Publications by authors named "Alexander Egle"

87Publications

RNA editing contributes to epitranscriptome diversity in chronic lymphocytic leukemia.

Leukemia 2020 Jul 30. Epub 2020 Jul 30.

Department of Internal Medicine III with Haematology, Medical Oncology, Haemostaseology, Infectiology and Rheumatology, Oncologic Center, Salzburg Cancer Research Institute-Laboratory for Immunological and Molecular Cancer Research (SCRI-LIMCR), Paracelsus Medical University, Salzburg, Austria.

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http://dx.doi.org/10.1038/s41375-020-0995-6DOI Listing
July 2020

Anti-coagulation for COVID-19 treatment: both anti-thrombotic and anti-inflammatory?

J Thromb Thrombolysis 2020 Jul 6. Epub 2020 Jul 6.

Department of Internal Medicine II, Division of Cardiology, Paracelsus Medical University of Salzburg, Salzburg, Austria.

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http://dx.doi.org/10.1007/s11239-020-02212-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7338133PMC
July 2020

Low Expression of miR-20a-5p Predicts Benefit to Bevacizumab in Metastatic Breast Cancer Patients Treated within the TANIA Phase III Trial.

J Clin Med 2020 Jun 1;9(6). Epub 2020 Jun 1.

Laboratory for Immunological and Molecular Cancer Research (SCRI-LIMCR), Medical Oncology, Haemostaseology, Infectiology and Rheumatology, Department of Internal Medicine III with Haematology, Salzburg Cancer Research Institute, Oncologic Center Salzburg, Paracelsus Medical University Salzburg, 5020 Salzburg, Austria.

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http://dx.doi.org/10.3390/jcm9061663DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7355487PMC
June 2020

TCL1 transgenic mice as a model for CD49d-high chronic lymphocytic leukemia.

Leukemia 2020 09 21;34(9):2498-2502. Epub 2020 Feb 21.

Department of Internal Medicine III with Hematology, Medical Oncology, Hemostaseology, Infectiology and Rheumatology, Oncologic Center, Salzburg Cancer Research Institute-Laboratory for Immunological and Molecular Cancer Research (SCRI-LIMCR), Paracelsus Medical University, Salzburg, Austria.

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http://dx.doi.org/10.1038/s41375-020-0759-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7449868PMC
September 2020

Evaluation of circulating cell-free DNA as a molecular monitoring tool in patients with metastatic cancer.

Oncol Lett 2020 Feb 9;19(2):1551-1558. Epub 2019 Dec 9.

IIIrd Medical Department with Hematology and Medical Oncology, Oncologic Center, Paracelsus Medical University Salzburg, A-5020 Salzburg, Austria.

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http://dx.doi.org/10.3892/ol.2019.11192DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6956108PMC
February 2020

C-Reactive Protein and Neutrophil/Lymphocytes Ratio: Prognostic Indicator for Doubling overall survival Prediction in Pancreatic Cancer Patients.

J Clin Med 2019 Oct 25;8(11). Epub 2019 Oct 25.

rd Medical Department with Hematology and Medical Oncology, Hemostaseology, Rheumatology and Infectious Diseases, Paracelsus Medical University, 5071 Salzburg, Austria.

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http://dx.doi.org/10.3390/jcm8111791DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6912559PMC
October 2019

B-cell-specific IRF4 deletion accelerates chronic lymphocytic leukemia development by enhanced tumor immune evasion.

Blood 2019 11;134(20):1717-1729

Department of Internal Medicine III with Haematology, Medical Oncology, Haemostaseology, Infectiology and Rheumatology, Oncologic Center, Paracelsus Medical University, Salzburg, Austria.

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http://dx.doi.org/10.1182/blood.2019000973DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6895374PMC
November 2019

Durable remissions with venetoclax monotherapy in secondary AML refractory to hypomethylating agents and high expression of BCL-2 and/or BIM.

