Publications





Melanoma staging: Evidence-based changes in the American Joint Committee on Cancer eighth edition cancer staging manual.
CA Cancer J Clin 2017 Nov 13;67(6):472-492. Epub 2017 Oct 13.
Professor of Melanoma and Surgical Oncology, Melanoma Institute Australia, The University of Sydney and Royal Prince Alfred Hospital, Sydney, New South Wales, Australia.

Co-targeting PI3K, mTOR, and IGF1R with small molecule inhibitors for treating undifferentiated pleomorphic sarcoma.
Cancer Biol Ther 2017 Oct 3;18(10):816-826. Epub 2017 Nov 3.
a Department of Surgical Oncology , The University of Texas MD Anderson Cancer Center , Houston , TX , USA.


High-Throughput Screening of Myxoid Liposarcoma Cell Lines: Survivin Is Essential for Tumor Growth.
Transl Oncol 2017 Aug 24;10(4):546-554. Epub 2017 Jun 24.
Department of Pathology, Leiden University Medical Center, Leiden, the Netherlands. Electronic address:



Trends in hepatocyte growth factor, insulin-like growth factor 1, thyroid-stimulating hormone, and leptin expression levels in uveal melanoma patient serum and tumor tissues: correlation to disease progression.
Melanoma Res 2017 Apr;27(2):126-133
Departments of aMelanoma Medical Oncology bOrbital Oncology and Ophthalmic Plastic Surgery cPlastic Surgery and Biostatistics dPathology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA eDepartment of Pathology, AC Camargo Cancer Center, São Paulo, Brazil.


IGF-1R and mTOR Blockade: Novel Resistance Mechanisms and Synergistic Drug Combinations for Ewing Sarcoma.
J Natl Cancer Inst 2016 Dec 30;108(12). Epub 2016 Aug 30.
Departments of Sarcoma Medical Oncology (SELC, BAM, VR, RSB, RR, JAL), Hematopathology (DV, HMA), Bioinformatics and Computational Biology (YW, JW), Investigational Cancer Therapeutics (AN, VS), Pediatrics-Patient Care (NCD), Experimental Therapeutics (IF, SS, WP), and Pathology (AJL), The University of Texas MD Anderson Cancer Center, Houston, TX; Departments of Radiology (EMR) and Molecular & Human Genetics (RLM), Baylor College of Medicine, Houston, TX; Department of Pediatric-Oncology, Texas Children's Hospital. Houston, TX (ASB); Departments of Chemical and Biomolecular Engineering and Bioengineering, Rice University, Houston, TX (AGM)

PAX7 Expression in Rhabdomyosarcoma, Related Soft Tissue Tumors, and Small Round Blue Cell Neoplasms.
Am J Surg Pathol 2016 Oct;40(10):1305-15
Departments of *Pathology ‡Pediatrics, Stanford University School of Medicine, Stanford, CA †Department of Medical Oncology, Institut Gustave-Roussy, Villejuif, France §Department of Internal Medicine, and Sylvester Comprehensive Cancer Center, Division of Hematology/Oncology, University of Miami Miller School of Medicine, Miami, FL ∥Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX.

American Joint Committee on Cancer acceptance criteria for inclusion of risk models for individualized prognosis in the practice of precision medicine.
CA Cancer J Clin 2016 Sep 19;66(5):370-4. Epub 2016 Jan 19.
Professor, Life Science, Arizona State University, Tempe, AZ; Professor, Laboratory Medicine and Pathology, Mayo Clinic School of Medicine, Rochester, MN; Chief Medical Officer, National Biomarker Development Alliance, Scottsdale, AZ.






SAR405838: A Novel and Potent Inhibitor of the MDM2:p53 Axis for the Treatment of Dedifferentiated Liposarcoma.
Clin Cancer Res 2016 Mar 16;22(5):1150-60. Epub 2015 Oct 16.
The Sarcoma Research Center, The University of Texas MD Anderson Cancer Center, Houston, Texas. Department of Surgical Oncology, Comprehensive Cancer Center, The Ohio State University (OSU), Columbus, Ohio. Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas.


