Alexa Beiser

Alexa Beiser

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Alexa Beiser

Alexa Beiser

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Plasma total-tau as a biomarker of stroke risk in the community.

Ann Neurol 2019 Sep 29;86(3):463-467. Epub 2019 Jul 29.

Framingham Heart Study, Framingham, MA.

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http://dx.doi.org/10.1002/ana.25542DOI Listing
September 2019

Author Correction: Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing.

Authors:
Brian W Kunkle Benjamin Grenier-Boley Rebecca Sims Joshua C Bis Vincent Damotte Adam C Naj Anne Boland Maria Vronskaya Sven J van der Lee Alexandre Amlie-Wolf Céline Bellenguez Aura Frizatti Vincent Chouraki Eden R Martin Kristel Sleegers Nandini Badarinarayan Johanna Jakobsdottir Kara L Hamilton-Nelson Sonia Moreno-Grau Robert Olaso Rachel Raybould Yuning Chen Amanda B Kuzma Mikko Hiltunen Taniesha Morgan Shahzad Ahmad Badri N Vardarajan Jacques Epelbaum Per Hoffmann Merce Boada Gary W Beecham Jean-Guillaume Garnier Denise Harold Annette L Fitzpatrick Otto Valladares Marie-Laure Moutet Amy Gerrish Albert V Smith Liming Qu Delphine Bacq Nicola Denning Xueqiu Jian Yi Zhao Maria Del Zompo Nick C Fox Seung-Hoan Choi Ignacio Mateo Joseph T Hughes Hieab H Adams John Malamon Florentino Sanchez-Garcia Yogen Patel Jennifer A Brody Beth A Dombroski Maria Candida Deniz Naranjo Makrina Daniilidou Gudny Eiriksdottir Shubhabrata Mukherjee David Wallon James Uphill Thor Aspelund Laura B Cantwell Fabienne Garzia Daniela Galimberti Edith Hofer Mariusz Butkiewicz Bertrand Fin Elio Scarpini Chloe Sarnowski Will S Bush Stéphane Meslage Johannes Kornhuber Charles C White Yuenjoo Song Robert C Barber Sebastiaan Engelborghs Sabrina Sordon Dina Voijnovic Perrie M Adams Rik Vandenberghe Manuel Mayhaus L Adrienne Cupples Marilyn S Albert Peter P De Deyn Wei Gu Jayanadra J Himali Duane Beekly Alessio Squassina Annette M Hartmann Adelina Orellana Deborah Blacker Eloy Rodriguez-Rodriguez Simon Lovestone Melissa E Garcia Rachelle S Doody Carmen Munoz-Fernadez Rebecca Sussams Honghuang Lin Thomas J Fairchild Yolanda A Benito Clive Holmes Hata Karamujić-Čomić Matthew P Frosch Hakan Thonberg Wolfgang Maier Gennady Roshchupkin Bernardino Ghetti Vilmantas Giedraitis Amit Kawalia Shuo Li Ryan M Huebinger Lena Kilander Susanne Moebus Isabel Hernández M Ilyas Kamboh RoseMarie Brundin James Turton Qiong Yang Mindy J Katz Letizia Concari Jenny Lord Alexa S Beiser C Dirk Keene Seppo Helisalmi Iwona Kloszewska Walter A Kukull Anne Maria Koivisto Aoibhinn Lynch Lluís Tarraga Eric B Larson Annakaisa Haapasalo Brian Lawlor Thomas H Mosley