Alexandra Martins

Alexandra Martins

UNVERIFIED PROFILE

Are you Alexandra Martins?   Register this Author

Register author
Alexandra Martins

Alexandra Martins

Publications by authors named "Alexandra Martins"

Are you Alexandra Martins?   Register this Author

65Publications

1297Reads

42Profile Views

The impact and evolution of acute-on-chronic liver failure in decompensated cirrhosis: A Portuguese single-center study.

Gastroenterol Hepatol 2019 May 14;42(5):296-303. Epub 2019 Feb 14.

Gastroenterology Department, Hospital Professor Doutor Fernando Fonseca, Amadora, Portugal.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.gastrohep.2018.11.007DOI Listing
May 2019

Biallelic Loss of Function of SORL1 in an Early Onset Alzheimer's Disease Patient.

J Alzheimers Dis 2018 ;62(2):821-831

Normandie Univ, UNIROUEN, Inserm U1245 and Rouen University Hospital, Department of Genetics and CNR-MAJ, F 76000, Normandy Center for Genomic and Personalized Medicine, Rouen, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3233/JAD-170981DOI Listing
February 2019

Transgenerational effects and recovery of microplastics exposure in model populations of the freshwater cladoceran Daphnia magna Straus.

Sci Total Environ 2018 Aug 16;631-632:421-428. Epub 2018 Mar 16.

ICBAS - Institute of Biomedical Sciences of the University of Porto, Department of Populations Study, Laboratory of Ecotoxicology (ECOTOX), Rua de Jorge Viterbo Ferreira, 228, 4050-313 Porto, Portugal; CIIMAR - Interdisciplinary Centre of Marine and Environmental Research of the University of Porto, Research Team of Ecotoxicology, Stress Ecology and Environmental Health (ECOTOX), Avenida General Norton de Matos, 4450-208 Matosinhos, Portugal. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.scitotenv.2018.03.054DOI Listing
August 2018

Toxicological interactions induced by chronic exposure to gold nanoparticles and microplastics mixtures in Daphnia magna.

Sci Total Environ 2018 Jul 13;628-629:474-483. Epub 2018 Feb 13.

ICBAS - Institute of Biomedical Sciences of Abel Salazar, University of Porto, Department of Populations Study, Laboratory of Ecotoxicology, Rua de Jorge Viterbo Ferreira, 228, 4050-313 Porto, Portugal; CIIMAR/CIMAR-LA - Interdisciplinary Centre of Marine and Environmental Research, research Group of Ecotoxicology, Stress Ecology and Environmental Health, University of Porto, Avenida General Norton de Matos, 4450-208 Matosinhos, Portugal. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.scitotenv.2018.02.081DOI Listing
July 2018

A Complex Case of Cholestasis in a Patient with ABCB4 and ABCB11 Mutations.

GE Port J Gastroenterol 2018 Jun 25;25(4):189-194. Epub 2017 Nov 25.

Gastroenterology Department, Hospital Professor Doutor Fernando Fonseca, Amadora, Portugal.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1159/000484612DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6029212PMC
June 2018

Potentially pathogenic germline CHEK2 c.319+2T>A among multiple early-onset cancer families.

Fam Cancer 2018 01;17(1):141-153

Department of Tumor Biology, Institute for Cancer Research, Oslo University Hospital, Oslo, Norway.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s10689-017-0011-0DOI Listing
January 2018

Letter to the Editor regarding the article "Prevalence of Hepatitis A Virus Antibody in Portuguese Travelers: A New Paradigm".

Acta Med Port 2017 12 29;30(12):891-892. Epub 2017 Dec 29.

Serviço de Gastrenterologia. Hospital Professor Doutor Fernando Fonseca. Amadora. Portugal.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.20344/amp.9632DOI Listing
December 2017

The albumin-bilirubin score predicting the mortality of patients with decompensated cirrhosis.

Turk J Gastroenterol 2017 11 25;28(6):533-534. Epub 2017 Oct 25.

Department of Gastroenterology, Hospital Professor Duotor Fernando Fonseca, Amadora, Portugal.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.5152/tjg.2017.17303DOI Listing
November 2017

Wilkie Syndrome behind Crohn Disease? Superior Mesenteric Artery Syndrome Mimicking and Complicating Crohn Disease of the Upper Gastrointestinal Tract.

