Publications by authors named "Alexander So"

100Publications

Current understanding of gout and optimal management strategies.

Authors:
Alexander So

Semin Arthritis Rheum 2020 06;50(3S):S1

Service of Rheumatology, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.semarthrit.2020.06.008DOI Listing
June 2020

Current understanding of gout and optimal management strategies.

Authors:
Alexander So

Semin Arthritis Rheum 2020 Jun 10;50(4):812. Epub 2020 Jun 10.

Service of Rheumatology, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.semarthrit.2020.06.002DOI Listing
June 2020

The protective role of the 3-mercaptopyruvate sulfurtransferase (3-MST)-hydrogen sulfide (HS) pathway against experimental osteoarthritis.

Arthritis Res Ther 2020 03 17;22(1):49. Epub 2020 Mar 17.

Service of Rheumatology, Department of Musculoskeletal Medicine, Centre Hospitalier Universitaire Vaudois and University of Lausanne, Lausanne, Switzerland.

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http://dx.doi.org/10.1186/s13075-020-02147-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7077027PMC
March 2020

Febuxostat, a Xanthine Oxidoreductase Inhibitor, Decreases NLRP3-dependent Inflammation in Macrophages by Activating the Purine Salvage Pathway and Restoring Cellular Bioenergetics.

Sci Rep 2019 11 21;9(1):17314. Epub 2019 Nov 21.

Service of Rheumatology, Department of Musculoskeletal Medicine, Centre Hospitalier Universitaire Vaudois, University of Lausanne, Lausanne, Switzerland.

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http://dx.doi.org/10.1038/s41598-019-53965-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6872548PMC
November 2019

IL1 inhibition in gout-where are we a decade on?

Authors:
Alexander So

Arthritis Res Ther 2019 11 11;21(1):233. Epub 2019 Nov 11.

Service de Rhumatologie, CHUV and University of Lausanne, Lausanne, Switzerland.

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http://dx.doi.org/10.1186/s13075-019-2027-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6849269PMC
November 2019

Gout, Hyperuricaemia and Crystal-Associated Disease Network (G-CAN) consensus statement regarding labels and definitions of disease states of gout.

Ann Rheum Dis 2019 11 9;78(11):1592-1600. Epub 2019 Sep 9.

Department of Medicine, Faculty of Medical and Health Sciences, University of Auckland, Auckland, New Zealand.

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http://dx.doi.org/10.1136/annrheumdis-2019-215933DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7288724PMC
November 2019

The target uric acid level in multimorbid patients with gout is difficult to achieve: data from a longitudinal Swiss single-centre cohort.

Swiss Med Wkly 2019 Aug 2;149:w20121. Epub 2019 Sep 2.

Department of Rheumatology, University Hospital Basel, Switzerland.

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http://dx.doi.org/10.4414/smw.2019.20121DOI Listing
August 2019

The role of the gasotransmitter hydrogen sulfide in pathological calcification.

Br J Pharmacol 2020 02 24;177(4):778-792. Epub 2019 Jul 24.

Service of Rheumatology, DAL, Lausanne University Hospital (CHUV), University of Lausanne, Lausanne, Switzerland.

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http://dx.doi.org/10.1111/bph.14772DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7024711PMC
February 2020

Reassessing the Safety Profile of Lesinurad in Combination with Xanthine Oxidase Inhibitor Therapy.

Rheumatol Ther 2019 Mar 14;6(1):101-108. Epub 2019 Feb 14.

Nephrology Division, University Hospital Limerick, Graduate Entry Medical School, Health Research Institute, University of Limerick, Limerick, Ireland.

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http://dx.doi.org/10.1007/s40744-019-0143-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6393267PMC
March 2019

Efficacy of anakinra in acute hydroxyapatite calcification-induced joint pain: A retrospective study of 23 cases.

Joint Bone Spine 2019 01 5;86(1):83-88. Epub 2018 Jun 5.

Service de rhumatologie, CHU de Bichat-Claude Bernard, AP-HP, 75018 Paris, France.

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http://dx.doi.org/10.1016/j.jbspin.2018.05.008DOI Listing
January 2019

The role of IL-1 in gout: from bench to bedside.

