Publications by authors named "Alexandra Latini"

100Publications

Kynurenine, Tetrahydrobiopterin, and Cytokine Inflammatory Biomarkers in Individuals Affected by Diabetic Neuropathic Pain.

Front Neurosci 2020 21;14:890. Epub 2020 Aug 21.

Discipline of Anatomy and Histology, School of Medical Sciences, Faculty of Medicine and Health, The University of Sydney, Sydney, NSW, Australia.

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August 2020

The effect of voluntary wheel running on the antioxidant status is dependent on sociability conditions.

Pharmacol Biochem Behav 2020 11 20;198:173018. Epub 2020 Aug 20.

Department of Biochemistry, Federal University of Santa Catarina, 88040-900 Florianópolis, SC, Brazil.

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November 2020

Exposure to the herbicide 2,4-dichlorophenoxyacetic acid impairs mitochondrial function, oxidative status, and behavior in adult zebrafish.

Environ Sci Pollut Res Int 2020 Dec 16;27(36):45874-45882. Epub 2020 Aug 16.

Laboratório de Genética e Ecotoxicologia Molecular, Programa de Pós-Graduação em Ciências Ambientais, Universidade Comunitária da Região de Chapecó, Servidão Anjo da Guarda, 295-D, Efapi, Chapecó, SC, 89809-900, Brazil.

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December 2020

Novel immune biomarkers in complex regional pain syndrome.

J Neuroimmunol 2020 10 21;347:577330. Epub 2020 Jul 21.

Discipline of Anatomy & Histology, School of Medical Sciences, Faculty of Medicine and Health, The University of Sydney, NSW, 2006, Australia. Electronic address:

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October 2020

Physical Exercise Potentials Against Viral Diseases Like COVID-19 in the Elderly.

Front Med (Lausanne) 2020 3;7:379. Epub 2020 Jul 3.

Department of Pedagogy, Faculty of Human Sciences, Medical School Hamburg, Hamburg, Germany.

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July 2020

Kynurenine and Tetrahydrobiopterin Pathways Crosstalk in Pain Hypersensitivity.

Front Neurosci 2020 24;14:620. Epub 2020 Jun 24.

Laboratório de Bioenergética e Estresse Oxidativo, Departamento de Bioquímica, Centro de Ciências Biológicas, Universidade Federal de Santa Catarina, Florianópolis, Brazil.

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June 2020

Exercise-induced immune system response: Anti-inflammatory status on peripheral and central organs.

Biochim Biophys Acta Mol Basis Dis 2020 10 29;1866(10):165823. Epub 2020 Apr 29.

Laboratório de Bioenergética e Estresse Oxidativo, Departamento de Bioquímica, Centro de Ciências Biológicas, Universidade Federal de Santa Catarina, Florianópolis, SC, Brazil.

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October 2020

Editorial: Obesity and Diabetes: Implications for Brain-Immunometabolism.

Front Neurosci 2020 12;14:56. Epub 2020 Feb 12.

Laboratório de Bioenergética e Estresse Oxidativo - LABOX, Departamento de Bioquímica, Centro de Ciências Biológicas, Universidade Federal de Santa Catarina, Florianópolis, Brazil.

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February 2020

Glyphosate-based herbicide impairs energy metabolism and increases autophagy in C6 astroglioma cell line.

J Toxicol Environ Health A 2020 02 21;83(4):153-167. Epub 2020 Feb 21.

Laboratório De Biologia Celular, Coordenadoria Especial De Ciências Biológicas E Agronômicas, Universidade Federal De Santa Catarina - Campus De Curitibanos, Curitibanos, Brazil.

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February 2020

Temporal development of neurochemical and cognitive impairments following reserpine administration in rats.

Behav Brain Res 2020 04 30;383:112517. Epub 2020 Jan 30.

Graduate Program of Pharmacology, Center of Biological Sciences, Federal University of Santa Catarina, Florianópolis, SC, 88040-900, Brazil; Graduate Program of Neuroscience, Center of Biological Sciences, Federal University of Santa Catarina, Florianópolis, SC, 88040-900, Brazil.

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April 2020

Predictors of Pain Recurrence After Lumbar Facet Joint Injections.

