Alexander U Brandt

Alexander U Brandt

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Diagnostic procedures in suspected attacks in patients with neuromyelitis optica spectrum disorders: Results of an international survey.

Mult Scler Relat Disord 2020 Feb 29;41:102027. Epub 2020 Feb 29.

Experimental and Clinical Research Center, Max Delbrueck Center for Molecular Medicine and Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany; NeuroCure Clinical Research Center, Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany; Department of Neurology, University of California, Irvine, CA, United States.

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http://dx.doi.org/10.1016/j.msard.2020.102027DOI Listing
February 2020

Longitudinal optic neuritis-unrelated visual evoked potential changes in NMO spectrum disorders.

Neurology 2020 01 3;94(4):e407-e418. Epub 2019 Dec 3.

From the Department of Neurology, Medical Faculty (M.R., J. Harmel, J.G., H.-P.H., O.A., P.A.), and Department of Neurology, Center for Neurology and Neuropsychiatry, LVR-Klinikum (M.R.), Heinrich Heine University Düsseldorf; NeuroCure Clinical Research Center and Experimental and Clinical Research Center (H.Z., A.U.B., F.P.), Charité Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, Berlin Institute of Health, and Max Delbrueck Center for Molecular Medicine, Germany; Department of Neurology (A.U.B.), University of California Irvine; Department of Neurology (A.H., M.B.), University of Würzburg; Department of Neurology (M.B.), Caritas Hospital, Bad Mergentheim; Clinical Neuroimmunology and Neurochemistry (M.W.H.), Department of Neurology (C.T.), Hannover Medical School; Department of Neurology (C.S., I.A., I.K., K.H.), St. Josef Hospital, Ruhr University Bochum, Germany; Department of Neurology (I.A.), Sechenov First Moscow State Medical University, Moscow, Russia; Marianne-Strauß-Klinik (I.K.), Behandlungszentrum Kempfenhausen für Multiple Sklerose Kranke, Berg; Institute of Clinical Neuroimmunology (J. Halva, T.K., H.P.), University Hospital, Ludwig-Maximilians University, Munich; Molecular Neuroimmunology Group, Department of Neurology (S.J., B.W.), University of Heidelberg, Germany; Department of Neurology (P.R.), Medical University of Vienna, Austria; Institute of Neuropathology (M.S.W.) and Department of Neurology (M.S.W., H.P., P.K.), University Medical Center Göttingen; Department of Neurology (L.R., C.G.), Jena University Hospital; Neuroimmunological Section, Department of Neurology (N.R., U.Z.), University of Rostock; Department of Neurology (M.D., L.K.), University of Münster; Department of Neurology and Institute of Neuroimmunology and MS (K.Y., J.-P.S.), University Medical Center Hamburg-Eppendorf; Department of Neurology (M.K., P.K.), Nordwest-Hospital Sanderbusch, Sande; Department of Neurology (W.M.), Helios Hanseklinikum Stralsund; Department of Neurology (F.L., H.T.), University of Ulm, Germany; and Faculty of Medicine and Health Sciences (A.K.), Macquarie University, Sydney, New South Wales, Australia.

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http://dx.doi.org/10.1212/WNL.0000000000008684DOI Listing
January 2020

High-dose vitamin D supplementation in multiple sclerosis - results from the randomized EVIDIMS (efficacy of vitamin D supplementation in multiple sclerosis) trial.

Mult Scler J Exp Transl Clin 2020 Jan-Mar;6(1):2055217320903474. Epub 2020 Jan 24.

Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, NeuroCure Clinical Research Center, Germany.

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http://dx.doi.org/10.1177/2055217320903474DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6984434PMC
January 2020

Prodromal headache in MOG-antibody positive optic neuritis.

Mult Scler Relat Disord 2020 Jan 25;40:101965. Epub 2020 Jan 25.

Nuffield Department of Clinical Neurosciences, Level 6, West Wing, John Radcliffe Hospital, Oxford, OX3 9DU, UK.

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http://dx.doi.org/10.1016/j.msard.2020.101965DOI Listing
January 2020

Spinal cord lesions and atrophy in NMOSD with AQP4-IgG and MOG-IgG associated autoimmunity.

Mult Scler 2019 12 26;25(14):1926-1936. Epub 2018 Nov 26.

NeuroCure Clinical Research Center, Charité - Universitätsmedizin Berlin, Berlin, Germany/Department of Neurology, University of California, Irvine, CA, USA.

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http://journals.sagepub.com/doi/10.1177/1352458518815596
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http://dx.doi.org/10.1177/1352458518815596DOI Listing
December 2019

Contactless recording of sleep apnea and periodic leg movements by nocturnal 3-D-video and subsequent visual perceptive computing.

Sci Rep 2019 Nov 14;9(1):16812. Epub 2019 Nov 14.

Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Interdisciplinary Center of Sleep Medicine, Berlin, Germany.

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http://dx.doi.org/10.1038/s41598-019-53050-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6856090PMC
November 2019

Intrathecal IgM production is a strong risk factor for early conversion to multiple sclerosis.

Neurology 2019 10 9;93(15):e1439-e1451. Epub 2019 Sep 9.

