Alexander B Meijer

Alexander B Meijer

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Alexander B Meijer

Alexander B Meijer

Publications by authors named "Alexander B Meijer"

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Unique surface-exposed hydrophobic residues in the C1 domain of factor VIII contribute to cofactor function and von Willebrand factor binding.

J Thromb Haemost 2020 Feb 28;18(2):364-372. Epub 2019 Nov 28.

Department of Molecular and Cellular Hemostasis, Sanquin Research, Amsterdam, the Netherlands.

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http://dx.doi.org/10.1111/jth.14668DOI Listing
February 2020

Missing regions within the molecular architecture of human fibrin clots structurally resolved by XL-MS and integrative structural modeling.

Proc Natl Acad Sci U S A 2020 Jan 10;117(4):1976-1987. Epub 2020 Jan 10.

Biomolecular Mass Spectrometry and Proteomics, Bijvoet Center for Biomolecular Research, Utrecht University, 3584 CH Utrecht, The Netherlands;

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http://dx.doi.org/10.1073/pnas.1911785117DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6995014PMC
January 2020

Dynamic Transcriptome-Proteome Correlation Networks Reveal Human Myeloid Differentiation and Neutrophil-Specific Programming.

Cell Rep 2019 Nov;29(8):2505-2519.e4

Department of Blood Cell Research, Sanquin Research, Amsterdam University Medical Center (AUMC), University of Amsterdam, Amsterdam, the Netherlands; Department of Paediatric Immunology and Infectious Diseases, Emma Children's Hospital, AUMC, University of Amsterdam, Amsterdam, the Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2019.10.082DOI Listing
November 2019

D'domain Region Arg782-Cys799 of Von Willebrand Factor contributes to Factor VIII binding.

Haematologica 2019 Sep 26. Epub 2019 Sep 26.

Department of Molecular and Cellular Hemostasis, Sanquin Research, Amsterdam, the Netherlands

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http://dx.doi.org/10.3324/haematol.2019.221994DOI Listing
September 2019

A combined immunodeficiency with severe infections, inflammation, and allergy caused by ARPC1B deficiency.

J Allergy Clin Immunol 2019 Jun 13;143(6):2296-2299. Epub 2019 Feb 13.

Department of Pediatric Immunology, Rheumatology and Infectious Diseases, Emma Children's Hospital, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands; Department of Blood Cell Research, Sanquin Research and Landsteiner Laboratory AMC, University of Amsterdam, Amsterdam, the Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2019.02.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6677392PMC
June 2019

Strap associates with Csde1 and affects expression of select Csde1-bound transcripts.

PLoS One 2018 23;13(8):e0201690. Epub 2018 Aug 23.

Sanquin Research, Department of Hematopoiesis, and Landsteiner Laboratory Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0201690PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6107111PMC
February 2019

Integrated proteomic analysis of tumor necrosis factor α and interleukin 1β-induced endothelial inflammation.

J Proteomics 2019 02 25;192:89-101. Epub 2018 Aug 25.

Department of Molecular and Cellular Hemostasis, Sanquin Research, Amsterdam 1066 CX, the Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.jprot.2018.08.011DOI Listing
February 2019

The D' domain of von Willebrand factor requires the presence of the D3 domain for optimal factor VIII binding.

Biochem J 2018 09 11;475(17):2819-2830. Epub 2018 Sep 11.

Department of Plasma Proteins, Sanquin Research, 1066 CX Amsterdam, The Netherlands

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http://dx.doi.org/10.1042/BCJ20180431DOI Listing
September 2018

Mass spectrometry-assisted identification of ADAMTS13-derived peptides presented on HLA-DR and HLA-DQ.

Haematologica 2018 06 22;103(6):1083-1092. Epub 2018 Mar 22.

Department of Plasma Proteins, Sanquin Research and Landsteiner Laboratory, Academic Medical Center, University of Amsterdam, the Netherlands.

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http://dx.doi.org/10.3324/haematol.2017.179119DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6058777PMC
June 2018

Chemical Footprinting Reveals Conformational Changes Following Activation of Factor XI.

