Alexander Penson

Alexander Penson

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Alexander Penson

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Publisher Correction: The long tail of oncogenic drivers in prostate cancer.

Authors:
Joshua Armenia Stephanie A M Wankowicz David Liu Jianjiong Gao Ritika Kundra Ed Reznik Walid K Chatila Debyani Chakravarty G Celine Han Ilsa Coleman Bruce Montgomery Colin Pritchard Colm Morrissey Christopher E Barbieri Himisha Beltran Andrea Sboner Zafeiris Zafeiriou Susana Miranda Craig M Bielski Alexander V Penson Charlotte Tolonen Franklin W Huang Dan Robinson Yi Mi Wu Robert Lonigro Levi A Garraway Francesca Demichelis Philip W Kantoff Mary-Ellen Taplin Wassim Abida Barry S Taylor Howard I Scher Peter S Nelson Johann S de Bono Mark A Rubin Charles L Sawyers Arul M Chinnaiyan Nikolaus Schultz Eliezer M Van Allen

Nat Genet 2019 Jul;51(7):1194

Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.

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http://dx.doi.org/10.1038/s41588-019-0451-6DOI Listing
July 2019

Altered Nuclear Export Signal Recognition as a Driver of Oncogenesis.

Authors:
Justin Taylor Maria Sendino Alexander N Gorelick Alessandro Pastore Matthew T Chang Alexander V Penson Elena I Gavrila Connor Stewart Ella M Melnik Florisela Herrejon Chavez Lillian Bitner Akihide Yoshimi Stanley Chun-Wei Lee Daichi Inoue Bo Liu Xiao J Zhang Anthony R Mato Ahmet Dogan Michael G Kharas Yuhong Chen Demin Wang Rajesh K Soni Ronald C Hendrickson Gorka Prieto Jose A Rodriguez Barry S Taylor Omar Abdel-Wahab

Cancer Discov 2019 Jul 8. Epub 2019 Jul 8.

Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, New York.

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http://dx.doi.org/10.1158/2159-8290.CD-19-0298DOI Listing
July 2019

Nbn-Mre11 interaction is required for tumor suppression and genomic integrity.

Authors:
Jun Hyun Kim Alexander V Penson Barry S Taylor John H J Petrini

Proc Natl Acad Sci U S A 2019 Jul 8;116(30):15178-15183. Epub 2019 Jul 8.

Molecular Biology Program, Memorial Sloan-Kettering Cancer Center, New York, NY 10065;

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http://dx.doi.org/10.1073/pnas.1905305116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6660787PMC
July 2019

Concurrent RB1 and TP53 Alterations Define a Subset of EGFR-Mutant Lung Cancers at risk for Histologic Transformation and Inferior Clinical Outcomes.

Authors:
Michael Offin Joseph M Chan Megan Tenet Hira A Rizvi Ronglai Shen Gregory J Riely Natasha Rekhtman Yahya Daneshbod Alvaro Quintanal-Villalonga Alexander Penson Matthew D Hellmann Maria E Arcila Marc Ladanyi Dana Pe'er Mark G Kris Charles M Rudin Helena A Yu

J Thorac Oncol 2019 Jun 19. Epub 2019 Jun 19.

Thoracic Oncology Service, Division of Solid Tumor Oncology, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York; Weill Cornell Medical College, New York, New York. Electronic address:

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http://dx.doi.org/10.1016/j.jtho.2019.06.002DOI Listing
June 2019

Microsatellite Instability Is Associated With the Presence of Lynch Syndrome Pan-Cancer.

