Alexander H Peden

Alexander H Peden

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Alexander H Peden

Alexander H Peden

Publications by authors named "Alexander H Peden"

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19Publications

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Epitope mapping of the protease resistant products of RT-QuIC does not allow the discrimination of sCJD subtypes.

PLoS One 2019 17;14(6):e0218509. Epub 2019 Jun 17.

The National CJD Research & Surveillance Unit, Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, Scotland, United Kingdom.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0218509PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6576779PMC
June 2019

Amyloid-β accumulation in the CNS in human growth hormone recipients in the UK.

Acta Neuropathol 2017 08 27;134(2):221-240. Epub 2017 Mar 27.

National CJD Research & Surveillance Unit, Centre for Clinical Brain Sciences, Deanery of Clinical Medicine, University of Edinburgh, Edinburgh, EH4 2XU, UK.

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http://dx.doi.org/10.1007/s00401-017-1703-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5508038PMC
August 2017

UK Iatrogenic Creutzfeldt-Jakob disease: investigating human prion transmission across genotypic barriers using human tissue-based and molecular approaches.

Acta Neuropathol 2017 04 3;133(4):579-595. Epub 2016 Nov 3.

National CJD Research & Surveillance Unit, Centre for Clinical Brain Sciences, Deanery of Clinical Sciences, The University of Edinburgh, Edinburgh, UK.

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http://dx.doi.org/10.1007/s00401-016-1638-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5348565PMC
April 2017

The prion protein protease sensitivity, stability and seeding activity in variably protease sensitive prionopathy brain tissue suggests molecular overlaps with sporadic Creutzfeldt-Jakob disease.

Acta Neuropathol Commun 2014 Oct 21;2:152. Epub 2014 Oct 21.

National CJD Research & Surveillance Unit (NCJDRSU), School of Clinical Sciences (Division of Clinical Neurosciences), College of Medicine and Veterinary Medicine, University of Edinburgh, Western General Hospital, Crewe Road, Edinburgh EH4 2XU, UK.

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http://dx.doi.org/10.1186/s40478-014-0152-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4210614PMC
October 2014

Molecular pathology in neurodegenerative diseases.

Curr Drug Targets 2012 Nov;13(12):1548-59

National CJD Research & Surveillance Unit, University of Edinburgh, Western General Hospital, Edinburgh, UK.

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http://dx.doi.org/10.2174/138945012803530134DOI Listing
November 2012

The application of in vitro cell-free conversion systems to human prion diseases.

Acta Neuropathol 2011 Jan 10;121(1):135-43. Epub 2010 Jun 10.

Components and vCJD Research, National Science Laboratories, Scottish National Blood Transfusion Service, Edinburgh, EH 17 7QT, UK.

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http://dx.doi.org/10.1007/s00401-010-0708-8DOI Listing
January 2011

Distinct stability states of disease-associated human prion protein identified by conformation-dependent immunoassay.

J Virol 2010 Nov 15;84(22):12030-8. Epub 2010 Sep 15.

National CJD Surveillance Unit, Western General Hospital, Edinburgh, EH4 2XU, UK.

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http://dx.doi.org/10.1128/JVI.01057-10DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2977900PMC
November 2010

Effects of human PrPSc type and PRNP genotype in an in-vitro conversion assay.

Neuroreport 2008 Dec;19(18):1783-6

National CJD Surveillance Unit, School of Molecular and Clinical Medicine (Pathology), The Roslin Institute, Edinburgh, UK.

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http://dx.doi.org/10.1097/WNR.0b013e328318edfaDOI Listing
December 2008

Advances in the development of a screening test for variant Creutzfeldt-Jakob disease.

Expert Opin Med Diagn 2008 Feb;2(2):207-19

Postdoctoral Research Fellow University of Edinburgh, National CJD Surveillance Unit (NCJDSU), School of Molecular and Clinical Medicine (Pathology), Western General Hospital, Crewe Road, Edinburgh EH4 2XU, UK +44 0131 537 1980 ; +44 0131 343 1404 ;

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http://dx.doi.org/10.1517/17530059.2.2.207DOI Listing
February 2008

Abnormal prion protein in the pituitary in sporadic and variant Creutzfeldt-Jakob disease.

J Gen Virol 2007 Mar;88(Pt 3):1068-72

National Creutzfeldt-Jakob Disease Surveillance Unit (NCJDSU) and Division of Pathology, School of Molecular and Clinical Medicine, University of Edinburgh, Western General Hospital, Edinburgh, UK.

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http://dx.doi.org/10.1099/vir.0.81913-0DOI Listing
March 2007

Risks of transmission of variant Creutzfeldt-Jakob disease by blood transfusion.

Folia Neuropathol 2005 ;43(4):271-8

National Kreutzfeld-Jakob Disiease Surveillance Unit, Division of Pathology, School of Molecular and Clinical Medicine, University of Edinburgh, Western General Hospital, EH4 2XU, United Kingdom.

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April 2006

Detection and localization of PrPSc in the skeletal muscle of patients with variant, iatrogenic, and sporadic forms of Creutzfeldt-Jakob disease.

Am J Pathol 2006 Mar;168(3):927-35

National Creutzfeldt-Jakob Disease Surveillance Unit and Division of Pathology, School of Molecular and Clinical Medicine, University of Edinburgh, Western General Hospital, Edinburgh, United Kingdom.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1606529PMC
http://dx.doi.org/10.2353/ajpath.2006.050788DOI Listing
March 2006

Review: pathology of variant Creutzfeldt-Jakob disease.

Folia Neuropathol 2004 ;42 Suppl A:85-91

National CJD Surveillance Unit, Western General Hospital, Edinburgh EH4 2XU, United Kingdom.

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October 2004

Preclinical vCJD after blood transfusion in a PRNP codon 129 heterozygous patient.

Lancet 2004 Aug 7-13;364(9433):527-9

National Creutzfeldt-Jakob Disease Surveillance Unit, Division of Pathology, School of Molecular and Clinical Medicine, University of Edinburgh, Western General Hospital, Edinburgh EH4 2XU, UK.

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http://dx.doi.org/10.1016/S0140-6736(04)16811-6DOI Listing
August 2004

Attenuation of the activity of the cAMP-specific phosphodiesterase PDE4A5 by interaction with the immunophilin XAP2.

J Biol Chem 2003 Aug 16;278(35):33351-63. Epub 2003 Jun 16.

Veterans Affairs Medical Center, Huntsman Cancer Institute, Department of Medicine, Division of Oncology, University of Utah Health Sciences Center, Salt Lake City, Utah 84148, USA.

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http://www.jbc.org/lookup/doi/10.1074/jbc.M303269200
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http://dx.doi.org/10.1074/jbc.M303269200DOI Listing
August 2003