Richard B Lipton Vincenzo Solfrizzi Michael Gill W T Longstreth Thomas J Montine Vincenza Frisardi Monica Diez-Fairen Fernando Rivadeneira Ronald C Petersen Vincent Deramecourt Ignacio Alvarez Francesca Salani Antonio Ciaramella Eric Boerwinkle Eric M Reiman Nathalie Fievet Jerome I Rotter Joan S Reisch Olivier Hanon Chiara Cupidi A G Andre Uitterlinden Donald R Royall Carole Dufouil Raffaele Giovanni Maletta Itziar de Rojas Mary Sano Alexis Brice Roberta Cecchetti Peter St George-Hyslop Karen Ritchie Magda Tsolaki Debby W Tsuang Bruno Dubois David Craig Chuang-Kuo Wu Hilkka Soininen Despoina Avramidou Roger L Albin Laura Fratiglioni Antonia Germanou Liana G Apostolova Lina Keller Maria Koutroumani Steven E Arnold Francesco Panza Olymbia Gkatzima Sanjay Asthana Didier Hannequin Patrice Whitehead Craig S Atwood Paolo Caffarra Harald Hampel Inés Quintela Ángel Carracedo Lars Lannfelt David C Rubinsztein Lisa L Barnes Florence Pasquier Lutz Frölich Sandra Barral Bernadette McGuinness Thomas G Beach Janet A Johnston James T Becker Peter Passmore Eileen H Bigio Jonathan M Schott Thomas D Bird Jason D Warren Bradley F Boeve Michelle K Lupton James D Bowen Petra Proitsi Adam Boxer John F Powell James R Burke John S K Kauwe Jeffrey M Burns Michelangelo Mancuso Joseph D Buxbaum Ubaldo Bonuccelli Nigel J Cairns Andrew McQuillin Chuanhai Cao Gill Livingston Chris S Carlson Nicholas J Bass Cynthia M Carlsson John Hardy Regina M Carney Jose Bras Minerva M Carrasquillo Rita Guerreiro Mariet Allen Helena C Chui Elizabeth Fisher Carlo Masullo Elizabeth A Crocco Charles DeCarli Gina Bisceglio Malcolm Dick Li Ma Ranjan Duara Neill R Graff-Radford Denis A Evans Angela Hodges Kelley M Faber Martin Scherer Kenneth B Fallon Matthias Riemenschneider David W Fardo Reinhard Heun Martin R Farlow Heike Kölsch Steven Ferris Markus Leber Tatiana M Foroud Isabella Heuser Douglas R Galasko Ina Giegling Marla Gearing Michael Hüll Daniel H Geschwind John R Gilbert John Morris Robert C Green Kevin Mayo John H Growdon Thomas Feulner Ronald L Hamilton Lindy E Harrell Dmitriy Drichel Lawrence S Honig Thomas D Cushion Matthew J Huentelman Paul Hollingworth Christine M Hulette Bradley T Hyman Rachel Marshall Gail P Jarvik Alun Meggy Erin Abner Georgina E Menzies Lee-Way Jin Ganna Leonenko Luis M Real Gyungah R Jun Clinton T Baldwin Detelina Grozeva Anna Karydas Giancarlo Russo Jeffrey A Kaye Ronald Kim Frank Jessen Neil W Kowall Bruno Vellas Joel H Kramer Emma Vardy Frank M LaFerla Karl-Heinz Jöckel James J Lah Martin Dichgans James B Leverenz David Mann Allan I Levey Stuart Pickering-Brown Andrew P Lieberman Norman Klopp Kathryn L Lunetta H-Erich Wichmann