Eur J Haematol 2019 May 28;102(5):437-441. Epub 2019 Feb 28.

Department of Internal Medicine III with Haematology, Medical Oncology, Haemostaseology, Infectiology and Rheumatology, Oncologic Center, Salzburg Cancer Research Institute - Laboratory for Immunological and Molecular Cancer Research (SCRI-LIMCR), Cancer Cluster Salzburg, Paracelsus Medical University, Salzburg, Austria.

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http://dx.doi.org/10.1111/ejh.13218DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6849823PMC
May 2019

BIRC3 Expression Predicts CLL Progression and Defines Treatment Sensitivity via Enhanced NF-κB Nuclear Translocation.

Clin Cancer Res 2019 03 28;25(6):1901-1912. Epub 2018 Nov 28.

Department of Internal Medicine III with Haematology, Medical Oncology, Haemostaseology, Infectiology and Rheumatology, Oncologic Center, Paracelsus Medical University, Salzburg, Austria.

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http://dx.doi.org/10.1158/1078-0432.CCR-18-1548DOI Listing
March 2019

Novel models for prediction of benefit and toxicity with FOLFIRINOX treatment of pancreatic cancer using clinically available parameters.

PLoS One 2018 9;13(11):e0206688. Epub 2018 Nov 9.

IIIrd Medical Department with Hematology and Medical Oncology, Hemostaseology, Rheumatology and Infectious Diseases, Oncologic Center, Paracelsus Medical University, Salzburg, Austria.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0206688PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6226156PMC
April 2019

Exome sequencing of the TCL1 mouse model for CLL reveals genetic heterogeneity and dynamics during disease development.

Leukemia 2019 04 27;33(4):957-968. Epub 2018 Sep 27.

Department of Internal Medicine III with Haematology, Medical Oncology, Haemostaseology, Infectiology and Rheumatology, Oncologic Center, Paracelsus Medical University, Salzburg, Austria.

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http://dx.doi.org/10.1038/s41375-018-0260-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6477797PMC
April 2019

Remission maintenance treatment options in chronic lymphocytic leukemia.

Cancer Treat Rev 2018 Nov 10;70:56-66. Epub 2018 Aug 10.

Department of Internal Medicine III with Hematology, Medical Oncology, Hemostaseology, Infectious Disease, Rheumatology, Oncologic Center, Laboratory for Immunological and Molecular Cancer Research, Paracelsus Medical University Salzburg, Austria; Salzburg Cancer Research Institute and Cancer Cluster Salzburg, Austria. Electronic address:

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http://dx.doi.org/10.1016/j.ctrv.2018.08.003DOI Listing
November 2018

Plitidepsin: a potential new treatment for relapsed/refractory multiple myeloma.

Future Oncol 2019 Jan 16;15(2):109-120. Epub 2018 Aug 16.

Department of Internal Medicine III with Haematology, Medical Oncology, Haemostaseology, Infectiology & Rheumatology, Oncologic Center, Salzburg Cancer Research Institute - Laboratory of Immunological & Molecular Cancer Research (SCRI-LIMCR), Paracelsus Medical University, Salzburg, Austria, Cancer Cluster Salzburg, Austria.

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http://dx.doi.org/10.2217/fon-2018-0492DOI Listing
January 2019

DNA Methylation Signatures Predicting Bevacizumab Efficacy in Metastatic Breast Cancer.

Theranostics 2018 11;8(8):2278-2288. Epub 2018 Mar 11.

III rd Medical Department with Hematology, Medical Oncology, Hemostaseology, Infectious Diseases and Rheumatology, Oncologic Center; Salzburg Cancer Research Institute (SCRI) with Laboratory of Immunological and Molecular Cancer Research (LIMCR) and Center for Clinical Cancer and Immunology Trials (CCCIT); Paracelsus Medical University Salzburg, Salzburg, Austria.

