Alexander Guminski

Alexander Guminski

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Alexander Guminski

Alexander Guminski

Publications by authors named "Alexander Guminski"

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Decoding a mysterious morphology with molecular pathology: chondroid metaplasia in a metastatic gastrointestinal stromal tumour after imatinib therapy.

Pathology 2020 Apr 26;52(3):396-398. Epub 2020 Feb 26.

NSW Health Pathology, Department of Anatomical Pathology, Royal North Shore Hospital, St Leonards, NSW, Australia; Cancer Diagnosis and Pathology Research Group, Kolling Institute of Medical Research, Royal North Shore Hospital, St Leonards, NSW, Australia; Sydney University Medical School, University of Sydney, NSW, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.pathol.2019.12.007DOI Listing
April 2020

Chronic lymphocytic leukemia, skin and other second cancers.

Leuk Lymphoma 2019 Dec 24;60(13):3104-3106. Epub 2019 Sep 24.

Royal North Shore Hospital, Joint CLL Dermatology and Oncology Clinic, St Leonards, Sydney, Australia.

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http://dx.doi.org/10.1080/10428194.2019.1665669DOI Listing
December 2019

Immunotherapy and other systemic therapies for cutaneous SCC.

Oral Oncol 2019 12 9;99:104459. Epub 2019 Nov 9.

Department of Medical Oncology, Royal North Shore Hospital and Northern Clinical School, University of Sydney, Australia; Department of Medical Oncology, Royal Adelaide Hospital and Adelaide Cancer Centre, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.oraloncology.2019.104459DOI Listing
December 2019

Checkpoint Inhibitor-Associated Autoimmune Diabetes Is Distinct From Type 1 Diabetes.

J Clin Endocrinol Metab 2019 Nov;104(11):5499-5506

Melanoma Institute Australia and the University of Sydney, Sydney, New South Wales, Australia.

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http://dx.doi.org/10.1210/jc.2019-00423DOI Listing
November 2019

Characteristics and outcomes of oncology unit patients requiring admission to an Australian intensive care unit.

Intern Med J 2019 06;49(6):734-739

Department of Medical Oncology, Northern Sydney Cancer Centre, Royal North Shore Hospital, Sydney, New South Wales, Australia.

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http://doi.wiley.com/10.1111/imj.14160
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http://dx.doi.org/10.1111/imj.14160DOI Listing
June 2019

Management of Regional Lymph Nodes in Patients with Merkel Cell Carcinoma Following a Positive Sentinel Node Biopsy: Less May be More, But is Either Enough?

Ann Surg Oncol 2019 Feb 27;26(2):315-317. Epub 2018 Nov 27.

Faculty of Medicine and Health Sciences, The University of Sydney, Sydney, NSW, Australia.

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http://dx.doi.org/10.1245/s10434-018-7076-3DOI Listing
February 2019

Stereotactic Body Radiotherapy for Oligometastatic Prostate Cancer Detected via Prostate-specific Membrane Antigen Positron Emission Tomography.

Eur Urol Oncol 2018 12 23;1(6):531-537. Epub 2018 May 23.

Radiation Oncology Department, Northern Sydney Cancer Centre, Royal North Shore Hospital, St. Leonards, NSW, Australia; Northern Clinical School, University of Sydney, St. Leonards, NSW, Australia; Genesis Cancer Care, Sydney, Australia.

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http://dx.doi.org/10.1016/j.euo.2018.04.017DOI Listing
December 2018

Advanced Renal Cell Cancer and Low-Dose Palliative Radiation Treatment: A Case of a Substantial and Sustained Treatment Response.

Case Rep Oncol 2018 Sep-Dec;11(3):756-762. Epub 2018 Nov 27.

Northern Sydney Cancer Centre, Royal North Shore Hospital, Sydney, New South Wales, Australia.

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http://dx.doi.org/10.1159/000493913DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6323401PMC
November 2018

Survival and prognostic factors for patients with melanoma brain metastases in the era of modern systemic therapy.

Pigment Cell Melanoma Res 2018 07 10;31(4):509-515. Epub 2018 Jan 10.

Department of Medical Oncology, Royal North Shore Hospital, St Leonards, NSW, Australia.

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http://doi.wiley.com/10.1111/pcmr.12682
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http://dx.doi.org/10.1111/pcmr.12682DOI Listing
July 2018

PD-1 Blockade with Cemiplimab in Advanced Cutaneous Squamous-Cell Carcinoma.