Rheumatology (Oxford) 2018 01;57(suppl_1):i12-i19

Service de Rhumatologie, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland.

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http://dx.doi.org/10.1093/rheumatology/kex449DOI Listing
January 2018

Inflammation in gout: mechanisms and therapeutic targets.

Nat Rev Rheumatol 2017 Nov 28;13(11):639-647. Epub 2017 Sep 28.

Department of Biochemistry, University of Lausanne, 155 Chemin des Boveresses, 1066 Epalinges, Switzerland.

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http://www.nature.com/doifinder/10.1038/nrrheum.2017.155
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http://dx.doi.org/10.1038/nrrheum.2017.155DOI Listing
November 2017

Complications iatrogènes : ce que tout médecin doit connaître.

Rev Med Suisse 2017 Mar;13(553):539-540

Service de rhumatologie, CHUV, Lausanne.

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March 2017

Revisiting the Role of Interleukin-1 Pathway in Osteoarthritis: Interleukin-1α and -1β, and NLRP3 Inflammasome Are Not Involved in the Pathological Features of the Murine Menisectomy Model of Osteoarthritis.

Front Pharmacol 2017 13;8:282. Epub 2017 Jun 13.

Département de l'appareil Locomoteur, Service of Rheumatology, Centre Hospitalier Universitaire Vaudois and University of LausanneLausanne, Switzerland.

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http://dx.doi.org/10.3389/fphar.2017.00282DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5468399PMC
June 2017

Imaging in Gout and Other Crystal-Related Arthropathies.

Rheum Dis Clin North Am 2016 11 9;42(4):621-644. Epub 2016 Sep 9.

Department of Rheumatology, Lausanne University Hospital, Av Pierre Decker 5, Lausanne 1011, Switzerland.

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https://linkinghub.elsevier.com/retrieve/pii/S0889857X163004
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http://dx.doi.org/10.1016/j.rdc.2016.07.005DOI Listing
November 2016

Why better treatment of gout is needed.

Authors:
Alexander K So

Clin Exp Rheumatol 2016 Jul-Aug;34(4 Suppl 98):63-5. Epub 2016 Jul 20.

Service de Rhumatologie, CHUV and University of Lausanne, Switzerland.

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December 2016

Guidelines for the treatment of gout: a Swiss perspective.

Swiss Med Wkly 2016 1;146:w14341. Epub 2016 Sep 1.

Service de Rhumatologie, CHUV, Lausanne, Switzerland.

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http://dx.doi.org/10.4414/smw.2016.14341DOI Listing
September 2017

Sodium Thiosulfate Prevents Chondrocyte Mineralization and Reduces the Severity of Murine Osteoarthritis.

PLoS One 2016 8;11(7):e0158196. Epub 2016 Jul 8.

Service of Rheumatology, Department of Musculoskeletal Medicine, Centre Hospitalier Universitaire Vaudois and University of Lausanne, Lausanne, Switzerland.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0158196PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4938519PMC
July 2017

Ultrasound can be useful to predict an evolution towards rheumatoid arthritis in patients with inflammatory polyarthralgia without anticitrullinated antibodies.

Joint Bone Spine 2017 May 28;84(3):299-303. Epub 2016 Jun 28.

Department of rheumatology, Lausanne university hospital, 4, avenue Pierre-Decker, 1011 Lausanne, Switzerland.

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https://linkinghub.elsevier.com/retrieve/pii/S1297319X163010
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http://dx.doi.org/10.1016/j.jbspin.2016.05.011DOI Listing
May 2017

[Spondylarthropathies: conventional treatments and anti-TNF].

Rev Med Suisse 2016 Mar;12(509):507-8, 510-1

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March 2016

[Spondylarthropathies in 2015].

Rev Med Suisse 2016 Mar;12(509):483

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March 2016

PASS Syndrome: An IL-1-Driven Autoinflammatory Disease.

Dermatology 2016 27;232(2):254-8. Epub 2016 Feb 27.

Department of Dermatology, University Hospital Center CHUV, Lausanne, Switzerland.

