Alexander Y F Chung

Alexander Y F Chung

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Alexander Y F Chung

Alexander Y F Chung

Publications by authors named "Alexander Y F Chung"

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Critical Appraisal of the Impact of the Systematic Adoption of Advanced Minimally Invasive Hepatobiliary and Pancreatic Surgery on the Surgical Management of Mirizzi Syndrome.

World J Surg 2019 Sep 16. Epub 2019 Sep 16.

Department of Hepatopancreatobiliary and Transplantation Surgery, Singapore General Hospital, 20 College Road, Academia, Singapore, 169856, Singapore.

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http://dx.doi.org/10.1007/s00268-019-05164-yDOI Listing
September 2019

Comprehensive analysis of transcriptome profiles in hepatocellular carcinoma.

J Transl Med 2019 Aug 20;17(1):273. Epub 2019 Aug 20.

Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, 119077, Singapore.

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http://dx.doi.org/10.1186/s12967-019-2025-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6701074PMC
August 2019

Minimally-invasive versus open enucleation for pancreatic tumours: A propensity-score adjusted analysis.

Ann Hepatobiliary Pancreat Surg 2019 Aug 30;23(3):258-264. Epub 2019 Aug 30.

Department of Hepatopancreatobiliary and Transplant Surgery, Singapore General Hospital, Singapore.

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http://dx.doi.org/10.14701/ahbps.2019.23.3.258DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6728251PMC
August 2019

Initial single institution experience with robotic biliary surgery and bilio-enteric anastomosis in southeast Asia.

ANZ J Surg 2019 Apr 18;89(4):E142-E146. Epub 2019 Mar 18.

Department of Hepatopancreatobiliary and Transplant Surgery, Singapore General Hospital, Singapore.

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http://dx.doi.org/10.1111/ans.15135DOI Listing
April 2019

Initial experience with robotic pancreatic surgery in Singapore: single institution experience with 30 consecutive cases.

ANZ J Surg 2019 Mar 24;89(3):206-210. Epub 2018 May 24.

Department of Hepatopancreatobiliary and Transplant Surgery, Singapore General Hospital, Singapore.

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http://dx.doi.org/10.1111/ans.14673DOI Listing
March 2019

Perioperative Outcomes of Laparoscopic Repeat Liver Resection for Recurrent HCC: Comparison with Open Repeat Liver Resection for Recurrent HCC and Laparoscopic Resection for Primary HCC.

World J Surg 2019 Mar;43(3):878-885

Department of Hepatopancreatobiliary and Transplant Surgery, Singapore General Hospital, 20 College Road, Academia, Singapore, 169856, Singapore.

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http://dx.doi.org/10.1007/s00268-018-4828-yDOI Listing
March 2019

Laparoscopic Liver Resection Difficulty Score-a Validation Study.

J Gastrointest Surg 2019 Mar 12;23(3):545-555. Epub 2018 Nov 12.

Department of Hepatopancreatobiliary and Transplant Surgery, Singapore General Hospital, 20 College Road, Singapore, 169856, Singapore.

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http://link.springer.com/10.1007/s11605-018-4036-y
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http://dx.doi.org/10.1007/s11605-018-4036-yDOI Listing
March 2019

External validation of the Japanese difficulty scoring system for minimally-invasive distal pancreatectomies.

Am J Surg 2019 Mar 15. Epub 2019 Mar 15.

Department of Hepatopancreatobiliary and Transplant Surgery, Singapore General Hospital, 20 College Road, Level 5 Academia, 169856, Singapore; Duke NUS Medical School, Singapore.

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http://dx.doi.org/10.1016/j.amjsurg.2019.03.012DOI Listing
March 2019

A Retrospective Review of the Diagnostic and Management Challenges of Mirizzi Syndrome at the Singapore General Hospital.

Dig Surg 2018 30;35(6):491-497. Epub 2017 Nov 30.

Department of Hepatopancreatobiliary and Transplant Surgery, Singapore General Hospital, Singapore, Singapore.

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http://dx.doi.org/10.1159/000484256DOI Listing
January 2019

Perioperative Outcomes of Laparoscopic Minor Hepatectomy for Hepatocellular Carcinoma in the Elderly.

World J Surg 2018 12;42(12):4063-4069

Department of Hepatopancreatobiliary and Transplant Surgery, Singapore General Hospital, 20 College Road, Academia, Singapore, 169856, Singapore.

