Alexandr A Kapralov

Alexandr A Kapralov

UNVERIFIED PROFILE

Are you Alexandr A Kapralov?   Register this Author

Register author
Alexandr A Kapralov

Alexandr A Kapralov

Publications by authors named "Alexandr A Kapralov"

Are you Alexandr A Kapralov?   Register this Author

25Publications

358Reads

-Profile Views

Targeting myeloid regulators by paclitaxel-loaded enzymatically degradable nanocups.

Nanoscale 2018 Sep;10(37):17990-18000

Department of Chemistry, University of Pittsburgh, Pittsburgh, Pennsylvania 15260, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1039/c8nr04437fDOI Listing
September 2018

PEBP1 Wardens Ferroptosis by Enabling Lipoxygenase Generation of Lipid Death Signals.

Cell 2017 Oct;171(3):628-641.e26

Department of Environmental and Occupational Health, Center for Free Radical and Antioxidant Health, University of Pittsburgh, Pittsburgh, PA, USA; Department of Chemistry, University of Pittsburgh, Pittsburgh, PA, USA; Department of Pharmacology and Chemical Biology, University of Pittsburgh, Pittsburgh, PA, USA; Department of Radiation Oncology, University of Pittsburgh, Pittsburgh, PA, USA. Electronic address:

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S00928674173113
Publisher Site
http://dx.doi.org/10.1016/j.cell.2017.09.044DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5683852PMC
October 2017

Enzymatic oxidative biodegradation of nanoparticles: Mechanisms, significance and applications.

Toxicol Appl Pharmacol 2016 May 6;299:58-69. Epub 2016 Jan 6.

Department of Environmental and Occupational Health, Center for Free Radical and Antioxidant Health, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA 15219, United States; Department of Chemistry, University of Pittsburgh, Pittsburgh, PA 15260, United States; Departments of Pharmacology and Chemical Biology and Radiation Oncology, University of Pittsburgh, Pittsburgh, PA 15260, United States. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.taap.2016.01.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4811710PMC
May 2016

Peroxidase activation of cytoglobin by anionic phospholipids: Mechanisms and consequences.

Biochim Biophys Acta 2016 May 27;1861(5):391-401. Epub 2016 Feb 27.

Department of Environmental and Occupational Health, University of Pittsburgh, Pittsburgh, PA 15219, USA; Center for Free Radical and Antioxidant Health and Center for Medical Countermeasures against Radiation, University of Pittsburgh, Pittsburgh, PA 15219, USA; Department of Chemistry, University of Pittsburgh, Pittsburgh, PA 15219, USA; Department of Pharmacology and Chemical Biology, University of Pittsburgh, Pittsburgh, PA 15219, USA; Department of Radiation Oncology, University of Pittsburgh, Pittsburgh, PA 15219, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bbalip.2016.02.022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4821708PMC
May 2016

Inhibition of Peroxidase Activity of Cytochrome c: De Novo Compound Discovery and Validation.

Mol Pharmacol 2015 Sep 15;88(3):421-7. Epub 2015 Jun 15.

Department of Computational and Systems Biology, School of Medicine (A.B., F.H., I.B.), and Department of Environmental and Occupational Health (A.A.K., H.B., V.E.K.), University of Pittsburgh, Pittsburgh, Pennsylvania

View Article

Download full-text PDF

Source
http://molpharm.aspetjournals.org/content/early/2015/06/15/m
Web Search
http://molpharm.aspetjournals.org/content/88/3/421.full.pdf
Web Search
http://molpharm.aspetjournals.org/cgi/doi/10.1124/mol.115.09
Publisher Site
http://dx.doi.org/10.1124/mol.115.097816DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4551054PMC
September 2015

Nano-gold corking and enzymatic uncorking of carbon nanotube cups.

J Am Chem Soc 2015 Jan 7;137(2):675-84. Epub 2015 Jan 7.