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http://dx.doi.org/10.1159/000443648DOI Listing
January 2017

Intracellular ATP Decrease Mediates NLRP3 Inflammasome Activation upon Nigericin and Crystal Stimulation.

J Immunol 2015 Dec 6;195(12):5718-24. Epub 2015 Nov 6.

Service de Rhumatologie, Département de l'Appareil Locomoteur, Centre Hospitalier Universitaire Vaudois, Université de Lausanne, 1011 Lausanne, Switzerland

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http://www.jimmunol.org/content/early/2015/11/06/jimmunol.14
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http://www.jimmunol.org/cgi/doi/10.4049/jimmunol.1402512
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http://dx.doi.org/10.4049/jimmunol.1402512DOI Listing
December 2015

Erratum to: A prospective evaluation of ultrasound as a diagnostic tool in acute microcrystalline arthritis.

Arthritis Res Ther 2015 Sep 16;17:255. Epub 2015 Sep 16.

Department of Rheumatology, Département de l'appareil locomoteur, Lausanne University Hospital (CHUV), Av Pierre Decker 5, Lausanne, 1011, Switzerland.

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http://arthritis-research.com/content/17/1/255
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http://dx.doi.org/10.1186/s13075-015-0746-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4573478PMC
September 2015

High level of anti-drug antibodies after intra-articular injection of anti-TNF.

Rheumatology (Oxford) 2015 Dec 28;54(12):2291-2. Epub 2015 Aug 28.

Service de rhumatologie, département de l'appareil locomoteur and.

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http://dx.doi.org/10.1093/rheumatology/kev325DOI Listing
December 2015

Interleukin-6 and chondrocyte mineralisation act in tandem to promote experimental osteoarthritis.

Ann Rheum Dis 2016 07 7;75(7):1372-9. Epub 2015 Aug 7.

Service of Rheumatology, Department of Musculoskeletal Medicine, CHUV and University of Lausanne, Lausanne, Switzerland.

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http://dx.doi.org/10.1136/annrheumdis-2015-207487DOI Listing
July 2016

A prospective evaluation of ultrasound as a diagnostic tool in acute microcrystalline arthritis.

Arthritis Res Ther 2015 Jul 22;17:188. Epub 2015 Jul 22.

Department of Rheumatology, Département de l'appareil locomoteur, Lausanne University Hospital (CHUV), Av Pierre Decker 5, 1011, Lausanne, Switzerland.

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http://link.springer.com/content/pdf/10.1186/s13075-015-0701
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http://arthritis-research.com/content/17/1/188
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http://dx.doi.org/10.1186/s13075-015-0701-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4511437PMC
July 2015

A 19-year-old woman with polyarthritis, anterior uveitis and coronary vasculitis: A case of adult Kawasaki disease.

Joint Bone Spine 2015 Dec 13;82(6):468-70. Epub 2015 Jul 13.

Rheumatology, CHUV, DAL, avenue Pierre Decker, Lausanne, Vaud, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.jbspin.2014.10.021DOI Listing
December 2015

Xanthine oxidoreductase regulates macrophage IL1β secretion upon NLRP3 inflammasome activation.

Nat Commun 2015 Mar 24;6:6555. Epub 2015 Mar 24.

Rheumatology Laboratory, Centre Hospitalier Universitaire Vaudois, Ave Pierre Decker 4, 1011 Lausanne, Switzerland.

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http://dx.doi.org/10.1038/ncomms7555DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4382995PMC
March 2015

Interleukin-1 as a therapeutic target in gout.

Curr Opin Rheumatol 2015 Mar;27(2):156-63

Department of Rheumatology, Lausanne University Hospital, CHUV, Lausanne, Switzerland.

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http://dx.doi.org/10.1097/BOR.0000000000000143DOI Listing
March 2015

Dual-energy computed tomography molecular imaging of pigmented villonodular synovitis.

Rheumatology (Oxford) 2015 Mar 11;54(3):457. Epub 2014 Dec 11.

Department of Diagnostic and Interventional Radiology, University Institute of Pathology, Lausanne University Hospital, Lausanne, Switzerland, General Electric Medical Systems Europe, Buc, France, Department of Rheumatology and Department of Orthopaedics and Traumatology, Lausanne University Hospital, Lausanne, Switzerland.