Thromb Haemost 2018 02 29;118(2):340-350. Epub 2018 Jan 29.

Department of Plasma Proteins, Sanquin Research, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1160/TH17-09-0676DOI Listing
February 2018

Comparative profiling of HLA-DR and HLA-DQ associated factor VIII peptides presented by monocyte-derived dendritic cells.

Haematologica 2018 01 12;103(1):172-178. Epub 2017 Oct 12.

Department of Plasma Proteins, Sanquin Research and Landsteiner Laboratory, Academic Medical Center, University of Amsterdam, the Netherlands

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http://dx.doi.org/10.3324/haematol.2017.175083DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5777204PMC
January 2018

Hermansky-Pudlak syndrome type 2: Aberrant pre-mRNA splicing and mislocalization of granule proteins in neutrophils.

Hum Mutat 2017 10 15;38(10):1402-1411. Epub 2017 Jun 15.

Sanquin Research, and Landsteiner Laboratory, Academic Medical Center (AMC), University of Amsterdam, Amsterdam, The Netherlands.

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http://doi.wiley.com/10.1002/humu.23271
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http://dx.doi.org/10.1002/humu.23271DOI Listing
October 2017

Paradigm of Biased PAR1 (Protease-Activated Receptor-1) Activation and Inhibition in Endothelial Cells Dissected by Phosphoproteomics.

Arterioscler Thromb Vasc Biol 2017 10 17;37(10):1891-1902. Epub 2017 Aug 17.

From the Department Plasma Proteins (B.L.v.d.E., A.J.H., P.J.S., K.M., A.B.M., M.v.d.B.), Department of Research Facilities (F.P.J.v.A., A.B.M.), Sanquin Research, Amsterdam, The Netherlands; Tumour Microenvironment and Proteomics Laboratory, Cancer Research UK Beatson Institute, Glasgow, United Kingdom (S.Z.); Tumour Microenvironment and Proteomics Laboratory, Institute of Cancer Sciences, University of Glasgow, United Kingdom (S.Z.); Department Pharmaceutics, Utrecht Institute for Pharmaceutical Sciences (UIPS), Utrecht University, The Netherlands (K.M., A.B.M.).

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http://dx.doi.org/10.1161/ATVBAHA.117.309926DOI Listing
October 2017

Cellular uptake of coagulation factor VIII: Elusive role of the membrane-binding spikes in the C1 domain.

Int J Biochem Cell Biol 2017 08 27;89:34-41. Epub 2017 May 27.

From the Department of Plasma Proteins, Sanquin Research, Amsterdam, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.biocel.2017.05.027DOI Listing
August 2017

Role of glycine 221 in catalytic activity of hyaluronan-binding protein 2.

J Biol Chem 2017 04 27;292(15):6381-6388. Epub 2017 Feb 27.

From the Department of Plasma Proteins, Sanquin Research, 1066 CX Amsterdam, The Netherlands and

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http://dx.doi.org/10.1074/jbc.M116.757849DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5391765PMC
April 2017

Analysis of the HLA-DR peptidome from human dendritic cells reveals high affinity repertoires and nonconventional pathways of peptide generation.

J Leukoc Biol 2017 01 30;101(1):15-27. Epub 2016 Jun 30.

Department of Cell Biology, Physiology and Immunology, Laboratori d'Immunologia Cellular, Institut de Biotecnologia i Biomedicina, Universitat Autònoma de Barcelona, Barcelona, Spain;

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http://dx.doi.org/10.1189/jlb.6HI0216-069RDOI Listing
January 2017

The class I scavenger receptor CD163 promotes internalization of ADAMTS13 by macrophages.

Blood Adv 2017 Jan 16;1(5):293-305. Epub 2017 Jan 16.

Department of Plasma Proteins, Sanquin Research and Landsteiner Laboratory, Academic Medical Center (AMC), University of Amsterdam, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1182/bloodadvances.2016001321DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5744037PMC
January 2017

Identification of glycans on plasma-derived ADAMTS13.

