar 27.

Department of Computer Science and Applied Mathematics, Weizmann Institute of Science, Rehovot, Israel.

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http://www.nature.com/articles/s41586-019-1065-y
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http://dx.doi.org/10.1038/s41586-019-1065-yDOI Listing
April 2019

Anti-inflammatory Gut Microbial Pathways Are Decreased During Crohn's Disease Exacerbations.

J Crohns Colitis 2019 Apr 10. Epub 2019 Apr 10.

University Medical Center Groningen, Department of Gastroenterology and Hepatology, Groningen, The Netherlands.

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http://dx.doi.org/10.1093/ecco-jcc/jjz077DOI Listing
April 2019

Shared gut, but distinct oral microbiota composition in primary Sjögren's syndrome and systemic lupus erythematosus.

J Autoimmun 2019 Feb 9;97:77-87. Epub 2018 Nov 9.

Department of Rheumatology & Clinical Immunology, University of Groningen, University Medical Center Groningen, PO Box 30.001, 9700 RB, Groningen, The Netherlands.

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http://dx.doi.org/10.1016/j.jaut.2018.10.009DOI Listing
February 2019

Dysbiosis of the buccal mucosa microbiome in primary Sjögren's syndrome patients.

Rheumatology (Oxford) 2018 Dec;57(12):2225-2234

Department of Oral and Maxillofacial Surgery, University Medical Center Groningen, Groningen, The Netherlands.

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http://dx.doi.org/10.1093/rheumatology/key215DOI Listing
December 2018

Reduced salivary secretion contributes more to changes in the oral microbiome of patients with primary Sjögren's syndrome than underlying disease.

Ann Rheum Dis 2018 Oct 23;77(10):1542-1544. Epub 2018 Mar 23.

Department of Oral and Maxillofacial Surgery, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.

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http://dx.doi.org/10.1136/annrheumdis-2018-213026DOI Listing
October 2018

A system biology perspective on environment-host-microbe interactions.

Hum Mol Genet 2018 08;27(R2):R187-R194

Department of Genetics, University Medical Center Groningen, University of Groningen, Groningen, RB, The Netherlands.

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http://dx.doi.org/10.1093/hmg/ddy137DOI Listing
August 2018

Female-Specific Association Between Variants on Chromosome 9 and Self-Reported Diagnosis of Irritable Bowel Syndrome.

Gastroenterology 2018 07 5;155(1):168-179. Epub 2018 Apr 5.

Unit of Gastrointestinal Genetics, Department of Gastrointestinal and Liver Diseases, Biodonostia Health Research Institute, San Sebastián, Spain; Center for Molecular Medicine, Karolinska Institutet, Stockholm, Sweden; Unit of Clinical Epidemiology, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden; Ikerbasque, Basque Science Foundation, Bilbao, Spain. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00165085183040
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http://dx.doi.org/10.1053/j.gastro.2018.03.064DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6035117PMC
July 2018

Pharmacomicrobiomics: a novel route towards personalized medicine?

Protein Cell 2018 05 28;9(5):432-445. Epub 2018 Apr 28.

Departments of Genetics, University Medical Center Groningen, PO Box 30001, 9700 RB, Groningen, The Netherlands.

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http://dx.doi.org/10.1007/s13238-018-0547-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5960471PMC
May 2018

The importance of cohort studies in the post-GWAS era.

Nat Genet 2018 03 6;50(3):322-328. Epub 2018 Mar 6.

Department of Genetics, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands.

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http://dx.doi.org/10.1038/s41588-018-0066-3DOI Listing
March 2018

Host Genetics and Gut Microbiome: Challenges and Perspectives.

Trends Immunol 2017 09 29;38(9):633-647. Epub 2017 Jun 29.

University of Groningen, University Medical Center Groningen, Department of Genetics, P.O. Box 30001, 9700 RB Groningen, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.it.2017.06.003DOI Listing
September 2017

The influence of proton pump inhibitors and other commonly used medication on the gut microbiota.

Gut Microbes 2017 07 24;8(4):351-358. Epub 2017 Jan 24.

a University of Groningen and University Medical Center Groningen , Department of Gastroenterology and Hepatology , Groningen , the Netherlands.

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http://dx.doi.org/10.1080/19490976.2017.1284732DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5570416PMC
July 2017

The MHC locus and genetic susceptibility to autoimmune and infectious diseases.

Genome Biol 2017 04 27;18(1):76. Epub 2017 Apr 27.

Department of Genetics, University of Groningen, University Medical Center Groningen, PO Box 30001, 9700 RB, Groningen, The Netherlands.