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http://dx.doi.org/10.1007/s00268-018-4741-4DOI Listing
December 2018

Changing trends and outcomes associated with the adoption of minimally invasive hepatectomy: a contemporary single-institution experience with 400 consecutive resections.

Surg Endosc 2018 11 2;32(11):4658-4665. Epub 2018 Jul 2.

Department of Hepatopancreatobiliary and Transplant Surgery, Singapore General Hospital, Level 5, 20 College Road, Academia, Singapore, 169856, Singapore.

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http://dx.doi.org/10.1007/s00464-018-6310-1DOI Listing
November 2018

Early experience with totally laparoscopic major hepatectomies: single institution experience with 31 consecutive cases.

ANZ J Surg 2018 Apr 3;88(4):E329-E333. Epub 2017 May 3.

Department of Hepatopancreatobiliary and Transplant Surgery, Singapore General Hospital, Singapore.

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http://dx.doi.org/10.1111/ans.13959DOI Listing
April 2018

Preoperative Prognostic Factors After Liver Resection for Non-Colorectal, Non-Neuroendocrine Liver Metastases and Validation of the Adam Score in an Asian Population.

World J Surg 2018 04;42(4):1073-1084

Department of Hepatopancreatobiliary and Transplant Surgery, Singapore General Hospital, 20 College Road, Singapore, 169856, Singapore.

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http://dx.doi.org/10.1007/s00268-017-4208-zDOI Listing
April 2018

Critical appraisal of the impact of individual surgeon experience on the outcomes of laparoscopic liver resection in the modern era: collective experience of multiple surgeons at a single institution with 324 consecutive cases.

Surg Endosc 2018 04 15;32(4):1802-1811. Epub 2017 Sep 15.

Department of Hepatopancreatobiliary and Transplant Surgery, Singapore General Hospital, Level 5, 20 College Road, Academia, Singapore, 169856, Singapore.

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http://dx.doi.org/10.1007/s00464-017-5864-7DOI Listing
April 2018

Factors associated with and consequences of open conversion after laparoscopic distal pancreatectomy: initial experience at a single institution.

ANZ J Surg 2017 Dec 21;87(12):E271-E275. Epub 2016 Jul 21.

Department of Hepatopancreatobiliary and Transplantation Surgery, Singapore General Hospital, Singapore.

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http://dx.doi.org/10.1111/ans.13661DOI Listing
December 2017

Laparoscopic repeat liver resection for recurrent hepatocellular carcinoma.

ANZ J Surg 2017 Oct 27;87(10):E143-E146. Epub 2016 Apr 27.

Department of Hepatopancreatobiliary and Transplantation Surgery, Singapore General Hospital, Singapore.

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http://dx.doi.org/10.1111/ans.13628DOI Listing
October 2017

Prediction of Hepatocellular Carcinoma Recurrence Beyond Milan Criteria After Resection: Validation of a Clinical Risk Score in an International Cohort.

Ann Surg 2017 10;266(4):693-701

*Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY †Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY ‡Department of Surgery, Washington University School of Medicine, St. Louis, MO §Department of Surgery, Université de Montréal, Montreal, Quebec, Canada ¶Department of Surgery, Erasmus MC, University Medical Center, Rotterdam, The Netherlands ||Department of Hepatopancreatobiliary and Transplant Surgery, Singapore General Hospital, Singapore, Singapore **Division of Surgical Oncology, National Cancer Center, Singapore, Singapore.

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http://dx.doi.org/10.1097/SLA.0000000000002360DOI Listing
October 2017

Evolution of minimally invasive distal pancreatectomies at a single institution.

J Minim Access Surg 2018 Apr-Jun;14(2):140-145

Department of Hepatopancreatobiliary and Transplant Surgery, Singapore General Hospital, 169856, Singapore.

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http://dx.doi.org/10.4103/jmas.JMAS_26_17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5869974PMC
September 2017

Laparoscopic wedge resection for suspected large (≥5 cm) gastric gastrointestinal stromal tumors.

Surg Endosc 2017 05 8;31(5):2271-2279. Epub 2016 Sep 8.

Department of Upper Gastrointestinal and Bariatric Surgery, Singapore General Hospital, Singapore, Singapore.

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http://dx.doi.org/10.1007/s00464-016-5229-7DOI Listing
May 2017

Validation and comparison between current prognostication systems for pancreatic neuroendocrine neoplasms: A single-institution experience with 176 patients.

Surgery 2017 05 19;161(5):1235-1245. Epub 2017 Jan 19.

