Alexandra Nica

Alexandra Nica

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Alexandra Nica

Alexandra Nica

Publications by authors named "Alexandra Nica"

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Estimating the causal tissues for complex traits and diseases.

Nat Genet 2017 Dec 23;49(12):1676-1683. Epub 2017 Oct 23.

Department of Genetic Medicine and Development, University of Geneva Medical School, Geneva, Switzerland.

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http://dx.doi.org/10.1038/ng.3981DOI Listing
December 2017

Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility.

Authors:
Anubha Mahajan Min Jin Go Weihua Zhang Jennifer E Below Kyle J Gaulton Teresa Ferreira Momoko Horikoshi Andrew D Johnson Maggie C Y Ng Inga Prokopenko Danish Saleheen Xu Wang Eleftheria Zeggini Goncalo R Abecasis Linda S Adair Peter Almgren Mustafa Atalay Tin Aung Damiano Baldassarre Beverley Balkau Yuqian Bao Anthony H Barnett Ines Barroso Abdul Basit Latonya F Been John Beilby Graeme I Bell Rafn Benediktsson Richard N Bergman Bernhard O Boehm Eric Boerwinkle Lori L Bonnycastle Noël Burtt Qiuyin Cai Harry Campbell Jason Carey Stephane Cauchi Mark Caulfield Juliana C N Chan Li-Ching Chang Tien-Jyun Chang Yi-Cheng Chang Guillaume Charpentier Chien-Hsiun Chen Han Chen Yuan-Tsong Chen Kee-Seng Chia Manickam Chidambaram Peter S Chines Nam H Cho Young Min Cho Lee-Ming Chuang Francis S Collins Marylin C Cornelis David J Couper Andrew T Crenshaw Rob M van Dam John Danesh Debashish Das Ulf de Faire George Dedoussis Panos Deloukas Antigone S Dimas Christian Dina Alex S Doney Peter J Donnelly Mozhgan Dorkhan Cornelia van Duijn Josée Dupuis Sarah Edkins Paul Elliott Valur Emilsson Raimund Erbel Johan G Eriksson Jorge Escobedo Tonu Esko Elodie Eury Jose C Florez Pierre Fontanillas Nita G Forouhi Tom Forsen Caroline Fox Ross M Fraser Timothy M Frayling Philippe Froguel Philippe Frossard Yutang Gao Karl Gertow Christian Gieger Bruna Gigante Harald Grallert George B Grant Leif C Grrop Chrisropher J Groves Elin Grundberg Candace Guiducci Anders Hamsten Bok-Ghee Han Kazuo Hara Neelam Hassanali Andrew T Hattersley Caroline Hayward Asa K Hedman Christian Herder Albert Hofman Oddgeir L Holmen Kees Hovingh Astradur B Hreidarsson Cheng Hu Frank B Hu Jennie Hui Steve E Humphries Sarah E Hunt David J Hunter Kristian Hveem Zafar I Hydrie Hiroshi Ikegami Thomas Illig Erik Ingelsson Muhammed Islam Bo Isomaa Anne U Jackson Tazeen Jafar Alan James Weiping Jia Karl-Heinz Jöckel Anna Jonsson Jeremy B M Jowett Takashi Kadowaki Hyun Min Kang Stavroula Kanoni Wen Hong L Kao Sekar Kathiresan Norihiro Kato Prasad Katulanda Kirkka M Keinanen-Kiukaanniemi Ann M Kelly Hassan Khan Kay-Tee Khaw Chiea-Chuen Khor Hyung-Lae Kim Sangsoo Kim Young Jin Kim Leena Kinnunen Norman Klopp Augustine Kong Eeva Korpi-Hyövälti