Front Neurosci 2019 20;13:958. Epub 2019 Sep 20.

Center for Applied Neuroscience (CeNAp), University Hospital (HU), Federal University of Santa Catarina (UFSC), Florianópolis, Brazil.

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September 2019

Effects of photobiomodulation on mitochondria of brain, muscle, and C6 astroglioma cells.

Med Eng Phys 2019 09 11;71:108-113. Epub 2019 Jul 11.

Laboratório de Bioenergética e Estresse Oxidativo, Departamento de Bioquímica, Centro de Ciências Biológicas, Universidade Federal de Santa Catarina, 80040-900 Florianópolis, Santa Catarina state, Brazil.

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September 2019

Deep Brain Stimulation for Obesity: A Review and Future Directions.

Front Neurosci 2019 18;13:323. Epub 2019 Apr 18.

Center for Applied Neuroscience, University Hospital, Federal University of Santa Catarina, Florianópolis, Brazil.

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April 2019

Epigenetic modifications induced by exercise: Drug-free intervention to improve cognitive deficits associated with obesity.

Physiol Behav 2019 05 12;204:309-323. Epub 2019 Mar 12.

Laboratório de Bioenergética e Estresse Oxidativo (LABOX), Departamento de Bioquímica, Centro de Ciências Biológicas, Universidade Federal de Santa Catarina (UFSC), Florianópolis, Brazil. Electronic address:

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May 2019

Moderate running exercise prevents excessive immune system activation.

Physiol Behav 2019 05 19;204:248-255. Epub 2019 Feb 19.

Departamento de Bioquímica, Centro de Ciências Biológicas, Universidade Federal de Santa Catarina, Florianópolis, Brazil. Electronic address:

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May 2019

Oxidative Stress: Neuropathy, Excitability, and Neurodegeneration.

Oxid Med Cell Longev 2019 6;2019:2715326. Epub 2019 Jan 6.

Département de Pharmacologie et Physiologie, Faculté de Médecine, Université de Montréal, Montréal, QC, Canada H3C 3J7.

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March 2019

Impact of homocysteine on vasculogenic factors and bone formation in chicken embryos.

Cell Biol Toxicol 2019 02 30;35(1):49-58. Epub 2018 Jun 30.

Departamento de Biologia Celular, Embriologia e Genética, Centro de Ciências Biológicas, UFSC, Campus Universitário, Trindade, Florianópolis, SC, 88040-900, Brazil.

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February 2019

Chronic Metabolic Derangement-Induced Cognitive Deficits and Neurotoxicity Are Associated with REST Inactivation.

Mol Neurobiol 2019 Mar 14;56(3):1539-1557. Epub 2018 Jun 14.

Laboratório de Bioenergética e Estresse Oxidativo (LABOX), Departamento de Bioquímica, Centro de Ciências Biológicas, Universidade Federal de Santa Catarina (UFSC), Campus Universitário - Córrego Grande, Bloco C 201/214, Florianópolis, SC, 88040-900, Brazil.

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March 2019

Tetrahydrobiopterin improves hippocampal nitric oxide-linked long-term memory.

Mol Genet Metab 2018 09 11;125(1-2):104-111. Epub 2018 Jun 11.

Laboratório de Bioenergética e Estresse Oxidativo - LABOX, Departamento de Bioquímica, Centro de Ciências Biológicas, Universidade Federal de Santa Catarina, Florianópolis, SC, Brazil; Centre de Psychiatrie et Neurosciences, INSERM UMR 894, Paris, France.

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September 2018

Low-concentration exposure to glyphosate-based herbicide modulates the complexes of the mitochondrial respiratory chain and induces mitochondrial hyperpolarization in the Danio rerio brain.

Chemosphere 2018 Oct 11;209:353-362. Epub 2018 Jun 11.

Departamento de Biologia Celular, Embriologia e Genética, Centro de Ciências Biológicas, Universidade Federal de Santa Catarina, 88040-900, Brazil. Electronic address:

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October 2018

De novo tetrahydrobiopterin biosynthesis is impaired in the inflammed striatum of parkin mice.

Cell Biol Int 2018 Jun 26;42(6):725-733. Epub 2018 Apr 26.

