Publications by authors named "Alexander Dobrovic"

100Publications

Donor-specific cell-free DNA as a biomarker in liver transplantation: A review.

World J Transplant 2020 Nov;10(11):307-319

Liver Transplant Unit, Austin Health, Heidelberg 3084, VIC, Australia.

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November 2020

NTRK and ALK rearrangements in malignant pleural mesothelioma, pulmonary neuroendocrine tumours and non-small cell lung cancer.

Lung Cancer 2020 08 24;146:154-159. Epub 2020 May 24.

Department of Medical Oncology, Austin Health, Olivia Newton-John Cancer and Wellness Centre, Heidelberg, Victoria, Australia; Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia; Olivia Newton-John Cancer Research Institute, Heidelberg, Victoria, Australia. Electronic address:

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August 2020

Elevated Plasma Levels of Cell-Free DNA During Liver Transplantation Are Associated With Activation of Coagulation.

Liver Transpl 2020 04 28;26(4):602-603. Epub 2020 Feb 28.

Department of Surgery, Austin Health, University of Melbourne, Heidelberg, Victoria, Australia.

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April 2020

A new normalization for Nanostring nCounter gene expression data.

Nucleic Acids Res 2019 07;47(12):6073-6083

Bioinformatics Division, Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria 3052, Australia.

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July 2019

Molecular Genomic Profiling of Melanocytic Nevi.

J Invest Dermatol 2019 08 14;139(8):1762-1768. Epub 2019 Feb 14.

Melanoma Institute Australia, The University of Sydney, New South Wales, Australia; Sydney Medical School, The University of Sydney, Sydney, New South Wales, Australia.

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August 2019

Genomic Analysis of Circulating Tumor DNA Using a Melanoma-Specific UltraSEEK Oncogene Panel.

J Mol Diagn 2019 05 5;21(3):418-426. Epub 2019 Feb 5.

Cancer Research, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia; Department of Pathology, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.

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May 2019

gene: its function and dysregulation in cancer.

J Clin Pathol 2019 Apr 29;72(4):281-284. Epub 2019 Jan 29.

Tissue Pathology and Diagnostic Oncology, Royal Prince Alfred Hospital, Sydney, Australia.

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April 2019

Mismatch Repair Protein Defects and Microsatellite Instability in Malignant Pleural Mesothelioma.

J Thorac Oncol 2018 10 26;13(10):1588-1594. Epub 2018 Jul 26.

Cancer Immuno-Biology Laboratory, Olivia Newton-John Cancer Research Institute, Heidelberg, Victoria, Australia; School of Cancer Medicine, La Trobe University, Heidelberg, Victoria, Australia; Department of Medical Oncology, Olivia Newton-John Cancer and Wellness Centre, Heidelberg, Victoria, Australia. Electronic address:

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October 2018

Adapting an Established Clinical Chemistry Quality Control Measure for Droplet Generation Performance in Digital PCR.

Clin Chem 2018 08 11;64(8):1255-1257. Epub 2018 Jun 11.

Translational Genomics and Epigenomics Laboratory Olivia Newton-John Cancer Research Institute Heidelberg, Victoria, Australia

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August 2018

Somatic mutation in the of Sturge-Weber syndrome.

Neurol Genet 2018 Jun 1;4(3):e236. Epub 2018 May 1.