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http://dx.doi.org/10.1186/s13059-017-1207-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5406920PMC
April 2017

Epigenome-wide association study of body mass index, and the adverse outcomes of adiposity.

Authors:
Simone Wahl Alexander Drong Benjamin Lehne Marie Loh William R Scott Sonja Kunze Pei-Chien Tsai Janina S Ried Weihua Zhang Youwen Yang Sili Tan Giovanni Fiorito Lude Franke Simonetta Guarrera Silva Kasela Jennifer Kriebel Rebecca C Richmond Marco Adamo Uzma Afzal Mika Ala-Korpela Benedetta Albetti Ole Ammerpohl Jane F Apperley Marian Beekman Pier Alberto Bertazzi S Lucas Black Christine Blancher Marc-Jan Bonder Mario Brosch Maren Carstensen-Kirberg Anton J M de Craen Simon de Lusignan Abbas Dehghan Mohamed Elkalaawy Krista Fischer Oscar H Franco Tom R Gaunt Jochen Hampe Majid Hashemi Aaron Isaacs Andrew Jenkinson Sujeet Jha Norihiro Kato Vittorio Krogh Michael Laffan Christa Meisinger Thomas Meitinger Zuan Yu Mok Valeria Motta Hong Kiat Ng Zacharoula Nikolakopoulou Georgios Nteliopoulos Salvatore Panico Natalia Pervjakova Holger Prokisch Wolfgang Rathmann Michael Roden Federica Rota Michelle Ann Rozario Johanna K Sandling Clemens Schafmayer Katharina Schramm Reiner Siebert P Eline Slagboom Pasi Soininen Lisette Stolk Konstantin Strauch E-Shyong Tai Letizia Tarantini Barbara Thorand Ettje F Tigchelaar Rosario Tumino Andre G Uitterlinden Cornelia van Duijn Joyce B J van Meurs Paolo Vineis Ananda Rajitha Wickremasinghe Cisca Wijmenga Tsun-Po Yang Wei Yuan Alexandra Zhernakova Rachel L Batterham George Davey Smith Panos Deloukas Bastiaan T Heijmans Christian Herder Albert Hofman Cecilia M Lindgren Lili Milani Pim van der Harst Annette Peters Thomas Illig Caroline L Relton Melanie Waldenberger Marjo-Riitta Järvelin Valentina Bollati Richie Soong Tim D Spector James Scott Mark I McCarthy Paul Elliott Jordana T Bell Giuseppe Matullo Christian Gieger Jaspal S Kooner Harald Grallert John C Chambers

Nature 2017 01 21;541(7635):81-86. Epub 2016 Dec 21.

Department of Epidemiology and Biostatistics, MRC-PHE Centre for Environment and Health, School of Public Health, Imperial College London, London W2 1PG, UK.

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http://dx.doi.org/10.1038/nature20784DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5570525PMC
January 2017

Linking the Human Gut Microbiome to Inflammatory Cytokine Production Capacity.

Cell 2016 11;167(4):1125-1136.e8

The Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA; Center for Computational and Integrative Biology, Massachusetts General Hospital, Boston, MA 02114, USA; Gastrointestinal Unit and Center for the Study of Inflammatory Bowel Disease, Massachusetts General Hospital, Boston, MA 02114, USA; Center for Microbiome Informatics and Therapeutics, Massachusetts Institute of Technology, Cambridge, MA 02139, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2016.10.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5131922PMC
November 2016

The influence of a short-term gluten-free diet on the human gut microbiome.

Genome Med 2016 Apr 21;8(1):45. Epub 2016 Apr 21.

Department of Genetics, University of Groningen, University Medical Centre Groningen, Groningen, The Netherlands.

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http://dx.doi.org/10.1186/s13073-016-0295-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4841035PMC
April 2016

Population-level analysis of gut microbiome variation.

Science 2016 Apr 28;352(6285):560-4. Epub 2016 Apr 28.

KU Leuven-University of Leuven, Department of Microbiology and Immunology, Leuven, Belgium. VIB, Center for the Biology of Disease, Leuven, Belgium. Vrije Universiteit Brussel, Faculty of Sciences and Bioengineering Sciences, Microbiology Unit, Brussels, Belgium.

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http://dx.doi.org/10.1126/science.aad3503DOI Listing
April 2016

TYK2 protein-coding variants protect against rheumatoid arthritis and autoimmunity, with no evidence of major pleiotropic effects on non-autoimmune complex traits.