From the Department of Neurology (C.P., J.R.B., F.C.P., R.W., F.P., K.R., J.O.), NeuroCure Clinical Research Center (C.P., R.M.G., M.S., J.R.B., L.R., F.C.P., A.U.B., J.B.-S., F.P.), Institute for Biometry and Clinical Epidemiology (U.G.), and Department of Neuroradiology (M.S.), Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health (U.G.), Berlin; Department of Neurology (A.U.B.), University of California Irvine; Experimental and Clinical Research Center (J.B.-S., F.P.), Charité-Universitätsmedizin Berlin and Max Delbrück Center for Molecular Medicine, Berlin-Buch, Germany; and Neurological Clinic and Policlinic (J.O.), Basel University Hospital, Basel, Switzerland.

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http://dx.doi.org/10.1212/WNL.0000000000008237DOI Listing
October 2019

Uncovering convolutional neural network decisions for diagnosing multiple sclerosis on conventional MRI using layer-wise relevance propagation.

Neuroimage Clin 2019 6;24:102003. Epub 2019 Sep 6.

Charité - Universitätsmedizin Berlin, Freie Universität Berlin, Humboldt-Universität zu Berlin, Berlin Institute of Health (BIH), Department of Psychiatry and Psychotherapy, 10117 Berlin, Germany; Charité - Universitätsmedizin Berlin, Freie Universität Berlin, Humboldt-Universität zu Berlin, Berlin Institute of Health (BIH), Berlin Center for Advanced Neuroimaging, Bernstein Center for Computational Neuroscience, 10117 Berlin, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.nicl.2019.102003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6807560PMC
September 2019

Neural mechanisms of perceptual decision-making and their link to neuropsychiatric symptoms in multiple sclerosis.

Mult Scler Relat Disord 2019 Aug 30;33:139-145. Epub 2019 May 30.

Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Excellence Cluster NeuroCure, Berlin 10117, Germany; Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Clinical and Experimental Multiple Sclerosis Research Center, Department of Neurology, Berlin 10117, Germany; Experimental and Clinical Research Center, Max Delbrueck Center for Molecular Medicine and Charité - Universitätsmedizin Berlin, Berlin 13125, Germany.

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http://dx.doi.org/10.1016/j.msard.2019.05.025DOI Listing
August 2019

Quantitative grip force assessment of muscular weakness in chronic inflammatory demyelinating polyneuropathy.

BMC Neurol 2019 Jun 8;19(1):118. Epub 2019 Jun 8.

NeuroCure Clinical Research Center, Charité - University Medicine Berlin, Charitéplatz 1, 10117, Berlin, Germany.

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http://dx.doi.org/10.1186/s12883-019-1339-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6556046PMC
June 2019

Cognitive Impairment in Neuromyelitis Optica Spectrum Disorders: A Review of Clinical and Neuroradiological Features.

Front Neurol 2019 12;10:608. Epub 2019 Jun 12.

NeuroCure Clinical Research Center, Berlin Institute of Health, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, Berlin, Germany.

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http://dx.doi.org/10.3389/fneur.2019.00608DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6587817PMC
June 2019

Damage of the lateral geniculate nucleus in MS: Assessing the missing node of the visual pathway.

Neurology 2019 05 10;92(19):e2240-e2249. Epub 2019 Apr 10.

From the Neurologic Clinic and Policlinic, Departments of Medicine, Clinical Research, and Biomedical Engineering (A. Papadopoulou, L.G., A. Pfister, C.T., M.H., L.K., T.S., S.M.), and Translational Imaging in Neurology (ThINK) Basel, Department of Medicine and Biomedical Engineering (A. Papadopoulou, L.G., A.A., C.T., S.M.), University Hospital Basel and University of Basel, Switzerland; NeuroCure Clinical Research Center (NCRC) (A. Papadopoulou, A.U.B.), and Experimental and Clinical Research Center (A. Papadopoulou, A.U.B.), Max Delbrück Center for Molecular Medicine, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Germany; Medical Image Analysis Center (MIAC) (L.G., A.A., C.T., S.M.), Basel, Switzerland; Imeka Solutions (F.M.), Sherbrooke, Canada; Department of Neurology (A.U.B.), University of California Irvine; Cerebral Imaging Centre (M.M.C.), Douglas Mental Health University Institute; Departments of Psychiatry and Biomedical Engineering (M.M.C.), McGill University, Montreal; University of Sherbrooke (M.D.), Canada; and Department of Neurology (T.S.), DKD Helios Klinik Wiesbaden, Germany. The present address for L.G. is F. Hoffmann-La Roche, Basel, Switzerland.

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http://dx.doi.org/10.1212/WNL.0000000000007450DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6537126PMC
May 2019

Standardization of T1w/T2w Ratio Improves Detection of Tissue Damage in Multiple Sclerosis.

Front Neurol 2019 9;10:334. Epub 2019 Apr 9.

NeuroCure Clinical Research Center, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin and Berlin Institute of Health, Berlin, Germany.