Department of Medicine (Austin Hospital) (M.S.H., J.A.D., Z.Y., L.M., I.E.S., S.F.B.), University of Melbourne, Heidelberg, Victoria, Australia; Murdoch Childrens Research Institute (M.S.H., A.S.H., G.G., K.P., P.J.L., R.J.L.), Parkville, Victoria, Australia; Department of Paediatrics (Royal Children's Hospital) (A.S.H., G.G., K.P., P.J.L., R.J.L., I.E.S.), Department of Pathology (H.D., R.K., A.D), and Department of Medicine (Royal Melbourne Hospital) (E.O., N.C.J.), University of Melbourne, Parkville, Victoria, Australia; Department of Neurology (A.S.H., R.J.L., I.E.S.) and Department of Neurosurgery (W.M.), Royal Children's Hospital, Parkville, Victoria, Australia; Department of Neurosciences (S.M., B.N.) and Neurosurgical Department (M.W.), Lady Cilento Children's Hospital, Brisbane, Queensland, Australia; Translational Genomics and Epigenomics Laboratory (H.D., A.D.), Olivia Newton-John Cancer Research Institute, Heidelberg, Victoria, Australia; School of Cancer Medicine (H.D., A.D.), La Trobe University, Bundoora, Victoria, Australia; Anatomical Pathology (R.K.), Austin Health, Heidelberg, Victoria, Australia; Department of Neuroscience (N.C.J.), Central Clinical School, Monash University, Victoria, Australia; and Department of Neurology (N.C.J.), The Alfred Hospital, Melbourne, Victoria, Australia.

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June 2018

Fresh Frozen Plasma Transfusion Can Confound the Analysis of Circulating Cell-Free DNA.

Clin Chem 2018 04 13;64(4):749-751. Epub 2018 Feb 13.

Translational Genomics and Epigenomics Laboratory Olivia Newton-John Cancer Research Institute Victoria, Australia

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April 2018

In Reply to Leone.

J Thorac Oncol 2018 02;13(2):e22-e23

Olivia Newton-John Cancer and Wellness Center, Heidelberg, Melbourne, Australia; School of Cancer Medicine, La Trobe University, Bundoora, Melbourne, Australia.

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February 2018

White Blood Cell BRCA1 Promoter Methylation Status and Ovarian Cancer Risk: A Perspective.

Ann Intern Med 2018 03 16;168(5):365-366. Epub 2018 Jan 16.

Olivia Newton-John Cancer Research Institute, Heidelberg, La Trobe University, Bundoora, and University of Melbourne, Parkville, Victoria, Australia (A.D.).

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March 2018

Sensitive quantitative detection of somatic mosaic mutation in "double cortex" syndrome.

Epileptic Disord 2017 Dec;19(4):450-455

Epilepsy Research Centre, Department of Medicine, University of Melbourne, Austin Health, Heidelberg, VIC.

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December 2017

LRH-1 expression patterns in breast cancer tissues are associated with tumour aggressiveness.

Oncotarget 2017 Oct 28;8(48):83626-83636. Epub 2017 Jul 28.

Department of Pathology, Peter MacCallum Cancer Centre, Victorian Comprehensive Cancer Centre, Melbourne, VIC 3000, Australia.

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October 2017

GRIDSS: sensitive and specific genomic rearrangement detection using positional de Bruijn graph assembly.

Genome Res 2017 12 2;27(12):2050-2060. Epub 2017 Nov 2.

Bioinformatics Division, Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, 3052, Australia.

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December 2017

DNA Breathing Enables Closed-Tube Mutant Allele Enrichment for Circulating Tumor DNA Analysis.

Clin Chem 2017 10 13;63(10):e1-e3. Epub 2017 Sep 13.

Translational Genomics and Epigenomics Laboratory, Olivia Newton-John Cancer Research Institute, Heidelberg, Victoria, Australia;

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October 2017

BRCA2 carriers with male breast cancer show elevated tumour methylation.

BMC Cancer 2017 09 11;17(1):641. Epub 2017 Sep 11.

Molecular Pathology Research and Development Laboratory, Department of Pathology, Peter MacCallum Cancer Centre, Melbourne, VIC, 3000, Australia.

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September 2017

Combination Osimertinib and Gefitinib in C797S and T790M EGFR-Mutated Non-Small Cell Lung Cancer.

J Thorac Oncol 2017 11 24;12(11):1728-1732. Epub 2017 Aug 24.

Cancer Immunobiology Laboratory, Olivia Newton-John Cancer Research Institute, Heidelberg, Victoria, Australia; School of Cancer Medicine, La Trobe University, Bundoora, Victoria, Australia; Department of Medical Oncology, Olivia Newton-John Cancer and Wellness Centre, Austin Health, Heidelberg, Victoria, Australia. Electronic address:

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November 2017

Reducing Artifactual T790M Mutations in DNA from Formalin-Fixed Paraffin-Embedded Tissue by Use of Thymine-DNA Glycosylase.