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http://dx.doi.org/10.7150/thno.23544DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5928889PMC
April 2019

Clonal evolution and heterogeneity in metastatic head and neck cancer-An analysis of the Austrian Study Group of Medical Tumour Therapy study group.

Eur J Cancer 2018 04 20;93:69-78. Epub 2018 Mar 20.

IIIrd Medical Department with Hematology and Medical Oncology, Paracelsus Medical University Salzburg, Salzburg, Austria; Salzburg Cancer Research Institute, Salzburg, Austria; Cancer Cluster Salzburg, Salzburg, Austria. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S09598049183007
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http://dx.doi.org/10.1016/j.ejca.2018.01.064DOI Listing
April 2018

Establishment and validation of a novel risk model for estimating time to first treatment in 120 patients with chronic myelomonocytic leukaemia.

Wien Klin Wochenschr 2018 Feb 30;130(3-4):115-125. Epub 2018 Jan 30.

Department of Internal Medicine III with Hematology, Medical Oncology, Hemostaseology, Infectious Disease, Rheumatology, Oncologic Center, Laboratory of Immunological and Molecular Cancer Research, Paracelsus Medical University Salzburg, Muellner Hauptstraße 48, 5020, Salzburg, Austria.

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http://dx.doi.org/10.1007/s00508-018-1315-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5816094PMC
February 2018

Microenvironment-induced CD44v6 promotes early disease progression in chronic lymphocytic leukemia.

Blood 2018 03 19;131(12):1337-1349. Epub 2018 Jan 19.

Third Medical Department with Hematology, Medical Oncology, Hemostaseology, Infectious Diseases, and Rheumatology, Oncologic Center, Paracelsus Medical University, Salzburg, Austria.

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http://dx.doi.org/10.1182/blood-2017-08-802462DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5865232PMC
March 2018

TIGIT expressing CD4+T cells represent a tumor-supportive T cell subset in chronic lymphocytic leukemia.

Oncoimmunology 2017 21;7(1):e1371399. Epub 2017 Sep 21.

Department of Internal Medicine III with Haematology, Medical Oncology, Haemostaseology, Infectiology and Rheumatology, Oncologic Center, Paracelsus Medical University, Salzburg, Austria.

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http://dx.doi.org/10.1080/2162402X.2017.1371399DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5739567PMC
September 2017

Update on squamous cell carcinoma of the head and neck: ASCO annual meeting 2017.

Memo 2017 20;10(4):220-223. Epub 2017 Oct 20.

Third Medical Department with Hematology and Medical Oncology, Paracelsus Medical University Salzburg, Müllner Hauptstraße 48, 5020 Salzburg, Austria.

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http://dx.doi.org/10.1007/s12254-017-0358-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5725515PMC
October 2017

Milestones in Chronic Lymphocytic Leukemia: An exciting decade of progress-10th anniversary of .

Authors:
Alexander Egle

Memo 2017 27;10(1):8-12. Epub 2017 Feb 27.

3rd Medical Department, Paracelsus Private Medical University Hospital Salzburg, Muellnerhauptstrasse 48, 5020 Salzburg, Austria.

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http://dx.doi.org/10.1007/s12254-017-0318-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5357250PMC
February 2017

A phase 2 study of rituximab plus lenalidomide for mucosa-associated lymphoid tissue lymphoma.

Blood 2017 01 22;129(3):383-385. Epub 2016 Nov 22.

Clinical Division of Oncology, Department of Internal Medicine I, Medical University of Vienna, Vienna, Austria.

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http://dx.doi.org/10.1182/blood-2016-06-720599DOI Listing
January 2017

Intermittent low-dose bevacizumab in hereditary hemorrhagic telangiectasia : A case report.

Wien Klin Wochenschr 2017 Feb;129(3-4):141-144

IIIrd Medical Department with Haematology, Medical Oncology, Haemostaseology, Infectious Diseases and Rheumathology, Oncologic Center, Paracelsus Medical University, Muellner Hauptstraße 48, 5020, Salzburg, Austria.