Constantine G Lyketsos Kevin Morgan Daniel C Marson Kristelle Brown Frank Martiniuk Christopher Medway Deborah C Mash Markus M Nöthen Eliezer Masliah Nigel M Hooper Wayne C McCormick Antonio Daniele Susan M McCurry Anthony Bayer Andrew N McDavid John Gallacher Ann C McKee Hendrik van den Bussche Marsel Mesulam Carol Brayne Bruce L Miller Steffi Riedel-Heller Carol A Miller Joshua W Miller Ammar Al-Chalabi John C Morris Christopher E Shaw Amanda J Myers Jens Wiltfang Sid O'Bryant John M Olichney Victoria Alvarez Joseph E Parisi Andrew B Singleton Henry L Paulson John Collinge William R Perry Simon Mead Elaine Peskind David H Cribbs Martin Rossor Aimee Pierce Natalie S Ryan Wayne W Poon Benedetta Nacmias Huntington Potter Sandro Sorbi Joseph F Quinn Eleonora Sacchinelli Ashok Raj Gianfranco Spalletta Murray Raskind Carlo Caltagirone Paola Bossù Maria Donata Orfei Barry Reisberg Robert Clarke Christiane Reitz A David Smith John M Ringman Donald Warden Erik D Roberson Gordon Wilcock Ekaterina Rogaeva Amalia Cecilia Bruni Howard J Rosen Maura Gallo Roger N Rosenberg Yoav Ben-Shlomo Mark A Sager Patrizia Mecocci Andrew J Saykin Pau Pastor Michael L Cuccaro Jeffery M Vance Julie A Schneider Lori S Schneider Susan Slifer William W Seeley Amanda G Smith Joshua A Sonnen Salvatore Spina Robert A Stern Russell H Swerdlow Mitchell Tang Rudolph E Tanzi John Q Trojanowski Juan C Troncoso Vivianna M Van Deerlin Linda J Van Eldik Harry V Vinters Jean Paul Vonsattel Sandra Weintraub Kathleen A Welsh-Bohmer Kirk C Wilhelmsen Jennifer Williamson Thomas S Wingo Randall L Woltjer Clinton B Wright Chang-En Yu Lei Yu Yasaman Saba Alberto Pilotto Maria J Bullido Oliver Peters Paul K Crane David Bennett Paola Bosco Eliecer Coto Virginia Boccardi Phil L De Jager Alberto Lleo Nick Warner Oscar L Lopez Martin Ingelsson Panagiotis Deloukas Carlos Cruchaga Caroline Graff Rhian Gwilliam Myriam Fornage Alison M Goate Pascual Sanchez-Juan Patrick G Kehoe Najaf Amin Nilifur Ertekin-Taner Claudine Berr Stéphanie Debette Seth Love Lenore J Launer Steven G Younkin Jean-Francois Dartigues Chris Corcoran M Arfan Ikram Dennis W Dickson Gael Nicolas Dominique Campion JoAnn Tschanz Helena Schmidt Hakon Hakonarson Jordi Clarimon Ron Munger Reinhold Schmidt Lindsay A Farrer Christine Van Broeckhoven Michael C O'Donovan Anita L DeStefano Lesley Jones Jonathan L Haines Jean-Francois Deleuze Michael J Owen Vilmundur Gudnason Richard Mayeux Valentina Escott-Price Bruce M Psaty Alfredo Ramirez Li-San Wang Agustin Ruiz Cornelia M van Duijn Peter A Holmans Sudha Seshadri Julie Williams Phillippe Amouyel Gerard D Schellenberg Jean-Charles Lambert Margaret A Pericak-Vance