Clin Chem 2017 Sep 18;63(9):1506-1514. Epub 2017 Jul 18.

Translational Genomics and Epigenomics Laboratory, Olivia Newton-John Cancer Research Institute, Melbourne, Australia;

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September 2017

Assessing alternative base substitutions at primer CpG sites to optimise unbiased PCR amplification of methylated sequences.

Clin Epigenetics 2017 4;9:31. Epub 2017 Apr 4.

Department of Pathology, The University of Melbourne, Parkville, Victoria 3010 Australia.

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December 2017

Evaluation of Different Oligonucleotide Base Substitutions at CpG Binding sites in Multiplex Bisulfite-PCR sequencing.

Sci Rep 2017 03 22;7:45096. Epub 2017 Mar 22.

Centre for Personalised Nanomedicine, Australian Institute for Nanoengineering and Biotechnology, University of Queensland, Brisbane, Australia.

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March 2017

Probe-Free Digital PCR Quantitative Methodology to Measure Donor-Specific Cell-Free DNA after Solid-Organ Transplantation.

Clin Chem 2017 03 18;63(3):742-750. Epub 2017 Jan 18.

Translational Genomics and Epigenomics Laboratory, Olivia Newton-John Cancer Research Institute, Heidelberg, Victoria, Australia;

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March 2017

Digital PCR of Genomic Rearrangements for Monitoring Circulating Tumour DNA.

Adv Exp Med Biol 2016 ;924:139-146

Translational Genomics and Epigenomics Laboratory, Olivia Newton-John Cancer Research Institute, Melbourne, VIC, 3084, Australia.

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September 2017

Genome-scale methylation assessment did not identify prognostic biomarkers in oral tongue carcinomas.

Clin Epigenetics 2016 18;8:74. Epub 2016 Jul 18.

Department of Medical Oncology, Peter MacCallum Cancer Centre, Victorian Comprehensive Cancer Centre Building, 305 Grattan St, Melbourne, Victoria 3000 Australia.

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December 2016

Temporal changes of EGFR mutations and T790M levels in tumour and plasma DNA following AZD9291 treatment.

Lung Cancer 2016 08 11;98:29-32. Epub 2016 May 11.

Department of Medical Oncology, Austin Health, Melbourne, Australia; Olivia Newton-John Cancer Research Institute, Austin Health, Melbourne, Australia.

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August 2016

Comparison of 3 Methodologies for Genotyping of Small Deletion and Insertion Polymorphisms.

Clin Chem 2016 Jul;62(7):1012-9

Translational Genomics and Epigenomics Laboratory, Olivia Newton-John Cancer Research Institute, Heidelberg, Victoria, Australia; School of Cancer Medicine, La Trobe University, Victoria, Australia; Department of Pathology, University of Melbourne, Victoria, Australia.

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July 2016

Fc-γ Receptor Polymorphisms, Cetuximab Therapy, and Survival in the NCIC CTG CO.17 Trial of Colorectal Cancer.

Clin Cancer Res 2016 05;22(10):2435-44

Peter MacCallum Cancer Centre and University of Melbourne, Melbourne, Australia. Translational Genomics and Epigenomics Laboratory, Olivia Newton-John Cancer Research Institute, Heidelberg, Victoria, Australia. School of Cancer Medicine, La Trobe University, Bundoora, Victoria, Australia.

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May 2016

MethPat: a tool for the analysis and visualisation of complex methylation patterns obtained by massively parallel sequencing.

BMC Bioinformatics 2016 Feb 24;17:98. Epub 2016 Feb 24.

Translational Genomics and Epigenomics Laboratory, Olivia Newton-John Cancer Research Institute, Heidelberg, Victoria, 3084, Australia.

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February 2016

Exemplary multiplex bisulfite amplicon data used to demonstrate the utility of Methpat.

Gigascience 2015 26;4:55. Epub 2015 Nov 26.