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https://academic.oup.com/rheumatology/article-lookup/doi/10.
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http://dx.doi.org/10.1093/rheumatology/keu473DOI Listing
March 2015

Improving cardiovascular and renal outcomes in gout: what should we target?

Nat Rev Rheumatol 2014 Nov 19;10(11):654-61. Epub 2014 Aug 19.

Hôpital Lariboisière, Fédération de Rhumatologie, Centre Viggo Petersen 2, rue Ambroise Parè 75475 Cedex 10, Paris, France.

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http://dx.doi.org/10.1038/nrrheum.2014.124DOI Listing
November 2014

Anti-tumor necrosis factor drug survival in axial spondyloarthritis is independent of the classification criteria.

Rheumatol Int 2015 Feb 29;35(2):295-302. Epub 2014 Jul 29.

Department of Rheumatology, Lausanne University Hospital, Avenue Pierre-Decker 4, 1011, Lausanne, Switzerland,

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http://link.springer.com/10.1007/s00296-014-3094-z
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http://dx.doi.org/10.1007/s00296-014-3094-zDOI Listing
February 2015

Dispensable role of myeloid differentiation primary response gene 88 (MyD88) and MyD88-dependent toll-like receptors (TLRs) in a murine model of osteoarthritis.

Joint Bone Spine 2014 Jul 2;81(4):320-4. Epub 2014 Apr 2.

DAL, Service of Rheumatology, Laboratory of Rheumatology, University of Lausanne, CHUV, Nestlé 05-5029, 1011 Lausanne, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.jbspin.2014.01.018DOI Listing
July 2014

The concept of the inflammasome and its rheumatologic implications.

Joint Bone Spine 2014 Oct 2;81(5):398-402. Epub 2014 Apr 2.

Service de rhumatologie, université de Lausanne, CHU Vaudois, avenue Pierre-Decker 4, 1011 Lausanne, Suisse.

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http://dx.doi.org/10.1016/j.jbspin.2014.02.009DOI Listing
October 2014

Emerging therapies for gout.

Rheum Dis Clin North Am 2014 May 20;40(2):375-87. Epub 2014 Feb 20.

Service de Rhumatologie, CHUV, Avenue Pierre Decker, Lausanne 1011, Switzerland.

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http://dx.doi.org/10.1016/j.rdc.2014.01.013DOI Listing
May 2014

Xanthine oxidase inhibition by febuxostat attenuates experimental atherosclerosis in mice.

Sci Rep 2014 Apr 1;4:4554. Epub 2014 Apr 1.

Pharmaceutical Department Research Laboratories, Teijin Institute for Bio-Medical Research, Teijin Pharma Limited, Hino, Tokyo, Japan.

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http://dx.doi.org/10.1038/srep04554DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3971401PMC
April 2014

Changing the awareness of low vitamin D status in a rheumatology population: a pre/post-study.

Swiss Med Wkly 2013 6;143:w13891. Epub 2013 Dec 6.

Center for Bone Diseases, Lausanne University Hospital, SWITZERLAND;

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http://dx.doi.org/10.4414/smw.2013.13891DOI Listing
June 2014

How to regulate neutrophils in gout.

Authors:
Alexander So

Arthritis Res Ther 2013 ;15(5):118

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http://dx.doi.org/10.1186/ar4316DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3978475PMC
September 2015

Targeting inflammasomes in rheumatic diseases.

Nat Rev Rheumatol 2013 Jul 14;9(7):391-9. Epub 2013 May 14.

Service of Rheumatology, Department of Musculoskeletal Medicine, Avenue Pierre Decker 4, Centre Hospitalier Universitaire Vaudois and University of Lausanne, 1011 Lausanne, Switzerland. alexanderkai-lik.so@ chuv.ch

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http://dx.doi.org/10.1038/nrrheum.2013.61DOI Listing
July 2013

Update on gout 2012.

Joint Bone Spine 2012 Dec 16;79(6):539-43. Epub 2012 Nov 16.

Service de Rhumatologie, Département de l'Appareil Locomoteur, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland.