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http://dx.doi.org/10.1007/s00508-016-1124-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5318479PMC
February 2017

CD1d expression on chronic lymphocytic leukemia B cells affects disease progression and induces T cell skewing in CD8 positive and CD4CD8 double negative T cells.

Oncotarget 2016 Aug;7(31):49459-49469

Laboratory for Immunological and Molecular Cancer Research, Department of Internal Medicine III with Haematology, Medical Oncology, Haemostaseology, Infectiology and Rheumatology, Oncologic Center, Paracelsus Medical University, Salzburg, Austria.

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http://dx.doi.org/10.18632/oncotarget.10372DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5226521PMC
August 2016

Fluorouracil and Dihydropyrimidine Dehydrogenase Genotyping.

J Clin Oncol 2016 07 9;34(20):2433-4. Epub 2016 May 9.

Paracelsus Medical University Salzburg; Salzburg Cancer Research Institute; and Cancer Cluster Salzburg, Salzburg, Austria.

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http://dx.doi.org/10.1200/JCO.2016.66.6057DOI Listing
July 2016

Bcl-2 proteins in development, health, and disease of the hematopoietic system.

FEBS J 2016 08 21;283(15):2779-810. Epub 2016 Mar 21.

Division of Pediatric Hematology and Oncology, Department of Pediatrics and Adolescent Medicine, University Medical Center of Freiburg, Germany.

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http://dx.doi.org/10.1111/febs.13683DOI Listing
August 2016

ILK Induction in Lymphoid Organs by a TNFα-NF-κB-Regulated Pathway Promotes the Development of Chronic Lymphocytic Leukemia.

Cancer Res 2016 04 2;76(8):2186-96. Epub 2016 Feb 2.

Third Medical Department with Hematology, Medical Oncology, Hemostaseology, Infectious Diseases, and Rheumatology, Laboratory for Immunological and Molecular Cancer Research, Oncologic Center, Paracelsus Medical University, Salzburg, Austria. Salzburg Cancer Research Institute, Salzburg, Austria.

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http://dx.doi.org/10.1158/0008-5472.CAN-15-3379DOI Listing
April 2016

Anti-Hu Antibody Associated Paraneoplastic Cerebellar Degeneration in Head and Neck Cancer.

BMC Cancer 2015 Dec 22;15:996. Epub 2015 Dec 22.

Third Medical Department with Hematology, Medical Oncology, Hemostaseology, Infectious Diseases and Rheumatology, Oncologic Center, Salzburg Cancer Research Institute with Laboratory of Immunological and Molecular Cancer Research and Center for Clinical Cancer and Immunology Trials, Paracelsus Medical University Salzburg, Muellner Hauptstrasse 48, 5020, Salzburg, Austria.

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http://dx.doi.org/10.1186/s12885-015-2020-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4687318PMC
December 2015

Independent Prognostic Value of Serum Markers in Diffuse Large B-Cell Lymphoma in the Era of the NCCN-IPI.

J Natl Compr Canc Netw 2015 Dec;13(12):1501-8

From the Department of Internal Medicine III, Cancer Research Institute, Paracelsus Medical University Salzburg, Salzburg, Austria; Division of Hematology, Medical University of Graz, Graz, Austria; Institute of Pathology, Paracelsus Medical University Salzburg, Salzburg, Austria; and Department of Experimental Therapeutics, The University of Texas MD Anderson Cancer Center, Duarte, Texas.

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http://www.jnccn.org/content/13/12/1501.full.pdf
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http://dx.doi.org/10.6004/jnccn.2015.0178DOI Listing
December 2015

Ropeginterferon alfa-2b, a novel IFNα-2b, induces high response rates with low toxicity in patients with polycythemia vera.

Blood 2015 Oct 10;126(15):1762-9. Epub 2015 Aug 10.

