Alexander Marson

Alexander Marson

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Alexander Marson

Alexander Marson

Publications by authors named "Alexander Marson"

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38Publications

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The HVEM-BTLA Axis Restrains T Cell Help to Germinal Center B Cells and Functions as a Cell-Extrinsic Suppressor in Lymphomagenesis.

Immunity 2019 Aug 13;51(2):310-323.e7. Epub 2019 Jun 13.

Department of Microbiology and Immunology, University of California, San Francisco, San Francisco, CA, USA; Howard Hughes Medical Institute, University of California, San Francisco, San Francisco, CA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.immuni.2019.05.022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6703922PMC
August 2019

miR-15/16 Restrain Memory T Cell Differentiation, Cell Cycle, and Survival.

Cell Rep 2019 Aug;28(8):2169-2181.e4

Department of Microbiology and Immunology, University of California, San Francisco, San Francisco, CA 94143, USA; Sandler Asthma Basic Research Center, University of California, San Francisco, San Francisco, CA 94143, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2019.07.064DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6715152PMC
August 2019

ARIH2 Is a Vif-Dependent Regulator of CUL5-Mediated APOBEC3G Degradation in HIV Infection.

Cell Host Microbe 2019 07 25;26(1):86-99.e7. Epub 2019 Jun 25.

Department of Cellular & Molecular Pharmacology, University of California, San Francisco, San Francisco, CA 94143, USA; Gladstone Institutes, San Francisco, CA 94158, USA; Quantitative Biosciences Institute (QBI), San Francisco, CA 94158, USA. Electronic address:

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http://dx.doi.org/10.1016/j.chom.2019.05.008DOI Listing
July 2019

Orthotopic replacement of T-cell receptor α- and β-chains with preservation of near-physiological T-cell function.

Nat Biomed Eng 2019 Jun 10. Epub 2019 Jun 10.

Institute for Medical Microbiology, Immunology and Hygiene, Technische Universität München, Munich, Germany.

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http://dx.doi.org/10.1038/s41551-019-0409-0DOI Listing
June 2019

CRISPR-Based Tools in Immunity.

Annu Rev Immunol 2019 Apr 30;37:571-597. Epub 2019 Jan 30.

Department of Microbiology and Immunology, University of California, San Francisco, California 94143, USA; email:

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http://dx.doi.org/10.1146/annurev-immunol-042718-041522DOI Listing
April 2019

A Mutation in the Transcription Factor Foxp3 Drives T Helper 2 Effector Function in Regulatory T Cells.

Immunity 2019 02 29;50(2):362-377.e6. Epub 2019 Jan 29.

Diabetes Center, University of California, San Francisco, San Francisco, CA 94143, USA; Sean N. Parker Autoimmune Research Laboratory, University of California, San Francisco, San Francisco, CA 94143, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S10747613183056
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http://dx.doi.org/10.1016/j.immuni.2018.12.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6476426PMC
February 2019

Genome-wide CRISPR Screens in Primary Human T Cells Reveal Key Regulators of Immune Function.

Cell 2018 12 15;175(7):1958-1971.e15. Epub 2018 Nov 15.

Department of Microbiology and Immunology, University of California, San Francisco, San Francisco, CA 94143, USA; Diabetes Center, University of California, San Francisco, San Francisco, CA 94143, USA; Innovative Genomics Institute, University of California, Berkeley, Berkeley, CA 94720, USA; UCSF Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA 94158, USA; Department of Medicine, University of California, San Francisco, San Francisco, CA 94143, USA; Chan Zuckerberg Biohub, San Francisco, CA 94158, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00928674183133
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http://dx.doi.org/10.1016/j.cell.2018.10.024DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6689405PMC
December 2018

Revisiting IL-2: Biology and therapeutic prospects.

Sci Immunol 2018 07;3(25)

Diabetes Center, University of California, San Francisco, San Francisco, CA, USA.

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http://immunology.sciencemag.org/lookup/doi/10.1126/sciimmun
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http://dx.doi.org/10.1126/sciimmunol.aat1482DOI Listing
July 2018

Genetic engineering in primary human B cells with CRISPR-Cas9 ribonucleoproteins.

J Immunol Methods 2018 06 31;457:33-40. Epub 2018 Mar 31.

Cardiovascular Research Institute, Sandler Asthma Basic Research Center, 555 Mission Bay Blvd S, University of California, San Francisco, San Francisco, CA 94143, USA; Department of Anatomy, 555 Mission Bay Blvd S, University of California, San Francisco, San Francisco, CA 94143, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jim.2018.03.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6124898PMC
June 2018

"T-bet"-ing on autoimmunity variants.