Authors:
Alicia Latham Preethi Srinivasan Yelena Kemel Jinru Shia Chaitanya Bandlamudi Diana Mandelker Sumit Middha Jaclyn Hechtman Ahmet Zehir Marianne Dubard-Gault Christina Tran Carolyn Stewart Margaret Sheehan Alexander Penson Deborah DeLair Rona Yaeger Joseph Vijai Semanti Mukherjee Jesse Galle Mark A Dickson Yelena Janjigian Eileen M O'Reilly Neil Segal Leonard B Saltz Diane Reidy-Lagunes Anna M Varghese Dean Bajorin Maria I Carlo Karen Cadoo Michael F Walsh Martin Weiser Julio Garcia Aguilar David S Klimstra Luis A Diaz Jose Baselga Liying Zhang Marc Ladanyi David M Hyman David B Solit Mark E Robson Barry S Taylor Kenneth Offit Michael F Berger Zsofia K Stadler

J Clin Oncol 2019 Feb 30;37(4):286-295. Epub 2018 Oct 30.

1 Memorial Sloan Kettering Cancer Center, New York, NY.

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http://ascopubs.org/doi/10.1200/JCO.18.00283
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http://dx.doi.org/10.1200/JCO.18.00283DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6553803PMC
February 2019

Widespread Selection for Oncogenic Mutant Allele Imbalance in Cancer.

Authors:
Craig M Bielski Mark T A Donoghue Mayur Gadiya Aphrothiti J Hanrahan Helen H Won Matthew T Chang Philip Jonsson Alexander V Penson Alexander Gorelick Christopher Harris Alison M Schram Aijazuddin Syed Ahmet Zehir Paul B Chapman David M Hyman David B Solit Kevin Shannon Sarat Chandarlapaty Michael F Berger Barry S Taylor

Cancer Cell 2018 11 1;34(5):852-862.e4. Epub 2018 Nov 1.

Marie-Josée and Henry R. Kravis Center for Molecular Oncology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA; Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2018.10.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6234065PMC
November 2018

The Genomic Landscape of Endocrine-Resistant Advanced Breast Cancers.

Authors:
Pedram Razavi Matthew T Chang Guotai Xu Chaitanya Bandlamudi Dara S Ross Neil Vasan Yanyan Cai Craig M Bielski Mark T A Donoghue Philip Jonsson Alexander Penson Ronglai Shen Fresia Pareja Ritika Kundra Sumit Middha Michael L Cheng Ahmet Zehir Cyriac Kandoth Ruchi Patel Kety Huberman Lillian M Smyth Komal Jhaveri Shanu Modi Tiffany A Traina Chau Dang Wen Zhang Britta Weigelt Bob T Li Marc Ladanyi David M Hyman Nikolaus Schultz Mark E Robson Clifford Hudis Edi Brogi Agnes Viale Larry Norton Maura N Dickler Michael F Berger Christine A Iacobuzio-Donahue Sarat Chandarlapaty Maurizio Scaltriti Jorge S Reis-Filho David B Solit Barry S Taylor José Baselga

Cancer Cell 2018 09;34(3):427-438.e6

Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2018.08.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6327853PMC
September 2018

Genome doubling shapes the evolution and prognosis of advanced cancers.

Authors:
Craig M Bielski Ahmet Zehir Alexander V Penson Mark T A Donoghue Walid Chatila Joshua Armenia Matthew T Chang Alison M Schram Philip Jonsson Chaitanya Bandlamudi Pedram Razavi Gopa Iyer Mark E Robson Zsofia K Stadler Nikolaus Schultz Jose Baselga David B Solit David M Hyman Michael F Berger Barry S Taylor

Nat Genet 2018 08 16;50(8):1189-1195. Epub 2018 Jul 16.

Marie-Josée and Henry R. Kravis Center for Molecular Oncology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.

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http://dx.doi.org/10.1038/s41588-018-0165-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6072608PMC
August 2018

The long tail of oncogenic drivers in prostate cancer.