Sudhir Kowlessur Peter Kraft Jasmina Kravic Malene M Kristensen S Krithika Ashish Kumar Jesus Kumate Johanna Kuusisto Soo Heon Kwak Markku Laakso Vasiliki Lagou Timo A Lakka Claudia Langenberg Cordelia Langford Robert Lawrence Karin Leander Jen-Mai Lee Nanette R Lee Man Li Xinzhong Li Yun Li Junbin Liang Samuel Liju Wei-Yen Lim Lars Lind Cecilia M Lindgren Eero Lindholm Ching-Ti Liu Jian Jun Liu Stéphane Lobbens Jirong Long Ruth J F Loos Wei Lu Jian'an Luan Valeriya Lyssenko Ronald C W Ma Shiro Maeda Reedik Mägi Satu Männisto David R Matthews James B Meigs Olle Melander Andres Metspalu Julia Meyer Ghazala Mirza Evelin Mihailov Susanne Moebus Viswanathan Mohan Karen L Mohlke Andrew D Morris Thomas W Mühleisen Martina Müller-Nurasyid Bill Musk Jiro Nakamura Eitaro Nakashima Pau Navarro Peng-Keat Ng Alexandra C Nica Peter M Nilsson Inger Njølstad Markus M Nöthen Keizo Ohnaka Twee Hee Ong Katharine R Owen Colin N A Palmer James S Pankow Kyong Soo Park Melissa Parkin Sonali Pechlivanis Nancy L Pedersen Leena Peltonen John R B Perry Annette Peters Janini M Pinidiyapathirage Carl G Platou Simon Potter Jackie F Price Lu Qi Venkatesan Radha Loukianos Rallidis Asif Rasheed Wolfgang Rathman Rainer Rauramaa Soumya Raychaudhuri N William Rayner Simon D Rees Emil Rehnberg Samuli Ripatti Neil Robertson Michael Roden Elizabeth J Rossin Igor Rudan Denis Rybin Timo E Saaristo Veikko Salomaa Juha Saltevo Maria Samuel Dharambir K Sanghera Jouko Saramies James Scott Laura J Scott Robert A Scott Ayellet V Segrè Joban Sehmi Bengt Sennblad Nabi Shah Sonia Shah A Samad Shera Xiao Ou Shu Alan R Shuldiner Gunnar Sigurđsson Eric Sijbrands Angela Silveira Xueling Sim Suthesh Sivapalaratnam Kerrin S Small Wing Yee So Alena Stančáková Kari Stefansson Gerald Steinbach Valgerdur Steinthorsdottir Kathleen Stirrups Rona J Strawbridge Heather M Stringham Qi Sun Chen Suo Ann-Christine Syvänen Ryoichi Takayanagi Fumihiko Takeuchi Wan Ting Tay Tanya M Teslovich Barbara Thorand Gudmar Thorleifsson Unnur Thorsteinsdottir Emmi Tikkanen Joseph Trakalo Elena Tremoli Mieke D Trip Fuu Jen Tsai Tiinamaija Tuomi Jaakko Tuomilehto Andre G Uitterlinden Adan Valladares-Salgado Sailaja Vedantam Fabrizio Veglia Benjamin F Voight Congrong Wang Nicholas J Wareham Roman Wennauer Ananda R Wickremasinghe Tom Wilsgaard James F Wilson Steven Wiltshire Wendy Winckler Tien Yin Wong Andrew R Wood Jer-Yuarn Wu Ying Wu Ken Yamamoto Toshimasa Yamauchi Mingyu Yang Loic Yengo Mitsuhiro Yokota Robin Young Delilah Zabaneh Fan Zhang Rong Zhang Wei Zheng Paul Z Zimmet David Altshuler Donald W Bowden Yoon Shin Cho Nancy J Cox Miguel Cruz Craig L Hanis Jaspal Kooner Jong-Young Lee Mark Seielstad Yik Ying Teo Michael Boehnke Esteban J Parra Jonh C Chambers E Shyong Tai Mark I McCarthy Andrew P Morris

Nat Genet 2014 Mar 9;46(3):234-44. Epub 2014 Feb 9.