Translational Genomics and Epigenomics Laboratory, Olivia Newton-John Cancer Research Institute, Heidelberg, VIC 3084 Australia ; Department of Pathology, The University of Melbourne, Parkville, VIC 3052 Australia ; Division of Cancer Medicine, La Trobe University, Bundoora, VIC 3086 Australia ; School of Cancer Medicine, La Trobe University, Bundoora, VIC 3084 Australia.

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July 2016

An optimised direct lysis method for gene expression studies on low cell numbers.

Sci Rep 2015 Aug 5;5:12859. Epub 2015 Aug 5.

1] Translational Genomics &Epigenomics, Olivia Newton-John Cancer Research Institute, Melbourne, Victoria, Australia [2] Department of Pathology, University of Melbourne, Melbourne, Victoria, Australia [3] School of Cancer Medicine, La Trobe University, Melbourne, Victoria, Australia.

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August 2015

Monitoring response to therapy in melanoma by quantifying circulating tumour DNA with droplet digital PCR for BRAF and NRAS mutations.

Sci Rep 2015 Jun 22;5:11198. Epub 2015 Jun 22.

1] Olivia Newton-John Cancer Research Institute, Heidelberg, Victoria, Australia [2] Department of Pathology, University of Melbourne, Parkville, Victoria, Australia [3] School of Cancer Medicine, La Trobe University, Bundoora, Victoria, Australia.

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June 2015

Appraisal of the technologies and review of the genomic landscape of ductal carcinoma in situ of the breast.

Breast Cancer Res 2015 Jun 16;17:80. Epub 2015 Jun 16.

Department of Pathology, Peter MacCallum Cancer Centre, St Andrews Place, East Melbourne, VIC, 3002, Australia.

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June 2015

High-resolution assessment of copy number variation.

Clin Chem 2015 May 3;61(5):684-5. Epub 2015 Apr 3.

Translational Genomics and Epigenomics Laboratory, Olivia Newton-John Cancer Research Institute, Heidelberg, Victoria, Australia; School of Cancer Medicine, La Trobe University, Bundoora, Victoria, Australia; Department of Pathology, University of Melbourne, Parkville, Victoria, Australia.

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May 2015

Heterozygosity for the common perforin mutation, p.A91V, impairs the cytotoxicity of primary natural killer cells from healthy individuals.

Immunol Cell Biol 2015 Jul 17;93(6):575-80. Epub 2015 Mar 17.

1] Cancer Immunology Program, Peter MacCallum Cancer Centre, East Melbourne, Victoria, Australia [2] Sir Peter MacCallum Department of Oncology, Parkville, Victoria, Australia [3] Department of Pathology, University of Melbourne, Parkville, Victoria, Australia [4] Department of Genetics, University of Melbourne, Parkville, Victoria, Australia.

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July 2015

Methylome sequencing in triple-negative breast cancer reveals distinct methylation clusters with prognostic value.

Nat Commun 2015 Feb 2;6:5899. Epub 2015 Feb 2.

1] Epigenetics Group, Cancer Division, Garvan Institute of Medical Research, Sydney, New South Wales 2010, Australia [2] St Vincent's Clinical School, University of NSW, Sydney, New South Wales 2010, Australia.

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February 2015

Whole exome sequencing identifies a recurrent RQCD1 P131L mutation in cutaneous melanoma.

Oncotarget 2015 Jan;6(2):1115-27

Division of Cancer Research, Peter MacCallum Cancer Centre, East Melbourne, Victoria, Australia.Department of Pathology, University of Melbourne, Parkville, Victoria, Australia.

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January 2015

Prevalence and natural history of ALK positive non-small-cell lung cancer and the clinical impact of targeted therapy with ALK inhibitors.

Clin Epidemiol 2014 20;6:423-32. Epub 2014 Nov 20.

Department of Medical Oncology, Olivia-Newton John Cancer and Wellness Centre, Victoria, Australia ; Ludwig Institute for Cancer Research, Austin Health, Victoria, Australia ; School of Cancer Medicine, La Trobe University, Victoria, Australia.

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November 2014

Role of p53 in the progression of gastric cancer.

