Alexander J Bishop, DPhil - Greehey Children's Cancer Research Institute - Associate Professor

Alexander J Bishop

DPhil

Greehey Children's Cancer Research Institute

Associate Professor

San Antonio, TX | United States

Alexander J Bishop, DPhil - Greehey Children's Cancer Research Institute - Associate Professor

Alexander J Bishop

DPhil
Introduction

Primary Affiliation: Greehey Children's Cancer Research Institute - San Antonio, TX , United States

Metrics

28

Publications

276

Profile Views

156

Reads

354

PubMed Central Citations

Publications

28Publications

156Reads

354PubMed Central Citations

Alkylating Agent-Induced NRF2 Blocks Endoplasmic Reticulum Stress-Mediated Apoptosis via Control of Glutathione Pools and Protein Thiol Homeostasis.

Mol Cancer Ther 2016 12 16;15(12):3000-3014. Epub 2016 Sep 16.

Greehey Children's Cancer Research Institute, University of Texas Health Science Center at San Antonio, San Antonio, Texas.

View Article
December 2016
16 Reads
7 PubMed Central Citations(source)
5.68 Impact Factor

Combined Gene Expression and RNAi Screening to Identify Alkylation Damage Survival Pathways from Fly to Human.

PLoS One 2016 21;11(4):e0153970. Epub 2016 Apr 21.

Greehey Children´s Cancer Research Institute, University of Texas Health Science Center at San Antonio, San Antonio, Texas, United States of America.

View Article
September 2016
5 Reads
3 PubMed Central Citations(source)
3.23 Impact Factor

Musashi1 Impacts Radio-Resistance in Glioblastoma by Controlling DNA-Protein Kinase Catalytic Subunit.

Am J Pathol 2016 09 25;186(9):2271-8. Epub 2016 Jul 25.

Greehey Children's Cancer Research Institute, University of Texas Health Science Center, San Antonio, Texas; Department of Cellular and Structural Biology, University of Texas Health Science Center, San Antonio, Texas. Electronic address:

View Article
September 2016
25 Reads
5 PubMed Central Citations(source)
4.59 Impact Factor

Inhibition of FoxM1-Mediated DNA Repair by Imipramine Blue Suppresses Breast Cancer Growth and Metastasis.

Clin Cancer Res 2016 Jul 29;22(14):3524-36. Epub 2016 Feb 29.

Department of Cell and Structure Biology, The University of Texas Health Science Center at San Antonio, San Antonio, Texas. Greehey Children's Cancer Research Institute, The University of Texas Health Science Center at San Antonio, San Antonio, Texas.

View Article
July 2016
8 Reads
6 PubMed Central Citations(source)
8.72 Impact Factor

ATR suppresses endogenous DNA damage and allows completion of homologous recombination repair.

PLoS One 2014 27;9(3):e91222. Epub 2014 Mar 27.

Department of Cellular and Structural Biology, University of Texas Health Science Center at San Antonio, San Antonio, Texas, United States of America; Greehey Children's Cancer Research Institute, University of Texas Health Science Center at San Antonio, San Antonio, Texas, United States of America; Cancer Therapy and Research Center, University of Texas Health Science Center, San Antonio, Texas, United States of America.

View Article
December 2015
5 Reads
5 PubMed Central Citations(source)
3.23 Impact Factor

Potential relationship between inadequate response to DNA damage and development of myelodysplastic syndrome.

Int J Mol Sci 2015 Jan 5;16(1):966-89. Epub 2015 Jan 5.

Greehey Children's Cancer Research Center, University of Texas Health Science Center San Antonio (UTHSCSA), 8403 Floyd Curl Drive, San Antonio, TX 78229, USA.

View Article
January 2015
3 Reads
2 PubMed Central Citations(source)
2.86 Impact Factor

Induction of homologous recombination following in utero exposure to DNA-damaging agents.

DNA Repair (Amst) 2013 Nov 10;12(11):912-21. Epub 2013 Sep 10.