Laboratory for Immunological and Molecular Cancer Research, Department of Internal Medicine III with Hematology, Medical Oncology, Hemostaseology, Infectious Diseases, Rheumatology, Oncologic Center, Paracelsus Medical University, Salzburg, Austria; and.

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http://dx.doi.org/10.1182/blood-2015-04-637280DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4608390PMC
October 2015

The AKT1 isoform plays a dominant role in the survival and chemoresistance of chronic lymphocytic leukaemia cells.

Br J Haematol 2016 Mar 6;172(5):815-9. Epub 2015 Jul 6.

Laboratory for Immunological and Molecular Cancer Research, 3rd Medical Department with Haematology, Medical Oncology, Haemostaseology, Infectiology and Rheumatology, Oncological Centre, Paracelsus Medical University, Salzburg, Austria.

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http://dx.doi.org/10.1111/bjh.13542DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4832298PMC
March 2016

Chronic lymphocytic leukaemia induces an exhausted T cell phenotype in the TCL1 transgenic mouse model.

Br J Haematol 2015 Aug 4;170(4):515-22. Epub 2015 May 4.

Laboratory for Immunological and Molecular Cancer Research, 3rd Medical Department with Haematology, Medical Oncology, Haemostaseology, Infectiology and Rheumatology, Oncologic Centre, Paracelsus Medical University, Salzburg, Austria.

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http://dx.doi.org/10.1111/bjh.13467DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4687418PMC
August 2015

B-cell receptor usage correlates with the sensitivity to CD40 stimulation and the occurrence of CD4+ T-cell clonality in chronic lymphocytic leukemia.

Haematologica 2015 Aug 24;100(8):e307-10. Epub 2015 Apr 24.

Laboratory for Immunological and Molecular Cancer Research, 3 Medical Department with Hematology, Medical Oncology, Hemostaseology, Infectious Diseases and Rheumatology, Oncologic Center, Paracelsus Medical University Salzburg, Austria Salzburg Cancer Research Institute, Austria.

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http://dx.doi.org/10.3324/haematol.2015.124719DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5004431PMC
August 2015

CXCL12-induced VLA-4 activation is impaired in trisomy 12 chronic lymphocytic leukemia cells: a role for CCL21.

Oncotarget 2015 May;6(14):12048-60

Laboratory for Immunological and Molecular Cancer Research, 3rd Medical Department with Hematology, Medical Oncology, Hemostaseology, Infectious Diseases and Rheumatology, Oncologic Center, Paracelsus Medical University Salzburg, Austria.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4494922PMC
http://dx.doi.org/10.18632/oncotarget.3660DOI Listing
May 2015

Lessons from gain- and loss-of-function models of pro-survival Bcl2 family proteins: implications for targeted therapy.

FEBS J 2015 Mar 23;282(5):834-849. Epub 2015 Jan 23.

Division of Developmental Immunology, Biocenter, Medical University Innsbruck, Austria.

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http://doi.wiley.com/10.1111/febs.13188
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http://dx.doi.org/10.1111/febs.13188DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4562365PMC
March 2015

How does lenalidomide target the chronic lymphocytic leukemia microenvironment?

Blood 2014 Oct 26;124(14):2184-9. Epub 2014 Aug 26.

Department of Haemato-Oncology, Division of Cancer Studies, Faculty of Life Sciences & Medicine, King's College London, London, United Kingdom.

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http://dx.doi.org/10.1182/blood-2014-05-578286DOI Listing
October 2014

Old and new news in CLL: "It's the pathway, stupid!".

Authors:
Alexander Egle

Blood 2014 Aug;124(7):989-90

PARACELSUS MEDICAL UNIVERSITY OF SALZBURG.

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http://dx.doi.org/10.1182/blood-2014-05-574145DOI Listing
August 2014

Kasabach-Merritt phenomenon in hepatic angiosarcoma.

Br J Haematol 2014 Dec 24;167(5):716-8. Epub 2014 Jul 24.