Oncotarget 2014 Dec;5(23):12016-26

Cancer Genetics and Genomics Laboratory, Peter MacCallum Cancer Centre, East Melbourne, VIC, Australia. Sir Peter MacCallum Department of Oncology, The University of Melbourne, Parkville, VIC, Australia. Department of Medicine, Royal Melbourne Hospital, The University of Melbourne, Parkville, VIC, Australia. Department of Gastroenterology, Royal Melbourne Hospital, Parkville, VIC, Australia.

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December 2014

Sequence artifacts in DNA from formalin-fixed tissues: causes and strategies for minimization.

Clin Chem 2015 Jan 24;61(1):64-71. Epub 2014 Nov 24.

Translational Genomics and Epigenomics Laboratory, Olivia Newton-John Cancer Research Institute, Heidelberg, Victoria, Australia; Department of Pathology, University of Melbourne, Parkville, Victoria, Australia; School of Cancer Medicine, La Trobe University, Bundoora, Victoria, Australia.

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January 2015

Genomic classification of serous ovarian cancer with adjacent borderline differentiates RAS pathway and TP53-mutant tumors and identifies NRAS as an oncogenic driver.

Clin Cancer Res 2014 Dec 14;20(24):6618-30. Epub 2014 Oct 14.

Department of Gynaecological Oncology, Westmead Hospital, Sydney, New South Wales, Australia. Crown Princess Mary Cancer Centre, Westmead Hospital, Sydney, New South Wales, Australia. University of Sydney, Westmead Hospital, Sydney, New South Wales, Australia. Westmead Institute for Cancer Research, Westmead Millennium Institute, Westmead Hospital, Sydney, New South Wales, Australia.

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December 2014

DNA ligase-based strategy for quantifying heterogeneous DNA methylation without sequencing.

Clin Chem 2015 Jan 1;61(1):163-71. Epub 2014 Oct 1.

Centre for Personalized Nanomedicine, Australian Institute for Bioengineering and Nanotechnology (AIBN), and School of Chemistry and Molecular Biosciences, The University of Queensland, St Lucia, Queensland, Australia;

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January 2015

Clinical and pathological associations of the activating RAC1 P29S mutation in primary cutaneous melanoma.

Pigment Cell Melanoma Res 2014 Nov 4;27(6):1117-25. Epub 2014 Aug 4.

Victorian Melanoma Service, Alfred Hospital, Melbourne, Vic., Australia; Department of Epidemiology and Preventive Medicine, Monash University, Melbourne, Vic., Australia; Sir Peter MacCallum Department of Oncology, The University of Melbourne, Parkville, Vic., Australia.

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November 2014

Mapping of actionable mutations to histological subtype domains in lung adenocarcinoma: implications for precision medicine.

Oncotarget 2014 Apr;5(8):2107-15

Translational Genomics and Epigenomics Laboratory Ludwig Institute for Cancer Research Olivia Newton-John Cancer and Wellness Centre Heidelberg, Victoria, Australia.

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April 2014

The clinical relevance of pathologic subtypes in metastatic lung adenocarcinoma.

J Thorac Oncol 2014 May;9(5):654-63

*Department of Medical Oncology, St. Vincent's Hospital, Melbourne; †Department of Medicine, University of Melbourne; ‡Translational Genomics and Epigenomics Laboratory, Ludwig Institute for Cancer Research, Olivia Newton John Cancer and Wellness Centre, Heidelberg; §Department of Pathology, University of Melbourne; ‖Department of Medicine, Eastern Hill Academic Centre, Melbourne Medical School, Faculty of Medicine, Dentistry and Health Sciences, University of Melbourne; ¶Department of Respiratory Medicine, St. Vincent's Hospital; #Department of Thoracic Surgery, St. Vincent's Hospital, Melbourne; **Department of Surgery, University of Melbourne; and ††Department of Anatomical Pathology, St. Vincent's Hospital, Melbourne, Australia.

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May 2014

A critical re-assessment of DNA repair gene promoter methylation in non-small cell lung carcinoma.

Sci Rep 2014 Feb 26;4:4186. Epub 2014 Feb 26.