Nat Genet 2019 Aug 15. Epub 2019 Aug 15.

John P. Hussman Institute for Human Genomics, University of Miami Miller School of Medicine, Miami, FL, USA.

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http://dx.doi.org/10.1038/s41588-019-0495-7DOI Listing
August 2019

Relationship of Cancer to Brain Aging Markers of Alzheimer's Disease: The Framingham Heart Study.

Adv Geriatr Med Res 2019 4;1. Epub 2019 Jul 4.

New England Geriatric Research Education and Clinical Center, VA Boston Healthcare System, Boston, MA 02130 USA.

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http://dx.doi.org/10.20900/agmr20190006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6659723PMC
July 2019

Temporal Trends in Ischemic Stroke Incidence in Younger Adults in the Framingham Study.

Stroke 2019 Jun 14;50(6):1558-1560. Epub 2019 May 14.

From the Boston University School of Medicine, MA (H.J.A., J.J.H., C.L.S., J.R.R., C.S.K., A.S.B., S.S.).

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http://dx.doi.org/10.1161/STROKEAHA.119.025171DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6538454PMC
June 2019

Distribution of cerebral microbleeds in the East and West: Individual participant meta-analysis.

Neurology 2019 Mar 1;92(10):e1086-e1097. Epub 2019 Feb 1.

From the Stroke Research Center, Department of Brain Repair & Rehabilitation, Institute of Neurology (Y.Y., D.W., A.C., D.J.W.), and Department of Statistical Science (G.A.), UCL, London, UK; Division of Neurology (Y.Y., H.H.), Department of Internal Medicine, Saga University Faculty of Medicine, Japan; Department of Neurology (A.B., S.R.P., J.R.R., S.S., P.A.W.), Boston University and the NHLBI's Framingham Heart Study; Department of Biostatistics (A.B., S.R.P.), Boston University, MA; Department of Radiology (M.A.v.B.), Leiden University Medical Center, the Netherlands; Department of Neurology (C.D.), University of California Davis; Department of Neurology (D.D.), Huashan Hospital, Fudan University, Shanghai, China; Icelandic Heart Association (V.G.), Kopavogur; University of Iceland (V.G.), Reykjavik; Department of Neurosurgery (T.I.), Kushiro City General Hospital; Faculty of Collaborative Regional Innovation (K.K.), Ehime University, Matsuyama, Japan; Department of Neurology (H.-M.K.), SMG-SNU Boramae Medical Center, Seoul, Republic of Korea; Intramural Research Program (L.J.L.), National Institute on Aging, Bethesda, MD; Therese Pei Fong Chow Research Center for Prevention of Dementia (V.M., Z.W., Y.X.), Department of Medicine and Therapeutics, The Chinese University of Hong Kong, China; Stroke and Aging Research Group, Department of Medicine, School of Clinical Science at Monash Health (T.P., V.S.), and Department of Medicine, Peninsula Health and Clinical School, Central Clinical School (V.S.), Monash University, Melbourne, Australia; Center for Emotional and Behavioral Disorders (Y. Takashima), Hizen Psychiatric Center, Saga, Japan; Department of Diagnostic Radiology and Nuclear Medicine (Y. Tsushima), Gunma University Graduate School of Medicine; Research Program for Diagnostic and Molecular Imaging (Y. Tsushima), Division of Integrated Oncology Research, Gunma University Initiative for Advanced Research, Maebashi; and Department of Neurology (S.Y.), Faculty of Medicine, Shimane University, Izumo, Japan.

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http://dx.doi.org/10.1212/WNL.0000000000007039DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6442016PMC
March 2019

Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing.