N Engl J Med 2018 07 4;379(4):341-351. Epub 2018 Jun 4.

From the Departments of Dermatology and Head and Neck Surgery, University of Texas MD Anderson Cancer Center, Houston (M.R.M.), and South Texas Accelerated Research Therapeutics (START), San Antonio (K.P.P.) - both in Texas; the Department of Medical Oncology, Peter MacCallum Cancer Centre and University of Melbourne, Melbourne, VIC (D.R., A.A.T.), the Department of Medical Oncology, Royal North Shore Hospital, St. Leonards, VIC (A.G.), the Department of Medical Oncology, Sir Charles Gairdner Hospital, Perth, WA (A.M.L.), and Royal Brisbane and Women's Hospital and University of Queensland, Brisbane (B.G.M.H.) - all in Australia; the Department of Dermatology, Brigham and Women's Hospital (C.D.S.), the Department of Dermatology, Harvard Medical School (C.D.S.), and the Department of Medical Oncology, Dana-Farber Cancer Institute (G.R.) - all in Boston; Schleswig-Holstein University Hospital, Kiel (A.H.), and University Hospital Essen, Essen and German Cancer Consortium, Essen (D.S.) - both in Germany; University of Colorado Denver, School of Medicine, Aurora (K.D.L.); the Departments of Head and Neck-Endocrine Oncology (C.H.C.) and Cutaneous Oncology (N.I.K.), H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL; the Division of Medical Oncology, Department of Medicine, Washington University School of Medicine, St. Louis (L.H.-A.); the Department of Dermatology, Stanford University School of Medicine, Redwood City (A.L.S.C.), and the Division of Dermatology, City of Hope, Duarte (B.M.) - both in California; the Department of Medicine, Head and Neck Medical Oncology, Memorial Sloan Kettering Cancer Center, New York (L.A.D.), and Regeneron Pharmaceuticals, Tarrytown (F.S., M.M., K.M., G.D.Y., I.L., M.G.F.) - both in New York; Regeneron Pharmaceuticals, Basking Ridge, NJ (B.G., S.L., J.L., J.B., E.S.); University of Arizona Cancer Center, Tucson (H.M.B.), and Banner MD Anderson Cancer (J.H.) and the Department of Medical Oncology, Banner MD Anderson Cancer Center (J.N.), Gilbert - all in Arizona; Medical Oncology Department, Vall D'Hebron University Hospital (I.B.), and Institut Català D'Oncologia, Oncobell Program (IDIBELL), L'Hospitalet de Llobregat (M.G.-M.), Barcelona, and START Madrid-FJD, Hospital Fundación Jiménez Díaz, Madrid (V.M.) - all in Spain; Sarah Cannon Research Institute, Nashville (M.L.J.); and the Department of Hematology and Medical Oncology, Winship Cancer Institute, Emory University, Atlanta (T.K.O.).

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http://www.nejm.org/doi/10.1056/NEJMoa1805131
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http://dx.doi.org/10.1056/NEJMoa1805131DOI Listing
July 2018

Combination nivolumab and ipilimumab or nivolumab alone in melanoma brain metastases: a multicentre randomised phase 2 study.

Lancet Oncol 2018 05 27;19(5):672-681. Epub 2018 Mar 27.

Peter MacCallum Cancer Centre, University of Melbourne, Melbourne, VIC, Australia; Medical, Dental and Health Sciences, University of Melbourne, Parkville, VIC, Australia.

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http://dx.doi.org/10.1016/S1470-2045(18)30139-6DOI Listing
May 2018

The spectrum, incidence, kinetics and management of endocrinopathies with immune checkpoint inhibitors for metastatic melanoma.

Eur J Endocrinol 2018 Feb 29;178(2):173-180. Epub 2017 Nov 29.

Department of Endocrinology, Royal North Shore Hospital, Sydney, Australia.

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http://dx.doi.org/10.1530/EJE-17-0810DOI Listing
February 2018

A multireferral centre retrospective cohort analysis on the experience in treatment of metastatic uveal melanoma and utilization of sequential liver-directed treatment and immunotherapy.

Melanoma Res 2017 06;27(3):243-250

aDepartment of Medical Oncology, Royal North Shore Hospital bDepartment of Medical Oncology Melanoma Institute Australia cDepartment of Medical Oncology, The University of Sydney, Sydney, New South Wales, Australia dDepartment of Medical Oncology, Istituto Nazionale Tumori 'Fondazione Pascale', Naples, Campania, Italy.