IIIrd Medical Department, Paracelsus Medical University, Salzburg, Austria.

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http://dx.doi.org/10.1111/bjh.13049DOI Listing
December 2014

Treatment of aggressive B-cell lymphoma in elderly patients: influence of single nucleotide polymorphisms affecting pharmacodynamics of chemotherapeutics.

Leuk Lymphoma 2015 Feb 25;56(2):353-60. Epub 2014 Jun 25.

Department of Internal Medicine III with Hematology, Medical Oncology, Hemostaseology, Infectious Disease, Rheumatology, Oncologic Center, Laboratory for Immunological and Molecular Cancer Research, Paracelsus Medical University Salzburg , Austria.

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http://dx.doi.org/10.3109/10428194.2014.916798DOI Listing
February 2015

Liver toxicity during temozolomide chemotherapy caused by Chinese herbs.

BMC Complement Altern Med 2014 Mar 30;14:115. Epub 2014 Mar 30.

Department of Internal Medicine III, Salzburg Cancer Research Institute, Paracelsus Medical University Salzburg, Austria, Müllner-Hauptstrasse 48, Salzburg 5020, Austria.

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http://dx.doi.org/10.1186/1472-6882-14-115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3994275PMC
March 2014

Human immunodeficiency virus type 2 infections in Austria.

Wien Klin Wochenschr 2014 Apr 18;126(7-8):212-6. Epub 2014 Jan 18.

Department of Internal Medicine III with Hematology, Medical Oncology, Hemostaseology, Infectious Diseases, Rheumatology, Oncologic Center, Laboratory for Immunological and Molecular Cancer Research, Paracelsus Medical University Hospital Salzburg, Muellner Hauptstrasse 48, 5020, Salzburg, Austria,

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http://dx.doi.org/10.1007/s00508-013-0493-1DOI Listing
April 2014

Lenalidomide in combination with vorinostat and dexamethasone for the treatment of relapsed/refractory peripheral T cell lymphoma (PTCL): report of a phase I/II trial.

Ann Hematol 2014 Mar 18;93(3):459-62. Epub 2014 Jan 18.

Department of Internal Medicine III with Hematology, Medical Oncology, Hemostaseology, Infectious Disease, Rheumatology, Oncologic Center, Laboratory for Immunological and Molecular Cancer Research, Salzburger Landeskliniken, Paracelsus Medical University Salzburg, Müllner Hauptstrasse 48, 5020, Salzburg, Austria,

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http://dx.doi.org/10.1007/s00277-014-2009-0DOI Listing
March 2014

Pleural decortication of a marginal zone lymphoma.

Ann Hematol 2014 Jul 22;93(7):1253-4. Epub 2013 Nov 22.

Department of Internal Medicine III, Salzburg Cancer Research Institute, Paracelsus Medical University, Müllner-Hauptstrasse 48, 5020, Salzburg, Austria.

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http://search.proquest.com/openview/1250c13ecd37cf51a400e18e
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http://link.springer.com/10.1007/s00277-013-1960-5
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http://dx.doi.org/10.1007/s00277-013-1960-5DOI Listing
July 2014

Complications of 5-azacytidine: Three cases of severe ischemic colitis in elderly patients with myelodysplastic syndrome.

Oncol Lett 2013 Dec 15;6(6):1756-1758. Epub 2013 Oct 15.

Department of Internal Medicine III with Hematology, Medical Oncology, Hemostaseology, Infectious Disease and Rheumatology, Oncological Center, Laboratory for Immunological and Molecular Cancer Research, Paracelsus Medical University of Salzburg, Salzburg A-5020, Austria.

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https://www.spandidos-publications.com/10.3892/ol.2013.1629
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http://dx.doi.org/10.3892/ol.2013.1629DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3834563PMC
December 2013

Viral infections and their management in patients with chronic lymphocytic leukemia.

Leuk Lymphoma 2013 Aug 3;54(8):1602-13. Epub 2013 Jan 3.

