Alexander Swarbrick

Alexander Swarbrick

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Alexander Swarbrick

Alexander Swarbrick

Publications by authors named "Alexander Swarbrick"

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Epigenomics of mammary gland development.

Breast Cancer Res 2018 09 3;20(1):100. Epub 2018 Sep 3.

The Kinghorn Cancer Centre, Cancer Research Division, Garvan Institute of Medical Research, Darlinghurst, NSW, 2010, Australia.

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http://dx.doi.org/10.1186/s13058-018-1031-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6122685PMC
September 2018

GPR65 inhibits experimental autoimmune encephalomyelitis through CD4 T cell independent mechanisms that include effects on iNKT cells.

Immunol Cell Biol 2018 02 19;96(2):128-136. Epub 2017 Dec 19.

Immunology Division, Garvan Institute of Medical Research, Sydney, NSW, Australia.

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http://dx.doi.org/10.1111/imcb.1031DOI Listing
February 2018

Discovering cancer vulnerabilities using high-throughput micro-RNA screening.

Nucleic Acids Res 2017 Dec;45(22):12657-12670

The Kinghorn Cancer Centre & Cancer Research Division, Garvan Institute of Medical Research, Darlinghurst, NSW 2010, Australia.

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http://dx.doi.org/10.1093/nar/gkx1072DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5728403PMC
December 2017

The Atypical Kinase RIOK1 Promotes Tumor Growth and Invasive Behavior.

EBioMedicine 2017 Jun 12;20:79-97. Epub 2017 Apr 12.

Institute of Molecular Medicine and Cell Research (IMMZ), Faculty of Medicine, Albert-Ludwigs-University (ALU), Freiburg, Germany; Faculty of Biology, ALU, Freiburg, Germany; BIOSS Centre for Biological Signalling Studies, BIOSS, ALU, Germany; German Cancer Consortium (DKTK, Freiburg) and German Cancer Research Center (DKFZ), Heidelberg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.ebiom.2017.04.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5478185PMC
June 2017

Phase 2 study of circulating microRNA biomarkers in castration-resistant prostate cancer.

Br J Cancer 2017 Apr 9;116(8):1002-1011. Epub 2017 Mar 9.

Cancer Division, The Kinghorn Cancer Centre/Garvan Institute of Medical Research, Darlinghurst, New South Wales 2010, Australia.

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http://dx.doi.org/10.1038/bjc.2017.50DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5396108PMC
April 2017

ID4 controls luminal lineage commitment in normal mammary epithelium and inhibits BRCA1 function in basal-like breast cancer.

Endocr Relat Cancer 2016 09 13;23(9):R381-92. Epub 2016 Jul 13.

The Kinghorn Cancer Centre and Cancer Research DivisionGarvan Institute of Medical Research, Darlinghurst, New South Wales, Australia St Vincent's Clinical SchoolFaculty of Medicine, University of New South Wales, Sydney, New South Wales, Australia

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https://erc.bioscientifica.com/view/journals/erc/23/9/R381.x
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http://dx.doi.org/10.1530/ERC-16-0196DOI Listing
September 2016

ID4 controls mammary stem cells and marks breast cancers with a stem cell-like phenotype.

Nat Commun 2015 Mar 27;6:6548. Epub 2015 Mar 27.

1] The Kinghorn Cancer Centre &Cancer Research Division, Garvan Institute of Medical Research, Darlinghurst, New South Wales 2010, Australia [2] St Vincent's Clinical School, Faculty of Medicine, UNSW, Kensington, New South Wales 2033, Australia.

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http://dx.doi.org/10.1038/ncomms7548DOI Listing
March 2015

ID proteins regulate diverse aspects of cancer progression and provide novel therapeutic opportunities.

Mol Ther 2014 Aug 14;22(8):1407-1415. Epub 2014 May 14.

Cancer Research Division & Kinghorn Cancer Centre, Garvan Institute of Medical Research, Darlinghurst, New South Wales, Australia; St Vincent's Clinical School, Faculty of Medicine, University of New South Wales, New South Wales, Australia. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S15250016163073
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http://dx.doi.org/10.1038/mt.2014.83DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4435600PMC
August 2014

Effects of a novel long noncoding RNA, lncUSMycN, on N-Myc expression and neuroblastoma progression.

J Natl Cancer Inst 2014 Jul 6;106(7). Epub 2014 Jun 6.

Affiliations of authors: Children's Cancer Institute Australia for Medical Research, Randwick NSW, Australia (PYL, GMM, AET, MW, BL, BBC, MK, TL); Department of Pharmacy and Biotechnology, University of Bologna, Bologna, Italy (DE, GM, GP); Kids Cancer Centre, Sydney Children's Hospital, Randwick NSW, Australia (GMM); Department of Pathology and Inflammation and Infection Research Centre, University of New South Wales, Kensington 2052, Australia (PP); Institute of Molecular Medicine, Martin Luther University, ZAMED, Halle, Germany (JLB, SH); School of Medicine and Public Health, Priority Research Centre for Cancer Research, University of Newcastle, Callaghan NSW, Australia (XDZ); Harry Perkins Institute of Medical Research, Centre for Medical Research, University of Western Australia, Nedlands WA, Australia (AF); Kinghorn Cancer Centre and Cancer Research Division, Garvan Institute of Medical Research, Darlinghurst NSW, Australia (AS); St Vincent's Clinical School, University of New South Wales, Darlinghurst NSW, Australia (AS, JSM, MED); Australian Centre for Nanomedicine, Randwick NSW, Australia (MK); Garvan Institute of Medical Research, Darlinghurst NSW, Australia (AS, JSM, MED); School of Women's & Children's Health, University of New South Wales, Randwick NSW, Australia (TL).