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https://www.frontiersin.org/article/10.3389/fneur.2019.00334
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http://dx.doi.org/10.3389/fneur.2019.00334DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6465519PMC
April 2019

Comparison of probabilistic tractography and tract-based spatial statistics for assessing optic radiation damage in patients with autoimmune inflammatory disorders of the central nervous system.

Neuroimage Clin 2018 8;19:538-550. Epub 2018 May 8.

Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Neurocure Cluster of Excellence, NeuroCure Clinical Research Center, NCRC Charité, Charitéplatz 1, 10117 Berlin, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.nicl.2018.05.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6029567PMC
January 2019

Novel uses of retinal imaging with optical coherence tomography in multiple sclerosis.

Expert Rev Neurother 2019 Jan 27;19(1):31-43. Epub 2018 Dec 27.

a NeuroCure Clinical Research Center , Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health , Berlin , Germany.

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http://dx.doi.org/10.1080/14737175.2019.1559051DOI Listing
January 2019

Retinal ganglion cell loss in neuromyelitis optica: a longitudinal study.

J Neurol Neurosurg Psychiatry 2018 12 19;89(12):1259-1265. Epub 2018 Jun 19.

NeuroCure Clinical Research Center, Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany.

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http://jnnp.bmj.com/lookup/doi/10.1136/jnnp-2018-318382
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http://dx.doi.org/10.1136/jnnp-2018-318382DOI Listing
December 2018

Optical coherence tomography in acute optic neuritis: A population-based study.

Acta Neurol Scand 2018 Dec 14;138(6):566-573. Epub 2018 Aug 14.

Institutes of Regional Health Research and Molecular Medicine, University of Southern Denmark, Odense, Denmark.

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http://dx.doi.org/10.1111/ane.13004DOI Listing
December 2018

The International Multiple Sclerosis Visual System Consortium: Advancing Visual System Research in Multiple Sclerosis.

J Neuroophthalmol 2018 12;38(4):494-501

Departments of Neurology, Ophthalmology & Population Health (LJ Balcer), New York University School of Medicine, New York University, New York, New York; Department of Neurology (LJ Balk, AP), Amsterdam UMC-Location VUmc, Amsterdam, the Netherlands; Department of Neurology (AUB, FP), NeuroCure Clinical Research Center and Experimental and Clinical Research Center, Charité-Universitätsmedizin Berlin and Max Delbrueck Center for Molecular Medicine, Berlin, Germany; Department of Neurology (PAC, SS), Johns Hopkins University, Baltimore, Maryland; Department of Neurology (EHM-L), Hospital Clinic of Barcelona, Institut d'Investigacions Biomèdiques August Pi Sunyer (IDIBAPS), Barcelona, Spain; Department of Population Health (RCN), Sackler Institute for Biomedical Sciences, New York University, New York, NY, USA & Department of Neurology, New York University School of Medicine, New York University, New York, New York; and Department of Neurology (AP), University College London, the National Hospital for Neurology and Neurosurgery, Moorfields Eye Hospital, London, United Kingdom.

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http://Insights.ovid.com/crossref?an=00041327-201812000-0001
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http://dx.doi.org/10.1097/WNO.0000000000000732DOI Listing
December 2018

Active contour method for ILM segmentation in ONH volume scans in retinal OCT.

Biomed Opt Express 2018 Dec 28;9(12):6497-6518. Epub 2018 Nov 28.

NeuroCure Clinical Research Center, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany.

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http://dx.doi.org/10.1364/BOE.9.006497DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6491014PMC
December 2018

[Optical Coherence Tomography in Disorders of the Central Nervous System].

Klin Monbl Augenheilkd 2018 Nov 20;235(11):1242-1258. Epub 2018 Nov 20.

NeuroCure Clinical Research Center, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany.

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http://www.thieme-connect.de/DOI/DOI?10.1055/a-0715-7961
Publisher Site
http://dx.doi.org/10.1055/a-0715-7961DOI Listing
November 2018

Temporal visual resolution and disease severity in MS.

Neurol Neuroimmunol Neuroinflamm 2018 Sep 14;5(5):e492. Epub 2018 Aug 14.

Charité-Universitätsmedizin Berlin (N.A., J.D., S.M., K.G., J.B.-S., J.M., A.U.B., H.Z., F.P.), Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, NeuroCure Clinical Research Center; Neurology Department (J.D.), Multiple Sclerosis Center, Oberhavel Clinic, Henningsdorf; Experimental and Clinical Research Center (J.B.-S., F.P.), Max Delbrueck Center for Molecular Medicine and Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health; and Department of Neurology (F.P.), Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Germany.

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http://dx.doi.org/10.1212/NXI.0000000000000492DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6117185PMC
September 2018

Brain activity, regional gray matter loss, and decision-making in multiple sclerosis.

Mult Scler 2018 08 28;24(9):1163-1173. Epub 2017 Jun 28.

Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health; Excellence Cluster NeuroCure; 10117 Berlin, Germany / Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health; Clinical and Experimental Multiple Sclerosis Research Center, Department of Neurology; 10117 Berlin, Germany / Experimental and Clinical Research Center, Max Delbrueck Center for Molecular Medicine and Charité - Universitätsmedizin Berlin, 13125 Berlin, Germany.