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http://dx.doi.org/10.1038/ng.2897DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3969612PMC
March 2014

Expression, phosphorylation and function of the Rab-GTPase activating protein TBC1D1 in pancreatic beta-cells.

FEBS Lett 2014 Jan 14;588(1):15-20. Epub 2013 Nov 14.

Department of Genetic Medicine and Development, University Medical Center, University of Geneva, Geneva, Switzerland.

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http://dx.doi.org/10.1016/j.febslet.2013.10.050DOI Listing
January 2014

Expression quantitative trait loci: present and future.

Philos Trans R Soc Lond B Biol Sci 2013 6;368(1620):20120362. Epub 2013 May 6.

Department of Genetic Medicine and Development, University of Geneva Medical School, Geneva 1211, Switzerland.

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http://dx.doi.org/10.1098/rstb.2012.0362DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3682727PMC
December 2013

Cell-type, allelic, and genetic signatures in the human pancreatic beta cell transcriptome.

Genome Res 2013 Sep 28;23(9):1554-62. Epub 2013 May 28.

Department of Genetic Medicine and Development, University of Geneva Medical School, Geneva 1211, Switzerland.

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http://dx.doi.org/10.1101/gr.150706.112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3759730PMC
September 2013

Genome-wide association identifies nine common variants associated with fasting proinsulin levels and provides new insights into the pathophysiology of type 2 diabetes.

Authors:
Rona J Strawbridge Josée Dupuis Inga Prokopenko Adam Barker Emma Ahlqvist Denis Rybin John R Petrie Mary E Travers Nabila Bouatia-Naji Antigone S Dimas Alexandra Nica Eleanor Wheeler Han Chen Benjamin F Voight Jalal Taneera Stavroula Kanoni John F Peden Fabiola Turrini Stefan Gustafsson Carina Zabena Peter Almgren David J P Barker Daniel Barnes Elaine M Dennison Johan G Eriksson Per Eriksson Elodie Eury Lasse Folkersen Caroline S Fox Timothy M Frayling Anuj Goel Harvest F Gu Momoko Horikoshi Bo Isomaa Anne U Jackson Karen A Jameson Eero Kajantie Julie Kerr-Conte Teemu Kuulasmaa Johanna Kuusisto Ruth J F Loos Jian'an Luan Konstantinos Makrilakis Alisa K Manning María Teresa Martínez-Larrad Narisu Narisu Maria Nastase Mannila John Ohrvik Clive Osmond Laura Pascoe Felicity Payne Avan A Sayer Bengt Sennblad Angela Silveira Alena Stancáková Kathy Stirrups Amy J Swift Ann-Christine Syvänen Tiinamaija Tuomi Ferdinand M van 't Hooft Mark Walker Michael N Weedon Weijia Xie Björn Zethelius Halit Ongen Anders Mälarstig Jemma C Hopewell Danish Saleheen John Chambers Sarah Parish John Danesh Jaspal Kooner Claes-Göran Ostenson Lars Lind Cyrus C Cooper Manuel Serrano-Ríos Ele Ferrannini Tom J Forsen Robert Clarke Maria Grazia Franzosi Udo Seedorf Hugh Watkins Philippe Froguel Paul Johnson Panos Deloukas Francis S Collins Markku Laakso Emmanouil T Dermitzakis Michael Boehnke Mark I McCarthy Nicholas J Wareham Leif Groop François Pattou Anna L Gloyn George V Dedoussis Valeriya Lyssenko James B Meigs Inês Barroso Richard M Watanabe Erik Ingelsson Claudia Langenberg Anders Hamsten Jose C Florez

Diabetes 2011 Oct 26;60(10):2624-34. Epub 2011 Aug 26.

Atherosclerosis Research Unit, Department of Medicine Solna, Karolinska Institutet, Karolinska University Hospital Solna, Stockholm, Sweden.