Greehey Children's Cancer Research Institute, The University of Texas Health Science Center at San Antonio, 8403 Floyd Curl Drive, San Antonio, TX 78229, USA; Department of Cellular and Structural Biology, The University of Texas Health Science Center at San Antonio, 7703 Floyd Curl Drive, San Antonio, TX 78229, USA.

View Article
November 2013
5 Reads
1 PubMed Central Citation(source)

Myelodysplastic syndrome: an inability to appropriately respond to damaged DNA?

Exp Hematol 2013 Aug 30;41(8):665-74. Epub 2013 Apr 30.

Greehey Children's Cancer Research Center, University of Texas Health Science Center at San Antonio, TX 78229, USA.

View Article
August 2013
1 Read
13 PubMed Central Citations(source)
2.48 Impact Factor

Reducing confounding and suppression effects in TCGA data: an integrated analysis of chemotherapy response in ovarian cancer.

BMC Genomics 2012 26;13 Suppl 6:S13. Epub 2012 Oct 26.

Department of Electrical and Computer Engineering, Texas A&M University, College Station, TX, USA.

View Article
April 2013
4 Reads
13 PubMed Central Citations(source)
3.99 Impact Factor

Pathway Distiller - multisource biological pathway consolidation.

BMC Genomics 2012 26;13 Suppl 6:S18. Epub 2012 Oct 26.

Greehey Children's Cancer Research Institute, The University of Texas Health Science Center at San Antonio, San Antonio, TX, USA.

View Article
April 2013
4 Reads
4 PubMed Central Citations(source)
3.99 Impact Factor

RAD51 mutants cause replication defects and chromosomal instability.

Mol Cell Biol 2012 Sep 9;32(18):3663-80. Epub 2012 Jul 9.

Department of Molecular Medicine and Institute of Biotechnology, University of Texas Health Science Center, San Antonio, Texas, USA.

View Article
September 2012
6 Reads
16 PubMed Central Citations(source)
4.78 Impact Factor

Mice heterozygous for CREB binding protein are hypersensitive to γ-radiation and invariably develop myelodysplastic/myeloproliferative neoplasm.

Exp Hematol 2012 Apr 20;40(4):295-306.e5. Epub 2011 Dec 20.

Department of Cellular and Structural Biology, University of Texas Health Science Center at San Antonio, TX 78229, USA.

View Article
April 2012
9 Reads
10 PubMed Central Citations(source)
2.48 Impact Factor

Atg7 modulates p53 activity to regulate cell cycle and survival during metabolic stress.

Science 2012 Apr;336(6078):225-8

Center for Molecular Medicine, National Heart, Lung, and Blood Institute, Bethesda, MD 20892, USA.

View Article
April 2012
2 Reads
77 PubMed Central Citations(source)
31.48 Impact Factor

Mutant p53 disrupts role of ShcA protein in balancing Smad protein-dependent and -independent signaling activity of transforming growth factor-β (TGF-β).

J Biol Chem 2011 Dec 28;286(51):44023-34. Epub 2011 Oct 28.

Department of Cellular and Structural Biology, Greehey Children's Cancer Research Institute, University of Texas Health Science Center, San Antonio, TX 78229-3900, USA.

View Article
December 2011
5 Reads
5 PubMed Central Citations(source)
4.57 Impact Factor

A conditional mouse model for measuring the frequency of homologous recombination events in vivo in the absence of essential genes.

Mol Cell Biol 2011 Sep 27;31(17):3593-602. Epub 2011 Jun 27.

Department of Cellular and Structural Biology, University of Texas Health Science Center at San Antonio, San Antonio, TX 78229, USA.

View Article
September 2011
7 Reads
7 PubMed Central Citations(source)
4.78 Impact Factor

Dissection of a mouse eye for a whole mount of the retinal pigment epithelium.

J Vis Exp 2011 Feb 27(48). Epub 2011 Feb 27.

UT Health Science Center at San Antonio, Greehey Children's Cancer Research Institute, USA.

View Article
February 2011
4 Reads
13 PubMed Central Citations(source)

14-3-3 σ expression effects G2/M response to oxygen and correlates with ovarian cancer metastasis.

PLoS One 2011 Jan 10;6(1):e15864. Epub 2011 Jan 10.