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http://dx.doi.org/10.1177/1352458517717089DOI Listing
August 2018

Pain in AQP4-IgG-positive and MOG-IgG-positive neuromyelitis optica spectrum disorders.

Mult Scler J Exp Transl Clin 2018 Jul-Sep;4(3):2055217318796684. Epub 2018 Aug 30.

NeuroCure Clinical Research Center, Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Germany.

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http://journals.sagepub.com/doi/10.1177/2055217318796684
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http://dx.doi.org/10.1177/2055217318796684DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6117869PMC
August 2018

MRI Markers and Functional Performance in Patients With CIS and MS: A Cross-Sectional Study.

Front Neurol 2018 29;9:718. Epub 2018 Aug 29.

NeuroCure Clinical Research Center, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, NeuroCure Cluster of Excellence, Berlin, Germany.

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https://www.frontiersin.org/article/10.3389/fneur.2018.00718
Publisher Site
http://dx.doi.org/10.3389/fneur.2018.00718DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6123531PMC
August 2018

Multicenter reliability of semiautomatic retinal layer segmentation using OCT.

Neurol Neuroimmunol Neuroinflamm 2018 May 13;5(3):e449. Epub 2018 Mar 13.

NeuroCure Clinical Research Center (T.O., F.P., A.U.B.), Charité-Universitätsmedizin Berlin, Germany; Department of Ophthalmology (G.L.T.), University Hospital Zurich, University of Zurich; Neuroimmunology and Multiple Sclerosis Research Section (S.L., S.S.), Department of Neurology, University Hospital Zurich, University of Zurich, Switzerland; Center of Neuroimmunology (I.G., P.V.), Institut d'Investigacions Biomediques August Pi Sunyer (IDIBAPS)-Hospital Clinic, Barcelona, Spain; Division of Neuroinflammation and Glial Biology (R.N., C.S., A.J.G.), Department of Neurology, University of California San Francisco; Neuro-ophthalmology Division (A.J.G.), Department of Ophthalmology, University of California, San Francisco; Multiple Sclerosis Center (L.B., A.P.), Departments of Neurology and Ophthalmology, Neuro-ophthalmology Expertise Centre, VUmc, Amsterdam and Moorfields Eye Hospital (A.P.), The National Hospital for Neurology and Neurosurgery and UCL, United Kingdom; Clinical and Experimental Multiple Sclerosis Research Center (F.P.), Department of Neurology, Charité-Universitätsmedizin Berlin; Experimental and Clinical Research Center (F.P., A.U.B.), Charité-Universitätsmedizin Berlin and Max-Delbrück Center for Molecular Medicine, Germany; Department of Methods and Experimental Psychology (I.G.), Faculty of Psychology and Education, Universidad de Deusto, Bilbao, Spain.

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http://dx.doi.org/10.1212/NXI.0000000000000449DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5852947PMC
May 2018

Frequent retinal ganglion cell damage after acute optic neuritis.

Mult Scler Relat Disord 2018 May 9;22:141-147. Epub 2018 Apr 9.

University of Calgary, Department of Clinical Neurosciences, 2500 University Dr. NW, Calgary, Alberta, Canada T2N 1N4; University of Calgary, Department of Surgery, Calgary, Alberta, Canada; Hotchkiss Brain Institute, 3330 Hospital Drive NW, Calgary, Alberta, Canada T2N 4N1.

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http://dx.doi.org/10.1016/j.msard.2018.04.006DOI Listing
May 2018

Optical coherence tomography in neuromyelitis optica spectrum disorders: potential advantages for individualized monitoring of progression and therapy.

EPMA J 2018 Mar 22;9(1):21-33. Epub 2017 Dec 22.

NeuroCure Clinical Research Center, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Charitéplatz 1, 10117 Berlin, Germany.

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http://dx.doi.org/10.1007/s13167-017-0123-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833887PMC
March 2018

Self-perception and determinants of color vision in Parkinson's disease.

J Neural Transm (Vienna) 2018 02 15;125(2):145-152. Epub 2017 Nov 15.

NeuroCure Clinical Research Center, NeuroCure Cluster of Excellence, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Charitéplatz 1, 10117, Berlin, Germany.

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http://dx.doi.org/10.1007/s00702-017-1812-xDOI Listing
February 2018

Maximum walking speed in multiple sclerosis assessed with visual perceptive computing.

PLoS One 2017 15;12(12):e0189281. Epub 2017 Dec 15.

Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, NeuroCure Cluster of Excellence, NeuroCure Clinical Research Center, Berlin, Germany.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0189281PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5731685PMC
January 2018

Safety and preliminary efficacy of deep transcranial magnetic stimulation in MS-related fatigue.

Neurol Neuroimmunol Neuroinflamm 2018 Jan 13;5(1):e423. Epub 2017 Dec 13.