Department of Chemistry, University of Pittsburgh , Pittsburgh, Pennsylvania 15260, United States.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/ja511843wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4308760PMC
January 2015

Designing inhibitors of cytochrome c/cardiolipin peroxidase complexes: mitochondria-targeted imidazole-substituted fatty acids.

Free Radic Biol Med 2014 Jun 12;71:221-30. Epub 2014 Mar 12.

Center for Free Radical and Antioxidant Health and Center for Medical Countermeasures against Radiation, University of Pittsburgh, Pittsburgh, PA 15219, USA; Department of Environmental and Occupational Health, University of Pittsburgh, Pittsburgh, PA 15219, USA; Department of Chemistry, University of Pittsburgh, Pittsburgh, PA 15219, USA; Department of Pharmacology and Chemical Biology, and University of Pittsburgh, Pittsburgh, PA 15219, USA; Department of Radiation Oncology, University of Pittsburgh, Pittsburgh, PA 15219, USA. Electronic address:

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S08915849140010
Publisher Site
http://dx.doi.org/10.1016/j.freeradbiomed.2014.02.029DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4216591PMC
June 2014

Lung macrophages "digest" carbon nanotubes using a superoxide/peroxynitrite oxidative pathway.

ACS Nano 2014 Jun 4;8(6):5610-21. Epub 2014 Jun 4.

Center for Free Radical and Antioxidant Health, △Acute Lung Injury Center of Excellence, ‡Departments of Environmental and Occupational Health, §Cell Biology and Physiology, ⊥Chemistry, and ⊗Medicine, University of Pittsburgh , Pittsburgh, Pennsylvania, United States.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/nn406484bDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4072413PMC
June 2014

LC/MS characterization of rotenone induced cardiolipin oxidation in human lymphocytes: implications for mitochondrial dysfunction associated with Parkinson's disease.

Mol Nutr Food Res 2013 Aug 3;57(8):1410-22. Epub 2013 May 3.

Center for Free Radical and Antioxidant Health, Department of Environmental and Occupational Health, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA 15219, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/mnfr.201200801DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3810210PMC
August 2013

Succinobucol induces apoptosis in vascular smooth muscle cells.

Free Radic Biol Med 2012 Mar 21;52(5):871-9. Epub 2011 Dec 21.

Centre for Vascular Research, Bosch Institute, University of Sydney, Sydney, NSW 2006, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.freeradbiomed.2011.11.029DOI Listing
March 2012

Nitric oxide inhibits peroxidase activity of cytochrome c.cardiolipin complex and blocks cardiolipin oxidation.

J Biol Chem 2006 May 16;281(21):14554-62. Epub 2006 Mar 16.

Center for Free Radical and Antioxidant Health, Department of Environmental and Occupational Health, University of Pittsburgh, 100 Technology Drive, Pittsburgh, PA 15260, USA.

View Article

Download full-text PDF

Source
http://www.jbc.org/content/281/21/14554.full.pdf
Web Search
http://www.jbc.org/cgi/doi/10.1074/jbc.M509507200
Publisher Site
http://dx.doi.org/10.1074/jbc.M509507200DOI Listing
May 2006

Peroxidase activity and structural transitions of cytochrome c bound to cardiolipin-containing membranes.

Biochemistry 2006 Apr;45(15):4998-5009

Center for Free Radical and Antioxidant Health and Department of Environmental and Occupational Health, University of Pittsburgh, 100 Technology Drive, Suite 350, Pittsburgh, Pennsylvania 15219-3130, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/bi0525573DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2527545PMC
April 2006

Cytochrome c acts as a cardiolipin oxygenase required for release of proapoptotic factors.

Nat Chem Biol 2005 Sep 14;1(4):223-32. Epub 2005 Aug 14.

Center for Free Radical and Antioxidant Health and Department of Environmental and Occupational Health, University of Pittsburgh, Pittsburgh, Pennsylvania 15260, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nchembio727DOI Listing
September 2005