Duke-National University of Singapore Medical School, Singapore, Republic of Singapore; Division of Medical Oncology, National Cancer Centre Singapore, Singapore, Republic of Singapore.

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http://dx.doi.org/10.1016/j.surg.2016.12.001DOI Listing
May 2017

A comparison between robotic-assisted laparoscopic distal pancreatectomy versus laparoscopic distal pancreatectomy.

Int J Med Robot 2017 Mar 27;13(1). Epub 2016 Jan 27.

Department of Hepatopancreatobiliary and Transplantation Surgery, Singapore General Hospital, Singapore.

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http://dx.doi.org/10.1002/rcs.1733DOI Listing
March 2017

Review of 103 Cases of Laparoscopic Repeat Liver Resection for Recurrent Hepatocellular Carcinoma.

J Laparoendosc Adv Surg Tech A 2016 Nov 25;26(11):876-881. Epub 2016 Aug 25.

1 Department of Hepatopancreatobiliary and Transplantation Surgery, Singapore General Hospital , Singapore, Singapore .

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http://dx.doi.org/10.1089/lap.2016.0281DOI Listing
November 2016

Laparoscopic Liver Resection for Tumors in the Left Lateral Liver Section.

JSLS 2016 Jan-Mar;20(1)

Department of Hepatopancreatobiliary and Transplantation Surgery, Singapore General Hospital, Singapore.

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http://dx.doi.org/10.4293/JSLS.2015.00112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4744999PMC
September 2016

Blood neutrophil-to-lymphocyte and platelet-to-lymphocyte ratios are independent prognostic factors for surgically resected gastrointestinal stromal tumors.

Surgery 2016 Apr 11;159(4):1146-56. Epub 2015 Dec 11.

Department of Upper Gastrointestinal and Bariatric Surgery, Singapore General Hospital, Singapore.

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http://dx.doi.org/10.1016/j.surg.2015.10.021DOI Listing
April 2016

Robotic hepatectomy: initial experience of a single institution in Singapore.

Singapore Med J 2016 Apr 4;57(4):209-14. Epub 2016 Feb 4.

Department of Hepatopancreatobiliary and Transplantation Surgery, Singapore General Hospital, Singapore.

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http://dx.doi.org/10.11622/smedj.2016024DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4853489PMC
April 2016

Response to LTE regarding-Importance of tumor size as a prognostic factor after partial liver resection for solitary hepatocellular carcinoma: Implications on the current AJCC staging system.

J Surg Oncol 2016 Apr;113(5):594

Department of Hepatopancreatobiliary and Transplantation, Singapore General Hospital, Singapore.

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http://dx.doi.org/10.1002/jso.24172DOI Listing
April 2016

Importance of tumor size as a prognostic factor after partial liver resection for solitary hepatocellular carcinoma: Implications on the current AJCC staging system.

J Surg Oncol 2016 Jan 26;113(1):89-93. Epub 2015 Nov 26.

Department of Hepatopancreatobiliary and Transplantation Surgery, Singapore General Hospital, Singapore, Singapore.

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http://dx.doi.org/10.1002/jso.24099DOI Listing
January 2016

Laparoscopic liver resection for posterosuperior and anterolateral lesions-a comparison experience in an Asian centre.

Hepatobiliary Surg Nutr 2015 Dec;4(6):379-90

1 Department of Hepatopancreatobiliary and Transplantation Surgery, Singapore General Hospital, Singapore ; 2 Duke-NUS Graduate Medical School, Singapore ; 3 Division of Surgical Oncology, National Cancer Center Singapore, Singapore ; 4 Office of Clinical Sciences, Duke-NUS Graduate Medical School, Singapore.

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http://dx.doi.org/10.3978/j.issn.2304-3881.2015.06.06DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4689685PMC
December 2015

Methylation profiles reveal distinct subgroup of hepatocellular carcinoma patients with poor prognosis.

PLoS One 2014 5;9(8):e104158. Epub 2014 Aug 5.

Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore; Division of Medical Sciences, Humphrey Oei Institute of Cancer Research, National Cancer Centre Singapore, Singapore, Singapore; NUS Graduate School for Integrative Sciences and Engineering, National University of Singapore, Singapore, Singapore; Duke-NUS Graduate Medical School, Singapore, Singapore.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0104158PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4122406PMC
November 2015

Factors associated with and outcomes of open conversion after laparoscopic minor hepatectomy: initial experience at a single institution.

Surg Endosc 2015 Sep 27;29(9):2636-42. Epub 2014 Nov 27.

