Alexander Pertsemlidis

Alexander Pertsemlidis

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Alexander Pertsemlidis

Alexander Pertsemlidis

Publications by authors named "Alexander Pertsemlidis"

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48Publications

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The miR-195 Axis Regulates Chemoresistance through TUBB and Lung Cancer Progression through BIRC5.

Mol Ther Oncolytics 2019 Sep 6;14:288-298. Epub 2019 Aug 6.

Greehey Children's Cancer Research Institute, The University of Texas Health Science Center at San Antonio, San Antonio, TX 78229 USA.

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http://dx.doi.org/10.1016/j.omto.2019.07.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6727248PMC
September 2019

microRNA-2110 functions as an onco-suppressor in neuroblastoma by directly targeting Tsukushi.

PLoS One 2018 14;13(12):e0208777. Epub 2018 Dec 14.

Department of Chemistry and Biochemistry, Texas State University, San Marcos, Texas, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0208777PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6294380PMC
May 2019

CRISPR-Based Editing Reveals Edge-Specific Effects in Biological Networks.

CRISPR J 2018 08;1:286-293

1 Department of Bioengineering, The University of Texas at Dallas, Richardson, Texas.

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http://dx.doi.org/10.1089/crispr.2018.0018DOI Listing
August 2018

miR-195 potentiates the efficacy of microtubule-targeting agents in non-small cell lung cancer.

Cancer Lett 2018 07 13;427:85-93. Epub 2018 Apr 13.

Greehey Children's Cancer Research Institute, The University of Texas Health Science Center at San Antonio, TX, 78229, USA; Department of Cell Systems and Anatomy, The University of Texas Health Science Center at San Antonio, TX, 78229, USA; Department of Pediatrics, The University of Texas Health Science Center at San Antonio, TX, 78229, USA. Electronic address:

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http://dx.doi.org/10.1016/j.canlet.2018.04.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5953831PMC
July 2018

LMO1 functions as an oncogene by regulating TTK expression and correlates with neuroendocrine differentiation of lung cancer.

Oncotarget 2018 Jul 3;9(51):29601-29618. Epub 2018 Jul 3.

Greehey Children's Cancer Research Institute, UT Health Science Center at San Antonio, San Antonio, Texas, USA.

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http://dx.doi.org/10.18632/oncotarget.25642DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6049873PMC
July 2018

miR-195 targets cyclin D3 and survivin to modulate the tumorigenesis of non-small cell lung cancer.

Cell Death Dis 2018 02 7;9(2):193. Epub 2018 Feb 7.

Greehey Children's Cancer Research Institute, The University of Texas Health Science Center at San Antonio, San Antonio, TX, USA.

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http://dx.doi.org/10.1038/s41419-017-0219-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833354PMC
February 2018

Genome-wide association analysis of radiation resistance in Drosophila melanogaster.

PLoS One 2014 14;9(8):e104858. Epub 2014 Aug 14.

Department of Cell Biology, UT Southwestern Medical Center, Dallas, Texas, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0104858PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4133248PMC
March 2016

microRNA-449a functions as a tumor suppressor in neuroblastoma through inducing cell differentiation and cell cycle arrest.

RNA Biol 2015 ;12(5):538-54

a Greehey Children's Cancer Research Institute; The University of Texas Health Science Center at San Antonio ; San Antonio , TX USA.

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http://dx.doi.org/10.1080/15476286.2015.1023495DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4615578PMC
February 2016

Jonquailine, a new pretazettine-type alkaloid isolated from Narcissus jonquilla quail, with activity against drug-resistant cancer.

Fitoterapia 2015 Apr 16;102:41-8. Epub 2015 Jan 16.

Dipartimento di Scienze Chimiche, Universita' di Napoli Federico II, Complesso Universitario Monte Sant'Angelo, Via Cintia 4, 80126 Napoli, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.fitote.2015.01.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4942186PMC
April 2015

Genetic mutation of p53 and suppression of the miR-17∼92 cluster are synthetic lethal in non-small cell lung cancer due to upregulation of vitamin D Signaling.

Cancer Res 2015 Feb 17;75(4):666-75. Epub 2014 Dec 17.

Greehey Children's Cancer Research Institute, The University of Texas Health Science Center at San Antonio, San Antonio, Texas. Department of Cellular and Structural Biology, The University of Texas Health Science Center at San Antonio, San Antonio, Texas. Department of Pediatrics, The University of Texas Health Science Center at San Antonio, San Antonio, Texas.