Radiation-induced Sarcomas Occurring in Desmoid-type Fibromatosis Are Not Always Derived From the Primary Tumor.
Am J Surg Pathol 2015 Dec;39(12):1701-7
Departments of *Medical Oncology †Pathology ∥Radiation Oncology, Leiden University Medical Centre, Leiden, The Netherlands ‡Department of Pathology, Microbiology and Immunology, Vanderbilt University Medical Centre, Nashville, TN §Department of Pathology, Sarcoma Research Center, The University of Texas M.D. Anderson Cancer Center, Houston, TX ¶Robert J. Tomsich Pathology and Laboratory Medicine Institute, and Molecular Genetics, Cleveland Clinic, Taussig Cancer Centre and Lerner Research Institute, Cleveland, OH.

Dual Roles of RNF2 in Melanoma Progression.
Cancer Discov 2015 Dec 8;5(12):1314-27. Epub 2015 Oct 8.
Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas. Institute for Applied Cancer Science, The University of Texas MD Anderson Cancer Center, Houston, Texas. Institute for Health Transformation, The University of Texas System, Houston, Texas.





Template for Reporting Results of Biomarker Testing of Specimens From Patients With Gastrointestinal Stromal Tumors.
Arch Pathol Lab Med 2015 Oct 2;139(10):1271-5. Epub 2015 Mar 2.
From Surgical Pathology, Department of Pathology, Memorial Sloan-Kettering Cancer Center, New York, New York (Drs Hameed and Tang); the Department of Pathology, Oregon Health & Science University, Portland (Dr Corless); the Center for Sarcoma and Bone Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts (Dr George); the Department of Pathology, Brigham and Women's Hospital, Boston (Dr Hornick); the Department of Pathology, University of California, San Francisco, and the Veterans Affairs Medical Center, San Francisco (Dr Kakar); and the Department of Pathology, Sarcoma Research Center, University of Texas MD Anderson Cancer Center, Houston (Dr Lazar).


The Cancer Genomics Resource List 2014.
Arch Pathol Lab Med 2015 Aug 1;139(8):989-1008. Epub 2014 Dec 1.
From the Department of Pathology, Microbiology, and Immunology, Vanderbilt University School of Medicine, Nashville, Tennessee (Dr Zutter); the Department of Pathology, Clarient Diagnostic Services, Aliso Viejo, California (Dr Bloom); the Department of Pathology and Laboratory Medicine, Indiana University School of Medicine, Indianapolis (Dr Cheng); the Department of Pathology and Immunology, Washington University School of Medicine, St Louis, Missouri (Drs Hagemann and Pfeifer); Surveys, College of American Pathologists, Northfield, Illinois (Dr Kaufman); the Department of Pathology, Emory University, Atlanta, Georgia (Dr Krasinskas); the Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston (Dr Lazar); the Department of Pathology and Laboratory Medicine, Fletcher Allen Health Care, Burlington, Vermont (Dr Leonard); the Department of Pathology, Brigham and Women's Hospital, Boston, Massachusetts (Dr Lindeman); the Department of Pathology, Mayo Clinic, Rochester, Minnesota (Dr Moyer); Molecular and Genomic Pathology Laboratory, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania (Dr Nikiforova); the Department of Pathology, NorthShore University Health System, Evanston, Illinois (Dr Nowak); the Department of Pathology and Cell Biology, Columbia University Medical Center, New York, New York (Dr Sepulveda); the Department of Pathology, Case Medical Center/Case Western Reserve University, Cleveland, Ohio (Dr Willis); and the Department of Molecular Pathology and Hematopathology, University of Minnesota, Minneapolis (Dr Yohe).

The hepatocyte growth factor receptor as a potential therapeutic target for dedifferentiated liposarcoma.
Lab Invest 2015 Aug 1;95(8):951-61. Epub 2015 Jun 1.
1] Department of Surgical Oncology, University of Texas MD Anderson Cancer Center (MDACC), Houston, TX, USA [2] The Sarcoma Research Center, The University of Texas MD Anderson Cancer Center, Houston, TX, USA [3] Department of Surgical Oncology, Comprehensive Cancer Center, The Ohio State University (OSU), Columbus, OH, USA.


Metastatic atypical fibroxanthoma: a series of 11 cases including with minimal and no subcutaneous involvement.
Am J Dermatopathol 2015 Jun;37(6):455-61
*Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX; †Department of Pathology, Lahey Clinic, Burlington, MA; and ‡Dermatopathology Consultations.com, Needham Heights, MA.