PLoS One 2015 7;10(4):e0122271. Epub 2015 Apr 7.

Division of Rheumatology, Immunology, and Allergy, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America; Division of Genetics, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America; Program in Medical and Population Genetics, Broad Institute, Cambridge, Massachusetts, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0122271PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4388675PMC
March 2016

The Gut Microbiome Contributes to a Substantial Proportion of the Variation in Blood Lipids.

Circ Res 2015 Oct 10;117(9):817-24. Epub 2015 Sep 10.

From the Department of Pediatrics (J.F., E.B., M.H.H.), Department of Genetics (J.F., M.J.B., M.C.C., E.F.T., A.M., J.A.M.D., J.M., L.F., C.W., A.Z.), and Department of Gastroenterology and Hepatology (F.I., R.K.W.), University of Groningen, University Medical Center Groningen, Groningen, The Netherlands; Top Institute Food and Nutrition, Wageningen, The Netherlands (E.F.T., J.A.M.D., A.Z.); Department of Immunology, Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, Krakow, Poland (J.M.); Broad Institute of MIT and Harvard, Cambridge, MA (T.W.P., R.J.X., D.G.); and Gastrointestinal Unit and Center for the Study of Inflammatory Bowel Disease (R.J.X.) and Center for Computational and Integrative Biology (R.J.X.), Massachusetts General Hospital and Harvard Medical School, Boston.

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http://dx.doi.org/10.1161/CIRCRESAHA.115.306807DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4596485PMC
October 2015

The transcriptional landscape of age in human peripheral blood.

Authors:
Marjolein J Peters Roby Joehanes Luke C Pilling Claudia Schurmann Karen N Conneely Joseph Powell Eva Reinmaa George L Sutphin Alexandra Zhernakova Katharina Schramm Yana A Wilson Sayuko Kobes Taru Tukiainen Yolande F Ramos Harald H H Göring Myriam Fornage Yongmei Liu Sina A Gharib Barbara E Stranger Philip L De Jager Abraham Aviv Daniel Levy Joanne M Murabito Peter J Munson Tianxiao Huan Albert Hofman André G Uitterlinden Fernando Rivadeneira Jeroen van Rooij Lisette Stolk Linda Broer Michael M P J Verbiest Mila Jhamai Pascal Arp Andres Metspalu Liina Tserel Lili Milani Nilesh J Samani Pärt Peterson Silva Kasela Veryan Codd Annette Peters Cavin K Ward-Caviness Christian Herder Melanie Waldenberger Michael Roden Paula Singmann Sonja Zeilinger Thomas Illig Georg Homuth Hans-Jörgen Grabe Henry Völzke Leif Steil Thomas Kocher Anna Murray David Melzer Hanieh Yaghootkar Stefania Bandinelli Eric K Moses Jack W Kent Joanne E Curran Matthew P Johnson Sarah Williams-Blangero Harm-Jan Westra Allan F McRae Jennifer A Smith Sharon L R Kardia Iiris Hovatta Markus Perola Samuli Ripatti Veikko Salomaa Anjali K Henders Nicholas G Martin Alicia K Smith Divya Mehta Elisabeth B Binder K Maria Nylocks Elizabeth M Kennedy Torsten Klengel Jingzhong Ding Astrid M Suchy-Dicey Daniel A Enquobahrie Jennifer Brody Jerome I Rotter Yii-Der I Chen Jeanine Houwing-Duistermaat Margreet Kloppenburg P Eline Slagboom Quinta Helmer Wouter den Hollander Shannon Bean Towfique Raj Noman Bakhshi Qiao Ping Wang Lisa J Oyston Bruce M Psaty Russell P Tracy Grant W Montgomery Stephen T Turner John Blangero Ingrid Meulenbelt Kerry J Ressler Jian Yang Lude Franke Johannes Kettunen Peter M Visscher G Gregory Neely Ron Korstanje Robert L Hanson Holger Prokisch Luigi Ferrucci Tonu Esko Alexander Teumer Joyce B J van Meurs Andrew D Johnson

Nat Commun 2015 Oct 22;6:8570. Epub 2015 Oct 22.

The National Heart, Lung, and Blood Institute's and Boston University's Framingham Heart Study, Framingham, Massachusetts 01702, USA.

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http://dx.doi.org/10.1038/ncomms9570DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4639797PMC
October 2015

Genetic Factors for the Severity of ACPA-negative Rheumatoid Arthritis in 2 Cohorts of Early Disease: A Genome-wide Study.

J Rheumatol 2015 Aug 15;42(8):1383-91. Epub 2015 Jun 15.