Blood 2016 11 29;128(21):e51-e58. Epub 2016 Aug 29.

Department of Plasma Proteins, Sanquin-Academic Medical Center Landsteiner Laboratory, Amsterdam, The Netherlands.

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http://www.bloodjournal.org/content/early/2016/08/29/blood-2
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http://dx.doi.org/10.1182/blood-2016-06-720912DOI Listing
November 2016

Impaired killing of Candida albicans by granulocytes mobilized for transfusion purposes: a role for granule components.

Haematologica 2016 05 22;101(5):587-96. Epub 2016 Jan 22.

Sanquin Research, and Landsteiner Laboratory, Academic Medical Center, University of Amsterdam, The Netherlands Emma Children's Hospital, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.

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http://www.haematologica.org/cgi/doi/10.3324/haematol.2015.1
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http://dx.doi.org/10.3324/haematol.2015.136630DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5004374PMC
May 2016

Factor VIII Interacts with the Endocytic Receptor Low-density Lipoprotein Receptor-related Protein 1 via an Extended Surface Comprising "Hot-Spot" Lysine Residues.

J Biol Chem 2015 Jul 21;290(27):16463-76. Epub 2015 Apr 21.

From the Department of Plasma Proteins, Sanquin Blood Supply Foundation, 1066 CX Amsterdam, The Netherlands, the Department of Pharmaceutics, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, 3508 TC Utrecht, The Netherlands.

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http://dx.doi.org/10.1074/jbc.M115.650911DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4505400PMC
July 2015

PKCδ is dispensible for oxLDL uptake and foam cell formation by human and murine macrophages.

Cardiovasc Res 2014 Dec 24;104(3):467-76. Epub 2014 Sep 24.

Department of Blood Cell Research, Sanquin Research and Landsteiner Laboratory, Academic Medical Center, University of Amsterdam, Plesmanlaan 125, Amsterdam 1066CX, The Netherlands.

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http://dx.doi.org/10.1093/cvr/cvu213DOI Listing
December 2014

A3 domain region 1803-1818 contributes to the stability of activated factor VIII and includes a binding site for activated factor IX.

J Biol Chem 2013 Sep 24;288(36):26105-11. Epub 2013 Jul 24.

Department of Plasma Proteins, Sanquin Research, 1066 CX Amsterdam, The Netherlands.

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http://dx.doi.org/10.1074/jbc.M113.500884DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3764813PMC
September 2013

Preferential HLA-DRB1*11-dependent presentation of CUB2-derived peptides by ADAMTS13-pulsed dendritic cells.

Blood 2013 Apr 31;121(17):3502-10. Epub 2013 Jan 31.

Department of Plasma Proteins, Sanquin Research, Plesmanlaan 125, Amsterdam, the Netherlands.

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http://dx.doi.org/10.1182/blood-2012-09-456780DOI Listing
April 2013

Potassium leakage primes stored erythrocytes for phosphatidylserine exposure and shedding of pro-coagulant vesicles.

Br J Haematol 2013 Feb 28;160(3):377-86. Epub 2012 Nov 28.

Department of Blood Cell Research, Sanquin Research and Landsteiner Laboratory, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1111/bjh.12133DOI Listing
February 2013

Factors VIII and V swap fatty feet.

Blood 2012 Aug;120(9):1761-3

Sanquin Blood Supply Foundation; Utrecht Institute For Pharmaceutical Sciences.

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http://dx.doi.org/10.1182/blood-2012-07-434027DOI Listing
August 2012

Novel role for galectin-8 protein as mediator of coagulation factor V endocytosis by megakaryocytes.

J Biol Chem 2012 Mar 20;287(11):8327-35. Epub 2012 Jan 20.

Department of Plasma Proteins, Sanquin Research, 1066 CX Amsterdam, The Netherlands.

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http://dx.doi.org/10.1074/jbc.M111.305151DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3318750PMC
March 2012

Uptake of blood coagulation factor VIII by dendritic cells is mediated via its C1 domain.