Authors:
Brian W Kunkle Benjamin Grenier-Boley Rebecca Sims Joshua C Bis Vincent Damotte Adam C Naj Anne Boland Maria Vronskaya Sven J van der Lee Alexandre Amlie-Wolf Céline Bellenguez Aura Frizatti Vincent Chouraki Eden R Martin Kristel Sleegers Nandini Badarinarayan Johanna Jakobsdottir Kara L Hamilton-Nelson Sonia Moreno-Grau Robert Olaso Rachel Raybould Yuning Chen Amanda B Kuzma Mikko Hiltunen Taniesha Morgan Shahzad Ahmad Badri N Vardarajan Jacques Epelbaum Per Hoffmann Merce Boada Gary W Beecham Jean-Guillaume Garnier Denise Harold Annette L Fitzpatrick Otto Valladares Marie-Laure Moutet Amy Gerrish Albert V Smith Liming Qu Delphine Bacq Nicola Denning Xueqiu Jian Yi Zhao Maria Del Zompo Nick C Fox Seung-Hoan Choi Ignacio Mateo Joseph T Hughes Hieab H Adams John Malamon Florentino Sanchez-Garcia Yogen Patel Jennifer A Brody Beth A Dombroski Maria Candida Deniz Naranjo Makrina Daniilidou Gudny Eiriksdottir Shubhabrata Mukherjee David Wallon James Uphill Thor Aspelund Laura B Cantwell Fabienne Garzia Daniela Galimberti Edith Hofer Mariusz Butkiewicz Bertrand Fin Elio Scarpini Chloe Sarnowski Will S Bush Stéphane Meslage Johannes Kornhuber Charles C White Yuenjoo Song Robert C Barber Sebastiaan Engelborghs Sabrina Sordon Dina Voijnovic Perrie M Adams Rik Vandenberghe Manuel Mayhaus L Adrienne Cupples Marilyn S Albert Peter P De Deyn Wei Gu Jayanadra J Himali Duane Beekly Alessio Squassina Annette M Hartmann Adelina Orellana Deborah Blacker Eloy Rodriguez-Rodriguez Simon Lovestone Melissa E Garcia Rachelle S Doody Carmen Munoz-Fernadez Rebecca Sussams Honghuang Lin Thomas J Fairchild Yolanda A Benito Clive Holmes Hata Karamujić-Čomić Matthew P Frosch Hakan Thonberg Wolfgang Maier Gennady Roshchupkin Bernardino Ghetti Vilmantas Giedraitis Amit Kawalia Shuo Li Ryan M Huebinger Lena Kilander Susanne Moebus Isabel Hernández M Ilyas Kamboh RoseMarie Brundin James Turton Qiong Yang Mindy J Katz Letizia Concari Jenny Lord Alexa S Beiser C Dirk Keene Seppo Helisalmi Iwona Kloszewska Walter A Kukull Anne Maria Koivisto Aoibhinn Lynch Lluís Tarraga Eric B Larson Annakaisa Haapasalo Brian Lawlor Thomas H Mosley Richard B Lipton Vincenzo Solfrizzi Michael Gill W T Longstreth Thomas J Montine Vincenza Frisardi Monica Diez-Fairen Fernando Rivadeneira Ronald C Petersen Vincent Deramecourt Ignacio Alvarez Francesca Salani Antonio Ciaramella Eric Boerwinkle Eric M Reiman Nathalie Fievet Jerome I Rotter Joan S Reisch Olivier Hanon Chiara Cupidi A G Andre Uitterlinden Donald R Royall Carole Dufouil Raffaele Giovanni Maletta Itziar de Rojas Mary Sano Alexis Brice Roberta Cecchetti Peter St George-Hyslop Karen Ritchie Magda Tsolaki Debby W Tsuang Bruno Dubois David Craig Chuang-Kuo Wu Hilkka Soininen Despoina Avramidou Roger L Albin Laura Fratiglioni Antonia Germanou Liana G Apostolova Lina Keller Maria Koutroumani Steven E Arnold Francesco Panza Olymbia Gkatzima Sanjay Asthana Didier Hannequin Patrice Whitehead Craig S Atwood Paolo Caffarra Harald Hampel Inés Quintela Ángel Carracedo Lars Lannfelt David C Rubinsztein Lisa L Barnes Florence Pasquier Lutz Frölich Sandra Barral Bernadette McGuinness Thomas G Beach Janet A Johnston James T Becker Peter Passmore Eileen H Bigio Jonathan M Schott Thomas D Bird Jason D Warren Bradley F Boeve Michelle K Lupton James D Bowen Petra Proitsi Adam Boxer John F Powell James R Burke John S K Kauwe Jeffrey M Burns Michelangelo Mancuso Joseph D Buxbaum Ubaldo Bonuccelli