Greehey Children's Cancer Research Institute, University of Texas Health Science Center, San Antonio, Texas, United States of America.

View Article
January 2011
5 Reads
7 PubMed Central Citations(source)
3.23 Impact Factor

PARP1 suppresses homologous recombination events in mice in vivo.

Nucleic Acids Res 2010 Nov 21;38(21):7538-45. Epub 2010 Jul 21.

Greehey Children's Cancer Research Institute, Department of Cellular and Structural Biology, The University of Texas Health Science Center at San Antonio, San Antonio, TX 78229, USA.

View Article
November 2010
4 Reads
12 PubMed Central Citations(source)
9.11 Impact Factor

Mouse WRN Helicase Domain Is Not Required for Spontaneous Homologous Recombination-Mediated DNA Deletion.

J Nucleic Acids 2010 Aug 19;2010. Epub 2010 Aug 19.

Greehey Children's Cancer Research Institute, The University of Texas Health Science Center at San Antonio, San Antonio, TX 78229, USA.

View Article
August 2010
4 Reads
3 PubMed Central Citations(source)

Building and analyzing protein interactome networks by cross-species comparisons.

BMC Syst Biol 2010 Mar 30;4:36. Epub 2010 Mar 30.

Greehey Children's Cancer Research Institute, The University of Texas Health Science Center at San Antonio, San Antonio, TX 78229, USA.

View Article
March 2010
4 Reads
29 PubMed Central Citations(source)
2.44 Impact Factor

A network of conserved damage survival pathways revealed by a genomic RNAi screen.

PLoS Genet 2009 Jun 19;5(6):e1000527. Epub 2009 Jun 19.

Greehey Children's Cancer Research Institute, University of Texas Health Science Center at San Antonio, San Antonio, TX, USA.

View Article
June 2009
4 Reads
27 PubMed Central Citations(source)

An analysis of normalization methods for Drosophila RNAi genomic screens and development of a robust validation scheme.

J Biomol Screen 2008 Sep 27;13(8):777-84. Epub 2008 Aug 27.

Greehey Children's Cancer Research Institute, The University of Texas Health Science Center at San Antonio, San Antonio, Texas 78229, USA.

View Article
September 2008
4 Reads
13 PubMed Central Citations(source)
2.42 Impact Factor

Involvement of homologous recombination in carcinogenesis.

Adv Genet 2007 ;58:67-87

Department of Pathology, Geffen School of Medicine, UCLA, Los Angeles, CA 90024, USA.

View Article
June 2007
3 Reads
21 PubMed Central Citations(source)
6.76 Impact Factor

In vivo DNA deletion assay to detect environmental and genetic predisposition to cancer.

Methods Mol Biol 2004 ;262:125-39

Department of Pathology, UCLA School of Medicine, Los Angeles, USA.

View Article
March 2004
5 Reads
8 PubMed Central Citations(source)

Ku86 deficiency leads to reduced intrachromosomal homologous recombination in vivo in mice.

DNA Repair (Amst) 2004 Feb;3(2):103-11

Department of Pathology, Environmental Health and Radiation Oncology, David Geffen School of Medicine and School of Public Health, UCLA, Los Angeles, CA 90024, USA.

View Article
February 2004
6 Reads
3 PubMed Central Citations(source)

Atm-, p53-, and Gadd45a-deficient mice show an increased frequency of homologous recombination at different stages during development.

Cancer Res 2003 Sep;63(17):5335-43

Department of Genetics, Harvard Medical School, Boston, Massachusetts 02115, USA.

View Article
September 2003
3 Reads
15 PubMed Central Citations(source)
9.33 Impact Factor

Role of homologous recombination in carcinogenesis.

Exp Mol Pathol 2003 Apr;74(2):94-105

Department of Genetics, Harvard Medical School, Boston, MA 02115, USA.

View Article
April 2003
3 Reads
16 PubMed Central Citations(source)
2.71 Impact Factor

Homologous Recombination and Its Role in Carcinogenesis.

J Biomed Biotechnol 2002 ;2(2):75-85

View Article
January 2002
2 Reads
13 PubMed Central Citations(source)
3.17 Impact Factor