GE Port J Gastroenterol 2017 Jan 16;24(1):50-52. Epub 2016 Nov 16.

Gastroenterology Department, Hospital Prof. Doutor Fernando Fonseca, Amadora, Portugal.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1159/000450873DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5553365PMC
January 2017

Clinical and microbiological characteristics associated with mortality in spontaneous bacterial peritonitis: a multicenter cohort study.

Eur J Gastroenterol Hepatol 2016 Oct;28(10):1216-22

aDivison of Gastroenterology, Fernando Fonseca Hospital, Amadora bDivision of Gastroenterology, Garcia Orta Hospital, Almada cDivison of Gastroenterology, Egas Moniz Hospital, Lisbon, Portugal dDivision of Gastroenterology (Liver Unit), University of Alberta Hospital, Edmonton, Alberta, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/MEG.0000000000000700DOI Listing
October 2016

Sprue-Like Enteropathy Associated with Olmesartan: An Unrecognized Emerging Drug-Induced Enteropathy?

GE Port J Gastroenterol 2016 Nov-Dec;23(6):335-336. Epub 2016 Oct 13.

Gastroenterology Department, Hospital Prof. Doutor Fernando Fonseca, Amadora, Portugal.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jpge.2016.06.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5580016PMC
October 2016

Acute Hepatitis in the DRESS Syndrome.

GE Port J Gastroenterol 2016 Nov-Dec;23(6):304-308. Epub 2016 Aug 12.

Gastroenterology Department, Hospital Prof. Doutor Fernando Fonseca, Amadora, Portugal.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jpge.2016.06.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5580171PMC
August 2016

Combined genetic and splicing analysis of BRCA1 c.[594-2A>C; 641A>G] highlights the relevance of naturally occurring in-frame transcripts for developing disease gene variant classification algorithms.

Hum Mol Genet 2016 06 23;25(11):2256-2268. Epub 2016 Mar 23.

Department of Genetics and Computational Biology, QIMR Berghofer Medical Research Institute, Brisbane, QLD 4006, Australia

View Article

Download full-text PDF

Source
http://hmg.oxfordjournals.org/content/early/2016/03/23/hmg.d
Web Search
http://www.hmg.oxfordjournals.org/lookup/doi/10.1093/hmg/ddw
Publisher Site
http://dx.doi.org/10.1093/hmg/ddw094DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5081057PMC
June 2016

Granulomatous Cheilitis Associated With Crohn's Disease.

Am J Gastroenterol 2016 04;111(4):456

Prof. Doutor Fernando Fonseca Hospital, Amadora, Portugal.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/ajg.2015.378DOI Listing
April 2016

Infidelity in Dating Relationships: Gender-Specific Correlates of Face-to-Face and Online Extradyadic Involvement.

Arch Sex Behav 2016 Jan 21;45(1):193-205. Epub 2015 Jul 21.

Faculdade de Psicologia e Ciências da Educação da Universidade de Coimbra, Rua do Colégio Novo, 3001-802, Coimbra, Portugal.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s10508-015-0576-3DOI Listing
January 2016

Exonic Splicing Mutations Are More Prevalent than Currently Estimated and Can Be Predicted by Using In Silico Tools.

PLoS Genet 2016 Jan 13;12(1):e1005756. Epub 2016 Jan 13.

Inserm U1079-IRIB, University of Rouen, Normandy Centre for Genomic and Personalized Medicine, Rouen, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1371/journal.pgen.1005756DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4711968PMC
January 2016

Can Red Cell Distribution Width Be Used as a Marker of Crohn's Disease Activity?

GE Port J Gastroenterol 2016 Jan-Feb;23(1):6-12. Epub 2015 Nov 24.

Gastroenterology Department, Hospital Prof. Doutor Fernando Fonseca, Amadora, Portugal.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jpge.2015.10.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5579976PMC
November 2015

Isolated Visceral Angioedema Induced by Angiotensin-Converting Enzyme Inhibitor.

GE Port J Gastroenterol 2016 May-Jun;23(3):162-165. Epub 2015 Nov 24.

Gastroenterology Department, Hospital Prof. Doutor Fernando Fonseca, Amadora, Portugal.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jpge.2015.09.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5580168PMC
November 2015

Is there a proximal shift in the distribution of colorectal adenomas?