Use of clinical next-generation sequencing to identify melanomas harboring SMARCB1 mutations.
J Cutan Pathol 2015 May 24;42(5):308-17. Epub 2015 Mar 24.
Department of Pathology and Laboratory Medicine, Section of Dermatopathology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.


BCOR-CCNB3 fusions are frequent in undifferentiated sarcomas of male children.
Mod Pathol 2015 Apr 31;28(4):575-86. Epub 2014 Oct 31.
1] Department of Pathology, Texas Children's Hospital, Houston, TX, USA [2] Department of Pathology & Immunology, Baylor College of Medicine, Houston, TX, USA [3] Department of Pediatrics, Baylor College of Medicine, Houston, TX, USA [4] Dan L. Duncan Cancer Center, Baylor College of Medicine, Houston, TX, USA.



Complete loss of PTEN protein expression correlates with shorter time to brain metastasis and survival in stage IIIB/C melanoma patients with BRAFV600 mutations.
Clin Cancer Res 2014 Nov 27;20(21):5527-36. Epub 2014 Aug 27.
Department of Melanoma Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, Texas. Department of Systems Biology, University of Texas MD Anderson Cancer Center, Houston, Texas.

Gankyrin is a predictive and oncogenic factor in well-differentiated and dedifferentiated liposarcoma.
Oncotarget 2014 Oct;5(19):9065-78
Transplantation Research Center, Samsung Biomedical Research Institute, Seoul, Republic of Korea. Department of Surgery, Samsung Medical Center, Samsung Biomedical Research Institute, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea. Sarcoma Research Center, Samsung Medical Center, Seoul, Republic of Korea.



Impact of surgical resection for subdiaphragmatic paragangliomas.
World J Surg 2014 Mar;38(3):733-41
Department of Surgical Oncology, Unit 1484, The University of Texas MD Anderson Cancer Center, P.O. Box 301402, Houston, TX, 77230-1402, USA,

Introducing new College of American Pathologists reporting templates for cancer biomarkers.
Arch Pathol Lab Med 2014 Feb 28;138(2):157-8. Epub 2013 Jun 28.
From the Department of Pathology, St Jude Medical Center, Fullerton, California (Dr Fitzgibbons); the Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston (Dr Lazar); and the College of American Pathologists, Northfield, Illinois (Dr Spencer).

CTNNB1 45F mutation is a molecular prognosticator of increased postoperative primary desmoid tumor recurrence: an independent, multicenter validation study.
Cancer 2013 Oct 31;119(20):3696-702. Epub 2013 Jul 31.
Sarcoma Service, Department of Surgery, Scientific Institute for Research, Hospitalization, and Health Care (IRCCS) Foundation, National Cancer Institute, Milan, Italy.

Primary cutaneous adenoid cystic carcinoma: a clinicopathologic and immunohistochemical study of 27 cases.
Am J Surg Pathol 2013 Oct;37(10):1603-11
*Department of Dermatopathology, St John's Institute of Dermatology, St Thomas' Hospital, London †Department of Pathology, Manchester Royal Infirmary, Manchester #Department of Pathology, Western General Hospital and The University of Edinburgh, Edinburgh, UK ‡Nelson R. Mandela School of Medicine and Central Hospital, Durban, South Africa §Sections of Dermatopathology and Soft Tissue/Sarcoma Pathology, MD Anderson Cancer Center, University of Texas, Houston, TX ∥Department of Pathology, Dublin Hospital, Dublin, Ireland ¶Charles University Medical Faculty Hospital, Pilsen, Czech Republic.

Heterogeneity and immunophenotypic plasticity of malignant cells in human liposarcomas.
Stem Cell Res 2013 Sep 12;11(2):772-81. Epub 2013 May 12.
Center for Stem Cell and Regenerative Medicine, The Brown Foundation Institute of Molecular Medicine, The University of Texas Health Science Center at Houston, Houston, TX 77030, USA.


Differential expression of cysteine dioxygenase 1 in complex karyotype liposarcomas.
Biomark Cancer 2014 6;6:1-10. Epub 2014 Apr 6.
Department of Laboratory Oncology Research, Curtis and Elizabeth Anderson Cancer Institute, Memorial University Medical Center, Savannah, GA, USA. ; Department of Biomedical Sciences, Mercer University School of Medicine-Savannah Campus, Savannah, GA, USA.










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