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http://cancerres.aacrjournals.org/content/75/4/666.full.pdf
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http://cancerres.aacrjournals.org/content/early/2014/12/17/0
Web Search
http://cancerres.aacrjournals.org/cgi/doi/10.1158/0008-5472.
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http://dx.doi.org/10.1158/0008-5472.CAN-14-1329DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4333022PMC
February 2015

A high-throughput screen identifies miRNA inhibitors regulating lung cancer cell survival and response to paclitaxel.

RNA Biol 2013 Nov 30;10(11):1700-13. Epub 2013 Sep 30.

Greehey Children's Cancer Research Institute; Department of Cellular and Structural Biology; UT Health Science Center at San Antonio; San Antonio, TX USA; Greehey Children's Cancer Research Institute; Department of Pediatrics; UT Health Science Center at San Antonio; San Antonio, TX USA.

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http://www.tandfonline.com/doi/abs/10.4161/rna.26541
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http://dx.doi.org/10.4161/rna.26541DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3907480PMC
November 2013

microRNA regulation of cell viability and drug sensitivity in lung cancer.

Expert Opin Biol Ther 2012 Sep 26;12(9):1221-39. Epub 2012 Jun 26.

Greehey Children's Cancer Research Institute, Department of Cellular and Structural Biology, UT Health Science Center at San Antonio, San Antonio, TX 78229, USA.

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http://dx.doi.org/10.1517/14712598.2012.697149DOI Listing
September 2012

ZEB1 drives prometastatic actin cytoskeletal remodeling by downregulating miR-34a expression.

J Clin Invest 2012 Sep 1;122(9):3170-83. Epub 2012 Aug 1.

Department of Thoracic/Head and Neck Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.

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http://dx.doi.org/10.1172/JCI63608DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3428095PMC
September 2012

Cancer and neurodegenerative disorders: pathogenic convergence through microRNA regulation.

J Mol Cell Biol 2011 Jun 28;3(3):176-80. Epub 2011 Jan 28.

Harold C. Simmons Comprehensive Cancer Center, UT Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, Texas 75390, USA.

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http://dx.doi.org/10.1093/jmcb/mjq058DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3104012PMC
June 2011

Power of genetic association studies with fixed and random genotype frequencies.

Ann Hum Genet 2010 Sep 21;74(5):429-38. Epub 2010 Jul 21.

Donald W. Reynolds Cardiovascular Clinical Research Center, Eugene McDermott Center for Human Growth and Development, University of Texas Southwestern Medical Center, Dallas, TX 75390-8591, USA.

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http://dx.doi.org/10.1111/j.1469-1809.2010.00598.xDOI Listing
September 2010

microRNAs and lung cancer: tumors and 22-mers.

Cancer Metastasis Rev 2010 Mar;29(1):109-22

Harold C. Simmons Comprehensive Cancer Center, The University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX, 75390-8807, USA.

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http://dx.doi.org/10.1007/s10555-010-9204-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2884965PMC
March 2010

microRNAs mature with help from cancer biology.

Genome Biol 2009 20;10(7):310. Epub 2009 Jul 20.

Department of Biochemistry, UT Southwestern Medical Center, Dallas, TX 75930-8591, USA.

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http://dx.doi.org/10.1186/gb-2009-10-7-310DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2728524PMC
January 2010

Contextual extracellular cues promote tumor cell EMT and metastasis by regulating miR-200 family expression.

Genes Dev 2009 Sep;23(18):2140-51

Department of Thoracic/Head and Neck Medical Oncology, The University of Texas M.D. Anderson Cancer Center, Houston, Texas 77030, USA.

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http://dx.doi.org/10.1101/gad.1820209DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2751985PMC
September 2009

miR-93, miR-98, and miR-197 regulate expression of tumor suppressor gene FUS1.

Mol Cancer Res 2009 Aug 11;7(8):1234-43. Epub 2009 Aug 11.

Eugene McDermott Center for Human Growth and Development, University of Texas Southwestern Medical Center, Dallas, TX 75390-8591, USA.

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http://dx.doi.org/10.1158/1541-7786.MCR-08-0507DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2741087PMC
August 2009

Predicting potential miRNA target sites within gene promoters.

Bioorg Med Chem Lett 2009 Jul 18;19(14):3791-4. Epub 2009 Apr 18.

Departments of Pharmacology and Biochemistry, UT Southwestern Medical Center at Dallas, Dallas, TX 75390, USA.