NeuroCure Clinical Research Center (G.G., A.U.B., C.P., J.D., J.B.-S., S.K.P., F.P.), Center for Stroke Research Berlin (CSB) (S.K.P.), Experimental and Clinical Research Center (J.B.-S., F.P.), and Clinical and Experimental Multiple Sclerosis Research Center (F.P.), Department of Neurology, Charité-Universitätsmedizin Berlin, Germany; Institute of Neuroimmunology and Multiple Sclerosis (M.T., I.L., S.S.), University Medical Centre Hamburg-Eppendorf, Germany; Department of Life Sciences (Y.R., A.Z.), Ben-Gurion University, Beer-Sheva, Israel; and Max-Delbrück Center for Molecular Medicine (F.P.), Berlin, Germany. G.G. and C.P. are now with St. Joseph Krankenhaus-Berlin-Weissensee, Germany. S.S. is now with Neuroimmunology and Multiple Sclerosis Research, Department of Neurology, University Hospital Zurich and University of Zurich, Switzerland.

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http://dx.doi.org/10.1212/NXI.0000000000000423DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5730816PMC
January 2018

Patients with multiple sclerosis demonstrate reduced subbasal corneal nerve fibre density.

Mult Scler 2017 Dec 3;23(14):1847-1853. Epub 2016 Nov 3.

NeuroCure Clinical Research Center and Clinical and Experimental Multiple Sclerosis Research Center, Charité - Universitätsmedizin Berlin, Berlin, Germany.

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http://dx.doi.org/10.1177/1352458516677590DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5513781PMC
December 2017

Patient perspectives on neuromyelitis optica spectrum disorders: Data from the PatientsLikeMe online community.

Mult Scler Relat Disord 2017 Oct 11;17:116-122. Epub 2017 Jul 11.

PatientsLikeMe Inc., 160 s Street, Cambridge, MA 02142, USA. Electronic address:

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http://dx.doi.org/10.1016/j.msard.2017.07.014DOI Listing
October 2017

CuBe: parametric modeling of 3D foveal shape using cubic Bézier.

Biomed Opt Express 2017 Sep 22;8(9):4181-4199. Epub 2017 Aug 22.

NeuroCure Clinical Research Center, Charité - Universitätsmedizin Berlin, Germany.

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http://dx.doi.org/10.1364/BOE.8.004181DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5611933PMC
September 2017

Diffusion tensor imaging for multilevel assessment of the visual pathway: possibilities for personalized outcome prediction in autoimmune disorders of the central nervous system.

EPMA J 2017 Sep 25;8(3):279-294. Epub 2017 Jul 25.

Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Neurocure Cluster of Excellence, NeuroCure Clinical Research Center, Charitéplatz 1, D-10117 Berlin, Germany.

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http://dx.doi.org/10.1007/s13167-017-0102-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5607151PMC
September 2017

Single-subject independent component analysis-based intensity normalization in non-quantitative multi-modal structural MRI.

Hum Brain Mapp 2017 Jul 22;38(7):3615-3622. Epub 2017 Apr 22.

NeuroCure Clinical Research Center, NeuroCure Cluster of Excellence, Charité - Universitätsmedizin Berlin, Berlin, Germany.

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http://dx.doi.org/10.1002/hbm.23615DOI Listing
July 2017

Optical coherence tomography for the diagnosis and monitoring of idiopathic intracranial hypertension.

J Neurol 2017 Jul 5;264(7):1370-1380. Epub 2017 Jun 5.

Focus Program Translational Neuroscience (FTN), Rhine Main Neuroscience Network (RMN(2)), Department of Neurology, Johannes Gutenberg University Medical Center, Mainz, Germany.

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http://dx.doi.org/10.1007/s00415-017-8532-xDOI Listing
July 2017

Gadopentetate but not gadobutrol accumulates in the dentate nucleus of multiple sclerosis patients.

Mult Scler 2017 Jun 27;23(7):963-972. Epub 2016 Sep 27.

NeuroCure Clinical Research Center, NeuroCure Cluster of Excellence, Charité - Universitätsmedizin Berlin, Berlin, Germany.

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June 2017

Accuracy and Reliability of the Kinect Version 2 for Clinical Measurement of Motor Function.

PLoS One 2016 18;11(11):e0166532. Epub 2016 Nov 18.

NeuroCure Clinical Research Center and Clinical and Experimental Multiple Sclerosis Research Center, Charité - Universitätsmedizin Berlin, Berlin, Germany.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5115766PMC
June 2017

Microstructural visual system changes in AQP4-antibody-seropositive NMOSD.

Neurol Neuroimmunol Neuroinflamm 2017 May 22;4(3):e334. Epub 2017 Feb 22.

NeuroCure Clinical Research Center (F.C.O., J.K., H.Z., C.C., F.S., J.B.-S., M.S., F.P., A.U.B.), and Department of Neurology (J.K., F.S., J.B.-S., K.R., F.P.), Charité-Universitätsmedizin Berlin; Department of Neurology (B.K., T.K.), Klinikum rechts der Isar, and Department of Experimental Neuroimmunology (T.K.), Technische Universität München; Munich Cluster for Systems Neurology (SyNergy) (T.K.), Germany; Clinical Ophthalmology and Eye Health (A.K.), Central Clinical School, Save Sight Institute, Sydney, Australia; and Experimental and Clinical Research Center (F.P.), Max Delbrueck Center for Molecular Medicine and Charité-Universitätsmedizin Berlin, Germany.