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https://linkinghub.elsevier.com/retrieve/pii/S1297319X120021
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http://dx.doi.org/10.1016/j.jbspin.2012.09.005DOI Listing
December 2012

A pilot study of IL-1 inhibition in acute calcific periarthritis of the shoulder.

Ann Rheum Dis 2013 Mar 10;72(3):465-7. Epub 2012 Nov 10.

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http://dx.doi.org/10.1136/annrheumdis-2012-202380DOI Listing
March 2013

Two cases of Takayasu's arteritis occurring under anti-TNF therapy.

Joint Bone Spine 2013 Mar 19;80(2):211-3. Epub 2012 Sep 19.

Service de rhumatologie et centre des maladies osseuses, département de l'appareil locomoteur, hôpital orthopédique, 4, avenue Pierre-Decker, 1011 Lausanne, Switzerland.

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http://dx.doi.org/10.1016/j.jbspin.2012.07.015DOI Listing
March 2013

Canakinumab for acute gouty arthritis in patients with limited treatment options: results from two randomised, multicentre, active-controlled, double-blind trials and their initial extensions.

Ann Rheum Dis 2012 Nov 14;71(11):1839-48. Epub 2012 May 14.

Division of Rheumatology, Department of Medicine, University of Medicine and Dentistry of New Jersey/Robert Wood Johnson Medical School, New Brunswick, NJ 08901, USA;

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http://dx.doi.org/10.1136/annrheumdis-2011-200908DOI Listing
November 2012

Physical activity and energy expenditure in rheumatoid arthritis patients and matched controls.

Rheumatology (Oxford) 2012 Aug 25;51(8):1500-7. Epub 2012 Apr 25.

Service of Rheumatology, Musculoskeletal Department, Lausanne University Hospital, Av. Pierre-Decker 4, 1011 Lausanne, Switzerland.

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http://dx.doi.org/10.1093/rheumatology/kes067DOI Listing
August 2012

Microcrystals as DAMPs and their role in joint inflammation.

Rheumatology (Oxford) 2012 Jul 12;51(7):1154-60. Epub 2012 Feb 12.

Service de Rhumatologie, Centre Hospitalier Universitaire Vaudois, University of Lausanne, Avenue Pierre Decker, 1011 Lausanne, Switzerland.

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http://dx.doi.org/10.1093/rheumatology/ker524DOI Listing
July 2012

Systemic effects of epidural methylprednisolone injection on glucose tolerance in diabetic patients.

BMC Res Notes 2011 Dec 21;4:552. Epub 2011 Dec 21.

DAL (Département de l'appareil locomoteur), CHUV (Centre hospitalier universitaire vaudois), Lausanne, Switzerland.

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http://dx.doi.org/10.1186/1756-0500-4-552DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3298566PMC
December 2011

Osteoarthritis: Crystal-gazing into the pathogenesis of osteoarthritis.

Nat Rev Rheumatol 2011 Nov 1;7(12):688-9. Epub 2011 Nov 1.

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http://dx.doi.org/10.1038/nrrheum.2011.165DOI Listing
November 2011

Increased interleukin-10 production by ASC-deficient CD4+ T cells impairs bystander T-cell proliferation.

Immunology 2011 Sep 30;134(1):33-40. Epub 2011 Jun 30.

Service of Rheumatology, Department of l'Appareil Locomoteur, Centre Hospitalier Universitaire Vaudois, University of Lausanne, Lausanne, Switzerland.

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http://doi.wiley.com/10.1111/j.1365-2567.2011.03462.x
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http://dx.doi.org/10.1111/j.1365-2567.2011.03462.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3173692PMC
September 2011

PAR2 promotes vaccine-induced protection against Helicobacter infection in mice.

Gastroenterology 2011 Oct 23;141(4):1273-82, 1282.e1. Epub 2011 Jun 23.

Service of Gastroenterology and Hepatology, Department of Medicine, Centre Hospitalier Universitaire Vaudois and University of Lausanne, Lausanne, Switzerland.

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http://dx.doi.org/10.1053/j.gastro.2011.06.038DOI Listing
October 2011

High prevalence of hypovitaminosis D in a Swiss rheumatology outpatient population.