PLoS Genet 2017 09 7;13(9):e1006924. Epub 2017 Sep 7.

Department of Microbiology and Immunology, University of California, San Francisco, California, United States of America.

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http://dx.doi.org/10.1371/journal.pgen.1006924DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5589080PMC
September 2017

CRISPR/Cas9-mediated PD-1 disruption enhances anti-tumor efficacy of human chimeric antigen receptor T cells.

Sci Rep 2017 04 7;7(1):737. Epub 2017 Apr 7.

Helen Diller Family Comprehensive Cancer Center, University of California San Francisco, San Francisco, CA, 94158, USA.

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http://dx.doi.org/10.1038/s41598-017-00462-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5428439PMC
April 2017

A genome-wide CRISPR screen identifies a restricted set of HIV host dependency factors.

Nat Genet 2017 Feb 19;49(2):193-203. Epub 2016 Dec 19.

Ragon Institute of Massachusetts General Hospital (MGH), Massachusetts Institute of Technology (MIT), and Harvard University, Cambridge, Massachusetts, USA.

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http://dx.doi.org/10.1038/ng.3741DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5511375PMC
February 2017

A tissue checkpoint regulates type 2 immunity.

Nat Immunol 2016 Dec 17;17(12):1381-1387. Epub 2016 Oct 17.

Department of Medicine, University of California, San Francisco, San Francisco, California, USA.

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http://dx.doi.org/10.1038/ni.3582DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5275767PMC
December 2016

A Cas9 Ribonucleoprotein Platform for Functional Genetic Studies of HIV-Host Interactions in Primary Human T Cells.

Cell Rep 2016 10;17(5):1438-1452

Department of Microbiology and Immunology, University of California, San Francisco, San Francisco, CA 94143, USA; Diabetes Center, University of California, San Francisco, San Francisco, CA 94143, USA; Innovative Genomics Initiative, University of California, Berkeley, Berkeley, CA 94720, USA; Divisions of Infectious Diseases and Rheumatology, Department of Medicine, University of California, San Francisco, San Francisco, CA 94143, USA; UCSF Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA 94158, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2016.09.080DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5123761PMC
October 2016

Generation of knock-in primary human T cells using Cas9 ribonucleoproteins.

Proc Natl Acad Sci U S A 2015 Aug 27;112(33):10437-42. Epub 2015 Jul 27.

Diabetes Center, University of California, San Francisco, CA 94143; Division of Infectious Diseases, Department of Medicine, University of California, San Francisco, CA 94143; Innovative Genomics Initiative, University of California, Berkeley, CA 94720;

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http://dx.doi.org/10.1073/pnas.1512503112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4547290PMC
August 2015

Genetic basis of autoimmunity.

J Clin Invest 2015 Jun 1;125(6):2234-41. Epub 2015 Jun 1.

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http://dx.doi.org/10.1172/JCI78086DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4497748PMC
June 2015

Genetic and epigenetic fine mapping of causal autoimmune disease variants.

Nature 2015 Feb 29;518(7539):337-43. Epub 2014 Oct 29.

1] Broad Institute of MIT and Harvard, Cambridge, Massachusetts 02142, USA [2] Howard Hughes Medical Institute, Chevy Chase, Maryland 20815, USA [3] Department of Pathology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts 02114, USA [4] Center for Systems Biology and Center for Cancer Research, Massachusetts General Hospital, Boston, Massachusetts 02114, USA.

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http://dx.doi.org/10.1038/nature13835DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4336207PMC
February 2015

Successful medical management of a Nocardia farcinica multiloculated pontine abscess.

BMJ Case Rep 2013 Dec 5;2013. Epub 2013 Dec 5.

Department of Neurology, University of California, San Francisco, California, USA.

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http://dx.doi.org/10.1136/bcr-2013-201308DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3863074PMC
December 2013

Foxp3 occupancy and regulation of key target genes during T-cell stimulation.

Nature 2007 Feb 21;445(7130):931-5. Epub 2007 Jan 21.

Whitehead Institute for Biomedical Research, 9 Cambridge Center, Cambridge, Massachusetts 02142, USA.

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http://dx.doi.org/10.1038/nature05478DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3008159PMC
February 2007

PML bodies control the nuclear dynamics and function of the CHFR mitotic checkpoint protein.

Nat Struct Mol Biol 2004 Nov 3;11(11):1114-21. Epub 2004 Oct 3.

University of Cambridge, Cancer Research UK Department of Oncology and The Medical Research Council Cancer Cell Unit, Hills Road, Cambridge CB2 2XZ, UK.

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http://dx.doi.org/10.1038/nsmb837DOI Listing
November 2004