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http://nn.neurology.org/lookup/doi/10.1212/NXI.0000000000000
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http://dx.doi.org/10.1212/NXI.0000000000000334DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5322864PMC
May 2017

Contribution of blood vessels to retinal nerve fiber layer thickness in NMOSD.

Neurol Neuroimmunol Neuroinflamm 2017 May 18;4(3):e338. Epub 2017 Apr 18.

NeuroCure Clinical Research Center (F.C.O., H.Z., J.M., M.W., E.M.K., T.O., F. Pache, J.B.-S., F. Paul, A.U.B.), Department of Neurology (F. Pache, J.B.-S., K.R., F. Paul), Charité-Universitätsmedizin Berlin; and Experimental and Clinical Research Center (J.B.-S., F. Paul), Max Delbrueck Center for Molecular Medicine and Charité-Universitätsmedizin Berlin, Germany.

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http://dx.doi.org/10.1212/NXI.0000000000000338DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5398419PMC
May 2017

Monitoring the Course of MS With Optical Coherence Tomography.

Curr Treat Options Neurol 2017 Apr;19(4):15

Johns Hopkins University, Baltimore, MD, USA.

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http://link.springer.com/10.1007/s11940-017-0452-7
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http://dx.doi.org/10.1007/s11940-017-0452-7DOI Listing
April 2017

Whole-body positional manipulators for ocular imaging of anaesthetised mice and rats: a do-it-yourself guide.

BMJ Open Ophthalmol 2017 6;1(1):e000008. Epub 2016 Nov 6.

Department of Neurology, Heinrich-Heine-Universität Düsseldorf, Düsseldorf, Germany.

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http://dx.doi.org/10.1136/bmjophth-2016-000008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5759402PMC
November 2016

Characterizing the phenotype of multiple sclerosis-associated depression in comparison with idiopathic major depression.

Mult Scler 2016 10 8;22(11):1476-1484. Epub 2016 Jan 8.

Department of Psychiatry and Psychotherapy, Charité-Universitätsmedizin Berlin, Campus Benjamin Franklin, Berlin, Germany/Institute of Neuroimmunology and Multiple Sclerosis (INIMS), University Medical Center Hamburg-Eppendorf, Hamburg, Germany

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http://dx.doi.org/10.1177/1352458515622826DOI Listing
October 2016

Validity of visual perceptive computing for static posturography in patients with multiple sclerosis.

Mult Scler 2016 10 26;22(12):1596-1606. Epub 2016 Jan 26.

NeuroCure Clinical Research Center, Charité - Universitätsmedizin Berlin, Berlin, Germany/Department of Neurology, Charité - Universitätsmedizin Berlin, Berlin, Germany.

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http://dx.doi.org/10.1177/1352458515625807DOI Listing
October 2016

Accuracy and repeatability of two methods of gait analysis - GaitRite™ und Mobility Lab™ - in subjects with cerebellar ataxia.

Gait Posture 2016 07 25;48:194-201. Epub 2016 May 25.

Department of Neurology, Charité - Universitätsmedizin Berlin, Augustenburger Platz 1, 13353 Berlin, Germany.

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http://dx.doi.org/10.1016/j.gaitpost.2016.05.014DOI Listing
July 2016

Normal volumes and microstructural integrity of deep gray matter structures in AQP4+ NMOSD.

Neurol Neuroimmunol Neuroinflamm 2016 Jun 20;3(3):e229. Epub 2016 Apr 20.

Department of Neurology (C.F., J.H., F. Pache, N.B., K.R., F. Paul) and NeuroCure Clinical Research Center NCRC (F. Pache, A.L., N.B., J.K., J.B.-S., A.U.B., F. Paul), Charité-Universitätsmedizin Berlin; Berlin School of Mind and Brain (C.F.), Humboldt-Universität zu Berlin; and Experimental and Clinical Research Center (J.B.-S., F. Paul), Max Delbrueck Center for Molecular Medicine and Charité-Universitätsmedizin Berlin, Germany.

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http://dx.doi.org/10.1212/NXI.0000000000000229DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4841641PMC
June 2016

The APOSTEL recommendations for reporting quantitative optical coherence tomography studies.

Neurology 2016 Jun 25;86(24):2303-9. Epub 2016 May 25.

From the Multiple Sclerosis Center (A.C.-H., P.V., A.J.G.), Department of Neurology, University of California San Francisco; Departments of Neurology and Ophthalmology (L.J.B., A.P.), VU University Medical Centre, Amsterdam, the Netherlands; Charité-Universitätsmedizin Berlin (T.O., F.P., A.U.B.), NeuroCure Clinical Research Center; Department of Neurology (T.O., F.P., A.U.B.), Experimental and Clinical Research Center, Max Delbrueck Center for Molecular Medicine, Berlin, Germany; Department of Neurology (S.S., P.C.), Johns Hopkins University, Baltimore, MD; Center of Neuroimmunology and Department of Neurology (E.H.M.-L., P.V.), Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Hospital Clinic of Barcelona, Spain; Eye Center (W.A.L.), University Medical Center, Freiburg, Germany; Departments of Ophthalmology (J.S.S.) and Neurology (L.B.), New York University School of Medicine, New York; Moorfields Eye Hospital and The National Hospital for Neurology and Neurosurgery (A.P.), London, UK; and Department of Neurology (P.A.), Medical Faculty, Heinrich-Heine University Düsseldorf, Germany.