Third Medical Department of Hematology, Medical Oncology, Hemostaseology, Rheumatology and Infectiology, Paracelsus Medical University and Laboratory for Immunological and Molecular Cancer Research (LIMCR), Salzburg, Austria.

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http://dx.doi.org/10.3109/10428194.2012.755178DOI Listing
August 2013

Lysine residue at position 22 of the AID protein regulates its class switch activity.

PLoS One 2012 20;7(2):e30667. Epub 2012 Feb 20.

Laboratory for Immunological and Molecular Cancer Research, IIIrd Medical Department with Hematology, Medical Oncology, Hemostaseology, Rheumatology and Infectiology, Paracelsus Medical University Salzburg, Salzburg, Austria.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0030667PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3282692PMC
June 2012

Differential bone marrow homing capacity of VLA-4 and CD38 high expressing chronic lymphocytic leukemia cells.

PLoS One 2011 18;6(8):e23758. Epub 2011 Aug 18.

Laboratory for Immunological and Molecular Cancer Research, Third Medical Department with Hematology, Oncology, Hemostaseology, Infectiology and Rheumatology, Private Medical University Hospital, Salzburg, Austria.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0023758PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3158106PMC
December 2011

Complete remission of Waldenström macroglobulinemia with azacitidine and rituximab.

J Clin Oncol 2011 Aug 5;29(24):e696-8. Epub 2011 Jul 5.

University Hospital Salzburg of the Paracelsus Medical University, Salzburg, Austria.

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http://dx.doi.org/10.1200/JCO.2011.35.8283DOI Listing
August 2011

Regulatory T cells predict the time to initial treatment in early stage chronic lymphocytic leukemia.

Cancer 2011 May 18;117(10):2163-9. Epub 2010 Nov 18.

Laboratory for Immunological and Molecular Cancer Research, Third Medical Department With Hematology, Medical Oncology, Hemostaseology, Rheumatology, and Infectious Disease of the Private Medical University Hospital of Salzburg, Salzburg, Austria.

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http://dx.doi.org/10.1002/cncr.25752DOI Listing
May 2011

An uncommon cause of anaemia: Sheehan's syndrome.

Wien Klin Wochenschr 2010 Dec 7;122(23-24):717-9. Epub 2010 Dec 7.

IIIrd Medical Department with Haematology, Medical Oncology, Haemostaseology, Rheumatology, Infectious Disease of the Private Medical University Hospital Laboratory for Immunological and Molecular Cancer Research, Salzburg, Austria.

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http://dx.doi.org/10.1007/s00508-010-1480-4DOI Listing
December 2010

Fludarabine modulates composition and function of the T cell pool in patients with chronic lymphocytic leukaemia.

Cancer Immunol Immunother 2011 Jan 21;60(1):75-85. Epub 2010 Sep 21.

Laboratory for Immunological and Molecular Cancer Research (LIMCR), 3rd Medical Department with Haematology, Medical Oncology, Haemostaseology, Rheumatology and Infectiology, Paracelsus Medical University Salzburg, Muellner Hauptstrasse 48, 5020, Salzburg, Austria.

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http://dx.doi.org/10.1007/s00262-010-0920-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3029666PMC
January 2011

Interdependent regulation of p53 and miR-34a in chronic lymphocytic leukemia.

Cell Cycle 2010 Jul 3;9(14):2764-8. Epub 2010 Jul 3.

Laboratory for Immunological and Molecular Cancer Research, IIIrd Medical Department with Hematology, Medical Oncology, Hemostaseology, Rheumatology and Infectiology of the Paracelsus Medical University Salzburg, Salzburg, Austria.

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July 2010

Riding the 2-edged sword.

Authors:
Alexander Egle

Blood 2010 Jun;115(22):4325-6

University Hospital Salzburg.