Swiss Med Wkly 2011 27;141:w13196. Epub 2011 May 27.

Center for Bone Diseases, Lausanne University Hospital-DAL, Avenue Pierre Decker 4, 1011 Lausanne, Switzerland.

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http://doi.emh.ch/smw.2011.13196
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http://dx.doi.org/10.4414/smw.2011.13196DOI Listing
November 2011

Clinical images: Polyostotic fibrous dysplasia.

Arthritis Rheum 2011 Sep;63(9):2616

Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland.

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http://dx.doi.org/10.1002/art.30456DOI Listing
September 2011

A controlled trial of the benefits of ultrasound-guided steroid injection for shoulder pain.

Joint Bone Spine 2012 Mar 25;79(2):166-9. Epub 2011 May 25.

Service de rhumatologie, DAL, CHUV, avenue Pierre-Decker 4, 1011 Lausanne, Switzerland.

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http://dx.doi.org/10.1016/j.jbspin.2011.04.001DOI Listing
March 2012

[Fibromyalgia diagnostic criteria].

Rev Med Suisse 2011 Mar;7(286):604, 606-8

Service de rhumatologie, Département de l'appareil locomoteur, CHUV, 1011 Lausanne.

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March 2011

[Ultrasound: an indispensable tool for the rheumatologist].

Rev Med Suisse 2011 Mar;7(286):571-2

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March 2011

Cervical myelopathy in hereditary multiple exostoses.

Joint Bone Spine 2011 Jul 15;78(4):412-4. Epub 2011 Apr 15.

Service de rhumatologie, département de l'appareil locomoteur, CHU Vaudois, Lausanne, Switzerland.

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http://dx.doi.org/10.1016/j.jbspin.2011.02.021DOI Listing
July 2011

Basic calcium phosphate crystals induce monocyte/macrophage IL-1β secretion through the NLRP3 inflammasome in vitro.

J Immunol 2011 Feb 14;186(4):2495-502. Epub 2011 Jan 14.

Department of Rheumatology, Centre Hospitalier Universitaire Vaudois, 1011 Lausanne, Switzerland.

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http://dx.doi.org/10.4049/jimmunol.1001284DOI Listing
February 2011

Functional multidisciplinary rehabilitation versus outpatient physiotherapy for non specific low back pain: randomized controlled trial.

Swiss Med Wkly 2010 22;140:w13133. Epub 2010 Dec 22.

Service de Rhumatologie, Département de l'Appareil Locomoteur (DAL), Centre Hospitalier Universitaire Vaudois, Av. Pierre-Decker 4, 1011 Lausanne, Suisse.

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http://doi.emh.ch/smw.2010.13133
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http://dx.doi.org/10.4414/smw.2010.13133DOI Listing
February 2011

The emerging role of interleukin-1β in autoinflammatory diseases.

Arthritis Rheum 2011 Feb;63(2):314-24

National Amyloidosis Centre, University College London Medical School, London, UK.

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http://doi.wiley.com/10.1002/art.30105
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http://dx.doi.org/10.1002/art.30105DOI Listing
February 2011

Hyperuricaemia and gout: state of the art and future perspectives.

Ann Rheum Dis 2010 Oct;69(10):1738-43

Bone and Joint Research Group, Department of Medicine, University of Auckland, Auckland, New Zealand.

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http://ard.bmj.com/cgi/doi/10.1136/ard.2010.136218
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http://dx.doi.org/10.1136/ard.2010.136218DOI Listing
October 2010

Epidemiology: Gout--bad for the heart as well as the joint.

Authors:
Alexander So

Nat Rev Rheumatol 2010 Jul;6(7):386-7

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http://dx.doi.org/10.1038/nrrheum.2010.78DOI Listing
July 2010

Uric acid transport and disease.

J Clin Invest 2010 Jun 1;120(6):1791-9. Epub 2010 Jun 1.

Service de Rhumatologie, Department of Musculoskeletal Medicine, University of Lausanne, Lausanne, Switzerland.

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http://www.jci.org/articles/view/42344
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http://dx.doi.org/10.1172/JCI42344DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2877959PMC
June 2010

Regulation of inflammasome activity.

