Alexandra Segref

Alexandra Segref

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Alexandra Segref

Alexandra Segref

Publications by authors named "Alexandra Segref"

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16Publications

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Reversible 26S proteasome disassembly upon mitochondrial stress.

Cell Rep 2014 Jun 22;7(5):1371-1380. Epub 2014 May 22.

Department of Biology, Technion-Israel Institute of Technology, Haifa 32000, Israel. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2014.04.030DOI Listing
June 2014

Pathogenesis of human mitochondrial diseases is modulated by reduced activity of the ubiquitin/proteasome system.

Cell Metab 2014 Apr;19(4):642-52

Institute for Genetics and Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, Zülpicher Strasse 47a, 50674 Cologne, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.cmet.2014.01.016DOI Listing
April 2014

DNA damage in germ cells induces an innate immune response that triggers systemic stress resistance.

Nature 2013 Sep 25;501(7467):416-20. Epub 2013 Aug 25.

Cologne Excellence Cluster for Cellular Stress Responses in Aging-Associated Diseases, Institute for Genetics, University of Cologne, Zülpicher Strasse 47a, 50674 Cologne, Germany.

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http://dx.doi.org/10.1038/nature12452DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4120807PMC
September 2013

A novel interaction between aging and ER overload in a protein conformational dementia.

Genetics 2013 Mar 18;193(3):865-76. Epub 2013 Jan 18.

Institute of Neuropathology, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.

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http://dx.doi.org/10.1534/genetics.112.149088DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3584003PMC
March 2013

Analysis of ubiquitin-dependent proteolysis in Caenorhabditis elegans.

Methods Mol Biol 2012 ;832:531-44

Institute for Genetics and Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, Cologne, Germany.

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http://dx.doi.org/10.1007/978-1-61779-474-2_38DOI Listing
July 2012

A screenable in vivo assay to study proteostasis networks in Caenorhabditis elegans.

Genetics 2011 Apr 1;187(4):1235-40. Epub 2011 Feb 1.

Institute for Genetics and Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases, University of Cologne, 50674 Cologne, Germany.

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http://dx.doi.org/10.1534/genetics.111.126797DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3070531PMC
April 2011

The Machado-Joseph disease deubiquitylase ATX-3 couples longevity and proteostasis.

Nat Cell Biol 2011 Mar 13;13(3):273-81. Epub 2011 Feb 13.

Centre for Molecular Neurobiology (ZMNH), University of Hamburg, Falkenried 94, 20251 Hamburg, Germany.

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http://dx.doi.org/10.1038/ncb2200DOI Listing
March 2011

Fate specification and tissue-specific cell cycle control of the Caenorhabditis elegans intestine.

Mol Biol Cell 2010 Mar 6;21(5):725-38. Epub 2010 Jan 6.

Division of Molecular Genetics, Institute of Biomedical and Life Sciences, University of Glasgow, Glasgow, United Kingdom.

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http://dx.doi.org/10.1091/mbc.e09-04-0268DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2828960PMC
March 2010

Think locally: control of ubiquitin-dependent protein degradation in neurons.

EMBO Rep 2009 Jan 12;10(1):44-50. Epub 2008 Dec 12.

Centre for Molecular Neurobiology, ZMNH, University of Hamburg, Hamburg, Germany.

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http://dx.doi.org/10.1038/embor.2008.229DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2613211PMC
January 2009

Co-crystallization of the human nuclear cap-binding complex with a m7GpppG cap analogue using protein engineering.

Acta Crystallogr D Biol Crystallogr 2002 Dec 23;58(Pt 12):2194-7. Epub 2002 Nov 23.

European Molecular Biology Laboratory, Grenoble Outstation, c/o ILL, BP 181, F-38042 Grenoble CEDEX 9, France.

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http://dx.doi.org/10.1107/s0907444902015445DOI Listing
December 2002

Large-scale induced fit recognition of an m(7)GpppG cap analogue by the human nuclear cap-binding complex.

EMBO J 2002 Oct;21(20):5548-57

European Molecular Biology Laboratory, Grenoble Outstation, c/o ILL, BP 181, F-38042 Grenoble cedex 9, France.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC129070PMC
http://dx.doi.org/10.1093/emboj/cdf538DOI Listing
October 2002

Identity elements used in export of mRNAs.

Mol Cell 2002 Mar;9(3):659-71

The Institute for Virus Research, Laboratory of Biochemistry, Kyoto University, Sakyo-ku, Kyoto 606-8507, Japan.

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http://dx.doi.org/10.1016/s1097-2765(02)00454-9DOI Listing
March 2002