Laboratório de Bioenergética e Estresse Oxidativo-LABOX, Departamento de Bioquímica, Centro de Ciências Biológicas, Universidade Federal de Santa Catarina, Florianópolis, Brazil.

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June 2018

Oxidative stress and mitochondrial adaptive shift during pituitary tumoral growth.

Free Radic Biol Med 2018 05 13;120:41-55. Epub 2018 Mar 13.

Universidad Nacional de Córdoba, Facultad de Ciencias Médicas, Centro de Microscopía Electrónica. Instituto de Investigaciones en Ciencias de la Salud (INICSA-CONICET), Av. Enrique Barros y Enfermera Gordillo, Ciudad Universitaria, 5000 Córdoba, Argentina. Electronic address:

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May 2018

Neopterin preconditioning prevents inflammasome activation in mammalian astrocytes.

Free Radic Biol Med 2018 02 2;115:371-382. Epub 2017 Dec 2.

Laboratório de Bioenergética e Estresse Oxidativo - LABOX, Departamento de Bioquímica, Universidade Federal de Santa Catarina, Campus Universitário, Córrego Grande, Florianópolis, SC 88040-900, Brazil. Electronic address:

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February 2018

Neuropsychological functioning and brain energetics of drug resistant mesial temporal lobe epilepsy patients.

Epilepsy Res 2017 12 12;138:26-31. Epub 2017 Oct 12.

Centro de Neurociências Aplicadas, Hospital Universitário (HU), Universidade Federal de Santa Catarina (UFSC), Florianópolis, SC, Brazil; Centro de Epilepsia do Estado de Santa Catarina, CEPESC, HU, UFSC, Florianópolis, SC, Brazil; Serviço de Neurologia, Departamento de Clínica Médica, HU, UFSC, Florianópolis, SC, Brazil. Electronic address:

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December 2017

Uric acid activates NRLP3 inflammasome in an in-vivo model of epithelial to mesenchymal transition in the kidney.

J Mol Histol 2017 Jun 3;48(3):209-218. Epub 2017 Apr 3.

Facultad de Ciencias Médicas, Centro de Microscopía Electrónica, Instituto de Investigaciones en Ciencias de la Salud (INICSA-CONICET), Universidad Nacional de Córdoba, Av. Haya de la Torre 1er Piso, Ciudad Universitaria, 5000, Córdoba, Argentina.

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June 2017

1,25(OH)2 vitamin D3 signalling on immature rat Sertoli cells: gamma-glutamyl transpeptidase and glucose metabolism.

J Cell Commun Signal 2017 Sep 3;11(3):233-243. Epub 2017 Feb 3.

Departamento de Bioquímica, Centro de Ciências Biológicas, Universidade Federal de Santa Catarina, Campus Universitário, Bairro Trindade, Cx Postal 5069, Florianópolis, Santa Catarina, CEP: 88040-970, Brazil.

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September 2017

Running for REST: Physical activity attenuates neuroinflammation in the hippocampus of aged mice.

Brain Behav Immun 2017 Mar 29;61:31-35. Epub 2016 Jul 29.

Laboratório de Bioenergética e Estresse Oxidativo (LABOX), Departamento de Bioquímica, Universidade Federal de Santa Catarina, UFSC, Centro de Ciências Biológicas, CCB, Florianópolis, SC 88049-900, Brazil; Grupo de Pesquisa Neurobiologia do Exercício Físico, Departamento de Fisioterapia, Universidade Federal de Santa Catarina, 88906-072 Araranguá, Brazil. Electronic address:

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March 2017

Low-level laser therapy attenuates the acute inflammatory response induced by muscle traumatic injury.

Free Radic Res 2016 17;50(5):503-13. Epub 2016 Mar 17.

a Laboratório de Bioenergética e Estresse Oxidativo - LABOX, Departamento de Bioquímica , Universidade Federal de Santa Catarina , Florianópolis , Brazil ;

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December 2016

Neopterin acts as an endogenous cognitive enhancer.

Brain Behav Immun 2016 Aug 23;56:156-64. Epub 2016 Feb 23.

Laboratório de Bioenergética e Estresse Oxidativo - LABOX, Departamento de Bioquímica, Universidade Federal de Santa Catarina, Florianópolis, SC 88040-900, Brazil. Electronic address:

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August 2016

Neopterin as a potential cytoprotective brain molecule.