From the Department of Rheumatology, and the Department of Medical Statistics, Leiden University Medical Center, Leiden, the Netherlands; the Section of Rheumatology at the Institution of Clinical Science, Lund University, Skåne University Hospital, Lund, Sweden, for the BARFOT study group; the Department of Genetics, University Medical Center Groningen and University of Groningen, Groningen, The Netherlands; Center of Experimental Rheumatology, University Hospital Zurich, Schlieren, Switzerland; the Department of Medical Genetics, University Medical Center Utrecht, Utrecht, The Netherlands.D.P. de Rooy, LLM, MD, PhD, Department of Rheumatology, Leiden University Medical Center; R. Tsonaka, PhD, Department of Medical Statistics, Leiden University Medical Center; M.L. Andersson, BMS, PhD; K. Forslind, Associate Professor, Senior Consultant, Section of Rheumatology at the Institution of Clinical Science, Lund University, Skåne University Hospital, for the BARFOT study group; A. Zhernakova, MD, PhD, Department of Rheumatology, Leiden University Medical Center, and Department of Genetics, University Medical Center Groningen and University of Groningen; M. Frank-Bertoncelj, MD, PhD, Center of Experimental Rheumatology, University Hospital Zurich; C.G. de Kovel, PhD; B.P. Koeleman, PhD, Department of Medical Genetics, University Medical Center Utrecht; D.M. van der Heijde, MD, PhD; T.W. Huizinga, MD, PhD; R.E. Toes, PhD, Department of Rheumatology, Leiden University Medical Center; J.J. Houwing-Duistermaat, PhD, PD, Department of Medical Statistics, Leiden University Medical Center; C. Ospelt, MD, PhD, Center of Experimental Rheumatology, University Hospital Zurich; B. Svensson, MD, PhD, Section of Rheumatology at the Institution of Clinical Science, Lund University, Skåne University Hospital, for the BARFOT study group; A.H. van der Helm-van Mil, MD, PhD, Department of Rheumatology, Leiden University Medical Center.

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http://dx.doi.org/10.3899/jrheum.140741DOI Listing
August 2015

Improving Phenotypic Prediction by Combining Genetic and Epigenetic Associations.

Am J Hum Genet 2015 Jul 25;97(1):75-85. Epub 2015 Jun 25.

Queensland Brain Institute, University of Queensland, Brisbane 4072, Australia; University of Queensland Diamantina Institute, Translational Research Institute, University of Queensland, Brisbane, QLD 4072, Australia; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh EH8 9JZ, UK. Electronic address:

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http://dx.doi.org/10.1016/j.ajhg.2015.05.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4572498PMC
July 2015

Fine mapping in the MHC region accounts for 18% additional genetic risk for celiac disease.

Nat Genet 2015 Jun 20;47(6):577-8. Epub 2015 Apr 20.

1] Department of Medical Genetics, Center for Molecular Medicine, University Medical Center Utrecht, Utrecht, the Netherlands. [2] Department of Epidemiology, Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, the Netherlands.

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http://www.nature.com/articles/ng.3268
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http://dx.doi.org/10.1038/ng.3268DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4449296PMC
June 2015

The genetics of East African populations: a Nilo-Saharan component in the African genetic landscape.

Sci Rep 2015 May 28;5:9996. Epub 2015 May 28.

Institut de Biologia Evolutiva (UPF-CSIC), Departament de Ciències Experimentals i de la Salut, Universitat Pompeu Fabra, Barcelona, Catalonia, Spain.

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http://dx.doi.org/10.1038/srep09996DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4446898PMC
May 2015

Evaluation of European coeliac disease risk variants in a north Indian population.

Eur J Hum Genet 2015 Apr 23;23(4):530-5. Epub 2014 Jul 23.

Department of Genetics, University of Groningen, University Medical Hospital Groningen, Groningen, The Netherlands.

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http://dx.doi.org/10.1038/ejhg.2014.137DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4666579PMC
April 2015

Association analysis of genetic variants in the myosin IXB gene in acute pancreatitis.

PLoS One 2013 30;8(12):e85870. Epub 2013 Dec 30.

Complex Genetics Group, Department of Medical Genetics, University Medical Center Utrecht, Utrecht, the Netherlands ; Department of Genetics, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0085870PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3875581PMC
February 2015

Fine mapping seronegative and seropositive rheumatoid arthritis to shared and distinct HLA alleles by adjusting for the effects of heterogeneity.

Am J Hum Genet 2014 Apr 20;94(4):522-32. Epub 2014 Mar 20.