United European Gastroenterol J 2015 Aug;3(4):353-7

Department of Gastroenterology, Prof Doutor Fernando Fonseca Hospital, Amadora, Portugal.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1177/2050640615577534DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4528209PMC
August 2015

The resolution of central variant of posterior reversible encephalopathy syndrome.

Neurohospitalist 2015 Apr;5(2):91-2

Stroke Unit, Centro Hospitalar do Algarve, Faro, Portugal ; Department of Neurology, Centro Hospitalar do Algarve, Faro, Portugal.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1177/1941874414557082DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4357599PMC
April 2015

Assessing quality of life in middle-aged and older adults with HIV: psychometric testing of the WHOQOL-HIV-Bref.

Qual Life Res 2014 Nov 4;23(9):2473-9. Epub 2014 May 4.

Faculdade de Psicologia e Ciências da Educação, Universidade de Coimbra, Rua do Colégio Novo, Apartado 6153, 3001-802, Coimbra, Portugal,

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s11136-014-0707-7DOI Listing
November 2014

Lysine acetylsalicylate increases the safety of a paraquat formulation to freshwater primary producers: a case study with the microalga Chlorella vulgaris.

Aquat Toxicol 2014 Jan 7;146:137-43. Epub 2013 Nov 7.

REQUIMTE, Laboratory of Toxicology, Department of Biological Sciences, Faculty of Pharmacy, University of Porto, Rua Jorge Viterbo Ferreira, 228, 4050-313 Porto, Portugal. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.aquatox.2013.10.034DOI Listing
January 2014

Functional analysis of a large set of BRCA2 exon 7 variants highlights the predictive value of hexamer scores in detecting alterations of exonic splicing regulatory elements.

Hum Mutat 2013 Nov 18;34(11):1547-57. Epub 2013 Sep 18.

Inserm U1079, University of Rouen, Institute for Research and Innovation in Biomedicine, Rouen, France; Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/humu.22428DOI Listing
November 2013

Chronic toxicity of the veterinary antibiotic florfenicol to Daphnia magna assessed at two temperatures.

Environ Toxicol Pharmacol 2013 Nov 12;36(3):1022-32. Epub 2013 Sep 12.

ICBAS - Institute of Biomedical Sciences of Abel Salazar, Department of Populations Studies, Laboratory of Ecotoxicology, University of Porto, Rua Jorge Viterbo Ferreira, 228, 4050-313 Porto, Portugal; CIIMAR/CIMAR - Interdisciplinary Centre of Marine and Environmental Research, Laboratory of Ecotoxicology and Ecology, University of Porto, Rua dos Bragas, 289, 4050-123 Porto, Portugal. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.etap.2013.09.001DOI Listing
November 2013

Genital ulcers: do not forget Behçet disease.

BMJ Case Rep 2012 Feb 21;2012. Epub 2012 Feb 21.

Department of Gynaecology Obstetrics, Faro's Hospital, Faro, Portugal.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1136/bcr.11.2011.5069DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3291005PMC
February 2012

Use of splicing reporter minigene assay to evaluate the effect on splicing of unclassified genetic variants.

Methods Mol Biol 2010 ;653:249-57

Faculty of Medicine Department of Genetics and Institute for Biomedical Research, Rouen University Hospital, Inserm U614, IFRMP, University of Rouen, Northwest Canceropole, Rouen, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/978-1-60761-759-4_15DOI Listing
December 2010

Growing Teachers: using electives to teach senior residents how to teach.

Acad Psychiatry 2010 Jul-Aug;34(4):291-3

Department of Psychiatry, New York State Psychiatric Institute and New York Presbyterian Hospital at Columbia, New York, NY 10032, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1176/appi.ap.34.4.291DOI Listing
October 2010

Iron homeostasis and H63D mutations in alcoholics with and without liver disease.

World J Gastroenterol 2009 Jan;15(1):106-11

Unidade de Nutrição e Metabolismo, Instituto de Medicina Molecular, Faculdade de Medicina da Universidade de Lisboa, Portugal.

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2653287PMC
http://dx.doi.org/10.3748/wjg.15.106DOI Listing
January 2009

A large fraction of unclassified variants of the mismatch repair genes MLH1 and MSH2 is associated with splicing defects.