Immunology 2010 Jul 10;130(3):329-36. Epub 2010 May 10.

Department of Biochemistry, University of Lausanne, Epalinges, Switzerland.

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http://doi.wiley.com/10.1111/j.1365-2567.2010.03283.x
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http://dx.doi.org/10.1111/j.1365-2567.2010.03283.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2913212PMC
July 2010

Mechanisms of inflammation in gout.

Arthritis Res Ther 2010 26;12(2):206. Epub 2010 Apr 26.

Service de Rheumatologie, Centre Hospitalier Universitaire Vaudois, Université de Lausanne, Avenue Pierre Decker, 1011 Lausanne, Suisse.

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http://dx.doi.org/10.1186/ar2952DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2888190PMC
September 2010

[Rheumatology in the aged].

Rev Med Suisse 2010 Mar;6(240):539

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March 2010

Protease-activated receptor 2 signalling promotes dendritic cell antigen transport and T-cell activation in vivo.

Immunology 2010 Jan 22;129(1):20-7. Epub 2009 Jun 22.

Service of Rheumatology, Department of Medicine, Centre Hospitalier Universitaire Vaudois, University of Lausanne, Lausanne, Switzerland.

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http://doi.wiley.com/10.1111/j.1365-2567.2009.03144.x
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http://dx.doi.org/10.1111/j.1365-2567.2009.03144.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2807483PMC
January 2010

Expression and function of the NALP3 inflammasome in rheumatoid synovium.

Immunology 2010 Feb 17;129(2):178-85. Epub 2009 Aug 17.

Laboratoire de Rhumatologie, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland.

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http://dx.doi.org/10.1111/j.1365-2567.2009.03174.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2814460PMC
February 2010

A magic bullet for gout?

Ann Rheum Dis 2009 Oct;68(10):1517-9

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http://dx.doi.org/10.1136/ard.2009.112508DOI Listing
October 2009

Inflammatory role of ASC in antigen-induced arthritis is independent of caspase-1, NALP-3, and IPAF.

J Immunol 2009 Sep 28;183(6):4003-12. Epub 2009 Aug 28.

Service of Rheumatology, Département de l'Appareil Locomoteur, Centre Hospitalier Universitaire Vaudois and University of Lausanne, University of Lausanne, Lausanne, Switzerland.

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http://www.jimmunol.org/content/early/2009/08/28/jimmunol.08
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http://www.jimmunol.org/cgi/doi/10.4049/jimmunol.0802173
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September 2009

Prevention of major depression in complex medically ill patients: preliminary results from a randomized, controlled trial.

Psychosomatics 2009 May-Jun;50(3):227-33

Dept. of Psychiatry; University of Groningen, P.O. Box 30.001; 9700 RB Groningen, The Netherlands.

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http://dx.doi.org/10.1176/appi.psy.50.3.227DOI Listing
October 2009

Thrombin-sensitive photodynamic agents: a novel strategy for selective synovectomy in rheumatoid arthritis.

J Control Release 2009 Sep 13;138(3):225-34. Epub 2009 May 13.

Laboratory of Pharmaceutics and Biopharmaceutics, Section of Pharmaceutical Sciences, University of Lausanne, University of Geneva, 30 Quai Ernest-Ansermet, CH-1211, Geneva, Switzerland.

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http://dx.doi.org/10.1016/j.jconrel.2009.05.012DOI Listing
September 2009

Inflammatory sciatica due to spinal tophaceous gout.

BMJ Case Rep 2009 5;2009. Epub 2009 Mar 5.

Centre Hospitalier Universitaire Vaudois, Medicine, Rue de Bugnon, Lausanne, 1011, Switzerland.

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http://dx.doi.org/10.1136/bcr.07.2008.0492DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3027899PMC
November 2011

Developments in the scientific and clinical understanding of gout.

Authors:
Alexander So

Arthritis Res Ther 2008 10;10(5):221. Epub 2008 Oct 10.

Service de Rhumatologie, Departement de Médecine, CHU Vaudois, University of Lausanne, Ave Pierre Decker, 1011 Lausanne, Switzerland.

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http://dx.doi.org/10.1186/ar2509DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2592794PMC
February 2009