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https://academic.oup.com/jnci/article-lookup/doi/10.1093/jnc
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http://dx.doi.org/10.1093/jnci/dju113DOI Listing
July 2014

New insights into the role of ID proteins in breast cancer metastasis: a MET affair.

Breast Cancer Res 2014 May 15;16(2):305. Epub 2014 May 15.

Cancer Research Division, The Kinghorn Cancer Centre and Cancer Research Program Garvan Institute of Medical Research, 370 Victoria St, Darlinghurst, NSW, 2010, Australia .

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http://dx.doi.org/10.1186/bcr3654DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4053215PMC
May 2014

Could the properties of IL-27 make it an ideal adjuvant for anticancer immunotherapy?

Oncoimmunology 2013 Aug 1;2(8):e25409. Epub 2013 Jul 1.

Cancer Division; Garvan Institute of Medical Research; Sydney, NSW Australia ; St. Vincent's Clinical School; University of New South Wales; Sydney, NSW Australia.

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http://dx.doi.org/10.4161/onci.25409DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3782520PMC
August 2013

Therapeutic targets in triple negative breast cancer.

J Clin Pathol 2013 Jun 22;66(6):530-42. Epub 2013 Feb 22.

Department of Tissue Pathology and Diagnostic Oncology, Royal Prince Alfred Hospital, Camperdown, New South Wales, Australia.

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http://dx.doi.org/10.1136/jclinpath-2012-201361DOI Listing
June 2013

Involvement of Lyn and the atypical kinase SgK269/PEAK1 in a basal breast cancer signaling pathway.

Cancer Res 2013 Mar 1;73(6):1969-80. Epub 2013 Feb 1.

Cancer Research Program, The Kinghorn Cancer Centre, Garvan Institute of Medical Research, Sydney, New South Wales, Australia.

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http://dx.doi.org/10.1158/0008-5472.CAN-12-1472DOI Listing
March 2013

Tyrosine phosphorylation profiling reveals the signaling network characteristics of Basal breast cancer cells.

Cancer Res 2010 Nov 21;70(22):9391-401. Epub 2010 Sep 21.

Cancer Research Program, Garvan Institute of Medical Research, St. Vincent's Hospital Clinical School and Bioanalytical Mass Spectrometry Facility, University of New South Wales, Sydney, New South Wales, Australia.

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http://cancerres.aacrjournals.org/cgi/doi/10.1158/0008-5472.
Publisher Site
http://dx.doi.org/10.1158/0008-5472.CAN-10-0911DOI Listing
November 2010

The Hedgehog signalling pathway as a therapeutic target in early breast cancer development.

Expert Opin Ther Targets 2009 Sep;13(9):1095-103

Garvan Institute of Medical Research, Cancer Research Program, Darlinghurst 2010, NSW, Australia.

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http://dx.doi.org/10.1517/14728220903130612DOI Listing
September 2009

Cell cycle machinery: links with genesis and treatment of breast cancer.

Adv Exp Med Biol 2008 ;630:189-205

Cancer Research Program, Garvan Institute of Medical Research, Darlinghurst, NSW 2010, Australia.

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http://dx.doi.org/10.1007/978-0-387-78818-0_12DOI Listing
August 2008

Id1 cooperates with oncogenic Ras to induce metastatic mammary carcinoma by subversion of the cellular senescence response.

Proc Natl Acad Sci U S A 2008 Apr 31;105(14):5402-7. Epub 2008 Mar 31.

Cancer Research Program, Garvan Institute of Medical Research, Darlinghurst NSW 2010, Australia.

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http://dx.doi.org/10.1073/pnas.0801505105DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2291136PMC
April 2008

The helix-loop-helix protein Id1 requires cyclin D1 to promote the proliferation of mammary epithelial cell acini.

Cancer Res 2008 Apr;68(8):3026-36

Cancer Research Program, Garvan Institute of Medical Research, Faculty of Medicine, University of New South Wales, Sydney, New South Wales, Australia.

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http://cancerres.aacrjournals.org/content/68/8/3026.full.pdf
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http://cancerres.aacrjournals.org/cgi/doi/10.1158/0008-5472.
Publisher Site
http://dx.doi.org/10.1158/0008-5472.CAN-07-3079DOI Listing
April 2008

Hormonal regulation of the Grb14 signal modulator and its role in cell cycle progression of MCF-7 human breast cancer cells.

J Cell Physiol 2005 Apr;203(1):85-93

Cancer Research Program, Garvan Institute of Medical Research, St Vincent's Hospital, Sydney, New South Wales, Australia.

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http://dx.doi.org/10.1002/jcp.20199DOI Listing
April 2005

Regulation of cyclin expression and cell cycle progression in breast epithelial cells by the helix-loop-helix protein Id1.

Oncogene 2005 Jan;24(3):381-9

Cancer Research Program, Garvan Institute of Medical Research, St Vincent's Hospital, 384 Victoria St, Darlinghurst, Sydney, NSW 2010, Australia.

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http://dx.doi.org/10.1038/sj.onc.1208188DOI Listing
January 2005

p27(Kip1) induces quiescence and growth factor insensitivity in tamoxifen-treated breast cancer cells.

Cancer Res 2003 Aug;63(15):4322-6

Cancer Research Program, Garvan Institute of Medical Research, 384 Victoria Street, Darlinghurst, New South Wales 2010, Australia.

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August 2003

Mechanisms of growth arrest by c-myc antisense oligonucleotides in MCF-7 breast cancer cells: implications for the antiproliferative effects of antiestrogens.

Cancer Res 2002 Jun;62(11):3126-31

Cancer Research Program, Garvan Institute of Medical Research, St. Vincent's Hospital, 384 Victoria Street, Darlinghurst, Sydney, New South Wales 2010, Australia.

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June 2002