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http://dx.doi.org/10.1097/CMR.0000000000000343DOI Listing
June 2017

Survival of patients with melanoma brain metastasis treated with stereotactic radiosurgery and active systemic drug therapies.

Eur J Cancer 2017 04 23;75:169-178. Epub 2017 Feb 23.

Melanoma Institute Australia, The University of Sydney, NSW, Australia; Genesis Cancer Care, Mater Radiation Oncology, North Sydney, Australia; Mater Hospital, North Sydney NSW, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.ejca.2017.01.007DOI Listing
April 2017

Pneumonitis in Patients Treated With Anti-Programmed Death-1/Programmed Death Ligand 1 Therapy.

J Clin Oncol 2017 Mar 30;35(7):709-717. Epub 2016 Sep 30.

Jarushka Naidoo, Kaitlin M. Woo, Tunc Iyriboz, Darragh Halpenny, Jane Cunningham, Jamie E. Chaft, Neil H. Segal, Margaret K. Callahan, Alexander M. Lesokhin, Jonathan Rosenberg, Martin H. Voss, Charles M. Rudin, Hira Rizvi, Xue Hou, Katherine Rodriguez, Melanie Albano, Ruth-Ann Gordon, Charles Leduc, Natasha Rekhtman, Bianca Harris, Jedd D. Wolchok, Michael A. Postow, and Matthew D. Hellmann, Memorial Sloan Kettering Cancer Center; Jamie E. Chaft, Neil H. Segal, Margaret K. Callahan, Alexander M. Lesokhin, Jonathan Rosenberg, Martin H. Voss, Charles M. Rudin, Jedd D. Wolchok, Michael A. Postow, and Matthew D. Hellmann, Weill Cornell Medical College, New York, NY; Jarushka Naidoo, Sidney Kimmel Cancer Center at Johns Hopkins University, Baltimore, MD; Xuan Wang, Peking University Cancer Hospital and Institute, Beijing; Xue Hou, Sun Yat-sen University Cancer Center, Guangdong Province, People's Republic of China; Xuan Wang, Matteo S. Carlino, Benjamin Y. Kong, and Georgina V. Long, The University of Sydney; Alexander M. Menzies and Alexander D. Guminski, Royal North Shore and Mater Hospital; and Matteo S. Carlino and Benjamin Y. Kong, Westmead and Blacktown Hospitals, Sydney, Australia.

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http://dx.doi.org/10.1200/JCO.2016.68.2005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5559901PMC
March 2017

Nonmelanoma Cutaneous Head and Neck Cancer and Merkel Cell Carcinoma: Current Concepts, Advances, and Controversies.

J Clin Oncol 2015 Oct 8;33(29):3338-45. Epub 2015 Sep 8.

Sandro V. Porceddu, Princess Alexandra Hospital and University of Queensland, Brisbane, Queensland; Michael J. Veness, Westmead Cancer Cancer Centre; Michael J. Veness and Alexander Guminski, University of Sydney; and Alexander Guminski, Royal North Shore Hospital, Sydney, New South Wales, Australia.

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http://dx.doi.org/10.1200/JCO.2014.60.7333DOI Listing
October 2015

The nature and management of metastatic melanoma after progression on BRAF inhibitors: effects of extended BRAF inhibition.

Cancer 2014 Oct 1;120(20):3142-53. Epub 2014 Jul 1.

Melanoma Institute Australia, Sydney, New South Wales, Australia; Department of Medical Oncology, Crown Princess Mary Cancer Center, Westmead Hospital, Sydney, New South Wales, Australia; University of Sydney, Sydney, New South Wales, Australia.

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http://dx.doi.org/10.1002/cncr.28851DOI Listing
October 2014

Intra-arterial infusion and chemo-embolization for melanoma liver metastases.

J Surg Oncol 2014 Mar 5;109(4):376-82. Epub 2014 Feb 5.

Department of Radiology, Royal North Shore Hospital, St Leonards, Australia.

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http://dx.doi.org/10.1002/jso.23551DOI Listing
March 2014

Focal overexpression of CEACAM6 contributes to enhanced tumourigenesis in head and neck cancer via suppression of apoptosis.

Mol Cancer 2012 Sep 28;11:74. Epub 2012 Sep 28.

University of Queensland Diamantina Institute, Epithelial Pathobiology Group, Princess Alexandra Hospital, Queensland, Australia.

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http://dx.doi.org/10.1186/1476-4598-11-74DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3515475PMC
September 2012

Role of intratumoural heterogeneity in cancer drug resistance: molecular and clinical perspectives.