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http://dx.doi.org/10.1182/blood-2010-03-272211DOI Listing
June 2010

microRNA-34a expression correlates with MDM2 SNP309 polymorphism and treatment-free survival in chronic lymphocytic leukemia.

Blood 2010 May 20;115(21):4191-7. Epub 2010 Jan 20.

Laboratory for Immunological and Molecular Cancer Research, 3rd Medical Department of Hematology, Medical Oncology, Hemostaseology, Rheumatology and Infectiology, Paracelsus Medical University Salzburg, Salzburg, Austria.

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http://dx.doi.org/10.1182/blood-2009-07-234823DOI Listing
May 2010

Initial evaluation of the Roche COBAS TaqMan HIV-1 v2.0 assay for determining viral load in HIV-infected individuals.

Antivir Ther 2009 ;14(8):1189-93

Third Medical Department, Paracelsus Medical University and Universitätsklinikum Salzburg, Salzburg, Austria.

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http://dx.doi.org/10.3851/IMP1427DOI Listing
March 2010

Novel therapeutics approaches to chronic lymphocytic leukemia based on recent biological insights.

Discov Med 2009 Oct;8(42):157-64

Laboratory for Immunological and Molecular Cancer Research, IIIrd Medical Department with Hematology, Medical Oncology, Hemostaseology, Rheumatology and Infectiology, Paracelsus Medical University, Salzburg 5020, Austria.

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October 2009

Molecular and cellular mechanisms of CLL: novel therapeutic approaches.

Nat Rev Clin Oncol 2009 Jul 2;6(7):405-18. Epub 2009 Jun 2.

Laboratory for Immunological and Molecular Cancer Research and IIIrd Medical Department with Hematology, Medical Oncology, Hemostaseology, Rheumatology and Infectiology, Paracelsus Medical University Salzburg, Salzburg, Austria.

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http://dx.doi.org/10.1038/nrclinonc.2009.72DOI Listing
July 2009

PKCbeta is essential for the development of chronic lymphocytic leukemia in the TCL1 transgenic mouse model: validation of PKCbeta as a therapeutic target in chronic lymphocytic leukemia.

Blood 2009 Mar 23;113(12):2791-4. Epub 2009 Jan 23.

Laboratory for Immunological and Molecular Cancer Research, 3rd Medical Department for Hematology, Oncology, Hemostasiology, Infectious Diseases and Rheumatology, University Hospital Salzburg, Salzburg, Austria.

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http://dx.doi.org/10.1182/blood-2008-06-160713DOI Listing
March 2009

Expression levels of CD38 in T cells predict course of disease in male patients with B-chronic lymphocytic leukemia.

Blood 2006 Nov 6;108(9):2950-6. Epub 2006 Jul 6.

Laboratory of Immunological and Molecular Cancer Research, 3rd Medical Dept at the Salzburg University Hospital, Muellner Hauptstrasse 48, A-5020 Salzburg, Austria.

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http://www.bloodjournal.org/content/108/9/2950.full.pdf
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http://www.bloodjournal.org/cgi/doi/10.1182/blood-2006-03-01
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http://dx.doi.org/10.1182/blood-2006-03-010553DOI Listing
November 2006

Bim is a suppressor of Myc-induced mouse B cell leukemia.

Proc Natl Acad Sci U S A 2004 Apr 12;101(16):6164-9. Epub 2004 Apr 12.

The Walter and Eliza Hall Institute of Medical Research, 1G Royal Parade, Melbourne, Victoria 3050, Australia.

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http://dx.doi.org/10.1073/pnas.0401471101DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC395940PMC
April 2004

VavP-Bcl2 transgenic mice develop follicular lymphoma preceded by germinal center hyperplasia.

Blood 2004 Mar 20;103(6):2276-83. Epub 2003 Nov 20.

Walter and Eliza Hall Institute of Medical Research, Melbourne, Victoria, Australia.

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http://dx.doi.org/10.1182/blood-2003-07-2469DOI Listing
March 2004