J Psychiatr Res 2015 Dec 9;71:134-9. Epub 2015 Oct 9.

Laboratório de Bioenergética e Estresse Oxidativo - LABOX, Departamento de Bioquímica, Universidade Federal de Santa Catarina, Florianópolis, SC, Brazil. Electronic address:

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December 2015

Moderate-Intensity Physical Exercise Protects Against Experimental 6-Hydroxydopamine-Induced Hemiparkinsonism Through Nrf2-Antioxidant Response Element Pathway.

Neurochem Res 2016 Feb 1;41(1-2):64-72. Epub 2015 Sep 1.

Laboratório Experimental de Doenças Neurodegenerativas (LEXDON), Departamento de Farmacologia, Centro de Ciências Biológicas, Universidade Federal de Santa Catarina, 88049-900, Florianópolis, Brazil.

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February 2016

Evidence of cellular senescence during the development of estrogen-induced pituitary tumors.

Endocr Relat Cancer 2015 06 19;22(3):299-317. Epub 2015 Mar 19.

Facultad de Ciencias MédicasInstituto de Investigaciones en Ciencias de la Salud (INICSA-CONICET), Centro de Microscopía Electrónica, Universidad Nacional de Córdoba, Av. Enrique Barros y Enfermera Gordillo, Ciudad Universitaria, 5000 Córdoba, ArgentinaLaboratorio de Bioenergética y Estrés OxidativoDepartamento de Bioquímica, Centro de Ciencias Biológicas, Universidad Federal de Santa Catarina, Florianópolis, Brazil

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June 2015

Kuehne LK, Reiber H, Bechter K, Hagberg L, Fuchs D., Cerebrospinal fluid neopterin is brain-derived and not associated with blood-CSF barrier dysfunction in non-inflammatory affective and schizophrenic spectrum disorders. Journal of Psychiatric Research, Volume 47, Issue 10, October 2013, pages 1417-1422.

J Psychiatr Res 2015 Apr 25;63:141-2. Epub 2015 Feb 25.

Biochemistry Department, Center for Biological Sciences, Universidade Federal de Santa Catarina, Campus Universitário, Trindade, Bloco C, 2° Andar, Rooms 201/205/214, 88040-900, Florianópolis, SC, Brazil. Electronic address:

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April 2015

Neuroprotective effects of a brain permeant 6-aminoquinoxaline derivative in cell culture conditions that model the loss of dopaminergic neurons in Parkinson disease.

Eur J Med Chem 2015 Jan 23;89:467-79. Epub 2014 Oct 23.

Centre Nationale de la Recherche Scientifique (CNRS), Unité mixte de recherche (UMR) 8076 BioCIS, LabEx LERMIT, Laboratoire de Pharmacognosie, Université Paris-Sud, Faculté de Pharmacie, Châtenay-Malabry, France. Electronic address:

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January 2015

Diphenyl diselenide administration enhances cortical mitochondrial number and activity by increasing hemeoxygenase type 1 content in a methylmercury-induced neurotoxicity mouse model.

Mol Cell Biochem 2014 May 13;390(1-2):1-8. Epub 2014 Mar 13.

Laboratório de Bioenergética e Estresse Oxidativo, Departamento de Bioquímica, Centro de Ciências Biológicas, Universidade Federal de Santa Catarina, Campus Universitário - Córrego Grande, Bloco C-201/214, Florianópolis, SC, 88040-900, Brazil.

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May 2014

Protective effects of diphenyl diselenide in a mouse model of brain toxicity.

Chem Biol Interact 2013 Oct 14;206(1):18-26. Epub 2013 Aug 14.

Departamento de Bioquímica, Centro de Ciências Biológicas, Universidade Federal de Santa Catarina, Florianópolis, SC, Brazil.

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October 2013

Six weeks of voluntary exercise don't protect C57BL/6 mice against neurotoxicity of MPTP and MPP(+).

Neurotox Res 2014 Feb 20;25(2):147-52. Epub 2013 Jul 20.