1] Molecular Pathology Research and Development Laboratory, Department of Pathology, Peter MacCallum Cancer Centre, Melbourne, Victoria, 8006, Australia [2] Translational Genomics and Epigenomics Laboratory, Ludwig Institute for Medical Research, Olivia Newton-John Cancer and Wellness Centre, Austin Hospital, Heidelberg, Victoria, 3084, Australia [3] Sir Peter MacCallum Department of Oncology, University of Melbourne, Parkville, Victoria, 3010, Australia [4] Division of Cancer Medicine, Peter MacCallum Cancer Centre, Melbourne, Victoria, 8006, Australia [5] Department of Pathology, University of Melbourne, Parkville, Victoria, 3010, Australia.

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February 2014

Nuclear HIF1A expression is strongly prognostic in sporadic but not familial male breast cancer.

Mod Pathol 2014 09 24;27(9):1223-30. Epub 2014 Jan 24.

1] Department of Pathology, Peter MacCallum Cancer Center, Melbourne, Australia [2] Department of Pathology and the Sir Peter MacCallum Department of Oncology, University of Melbourne, Melbourne, Australia.

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September 2014

Differential mechanisms of CDKN2A (p16) alteration in oral tongue squamous cell carcinomas and correlation with patient outcome.

Int J Cancer 2014 Aug 30;135(4):887-95. Epub 2014 Jan 30.

Department of Medical Oncology, Peter MacCallum Cancer Centre, East Melbourne, Australia; University of Melbourne, Australia; Research Division, Peter MacCallum Cancer Centre, East Melbourne, Australia.

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August 2014

Quantitative methodology is critical for assessing DNA methylation and impacts on correlation with patient outcome.

Clin Epigenetics 2014 9;6(1):22. Epub 2014 Dec 9.

Translational Genomics and Epigenomics Laboratory, Ludwig Institute for Cancer Research, Olivia Newton-John Cancer & Wellness Centre, Austin Health, 145-163 Studley Road, Heidelberg, Victoria 3084 Australia ; Department of Pathology, Peter MacCallum Cancer Centre, Locked Bag 1 A'Beckett Street, Melbourne, Victoria 8006 Australia ; Department of Pathology, The University of Melbourne, Parkville, Victoria 3010 Australia ; School of Cancer Medicine, La Trobe University, Bundoora, Victoria 3084 Australia.

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April 2015

Targeted-capture massively-parallel sequencing enables robust detection of clinically informative mutations from formalin-fixed tumours.

Sci Rep 2013 Dec 13;3:3494. Epub 2013 Dec 13.

1] Molecular Pathology Research and Development Laboratory, Department of Pathology, Peter MacCallum Cancer Centre, East Melbourne, Victoria, 3002, Australia [2] Department of Pathology, The University of Melbourne, Parkville, Victoria, 3010, Australia [3] Translational Genomics and Epigenomics Laboratory, Ludwig Institute for Cancer Research, The Olivia Newton-John Cancer and Wellness Centre, Heidelberg, Victoria, 3084, Australia.

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December 2013

EGFR gene copy number alterations are not a useful screening tool for predicting EGFR mutation status in lung adenocarcinoma.

Pathology 2014 Jan;46(1):32-6

1Department of Anatomical Pathology, St Vincent's Hospital, University of Melbourne, Fitzroy 2Molecular Pathology Research and Development Laboratory, Department of Pathology, Peter MacCallum Cancer Centre, East Melbourne 3Department of Medical Oncology, St Vincent's Hospital, University of Melbourne, Fitzroy 4University of Melbourne Department of Surgery, St Vincent's Hospital, Fitzroy 5Department of Respiratory and Sleep Medicine, St Vincent's Hospital, University of Melbourne, Fitzroy, Victoria, Australia.

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January 2014

Intratumoral genetic heterogeneity in metastatic melanoma is accompanied by variation in malignant behaviors.

BMC Med Genomics 2013 Oct 11;6:40. Epub 2013 Oct 11.

Cancer Immuno-biology Lab, Ludwig Institute for Cancer Research Melbourne, Austin Branch, Melbourne, Victoria 3084, Australia.