Division of Genetics, Brigham & Women's Hospital and Harvard Medical School, Boston, MA 02115, USA; Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA; Partners HealthCare Center for Personalized Genetic Medicine, Boston, MA 02115, USA; Division of Rheumatology, Immunology, and Allergy, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, 02115, USA; Arthritis Research UK Epidemiology Unit, Musculoskeletal Research Group, University of Manchester, Manchester Academic Health Sciences Centre, Manchester M13 9PT, UK. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00029297140007
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http://dx.doi.org/10.1016/j.ajhg.2014.02.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3980428PMC
April 2014

Genetics of rheumatoid arthritis contributes to biology and drug discovery.

Nature 2014 Feb 25;506(7488):376-81. Epub 2013 Dec 25.

1] Division of Rheumatology, Immunology, and Allergy, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA. [2] Division of Genetics, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA. [3] Program in Medical and Population Genetics, Broad Institute, Cambridge, Massachusetts 02142, USA.

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http://dx.doi.org/10.1038/nature12873DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3944098PMC
February 2014

Immunochip analysis identifies multiple susceptibility loci for systemic sclerosis.

Am J Hum Genet 2014 Jan;94(1):47-61

Instituto de Parasitología y Biomedicina López-Neyra, Consejo Superior de Investigaciones Científicas, Granada 18016, Spain.

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http://eprints.gla.ac.uk/104672/1/104672.pdf
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http://linkinghub.elsevier.com/retrieve/pii/S000292971300571
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http://dx.doi.org/10.1016/j.ajhg.2013.12.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3882906PMC
January 2014

Clinical implications of shared genetics and pathogenesis in autoimmune diseases.

Nat Rev Endocrinol 2013 Nov 20;9(11):646-59. Epub 2013 Aug 20.

University of Groningen, University Medical Centre Groningen, Department of Genetics, PO Box 30001, 9700 RB Groningen, Netherlands.

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http://dx.doi.org/10.1038/nrendo.2013.161DOI Listing
November 2013

Haplotype-based analysis of ulcerative colitis risk loci identifies both IL2 and IL21 as susceptibility genes in Han Chinese.

Inflamm Bowel Dis 2011 Dec 6;17(12):2472-9. Epub 2011 Jun 6.

Department of Gastroenterology, Peking Union Medical College Hospital, Chinese Academy of Medical Science and Peking Union Medical College, Beijing, P.R. China.

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http://dx.doi.org/10.1002/ibd.21652DOI Listing
December 2011

Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci.

Nat Genet 2010 Jun 9;42(6):508-14. Epub 2010 May 9.

Division of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1038/ng.582DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4243840PMC
June 2010

Multiple common variants for celiac disease influencing immune gene expression.

Nat Genet 2010 Apr 28;42(4):295-302. Epub 2010 Feb 28.

Blizard Institute of Cell and Molecular Science, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.

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http://dx.doi.org/10.1038/ng.543DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2847618PMC
April 2010

Analysis of HLA and non-HLA alleles can identify individuals at high risk for celiac disease.

Gastroenterology 2009 Sep 18;137(3):834-40, 840.e1-3. Epub 2009 May 18.

Department of Genetics, University Medical Centre of Groningen, University of Groningen, Groningen, The Netherlands.

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http://dx.doi.org/10.1053/j.gastro.2009.05.040DOI Listing
September 2009

Detecting shared pathogenesis from the shared genetics of immune-related diseases.

Nat Rev Genet 2009 Jan;10(1):43-55

Department of Medical Genetics, University Medical Centre Utrecht, Utrecht 3508 AB, the Netherlands.

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http://dx.doi.org/10.1038/nrg2489DOI Listing
January 2009

ATG16L1 and IL23R are associated with inflammatory bowel diseases but not with celiac disease in the Netherlands.

Am J Gastroenterol 2008 Mar 28;103(3):621-7. Epub 2007 Nov 28.

Department of Gastroenterology and Hepatology, University Medical Center Groningen, The Netherlands.

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http://dx.doi.org/10.1111/j.1572-0241.2007.01660.xDOI Listing
March 2008

The MYO9B gene is a strong risk factor for developing refractory celiac disease.

Clin Gastroenterol Hepatol 2007 Dec 29;5(12):1399-405, 1405.e1-2. Epub 2007 Oct 29.

Department of Pediatric Gastroenterology, University Medical Centre Utrecht, Utrecht, The Netherlands.

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http://dx.doi.org/10.1016/j.cgh.2007.08.018DOI Listing
December 2007