Departamento de Bioquímica, Centro de Ciências Biológicas (CCB), Universidade Federal de Santa Catarina (UFSC), Florianópolis, SC, 88040-900, Brazil,

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February 2014

Effect of ultraviolet-B radiation in laboratory on morphological and ultrastructural characteristics and physiological parameters of selected cultivar of Oryza sativa L.

Protoplasma 2013 Dec 25;250(6):1303-13. Epub 2013 May 25.

Post-Graduate Program in Cell Biology and Development, Department of Cell Biology, Embryology and Genetics, Federal University of Santa Catarina, 88049-900, CP 476, Florianópolis, SC, Brazil.

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December 2013

Resveratrol protects C6 astrocyte cell line against hydrogen peroxide-induced oxidative stress through heme oxygenase 1.

PLoS One 2013 15;8(5):e64372. Epub 2013 May 15.

Departamento de Bioquímica, Programa de Pós-Graduação em Ciências Biológicas: Bioquímica, Instituto de Ciências Básicas da Saúde, Universidade Federal do Rio Grande do Sul, Porto Alegre, Rio Grande do Sul, Brazil.

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January 2014

Disubstituted diaryl diselenides as potential atheroprotective compounds: Involvement of TrxR and GPx-like systems.

Eur J Pharm Sci 2013 Mar 21;48(4-5):717-25. Epub 2013 Jan 21.

Departamento de Bioquímica, Centro de Ciências Biológicas, Universidade Federal de Santa Catarina, Florianópolis, SC 88040900, Brazil.

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March 2013

Impact of different resistance training protocols on muscular oxidative stress parameters.

Appl Physiol Nutr Metab 2012 Dec 12;37(6):1239-46. Epub 2012 Nov 12.

Universidade do Extremo Sul Catarinense, Bairro Universitário, Criciúma, Brazil.

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December 2012

Lithium and valproate prevent olfactory discrimination and short-term memory impairments in the intranasal 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) rat model of Parkinson's disease.

Behav Brain Res 2012 Apr 17;229(1):208-15. Epub 2012 Jan 17.

Departamento de Farmacologia, Universidade Federal de Santa Catarina, Campus Trindade, Florianópolis, SC, 88049-900, Brazil.

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April 2012

Alterations in architecture and metabolism induced by ultraviolet radiation-B in the carragenophyte Chondracanthus teedei (Rhodophyta, Gigartinales).

Protoplasma 2012 Apr 8;249(2):353-67. Epub 2011 Jun 8.

Post-Graduate Program in Cell Biology and Development, Department of Cell Biology, Embryology and Genetics, Federal University of Santa Catarina, 88049-900, CP 476, Florianópolis, SC, Brazil.

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April 2012

Neurobiological alterations induced by exercise and their impact on depressive disorders [corrected].

Clin Pract Epidemiol Ment Health 2010 Nov 30;6:115-25. Epub 2010 Nov 30.

Department of Neurology, Psychosomatic Medicine, and Psychiatry, Institute of Health Promotion and Clinical Movement Science, German Sports University Cologne, Germany.

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November 2010

Hydroxyl containing seleno-imine compound exhibits improved anti-oxidant potential and does not inhibit thiol-containing enzymes.

Chem Biol Interact 2011 Mar 21;190(1):35-44. Epub 2011 Jan 21.

Departamento de Química, Centro de Ciências Naturais e Exatas, Universidade Federal de Santa Maria, Santa Maria CEP 97105-900, RS, Brazil. waseem

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March 2011

Folic acid plus α-tocopherol mitigates amyloid-β-induced neurotoxicity through modulation of mitochondrial complexes activity.

J Alzheimers Dis 2011 ;24(1):61-75

Departamento de Farmacologia, Centro de ciências Biológicas, Universidade Federal de Santa Catarina, Florianópolis, Santa Catarina, Brazil.

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March 2012

Effects of low-power laser irradiation (LPLI) at different wavelengths and doses on oxidative stress and fibrogenesis parameters in an animal model of wound healing.

Lasers Med Sci 2011 Jan 24;26(1):125-31. Epub 2010 Sep 24.

Exercise Biochemistry and Physiology Laboratory, Postgraduate Program in Health Sciences, Health Sciences Unit, University of Southern Santa Catarina, Criciúma, SC, Brazil.