Authors:
Joshua Armenia Stephanie A M Wankowicz David Liu Jianjiong Gao Ritika Kundra Ed Reznik Walid K Chatila Debyani Chakravarty G Celine Han Ilsa Coleman Bruce Montgomery Colin Pritchard Colm Morrissey Christopher E Barbieri Himisha Beltran Andrea Sboner Zafeiris Zafeiriou Susana Miranda Craig M Bielski Alexander V Penson Charlotte Tolonen Franklin W Huang Dan Robinson Yi Mi Wu Robert Lonigro Levi A Garraway Francesca Demichelis Philip W Kantoff Mary-Ellen Taplin Wassim Abida Barry S Taylor Howard I Scher Peter S Nelson Johann S de Bono Mark A Rubin Charles L Sawyers Arul M Chinnaiyan Nikolaus Schultz Eliezer M Van Allen

Nat Genet 2018 05 2;50(5):645-651. Epub 2018 Apr 2.

Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.

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http://dx.doi.org/10.1038/s41588-018-0078-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6107367PMC
May 2018

Small-Cell Carcinomas of the Bladder and Lung Are Characterized by a Convergent but Distinct Pathogenesis.

Authors:
Matthew T Chang Alexander Penson Neil B Desai Nicholas D Socci Ronglai Shen Venkatraman E Seshan Ritika Kundra Adam Abeshouse Agnes Viale Eugene K Cha Xueli Hao Victor E Reuter Charles M Rudin Bernard H Bochner Jonathan E Rosenberg Dean F Bajorin Nikolaus Schultz Michael F Berger Gopa Iyer David B Solit Hikmat A Al-Ahmadie Barry S Taylor

Clin Cancer Res 2018 04 27;24(8):1965-1973. Epub 2017 Nov 27.

Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, New York.

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http://dx.doi.org/10.1158/1078-0432.CCR-17-2655DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5965261PMC
April 2018

Unifying cancer and normal RNA sequencing data from different sources.

Authors:
Qingguo Wang Joshua Armenia Chao Zhang Alexander V Penson Ed Reznik Liguo Zhang Thais Minet Angelica Ochoa Benjamin E Gross Christine A Iacobuzio-Donahue Doron Betel Barry S Taylor Jianjiong Gao Nikolaus Schultz

Sci Data 2018 04 17;5:180061. Epub 2018 Apr 17.

Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, New York 10065, USA.

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http://dx.doi.org/10.1038/sdata.2018.61DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5903355PMC
April 2018

Accelerating Discovery of Functional Mutant Alleles in Cancer.

Authors:
Matthew T Chang Tripti Shrestha Bhattarai Alison M Schram Craig M Bielski Mark T A Donoghue Philip Jonsson Debyani Chakravarty Sarah Phillips Cyriac Kandoth Alexander Penson Alexander Gorelick Tambudzai Shamu Swati Patel Christopher Harris JianJiong Gao Selcuk Onur Sumer Ritika Kundra Pedram Razavi Bob T Li Dalicia N Reales Nicholas D Socci Gowtham Jayakumaran Ahmet Zehir Ryma Benayed Maria E Arcila Sarat Chandarlapaty Marc Ladanyi Nikolaus Schultz José Baselga Michael F Berger Neal Rosen David B Solit David M Hyman Barry S Taylor

Cancer Discov 2018 02 15;8(2):174-183. Epub 2017 Dec 15.

Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, New York.

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http://dx.doi.org/10.1158/2159-8290.CD-17-0321DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5809279PMC
February 2018

Integrative Analysis Identifies Four Molecular and Clinical Subsets in Uveal Melanoma.

Authors:
A Gordon Robertson Juliann Shih Christina Yau Ewan A Gibb Junna Oba Karen L Mungall Julian M Hess Vladislav Uzunangelov Vonn Walter Ludmila Danilova Tara M Lichtenberg Melanie Kucherlapati Patrick K Kimes Ming Tang Alexander Penson Ozgun Babur Rehan Akbani Christopher A Bristow Katherine A Hoadley Lisa Iype Matthew T Chang Andrew D Cherniack Christopher Benz Gordon B Mills Roel G W Verhaak Klaus G Griewank Ina Felau Jean C Zenklusen Jeffrey E Gershenwald Lynn Schoenfield Alexander J Lazar Mohamed H Abdel-Rahman Sergio Roman-Roman Marc-Henri Stern Colleen M Cebulla Michelle D Williams Martine J Jager Sarah E Coupland Bita Esmaeli Cyriac Kandoth Scott E Woodman

Cancer Cell 2018 01;33(1):151

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http://dx.doi.org/10.1016/j.ccell.2017.12.013DOI Listing
January 2018

Erratum: Mutational landscape of metastatic cancer revealed from prospective clinical sequencing of 10,000 patients.