Department of Hepatopancreatobiliary and Transplantation Surgery, Singapore General Hospital, 20 College Road, Academia, Singapore, 169856, Singapore,

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http://dx.doi.org/10.1007/s00464-014-3981-0DOI Listing
September 2015

Paracrine factors of human fetal MSCs inhibit liver cancer growth through reduced activation of IGF-1R/PI3K/Akt signaling.

Mol Ther 2015 Apr 26;23(4):746-56. Epub 2015 Jan 26.

1] Division of Cellular and Molecular Research, National Cancer Centre, Singapore [2] Cancer and Stem Cell Biology Program, Duke-NUS Medical School, Singapore [3] Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.

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http://dx.doi.org/10.1038/mt.2015.13DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4395781PMC
April 2015

Evaluation of the Sendai and 2012 International Consensus Guidelines based on cross-sectional imaging findings performed for the initial triage of mucinous cystic lesions of the pancreas: a single institution experience with 114 surgically treated patients.

Am J Surg 2014 Aug 17;208(2):202-9. Epub 2014 Jan 17.

Department of Hepatopancreatobiliary and Transplantation Surgery, Division of Surgery, Singapore General Hospital, Outram Road, Singapore 169608, Singapore; Duke-NUS Graduate Medical School, 8 College Road, Singapore 169857, Singapore.

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http://dx.doi.org/10.1016/j.amjsurg.2013.09.031DOI Listing
August 2014

Number of nodules, Child-Pugh status, margin positivity, and microvascular invasion, but not tumor size, are prognostic factors of survival after liver resection for multifocal hepatocellular carcinoma.

J Gastrointest Surg 2014 Aug 23;18(8):1477-85. Epub 2014 May 23.

Department of Hepatopancreatobiliary and Transplantation Surgery, Singapore General Hospital, 20 College Road, Academia, Singapore, 169856, Singapore,

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http://dx.doi.org/10.1007/s11605-014-2542-0DOI Listing
August 2014

Utility of the sendai consensus guidelines for branch-duct intraductal papillary mucinous neoplasms: a systematic review.

J Gastrointest Surg 2014 Jul 26;18(7):1350-7. Epub 2014 Mar 26.

Department of Hepatopancreatobiliary and Transplantation Surgery, Singapore General Hospital, 20 College Road, Academia, 169856, Singapore,

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http://dx.doi.org/10.1007/s11605-014-2510-8DOI Listing
July 2014

MicroRNA-224 targets SMAD family member 4 to promote cell proliferation and negatively influence patient survival.

PLoS One 2013 29;8(7):e68744. Epub 2013 Jul 29.

Division of Medical Sciences, Humphrey Oei Institute of Cancer Research, National Cancer Centre Singapore, Singapore, Singapore.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0068744PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3726696PMC
February 2014

Altered binding site selection of p53 transcription cassettes by hepatitis B virus X protein.

Mol Cell Biol 2013 Feb 12;33(3):485-97. Epub 2012 Nov 12.

NUS Graduate School for Integrative Sciences and Engineering, National University of Singapore, Singapore, Singapore.

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http://dx.doi.org/10.1128/MCB.01189-12DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3554210PMC
February 2013

De Garengeot's hernia: an unusual right groin mass due to acute appendicitis in an incarcerated femoral hernia.

Hong Kong Med J 2012 Oct;18(5):442-5

Department of Diagnostic Radiology, Singapore General Hospital, Outram Road, Singapore.

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October 2012

MicroRNA-224 is up-regulated in hepatocellular carcinoma through epigenetic mechanisms.

FASEB J 2012 Jul 29;26(7):3032-41. Epub 2012 Mar 29.

Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.

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http://dx.doi.org/10.1096/fj.11-201855DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3382089PMC
July 2012

Atypical enhancement pattern of hepatocellular carcinoma with portal vein thrombosis on multiphasic CT.

Ann Acad Med Singapore 2011 Oct;40(10):454-9

Department of Diagnostic Radiology, Tan Tock Seng Hospital, Singapore.

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October 2011

Liver transplantation in an adult with citrullinaemia type 2.

J Transplant 2011 10;2011:176370. Epub 2011 May 10.

Liver Transplant Service, Department of Gastroenterology and Hepatology, Singapore General Hospital, Singapore 169608.

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http://dx.doi.org/10.1155/2011/176370DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3103874PMC
July 2011

Unexplained small-bowel obstruction in a patient with presumptive achalasia: need for early recognition of chronic intestinal pseudo-obstruction (CIPO).