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January 2011

Effects of inorganic selenium administration in methylmercury-induced neurotoxicity in mouse cerebral cortex.

Int J Dev Neurosci 2010 Nov 8;28(7):631-7. Epub 2010 Jul 8.

Laboratório de Bioenergética e Estresse Oxidativo, Departamento de Bioquímica, Centro de Ciências Biológicas, Universidade Federal de Santa Catarina, Florianópolis, SC, Brazil.

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November 2010

The intra-hippocampal leucine administration impairs memory consolidation and LTP generation in rats.

Cell Mol Neurobiol 2010 Oct 26;30(7):1067-75. Epub 2010 Jun 26.

Laboratório de Bioenergética e Estresse Oxidativo, Departamento de Bioquímica, Centro de Ciências Biológicas, Universidade Federal de Santa Catarina, Campus Universitário-Trindade, Florianópolis, SC, Brazil.

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October 2010

Oxidative stress-mediated inhibition of brain creatine kinase activity by methylmercury.

Neurotoxicology 2010 Sep 4;31(5):454-60. Epub 2010 Jun 4.

Laboratório de Bioenergética e Estresse Oxidativo, Departamento de Bioquímica, Centro de Ciências Biológicas, Universidade Federal de Santa Catarina, Campus Universitário-Trindade, Florianópolis, SC, Brazil.

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September 2010

Effects of environmental and artificial UV-B radiation on freshwater prawn Macrobrachium olfersi embryos.

Aquat Toxicol 2010 Jun 25;98(1):25-33. Epub 2010 Jan 25.

Programa de Pós-Graduação em Ciências Morfológicas, Instituto de Ciências Biomédicas, Universidade Federal do Rio de Janeiro, 21949-902 Rio de Janeiro, RJ, Brazil.

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June 2010

The janus face of resveratrol in astroglial cells.

Neurotox Res 2009 Jul 26;16(1):30-41. Epub 2009 Mar 26.

Departamento de Bioquímica, Instituto de Ciências Básicas da Saúde, Universidade Federal do Rio Grande do Sul, Rua Ramiro Barcelos 2600 anexo, Porto Alegre, RS, 90035-003, Brazil.

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July 2009

Synergistic neurotoxicity induced by methylmercury and quercetin in mice.

Food Chem Toxicol 2009 Mar 25;47(3):645-9. Epub 2008 Dec 25.

Departamento de Bioquímica, Centro de Ciências Biológicas, Universidade Federal de Santa Catarina, Campus Trindade, 88040-900 Florianópolis, SC, Brazil.

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March 2009

Antioxidant and pro-oxidant properties of boldine on hippocampal slices exposed to oxygen-glucose deprivation in vitro.

Neurotoxicology 2008 Nov 11;29(6):1136-40. Epub 2008 Jun 11.

Curso de Pós-Graduação em Ciências Farmacêuticas, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil.

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November 2008

Tryptophan administration induces oxidative stress in brain cortex of rats.

Metab Brain Dis 2008 Jun 19;23(2):221-33. Epub 2008 Apr 19.

Departamento de Bioquímica, Instituto de Ciências Básicas da Saúde, Universidade Federal do Rio Grande do Sul, Porto Alegre, Rio Grande do Sul, Brazil.

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June 2008

Induction of oxidative stress by the metabolites accumulating in 3-methylglutaconic aciduria in cerebral cortex of young rats.

Life Sci 2008 Mar 11;82(11-12):652-62. Epub 2008 Jan 11.

Departamento de Bioquímica, Instituto de Ciências Básicas da Saúde, Universidade Federal de Rio Grande do Sul, Porto Alegre-RS, Brazil.

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March 2008

Oxidative stress induction by cis-4-decenoic acid: relevance for MCAD deficiency.

Free Radic Res 2007 Nov;41(11):1261-72

Departamento de Bioquímica, Instituto de Ciências Básicas da Saúde, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil.

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November 2007

Evidence for a synergistic action of glutaric and 3-hydroxyglutaric acids disturbing rat brain energy metabolism.

Int J Dev Neurosci 2007 Oct 19;25(6):391-8. Epub 2007 Jun 19.

Departamento de Bioquímica, Instituto de Ciências Básicas da Saúde, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil.

