Alexandra L Orton

Alexandra L Orton

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Alexandra L Orton

Alexandra L Orton

Publications by authors named "Alexandra L Orton"

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Drug Metabolite Identification using UHPLC UV Spectroscopy and Parallelized Scans on a Tribrid Orbitrap Mass Spectrometer.

Rapid Commun Mass Spectrom 2020 Jan 22:e8735. Epub 2020 Jan 22.

Radiolabelled Chemistry & Metabolism, Pharmaron, Pegasus Way, Crown Business Park, Rushden, NN10 6ER, UK.

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http://dx.doi.org/10.1002/rcm.8735DOI Listing
January 2020

Expanding the Armory: Predicting and Tuning Covalent Warhead Reactivity.

J Chem Inf Model 2017 12 21;57(12):3124-3137. Epub 2017 Nov 21.

Chemistry and DMPK, Oncology, IMED Biotech Unit, AstraZeneca , Cambridge CB4 0WG, UK.

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http://dx.doi.org/10.1021/acs.jcim.7b00553DOI Listing
December 2017

Methanol adducts leading to the identification of a reactive aldehyde metabolite of CPAQOP in human liver microsomes by ultra-high-performance liquid chromatography/mass spectrometry.

Rapid Commun Mass Spectrom 2017 Jan;31(1):145-151

Biomedical Research Centre, Sheffield Hallam University, Howard Street, Sheffield, S1 1WB, UK.

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http://dx.doi.org/10.1002/rcm.7772DOI Listing
January 2017