Hum Mutat 2008 Dec;29(12):1412-24

Inserm U614, Federate Institute for Multidisciplinary Research on Peptides, Faculty of Medicine, University of Rouen, Department of Genetics and Institute for Biomedical Research, Rouen University Hospital, Rouen, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/humu.20796DOI Listing
December 2008

Crystal structure and nonhomologous end-joining function of the ligase component of Mycobacterium DNA ligase D.

J Biol Chem 2006 May 13;281(19):13412-23. Epub 2006 Feb 13.

Department of Molecular and Cellular Biology, University of California, Berkeley, California 94720, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1074/jbc.M513550200DOI Listing
May 2006

An end-healing enzyme from Clostridium thermocellum with 5' kinase, 2',3' phosphatase, and adenylyltransferase activities.

RNA 2005 Aug 29;11(8):1271-80. Epub 2005 Jun 29.

Molecular Biology Program, Sloan-Kettering Institute, New York, NY 10021, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1261/rna.2690505DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1370810PMC
August 2005

Crystal structure of baculovirus RNA triphosphatase complexed with phosphate.

J Biol Chem 2005 May 15;280(18):17848-56. Epub 2005 Feb 15.

Department of Biochemistry, Molecular Biology, and Cell Biology, Northwestern University, Evanston, Illinois 60208, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1074/jbc.M500885200DOI Listing
May 2005

Mechanism of nonhomologous end-joining in mycobacteria: a low-fidelity repair system driven by Ku, ligase D and ligase C.

Nat Struct Mol Biol 2005 Apr 20;12(4):304-12. Epub 2005 Mar 20.

Immunology and Molecular Biology Programs, Sloan-Kettering Institute, and Division of Infectious Diseases, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nsmb915DOI Listing
April 2005

An RNA ligase from Deinococcus radiodurans.

J Biol Chem 2004 Dec 28;279(49):50654-61. Epub 2004 Aug 28.

The Molecular Biology Program, Sloan-Kettering Institute, New York, New York 10021, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1074/jbc.M407657200DOI Listing
December 2004

Biochemical and genetic analysis of the four DNA ligases of mycobacteria.

J Biol Chem 2004 May 25;279(20):20594-606. Epub 2004 Feb 25.

Molecular Biology and Immunology Programs, Sloan-Kettering Institute, and Infectious Disease Division, Memorial Sloan-Kettering Cancer Center, New York, NY 10021, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1074/jbc.M401841200DOI Listing
May 2004

Characterization of a baculovirus enzyme with RNA ligase, polynucleotide 5'-kinase, and polynucleotide 3'-phosphatase activities.

J Biol Chem 2004 Apr 26;279(18):18220-31. Epub 2004 Jan 26.

Molecular Biology Program, Sloan-Kettering Institute, New York, New York 10021, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1074/jbc.M313386200DOI Listing
April 2004

Structure-function analysis of Trypanosoma brucei RNA triphosphatase and evidence for a two-metal mechanism.

J Biol Chem 2003 Dec 1;278(51):50843-52. Epub 2003 Oct 1.

Molecular Biology Program, Sloan-Kettering Institute, New York, New York 10021, USA.

View Article

Download full-text PDF

Source
http://www.jbc.org/lookup/doi/10.1074/jbc.M309188200
Publisher Site
http://dx.doi.org/10.1074/jbc.M309188200DOI Listing
December 2003

Mapping the triphosphatase active site of baculovirus mRNA capping enzyme LEF4 and evidence for a two-metal mechanism.

Nucleic Acids Res 2003 Mar;31(5):1455-63

Molecular Biology Program, Sloan-Kettering Institute, New York, NY 10021, USA.

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC149837PMC
http://dx.doi.org/10.1093/nar/gkg244DOI Listing
March 2003

The domain order of mammalian capping enzyme can be inverted and baculovirus phosphatase can function in cap formation in vivo.

Virology 2002 Dec;304(2):167-75

Molecular Biology Program, Sloan-Ketterine Institute, New York, New York 10021, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1006/viro.2002.1606DOI Listing
December 2002

Mutational analysis of baculovirus phosphatase identifies structural residues important for triphosphatase activity in vitro and in vivo.

Biochemistry 2002 Nov;41(45):13403-9

Molecular Biology Program, Sloan-Kettering Institute, 1275 York Avenue, New York, New York 10021, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/bi0265426DOI Listing
November 2002