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October 2007

Induction of oxidative stress by chronic and acute glutaric acid administration to rats.

Cell Mol Neurobiol 2007 Jun 19;27(4):423-38. Epub 2007 Jan 19.

Departamento de Bioquímica, Instituto de Ciências Básicas da Saúde, Universidade Federal do Rio Grande do Sul, Rua Ramiro Barcelos, 2600 Anexo, Porto Alegre, RS, Brazil.

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June 2007

Energy metabolism is compromised in skeletal muscle of rats chronically-treated with glutaric acid.

Metab Brain Dis 2007 Mar 13;22(1):111-23. Epub 2007 Jan 13.

Departamento de Bioquímica, Instituto de Ciências Básicas da Saúde, Universidade Federal do Rio Grande do Sul, Rua Ramiro Barcelos, 2600, Anexo, Porto Alegre, RS, Brazil.

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March 2007

Kynurenines impair energy metabolism in rat cerebral cortex.

Cell Mol Neurobiol 2007 Feb 7;27(1):147-60. Epub 2006 Dec 7.

Departamento de Bioquímica, Instituto de Ciências Básicas da Saúde, Universidade Federal do Rio Grande do Sul, Rua Ramiro Barcelos, 2600- Anexo, CEP 90035-003, Porto Alegre, RS, Brazil.

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February 2007

In vitro effect of quinolinic acid on energy metabolism in brain of young rats.

Neurosci Res 2007 Feb 28;57(2):277-88. Epub 2006 Nov 28.

Departamento de Bioquímica, Instituto de Ciências Básicas da Saúde, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil.

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February 2007

In vitro evidence for an antioxidant role of 3-hydroxykynurenine and 3-hydroxyanthranilic acid in the brain.

Neurochem Int 2007 Jan 7;50(1):83-94. Epub 2006 Sep 7.

Departamento de Bioquímica, Instituto de Ciências Básicas da Saúde, Universidade Federal de Rio Grande do Sul, Porto Alegre, RS, Brazil.

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January 2007

Promotion of oxidative stress by L-tryptophan in cerebral cortex of rats.

Neurochem Int 2006 Jul 23;49(1):87-93. Epub 2006 Feb 23.

Departamento de Bioquímica, Instituto de Ciências Básicas da Saúde, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil.

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July 2006

Glutaric acid moderately compromises energy metabolism in rat brain.

Int J Dev Neurosci 2005 Dec 14;23(8):687-93. Epub 2005 Nov 14.

Departamento de Bioquímica, Instituto de Ciências Básicas da Saúde, Universidade Federal do Rio Grande do Sul, Rua Ramiro Barcelos, 2600 Anexo, Porto Alegre, RS, Brazil.

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December 2005

Quinolinic acid reduces the antioxidant defenses in cerebral cortex of young rats.

Int J Dev Neurosci 2005 Dec 5;23(8):695-701. Epub 2005 Oct 5.

Departamento de Bioquímica, Instituto de Ciências Básicas da Saúde, Universidade Federal de Rio Grande do Sul, Rua Ramiro Barcelos N 2600 - Anexo, CEP 90035-003, Porto Alegre, RS, Brazil.

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December 2005

Mitochondrial energy metabolism is markedly impaired by D-2-hydroxyglutaric acid in rat tissues.

Mol Genet Metab 2005 Sep-Oct;86(1-2):188-99. Epub 2005 Jun 15.

Departamento de Bioquímica, Instituto de Ciências Básicas da Saúde, Universidade Federal do Rio Grande do Sul, Porto Alegre-RS, Brazil.

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January 2006

Evaluation of the mechanisms involved in leucine-induced oxidative damage in cerebral cortex of young rats.

Free Radic Res 2005 Jan;39(1):71-9

Departamento de Bioquimica, Instituto de Ciências Báisicas da Saúde, Universidade Federal do Rio Grande do Sul, Rua Ramiro Barcelos, 2600 Anexo, CEP 90035-003, Porto, Alegre RS, Brazil.

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January 2005

Induction of oxidative stress by L-2-hydroxyglutaric acid in rat brain.

J Neurosci Res 2003 Oct;74(1):103-10

Departamento de Bioquímica, Instituto de Ciências Básicas da Saúde, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil.

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October 2003