Dig Dis Sci 2010 Sep 1;55(9):2691-2. Epub 2009 Dec 1.

Division of Gastroenterology, Changi General Hospital, 2 Simei Street 3, Singapore, 529889, Singapore.

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http://dx.doi.org/10.1007/s10620-009-1048-1DOI Listing
September 2010

Lethal-7 is down-regulated by the hepatitis B virus x protein and targets signal transducer and activator of transcription 3.

J Hepatol 2010 Jul 2;53(1):57-66. Epub 2010 Apr 2.

Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.

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http://linkinghub.elsevier.com/retrieve/pii/S016882781000186
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http://dx.doi.org/10.1016/j.jhep.2009.12.043DOI Listing
July 2010

Pancreaticoduodenectomy for locally advanced stomach cancer: preliminary results.

ANZ J Surg 2008 Sep;78(9):767-70

General Surgery, Singapore General Hospital, Singapore.

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http://dx.doi.org/10.1111/j.1445-2197.2008.04646.xDOI Listing
September 2008

Enterolith formation in the roux limb hepaticojejunostomy.

Dig Dis Sci 2007 Nov;52(11):3214-6

Department of General Surgery, Singapore General Hospital, Singapore 169608, Singapore.

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http://link.springer.com/10.1007/s10620-006-9097-1
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http://dx.doi.org/10.1007/s10620-006-9097-1DOI Listing
November 2007

Ovarian carcinoma presenting with isolated contralateral inguinal lymph node metastasis: a case report.

Ann Acad Med Singapore 2007 Jun;36(6):427-30

Department of Gastroenterology, Singapore General Hospital, Singapore.

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June 2007

Image-guided radiofrequency ablation of liver malignancies: experience at Singapore General Hospital.

Ann Acad Med Singapore 2006 Dec;35(12):851-7

Department of Diagnostic Radiology, Singapore General Hospital, Singapore.

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December 2006

Adult choledochal cysts: an audit of surgical management.

ANZ J Surg 2006 Nov;76(11):981-6

Department of Surgery, Singapore General Hospital, Singapore.

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http://dx.doi.org/10.1111/j.1445-2197.2006.03915.xDOI Listing
November 2006

Infected pancreatic necrosis--an evaluation of the timing and technique of necrosectomy in a Southeast Asian population.

Ann Acad Med Singapore 2006 Aug;35(8):523-30

Department of General Surgery, Singapore General Hospital, Singapore.

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August 2006

Factors affecting early mortality in spontaneous rupture of hepatocellular carcinoma.

ANZ J Surg 2006 Jun;76(6):448-52

Hepatopancreaticobiliary Unit, Department of General Surgery, Singapore General Hospital, Singapore.

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http://dx.doi.org/10.1111/j.1445-2197.2006.03750.xDOI Listing
June 2006

Ruptured peripheral cholangiocarcinoma with hemoperitoneum.

Dig Dis Sci 2006 May 14;51(5):874-6. Epub 2006 Jun 14.

Department of General Surgery, Singapore General Hospital, Singapore, 169608, Singapore.

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http://dx.doi.org/10.1007/s10620-006-9342-7DOI Listing
May 2006

Mucosal repair of posterior perforation of duodenal diverticulitis using roux loop duodenojejunostomy.

Asian J Surg 2005 Apr;28(2):139-41

Department of General Surgery, Singapore General Hospital, Singapore.

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April 2005

Intrahepatic biliary cystadenoma presenting with obstructive jaundice.

Asian J Surg 2004 Jul;27(3):243-5

Department of General Surgery, Singapore General Hospital, Singapore.

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http://dx.doi.org/10.1016/S1015-9584(09)60043-9DOI Listing
July 2004

Strongyloides colitis in a patient with Cushing's syndrome.

Gastrointest Endosc 2004 May;59(6):738-41

Department of General Surgery, Singapore General Hospital, Singapore.

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http://dx.doi.org/10.1016/s0016-5107(04)00289-5DOI Listing
May 2004

Outcomes of emergency common bile duct exploration: impact of preoperative endoscopic decompression.

ANZ J Surg 2003 Jun;73(6):376-80

Department of General Surgery, Singapore General Hospital, Singapore.

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June 2003

Hepatic angiomyolipoma mimicking hepatocellular carcinoma.

Asian J Surg 2002 Jul;25(3):251-4

Department of General Surgery, Singapore General Hospital, Singapore.

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http://dx.doi.org/10.1016/S1015-9584(09)60186-XDOI Listing
July 2002