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http://dx.doi.org/10.2337/db11-0415DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3178302PMC
October 2011

Epistatic selection between coding and regulatory variation in human evolution and disease.

Am J Hum Genet 2011 Sep;89(3):459-63

Department of Genetic Medicine and Development, University of Geneva Medical School, Switzerland.

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http://dx.doi.org/10.1016/j.ajhg.2011.08.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3169828PMC
September 2011

Using gene expression to investigate the genetic basis of complex disorders.

Hum Mol Genet 2008 Oct;17(R2):R129-34

The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Cambridge CB10 1HH, UK.

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http://dx.doi.org/10.1093/hmg/ddn285DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2570059PMC
October 2008

Common variants near MC4R are associated with fat mass, weight and risk of obesity.

Authors:
Ruth J F Loos Cecilia M Lindgren Shengxu Li Eleanor Wheeler Jing Hua Zhao Inga Prokopenko Michael Inouye Rachel M Freathy Antony P Attwood Jacques S Beckmann Sonja I Berndt Kevin B Jacobs Stephen J Chanock Richard B Hayes Sven Bergmann Amanda J Bennett Sheila A Bingham Murielle Bochud Morris Brown Stéphane Cauchi John M Connell Cyrus Cooper George Davey Smith Ian Day Christian Dina Subhajyoti De Emmanouil T Dermitzakis Alex S F Doney Katherine S Elliott Paul Elliott David M Evans I Sadaf Farooqi Philippe Froguel Jilur Ghori Christopher J Groves Rhian Gwilliam David Hadley Alistair S Hall Andrew T Hattersley Johannes Hebebrand Iris M Heid Claudia Lamina Christian Gieger Thomas Illig Thomas Meitinger H-Erich Wichmann Blanca Herrera Anke Hinney Sarah E Hunt Marjo-Riitta Jarvelin Toby Johnson Jennifer D M Jolley Fredrik Karpe Andrew Keniry Kay-Tee Khaw Robert N Luben Massimo Mangino Jonathan Marchini Wendy L McArdle Ralph McGinnis David Meyre Patricia B Munroe Andrew D Morris Andrew R Ness Matthew J Neville Alexandra C Nica Ken K Ong Stephen O'Rahilly Katharine R Owen Colin N A Palmer Konstantinos Papadakis Simon Potter Anneli Pouta Lu Qi Joshua C Randall Nigel W Rayner Susan M Ring Manjinder S Sandhu André Scherag Matthew A Sims Kijoung Song Nicole Soranzo Elizabeth K Speliotes Holly E Syddall Sarah A Teichmann Nicholas J Timpson Jonathan H Tobias Manuela Uda Carla I Ganz Vogel Chris Wallace Dawn M Waterworth Michael N Weedon Cristen J Willer Wraight Xin Yuan Eleftheria Zeggini Joel N Hirschhorn David P Strachan Willem H Ouwehand Mark J Caulfield Nilesh J Samani Timothy M Frayling Peter Vollenweider Gerard Waeber Vincent Mooser Panos Deloukas Mark I McCarthy Nicholas J Wareham Inês Barroso Kevin B Jacobs Stephen J Chanock Richard B Hayes Claudia Lamina Christian Gieger Thomas Illig Thomas Meitinger H-Erich Wichmann Peter Kraft Susan E Hankinson David J Hunter Frank B Hu Helen N Lyon Benjamin F Voight Martin Ridderstrale Leif Groop Paul Scheet Serena Sanna Goncalo R Abecasis Giuseppe Albai Ramaiah Nagaraja David Schlessinger Anne U Jackson Jaakko Tuomilehto Francis S Collins Michael Boehnke Karen L Mohlke

Nat Genet 2008 Jun 4;40(6):768-75. Epub 2008 May 4.

MRC Epidemiology Unit, Addenbrooke's Hospital, Cambridge CB2 0QQ, UK.

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http://dx.doi.org/10.1038/ng.140DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2669167PMC
June 2008