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October 2013

The fusion partner specifies the oncogenic potential of NUP98 fusion proteins.

Leuk Res 2013 Dec 21;37(12):1668-73. Epub 2013 Sep 21.

Division of Blood Cancers, Australian Centre for Blood Diseases, Central Clinical School, Monash University, Melbourne, VIC, Australia.

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December 2013

Reducing sequence artifacts in amplicon-based massively parallel sequencing of formalin-fixed paraffin-embedded DNA by enzymatic depletion of uracil-containing templates.

Clin Chem 2013 Sep 6;59(9):1376-83. Epub 2013 May 6.

Molecular Pathology Research and Development Laboratory, Department of Pathology, Peter MacCallum Cancer Centre, East Melbourne, Victoria, Australia.

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September 2013

Quantitative threefold allele-specific PCR (QuanTAS-PCR) for highly sensitive JAK2 V617F mutant allele detection.

BMC Cancer 2013 Apr 24;13:206. Epub 2013 Apr 24.

Department of Pathology, Peter MacCallum Cancer Centre, St Andrews Place, East Melbourne, Victoria 3002, Australia.

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April 2013

No evidence for PALB2 methylation in high-grade serous ovarian cancer.

J Ovarian Res 2013 Apr 12;6(1):26. Epub 2013 Apr 12.

Molecular Pathology Research and Development Laboratory, Department of Pathology, Peter MacCallum Cancer Centre, East Melbourne, VIC, Australia.

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April 2013

A critical review of the role of Fc gamma receptor polymorphisms in the response to monoclonal antibodies in cancer.

J Hematol Oncol 2013 Jan 4;6. Epub 2013 Jan 4.

Pharmacy Department, Peter MacCallum Cancer Centre, St Andrew's Place, East Melbourne, Victoria, 3002, Australia.

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January 2013

DNA methylation biomarkers in cancer: progress towards clinical implementation.

Expert Rev Mol Diagn 2012 Jun;12(5):473-87

Molecular Pathology Research & Development Laboratory, Department of Pathology, Peter MacCallum Cancer Centre, Locked Bag 1, A'Beckett Street, Melbourne, Victoria 8006, Australia.

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June 2012

Dramatic reduction of sequence artefacts from DNA isolated from formalin-fixed cancer biopsies by treatment with uracil- DNA glycosylase.

Oncotarget 2012 May;3(5):546-58

Molecular Pathology Research and Development Laboratory, Department of Pathology, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.

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May 2012

Methylation profiling of normal individuals reveals mosaic promoter methylation of cancer-associated genes.

Oncotarget 2012 Apr;3(4):450-61

Molecular Pathology Research and Development Laboratory, Department of Pathology, Peter MacCallum Cancer Centre, Melbourne, Australia.

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April 2012

Sensitive quantification of somatic mutations using molecular inversion probes.

Anal Chem 2011 Nov 13;83(21):8215-21. Epub 2011 Oct 13.

Centre for Biomarker Research and Development, Australian Institute for Bioengineering and Nanotechnology (AIBN), The University of Queensland, Brisbane, QLD, Australia.

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November 2011

Closed-tube PCR methods for locus-specific DNA methylation analysis.

Methods Mol Biol 2011 ;791:55-71

Molecular Pathology Research and Development Laboratory, Department of Pathology, Peter MacCallum Cancer Centre, Melbourne, VIC, Australia.

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December 2011

Analysing DNA methylation using bisulphite pyrosequencing.

Methods Mol Biol 2011 ;791:33-53

Molecular Pathology Research and Development Laboratory, Department of Pathology, Peter MacCallum Cancer Centre, Melbourne, VIC, Australia.

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December 2011

Aberrant DNA methylation but not mutation of CITED4 is associated with alteration of HIF-regulated genes in breast cancer.

Breast Cancer Res Treat 2011 Nov 14;130(1):319-29. Epub 2011 Jul 14.

Molecular Pathology Research and Development Laboratory, Department of Pathology, Peter MacCallum Cancer Centre, Melbourne, VIC, 8006, Australia.

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November 2011