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http://dx.doi.org/10.1016/j.bmcl.2009.04.032DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2709707PMC
July 2009

Genetic variation in PNPLA3 confers susceptibility to nonalcoholic fatty liver disease.

Nat Genet 2008 Dec 25;40(12):1461-5. Epub 2008 Sep 25.

Donald W Reynolds Cardiovascular Clinical Research Center, Eugene McDermott Center for Human Growth and Development, Dallas, TX 75390, USA.

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http://dx.doi.org/10.1038/ng.257DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2597056PMC
December 2008

Bayesian statistical studies of the Ramachandran distribution.

Stat Appl Genet Mol Biol 2005 22;4:Article35. Epub 2005 Nov 22.

UT Southwestern Medical Center.

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http://dx.doi.org/10.2202/1544-6115.1165DOI Listing
May 2006

A spectrum of PCSK9 alleles contributes to plasma levels of low-density lipoprotein cholesterol.

Am J Hum Genet 2006 Mar 20;78(3):410-22. Epub 2006 Jan 20.

McDermott Center for Human Growth and Development, University of Texas Southwestern Medical Center, Dallas, 75390-9046, USA.

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http://dx.doi.org/10.1086/500615DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1380285PMC
March 2006

Multiple rare variants in NPC1L1 associated with reduced sterol absorption and plasma low-density lipoprotein levels.

Proc Natl Acad Sci U S A 2006 Feb 31;103(6):1810-5. Epub 2006 Jan 31.

Donald W. Reynolds Cardiovascular Clinical Research Center, Department of Molecular Genetics, University of Texas Southwestern Medical Center, Dallas, TX 75390-9052, USA.

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http://dx.doi.org/10.1073/pnas.0508483103DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1413637PMC
February 2006

Analysis of the regulation of lin-41 during chick and mouse limb development.

Dev Dyn 2005 Dec;234(4):948-60

Department of Anatomy, University of Wisconsin, Madison, 53706, USA.

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http://dx.doi.org/10.1002/dvdy.20591DOI Listing
December 2005

Text comparison based on dynamic programming.

IEEE Eng Med Biol Mag 2004 Nov-Dec;23(6):66-71

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http://dx.doi.org/10.1109/memb.2004.1378640DOI Listing
May 2005

Low LDL cholesterol in individuals of African descent resulting from frequent nonsense mutations in PCSK9.

Nat Genet 2005 Feb 16;37(2):161-5. Epub 2005 Jan 16.

Donald W. Reynolds Cardiovascular Clinical Research Center, University of Texas Southwestern Medical Center, 5323 Harry Hines, Dallas, Texas 75390-9046, USA.

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http://www.nature.com/articles/ng1509
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http://dx.doi.org/10.1038/ng1509DOI Listing
February 2005

ELXR: a resource for rapid exon-directed sequence analysis.

Genome Biol 2004 28;5(5):R36. Epub 2004 Apr 28.

Eugene McDermott Center for Human Growth and Development, University of Texas Southwestern Medical Center, Harry Hines Boulevard, Dallas, TX 75390, USA.

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http://genomebiology.biomedcentral.com/articles/10.1186/gb-2
Publisher Site
http://dx.doi.org/10.1186/gb-2004-5-5-r36DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC416472PMC
October 2004

Multiple rare alleles contribute to low plasma levels of HDL cholesterol.

Science 2004 Aug;305(5685):869-72

Donald W. Reynolds Cardiovascular Clinical Research Center and McDermott Center for Human Growth and Development, University of Texas Southwestern Medical Center, Dallas, TX, 75390, USA.

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http://www.sciencemag.org/cgi/doi/10.1126/science.1099870
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http://dx.doi.org/10.1126/science.1099870DOI Listing
August 2004

SNPCEQer II: the integrated detection and analysis of SNPs in DNA sequences.

Appl Bioinformatics 2003 ;2(3):151-4

Eugene McDermott Center for Human Growth and Development, The University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.

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June 2004

Reading the fine print of the human genome.

IEEE Eng Med Biol Mag 2003 Mar-Apr;22(2):105-8

McDermott Center for Human Growth and Development, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd., Dallas, TX 75390-8591, USA.

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http://dx.doi.org/10.1109/memb.2003.1195706DOI Listing
August 2003

ARROGANT: an application to manipulate large gene collections.

Bioinformatics 2002 Nov;18(11):1410-7

Program in Biomedical Engineering, The University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, Texas 75390, USA.

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http://dx.doi.org/10.1093/bioinformatics/18.11.1410DOI Listing
November 2002