Authors:
Ahmet Zehir Ryma Benayed Ronak H Shah Aijazuddin Syed Sumit Middha Hyunjae R Kim Preethi Srinivasan Jianjiong Gao Debyani Chakravarty Sean M Devlin Matthew D Hellmann David A Barron Alison M Schram Meera Hameed Snjezana Dogan Dara S Ross Jaclyn F Hechtman Deborah F DeLair JinJuan Yao Diana L Mandelker Donavan T Cheng Raghu Chandramohan Abhinita S Mohanty Ryan N Ptashkin Gowtham Jayakumaran Meera Prasad Mustafa H Syed Anoop Balakrishnan Rema Zhen Y Liu Khedoudja Nafa Laetitia Borsu Justyna Sadowska Jacklyn Casanova Ruben Bacares Iwona J Kiecka Anna Razumova Julie B Son Lisa Stewart Tessara Baldi Kerry A Mullaney Hikmat Al-Ahmadie Efsevia Vakiani Adam A Abeshouse Alexander V Penson Philip Jonsson Niedzica Camacho Matthew T Chang Helen H Won Benjamin E Gross Ritika Kundra Zachary J Heins Hsiao-Wei Chen Sarah Phillips Hongxin Zhang Jiaojiao Wang Angelica Ochoa Jonathan Wills Michael Eubank Stacy B Thomas Stuart M Gardos Dalicia N Reales Jesse Galle Robert Durany Roy Cambria Wassim Abida Andrea Cercek Darren R Feldman Mrinal M Gounder A Ari Hakimi James J Harding Gopa Iyer Yelena Y Janjigian Emmet J Jordan Ciara M Kelly Maeve A Lowery Luc G T Morris Antonio M Omuro Nitya Raj Pedram Razavi Alexander N Shoushtari Neerav Shukla Tara E Soumerai Anna M Varghese Rona Yaeger Jonathan Coleman Bernard Bochner Gregory J Riely Leonard B Saltz Howard I Scher Paul J Sabbatini Mark E Robson David S Klimstra Barry S Taylor Jose Baselga Nikolaus Schultz David M Hyman Maria E Arcila David B Solit Marc Ladanyi Michael F Berger

Nat Med 2017 08;23(8):1004

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http://dx.doi.org/10.1038/nm0817-1004cDOI Listing
August 2017

Integrative Analysis Identifies Four Molecular and Clinical Subsets in Uveal Melanoma.

Authors:
A Gordon Robertson Juliann Shih Christina Yau Ewan A Gibb Junna Oba Karen L Mungall Julian M Hess Vladislav Uzunangelov Vonn Walter Ludmila Danilova Tara M Lichtenberg Melanie Kucherlapati Patrick K Kimes Ming Tang Alexander Penson Ozgun Babur Rehan Akbani Christopher A Bristow Katherine A Hoadley Lisa Iype Matthew T Chang Andrew D Cherniack Christopher Benz Gordon B Mills Roel G W Verhaak Klaus G Griewank Ina Felau Jean C Zenklusen Jeffrey E Gershenwald Lynn Schoenfield Alexander J Lazar Mohamed H Abdel-Rahman Sergio Roman-Roman Marc-Henri Stern Colleen M Cebulla Michelle D Williams Martine J Jager Sarah E Coupland Bita Esmaeli Cyriac Kandoth Scott E Woodman

Cancer Cell 2017 08;32(2):204-220.e15

Department of Melanoma Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA; Department of Systems Biology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2017.07.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5619925PMC
August 2017

Prospective Genomic Profiling of Prostate Cancer Across Disease States Reveals Germline and Somatic Alterations That May Affect Clinical Decision Making.