J Allergy Clin Immunol 2012 Feb 1;129(2):501-9, 509.e1-5. Epub 2011 Oct 1.

Department of Plasma Proteins, Sanquin-AMC Landsteiner Laboratory, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1016/j.jaci.2011.08.029DOI Listing
February 2012

C1 domain residues Lys 2092 and Phe 2093 are of major importance for the endocytic uptake of coagulation factor VIII.

Int J Biochem Cell Biol 2011 Aug 8;43(8):1114-21. Epub 2011 Apr 8.

Department of Plasma Proteins, Sanquin Research, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1016/j.biocel.2011.03.014DOI Listing
August 2011

HLA-DR-presented peptide repertoires derived from human monocyte-derived dendritic cells pulsed with blood coagulation factor VIII.

Mol Cell Proteomics 2011 Jun 5;10(6):M110.002246. Epub 2011 Apr 5.

Department of Plasma Proteins, Van Creveld Laboratory of UMC Utrecht and Sanquin Research, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1074/mcp.M110.002246DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3108829PMC
June 2011

Factor VIII C1 domain residues Lys 2092 and Phe 2093 contribute to membrane binding and cofactor activity.

Blood 2009 Oct 17;114(18):3938-46. Epub 2009 Aug 17.

Department of Plasma Proteins, Sanquin Research, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1182/blood-2009-01-197707DOI Listing
October 2009

Intracellular cotrafficking of factor VIII and von Willebrand factor type 2N variants to storage organelles.

Blood 2009 Mar 16;113(13):3102-9. Epub 2008 Dec 16.

Department of Plasma Proteins, Sanquin Research, Amsterdam, The Netherlands.

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http://www.bloodjournal.org/cgi/doi/10.1182/blood-2008-05-15
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http://dx.doi.org/10.1182/blood-2008-05-159699DOI Listing
March 2009

The binding sites for the very low density lipoprotein receptor and low-density lipoprotein receptor-related protein are shared within coagulation factor VIII.

Blood Coagul Fibrinolysis 2008 Mar;19(2):166-77

Center for Vascular and Inflammatory Diseases, Department of Biochemistry and Molecular Biology, University of Maryland School of Medicine, Baltimore, Maryland, USA.

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https://insights.ovid.com/crossref?an=00001721-200803000-000
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http://dx.doi.org/10.1097/MBC.0b013e3282f5457bDOI Listing
March 2008

Efficient transduction of simian cells by HIV-1-based lentiviral vectors that contain mutations in the capsid protein.

Mol Ther 2007 May 13;15(5):930-7. Epub 2007 Feb 13.

Department of Clinical Viro Immunology, Sanquin Research, Landsteiner Laboratory, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1038/mt.sj.6300091DOI Listing
May 2007

The interface between the EGF2 domain and the protease domain in blood coagulation factor IX contributes to factor VIII binding and factor X activation.

Biochemistry 2006 Sep;45(35):10777-85

Department of Plasma Proteins, Sanquin Research, 1066 CX Amsterdam, The Netherlands.

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http://dx.doi.org/10.1021/bi060451hDOI Listing
September 2006

Expression of myeloperoxidase (MPO) by neutrophils is necessary for their activation by anti-neutrophil cytoplasm autoantibodies (ANCA) against MPO.

J Leukoc Biol 2003 Jun;73(6):841-9

Département d'Hématologie-Immunologie-Cytogénétique, Centre Hospitalier de Valenciennes, France.

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http://dx.doi.org/10.1189/jlb.1102567DOI Listing
June 2003

Low density lipoprotein receptor-related protein and factor IXa share structural requirements for binding to the A3 domain of coagulation factor VIII.

J Biol Chem 2003 Mar 8;278(11):9370-7. Epub 2003 Jan 8.

Department of Plasma Proteins, Sanquin Research at CLB, 1066 CX Amsterdam, The Netherlands.

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http://dx.doi.org/10.1074/jbc.M212053200DOI Listing
March 2003