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http://dx.doi.org/10.1212/WNL.0000000000002774DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4909557PMC
June 2016

Visual dysfunction, but not retinal thinning, following anti-NMDA receptor encephalitis.

Neurol Neuroimmunol Neuroinflamm 2016 Apr 2;3(2):e198. Epub 2016 Feb 2.

NeuroCure Clinical Research Center (A.U.B., T.O., J.M., H.Z., F.P.) and Department of Neurology (H.P., F.P., C.F.), Charité-Universitätsmedizin Berlin; German Center for Neurodegenerative Diseases (DZNE) (H.P.), Berlin; and Berlin School of Mind and Brain (C.F.), Humboldt-Universität zu Berlin, Germany.

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http://dx.doi.org/10.1212/NXI.0000000000000198DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4747477PMC
April 2016

RETINAL LESION EVOLUTION IN SUSAC SYNDROME.

Retina 2016 Feb;36(2):366-74

*NeuroCure Clinical Research Center, Charité-Universitätsmedizin Berlin, Berlin, Germany; †Departments of Clinical Neurosciences, and ‡Surgery, University of Calgary, Calgary, Alberta, Canada; §Calgary Retina Consultants, University of Calgary, Calgary, Alberta, Canada; ¶Department of Neurology, Charité-Universitätsmedizin Berlin, Berlin, Germany; **Department of Neurology, University of Münster, Münster, Germany; and ††Department of Ophthalmology, Charité-Universitätsmedizin Berlin, Berlin, Germany.

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http://dx.doi.org/10.1097/IAE.0000000000000700DOI Listing
February 2016

Quantitative motor assessment of muscular weakness in myasthenia gravis: a pilot study.

BMC Neurol 2015 Dec 23;15:265. Epub 2015 Dec 23.

NeuroCure Clinical Research Center, Charité - Universitätsmedizin Berlin, Charitéplatz 1, 10117, Berlin, Germany.

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http://dx.doi.org/10.1186/s12883-015-0517-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4690227PMC
December 2015

Axonal damage in papilledema linked to idiopathic intracranial hypertension as revealed by multifocal visual evoked potentials.

Clin Neurophysiol 2015 Oct 27;126(10):2040-1. Epub 2014 Dec 27.

Department of Neurology, Medical Faculty, Heinrich-Heine University, Düsseldorf, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.clinph.2014.12.014DOI Listing
October 2015

Temporal retinal nerve fibre layer thinning in cluster headache patients detected by optical coherence tomography.

Cephalalgia 2015 Oct 5;35(11):946-58. Epub 2015 Feb 5.

Department of Neurology, University Hospital of Münster, Germany Department of Neurology, kbo Isar-Amper-Klinikum, München-Ost, Germany

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http://dx.doi.org/10.1177/0333102414560632DOI Listing
October 2015

Comparison of Standard Versus Wide-Field Composite Images of the Corneal Subbasal Layer by In Vivo Confocal Microscopy.

Invest Ophthalmol Vis Sci 2015 Sep;56(10):5801-7

Ocular Surface Imaging Center, Cornea and Refractive Surgery Service, Massachusetts Eye and Ear Infirmary, Department of Ophthalmology, Harvard Medical School, Boston, Massachusetts, United States 2Boston Image Reading Center, Cornea Service, New England.

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http://dx.doi.org/10.1167/iovs.15-17434DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4559214PMC
September 2015

Retinal pathology in idiopathic moyamoya angiopathy detected by optical coherence tomography.

Neurology 2015 Aug 15;85(6):521-7. Epub 2015 Jul 15.

From the Departments of Neurology (P.A., C.B., M.R., A.-K.M., J.H., O.A., H.-P.H.) and Ophthalmology (D.F., R.G.), Medical Faculty, Heinrich Heine University Düsseldorf, Germany; Neurology Clinic (S.L.), Department of Clinical Neuroimmunology and Multiple Sclerosis Research, University Medical Center Zürich, Switzerland; Charité-Universitätsmedizin Berlin (E.-M.K., F.P., A.U.B.), NeuroCure Clinical Research Center and Department of Neurology, Berlin; Department of Neurology (A.M.), University Medical Center, Johannes Gutenberg University Mainz; and Department of Neurology (P.B., M.K.), Alfried Krupp Hospital, Essen, Germany.

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http://dx.doi.org/10.1212/WNL.0000000000001832DOI Listing
August 2015

Cross-recognition of a myelin peptide by CD8+ T cells in the CNS is not sufficient to promote neuronal damage.