Authors:
Wassim Abida Joshua Armenia Anuradha Gopalan Ryan Brennan Michael Walsh David Barron Daniel Danila Dana Rathkopf Michael Morris Susan Slovin Brigit McLaughlin Kristen Curtis David M Hyman Jeremy C Durack Stephen B Solomon Maria E Arcila Ahmet Zehir Aijazuddin Syed Jianjiong Gao Debyani Chakravarty Hebert Alberto Vargas Mark E Robson Vijai Joseph Kenneth Offit Mark T A Donoghue Adam A Abeshouse Ritika Kundra Zachary J Heins Alexander V Penson Christopher Harris Barry S Taylor Marc Ladanyi Diana Mandelker Liying Zhang Victor E Reuter Philip W Kantoff David B Solit Michael F Berger Charles L Sawyers Nikolaus Schultz Howard I Scher

JCO Precis Oncol 2017 Jul 31;2017. Epub 2017 May 31.

Department of Medicine, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10065.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5558263PMC
http://dx.doi.org/10.1200/PO.17.00029DOI Listing
July 2017

Mutational landscape of metastatic cancer revealed from prospective clinical sequencing of 10,000 patients.

Authors:
Ahmet Zehir Ryma Benayed Ronak H Shah Aijazuddin Syed Sumit Middha Hyunjae R Kim Preethi Srinivasan Jianjiong Gao Debyani Chakravarty Sean M Devlin Matthew D Hellmann David A Barron Alison M Schram Meera Hameed Snjezana Dogan Dara S Ross Jaclyn F Hechtman Deborah F DeLair JinJuan Yao Diana L Mandelker Donavan T Cheng Raghu Chandramohan Abhinita S Mohanty Ryan N Ptashkin Gowtham Jayakumaran Meera Prasad Mustafa H Syed Anoop Balakrishnan Rema Zhen Y Liu Khedoudja Nafa Laetitia Borsu Justyna Sadowska Jacklyn Casanova Ruben Bacares Iwona J Kiecka Anna Razumova Julie B Son Lisa Stewart Tessara Baldi Kerry A Mullaney Hikmat Al-Ahmadie Efsevia Vakiani Adam A Abeshouse Alexander V Penson Philip Jonsson Niedzica Camacho Matthew T Chang Helen H Won Benjamin E Gross Ritika Kundra Zachary J Heins Hsiao-Wei Chen Sarah Phillips Hongxin Zhang Jiaojiao Wang Angelica Ochoa Jonathan Wills Michael Eubank Stacy B Thomas Stuart M Gardos Dalicia N Reales Jesse Galle Robert Durany Roy Cambria Wassim Abida Andrea Cercek Darren R Feldman Mrinal M Gounder A Ari Hakimi James J Harding Gopa Iyer Yelena Y Janjigian Emmet J Jordan Ciara M Kelly Maeve A Lowery Luc G T Morris Antonio M Omuro Nitya Raj Pedram Razavi Alexander N Shoushtari Neerav Shukla Tara E Soumerai Anna M Varghese Rona Yaeger Jonathan Coleman Bernard Bochner Gregory J Riely Leonard B Saltz Howard I Scher Paul J Sabbatini Mark E Robson David S Klimstra Barry S Taylor Jose Baselga Nikolaus Schultz David M Hyman Maria E Arcila David B Solit Marc Ladanyi Michael F Berger

Nat Med 2017 Jun 8;23(6):703-713. Epub 2017 May 8.

Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York, USA.

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http://www.nature.com/doifinder/10.1038/nm.4333
Publisher Site
http://dx.doi.org/10.1038/nm.4333DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5461196PMC
June 2017