Publications by authors named "Alexander Tarakhovsky"

76Publications

The transgenic mouse: a new model to delineate platelet and leukocyte functions.

Blood 2019 01 14;133(4):331-343. Epub 2018 Nov 14.

Institute of Cardiovascular Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham, United Kingdom.

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January 2019

Drawing on disorder: How viruses use histone mimicry to their advantage.

J Exp Med 2018 07 22;215(7):1777-1787. Epub 2018 Jun 22.

Epigenetics DPU, Oncology and Immuno-inflammation TA Units, GlaxoSmithKline Medicines Research Centre, Stevenage, England, UK.

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July 2018

Viral Infection Identifies Micropeptides Differentially Regulated in smORF-Containing lncRNAs.

Genes (Basel) 2017 Aug 21;8(8). Epub 2017 Aug 21.

Laboratory of Virology and Infectious Diseases, The Rockefeller University, New York, NY 10065, USA.

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August 2017

Epigenetic drug discovery: breaking through the immune barrier.

Nat Rev Drug Discov 2016 12 21;15(12):835-853. Epub 2016 Oct 21.

Epinova Epigenetics Discovery Performance Unit, Immuno-Inflammation Therapy Area, GlaxoSmithKline, Medicines Research Centre, Stevenage SG1 2NY, UK.

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December 2016

Polycomb repressive complex 2 (PRC2) silences genes responsible for neurodegeneration.

Nat Neurosci 2016 10 15;19(10):1321-30. Epub 2016 Aug 15.

Friedman Brain Institute, Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, New York, USA.

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October 2016

Autism-like syndrome is induced by pharmacological suppression of BET proteins in young mice.

J Exp Med 2015 Oct 21;212(11):1771-81. Epub 2015 Sep 21.

Department of Neuroscience and Department of Psychiatry, Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029 Department of Neuroscience and Department of Psychiatry, Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029

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October 2015

Brd4 bridges the transcriptional regulators, Aire and P-TEFb, to promote elongation of peripheral-tissue antigen transcripts in thymic stromal cells.

Proc Natl Acad Sci U S A 2015 Aug 27;112(32):E4448-57. Epub 2015 Jul 27.

Division of Immunology, Department of Microbiology and Immunobiology, Harvard Medical School, Boston, MA 02115; Evergrande Center for Immunologic Diseases, Harvard Medical School and Brigham and Women's Hospital, Boston, MA 02115

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August 2015

Coupling of T cell receptor specificity to natural killer T cell development by bivalent histone H3 methylation.

J Exp Med 2015 Mar 16;212(3):297-306. Epub 2015 Feb 16.

Laboratory of Immune Cell Epigenetics and Signaling, The Rockefeller University, New York, NY 10065

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March 2015

The roles of individual mammalian argonautes in RNA interference in vivo.

PLoS One 2014 3;9(7):e101749. Epub 2014 Jul 3.

Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America.

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May 2016

Epigenetic control of immunity.

Cold Spring Harb Perspect Biol 2014 Jun 2;6(6). Epub 2014 Jun 2.

Laboratory of Lymphocyte Signaling, The Rockefeller University, New York, New York 10021.

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June 2014

The "histone mimicry" by pathogens.

Cold Spring Harb Symp Quant Biol 2013 14;78:81-90. Epub 2014 Apr 14.

Laboratory of Immune Cell Epigenetics and Signaling, The Rockefeller University, New York, New York 10065

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March 2015

Chromatin contributions to the regulation of innate immunity.

Annu Rev Immunol 2014 6;32:489-511. Epub 2014 Feb 6.

Department of Microbiology, Immunology, and Molecular Genetics, University of California, Los Angeles, California 90095; email:

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November 2014

Chromatin targeting drugs in cancer and immunity.

Genes Dev 2013 Aug;27(16):1731-8

Epinova DPU, Immuno-Inflammation Therapy Area, Medicines Research Centre, GlaxoSmithKline, Stevenage SG1 2NY, United Kingdom.

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August 2013

Logic of the inflammation-associated transcriptional response.

Adv Immunol 2013 ;119:107-33

Rockefeller University, New York, New York, USA.

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October 2013