EMBO Mol Med 2012 Aug 25;4(8):675-84. Epub 2012 Jun 25.

Epithelial Cancer Program, University of Queensland, Diamantine Institute, Princess Alexandra Hospital, Queensland, Australia.

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http://dx.doi.org/10.1002/emmm.201101131DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3494067PMC
August 2012

Tumor-initiating activity and tumor morphology of HNSCC is modulated by interactions between clonal variants within the tumor.

Lab Invest 2010 Nov 26;90(11):1594-603. Epub 2010 Jul 26.

Epithelial Pathobiology Group, Diamantina Institute, Princess Alexandra Hospital, University of Queensland, Woolloongabba, Queensland, Australia.

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http://dx.doi.org/10.1038/labinvest.2010.131DOI Listing
November 2010

Loss of osteoclasts contributes to development of osteosarcoma pulmonary metastases.

Cancer Res 2010 Sep 7;70(18):7063-72. Epub 2010 Sep 7.

The University of Queensland, Level 4, R Wing, Princess Alexandra Hospital, Ipswich Road, Woolloongabba, Queensland 4102, Australia.

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http://dx.doi.org/10.1158/0008-5472.CAN-09-4291DOI Listing
September 2010

Cisplatin treatment induces a transient increase in tumorigenic potential associated with high interleukin-6 expression in head and neck squamous cell carcinoma.

Mol Cancer Ther 2010 Aug 3;9(8):2430-9. Epub 2010 Aug 3.

Diamantina Institute, The University of Queensland, Princess Alexandra Hospital, Ipswich Road, Brisbane, Queensland, Australia.

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http://mct.aacrjournals.org/lookup/doi/10.1158/1535-7163.MCT
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http://dx.doi.org/10.1158/1535-7163.MCT-10-0258DOI Listing
August 2010

Predicting response to IL-2 therapy for metastatic melanoma.

Expert Rev Anticancer Ther 2009 Nov;9(11):1571-5

Melanoma Institute Australia, North Sydney, NSW, Australia.

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http://dx.doi.org/10.1586/era.09.131DOI Listing
November 2009

Valproic acid as a therapeutic agent for head and neck squamous cell carcinomas.

Cancer Chemother Pharmacol 2009 Feb 9;63(3):381-9. Epub 2008 Apr 9.

Epithelial Pathobiology Group, Cancer Biology Programme, Diamantina Institute for Cancer, Immunology and Metabolic Medicine, University of Queensland, Princess Alexandra Hospital, Woolloongabba, Brisbane, Australia.

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http://link.springer.com/content/pdf/10.1007/s00280-008-0747
Web Search
http://link.springer.com/10.1007/s00280-008-0747-1
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http://dx.doi.org/10.1007/s00280-008-0747-1DOI Listing
February 2009

Ankyrin repeat domain 1, ANKRD1, a novel determinant of cisplatin sensitivity expressed in ovarian cancer.

Clin Cancer Res 2008 Nov;14(21):6924-32

Westmead Institute for Cancer Research, University of Sydney at the Westmead Millennium Institute, Westmead Hospital, Westmead, NSW, Australia.

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http://dx.doi.org/10.1158/1078-0432.CCR-07-5189DOI Listing
November 2008

MRP2 (ABCC2) and cisplatin sensitivity in hepatocytes and human ovarian carcinoma.

Gynecol Oncol 2006 Feb 5;100(2):239-46. Epub 2005 Oct 5.

Department of Gynaecological Oncology, Westmead Hospital, University of Sydney at Westmead Millennium Institute, WESTMEAD, NSW 2145, Australia.

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http://dx.doi.org/10.1016/j.ygyno.2005.08.046DOI Listing
February 2006

Exploiting novel cell cycle targets in the development of anticancer agents.

Curr Cancer Drug Targets 2005 Mar;5(2):85-102

Cancer Biology Programme, Centre for Immunology and Cancer Research, University of Queensland, Princess Alexandra Hospital, Queensland, Australia.

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http://dx.doi.org/10.2174/1568009053202090DOI Listing
March 2005

Scientists and clinicians test their metal-back to the future with platinum compounds.

Lancet Oncol 2002 May;3(5):312-8

Department of Medical Oncology and Westmead Institute for Cancer Research, University of Sydney at the Westmead Millennium Institute, Westmead Hospital, NSW 2145, Australia.

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http://dx.doi.org/10.1016/s1470-2045(02)00733-7DOI Listing
May 2002