J Neurosci 2015 Mar;35(12):4837-50

Department of Neurology, Research Center Translational Neurosciences, Rhine Main Neuroscience Network (rmn), and Molecular Neurology Group, Max Delbrueck Center for Molecular Medicine Berlin-Buch, 13125 Berlin, Germany, Charité University Medicine Berlin, ECRC, 13125 Berlin, Germany, and

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http://dx.doi.org/10.1523/JNEUROSCI.3380-14.2015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6705380PMC
March 2015

Author response.

Neurology 2015 Jan;84(4):437

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January 2015

Re: Garcia-Martin et al.: Retinal layer segmentation in patients with multiple sclerosis using spectral domain optical coherence tomography (Ophthalmology 2014;121:573-9).

Ophthalmology 2014 Nov 24;121(11):e63. Epub 2014 Oct 24.

Department of Neurology, Medical Faculty, Heinrich-Heine University Düsseldorf, Germany.

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http://dx.doi.org/10.1016/j.ophtha.2014.06.018DOI Listing
November 2014

Reply: photoreceptor layer thinning is not specific for Parkinson's disease.

Mov Disord 2014 Sep 1;29(10):1332. Epub 2014 Jul 1.

NeuroCure Clinical Research Center, Charité - Universitätsmedizin Berlin, Germany.

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http://dx.doi.org/10.1002/mds.25957DOI Listing
September 2014

Photoreceptor layer thinning in idiopathic Parkinson's disease.

Mov Disord 2014 Aug 30;29(9):1163-70. Epub 2014 Apr 30.

NeuroCure Clinical Research Center, Charité-Universitätsmedizin Berlin, Germany.

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http://dx.doi.org/10.1002/mds.25896DOI Listing
August 2014

Reply to: photoreceptor layer thinning in Parkinsonian syndromes.

Mov Disord 2014 Aug 7;29(9):1223-4. Epub 2014 Jun 7.

NeuroCure Clinical Research Center, Charité-Universitätsmedizin Berlin, Germany.

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http://dx.doi.org/10.1002/mds.25936DOI Listing
August 2014

Dynamic formation of macular microcysts independent of vitreous traction changes.

Neurology 2014 Jul 23;83(1):73-7. Epub 2014 May 23.

From the NeuroCure Clinical Research Center (A.U.B., T.O., E.M.K., F.P.), and Clinical and Experimental Multiple Sclerosis Research Center, Department of Neurology (F.P.), Charité-Universitätsmedizin Berlin; and University Eye Hospital Freiburg (W.A.L.), Germany.

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http://dx.doi.org/10.1212/WNL.0000000000000545DOI Listing
July 2014

Using perceptive computing in multiple sclerosis - the Short Maximum Speed Walk test.

J Neuroeng Rehabil 2014 May 27;11:89. Epub 2014 May 27.

NeuroCure Clinical Research Center, Charité - Universitätsmedizin Berlin, Charitéplatz 1, 10117 Berlin, Germany.

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http://dx.doi.org/10.1186/1743-0003-11-89DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4041903PMC
May 2014

Optic neuritis is associated with inner nuclear layer thickening and microcystic macular edema independently of multiple sclerosis.

PLoS One 2013 6;8(8):e71145. Epub 2013 Aug 6.

NeuroCure Clinical Research Center and Experimental and Clinical Research Center, Charité-Universitätsmedizin Berlin and Max Delbrück Center for Molecular Medicine, Berlin, Germany.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0071145PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3735514PMC
April 2014

Metabolic evidence for cerebral neurodegeneration in spinocerebellar ataxia type 1.

Cerebellum 2014 Apr;13(2):199-206

Department of Neurology, Charité-Universitätsmedizin Berlin, Charitéplatz 1, 10117, Berlin, Germany,

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http://link.springer.com/10.1007/s12311-013-0527-2
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http://dx.doi.org/10.1007/s12311-013-0527-2DOI Listing
April 2014

Relations of low contrast visual acuity, quality of life and multiple sclerosis functional composite: a cross-sectional analysis.

BMC Neurol 2014 Feb 20;14:31. Epub 2014 Feb 20.

NeuroCure Clinical Research Center, Charité - Universitätsmedizin Berlin, Charitéplatz 1, 10117 Berlin, Germany.

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http://dx.doi.org/10.1186/1471-2377-14-31DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3932139PMC
February 2014

Retinal ganglion cell and inner plexiform layer thinning in clinically isolated syndrome.

Mult Scler 2013 Dec 23;19(14):1887-95. Epub 2013 May 23.

NeuroCure Clinical Research Center and Experimental and Clinical Research Center, Charité University Medicine Berlin and Max Delbrück Center for Molecular Medicine, Berlin, Germany.

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http://dx.doi.org/10.1177/1352458513489757DOI Listing
December 2013

Functional and structural brain changes in anti-N-methyl-D-aspartate receptor encephalitis.

Ann Neurol 2013 Aug 8;74(2):284-96. Epub 2013 Jul 8.

Department of Neurology, Charité-Universitätsmedizin Berlin, Berlin, Germany; Berlin Center for Advanced Neuroimaging, Charité-Universitätsmedizin Berlin, Berlin, Germany.

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http://dx.doi.org/10.1002/ana.23932DOI Listing
August 2013