Nigel J Cairns Andrew McQuillin Chuanhai Cao Gill Livingston Chris S Carlson Nicholas J Bass Cynthia M Carlsson John Hardy Regina M Carney Jose Bras Minerva M Carrasquillo Rita Guerreiro Mariet Allen Helena C Chui Elizabeth Fisher Carlo Masullo Elizabeth A Crocco Charles DeCarli Gina Bisceglio Malcolm Dick Li Ma Ranjan Duara Neill R Graff-Radford Denis A Evans Angela Hodges Kelley M Faber Martin Scherer Kenneth B Fallon Matthias Riemenschneider David W Fardo Reinhard Heun Martin R Farlow Heike Kölsch Steven Ferris Markus Leber Tatiana M Foroud Isabella Heuser Douglas R Galasko Ina Giegling Marla Gearing Michael Hüll Daniel H Geschwind John R Gilbert John Morris Robert C Green Kevin Mayo John H Growdon Thomas Feulner Ronald L Hamilton Lindy E Harrell Dmitriy Drichel Lawrence S Honig Thomas D Cushion Matthew J Huentelman Paul Hollingworth Christine M Hulette Bradley T Hyman Rachel Marshall Gail P Jarvik Alun Meggy Erin Abner Georgina E Menzies Lee-Way Jin Ganna Leonenko Luis M Real Gyungah R Jun Clinton T Baldwin Detelina Grozeva Anna Karydas Giancarlo Russo Jeffrey A Kaye Ronald Kim Frank Jessen Neil W Kowall Bruno Vellas Joel H Kramer Emma Vardy Frank M LaFerla Karl-Heinz Jöckel James J Lah Martin Dichgans James B Leverenz David Mann Allan I Levey Stuart Pickering-Brown Andrew P Lieberman Norman Klopp Kathryn L Lunetta H-Erich Wichmann Constantine G Lyketsos Kevin Morgan Daniel C Marson Kristelle Brown Frank Martiniuk Christopher Medway Deborah C Mash Markus M Nöthen Eliezer Masliah Nigel M Hooper Wayne C McCormick Antonio Daniele Susan M McCurry Anthony Bayer Andrew N McDavid John Gallacher Ann C McKee Hendrik van den Bussche Marsel Mesulam Carol Brayne Bruce L Miller Steffi Riedel-Heller Carol A Miller Joshua W Miller Ammar Al-Chalabi John C Morris Christopher E Shaw Amanda J Myers Jens Wiltfang Sid O'Bryant John M Olichney Victoria Alvarez Joseph E Parisi Andrew B Singleton Henry L Paulson John Collinge William R Perry Simon Mead Elaine Peskind David H Cribbs Martin Rossor Aimee Pierce Natalie S Ryan Wayne W Poon Benedetta Nacmias Huntington Potter Sandro Sorbi Joseph F Quinn Eleonora Sacchinelli Ashok Raj Gianfranco Spalletta Murray Raskind Carlo Caltagirone Paola Bossù Maria Donata Orfei Barry Reisberg Robert Clarke Christiane Reitz A David Smith John M Ringman Donald Warden Erik D Roberson Gordon Wilcock Ekaterina Rogaeva Amalia Cecilia Bruni Howard J Rosen Maura Gallo Roger N Rosenberg Yoav Ben-Shlomo Mark A Sager Patrizia Mecocci Andrew J Saykin Pau Pastor Michael L Cuccaro Jeffery M Vance Julie A Schneider Lori S Schneider Susan Slifer William W Seeley Amanda G Smith Joshua A Sonnen Salvatore Spina Robert A Stern Russell H Swerdlow Mitchell Tang Rudolph E Tanzi John Q Trojanowski Juan C Troncoso Vivianna M Van Deerlin Linda J Van Eldik Harry V Vinters Jean Paul Vonsattel Sandra Weintraub Kathleen A Welsh-Bohmer Kirk C Wilhelmsen Jennifer Williamson Thomas S Wingo Randall L Woltjer Clinton B Wright Chang-En Yu Lei Yu Yasaman Saba Alberto Pilotto Maria J Bullido Oliver Peters Paul K Crane David Bennett Paola Bosco Eliecer Coto Virginia Boccardi Phil L De Jager Alberto Lleo Nick Warner Oscar L Lopez Martin Ingelsson Panagiotis Deloukas Carlos Cruchaga Caroline Graff Rhian Gwilliam Myriam Fornage Alison M Goate Pascual Sanchez-Juan Patrick G Kehoe Najaf Amin Nilifur Ertekin-Taner Claudine Berr Stéphanie Debette Seth Love Lenore J Launer Steven G Younkin Jean-Francois Dartigues Chris Corcoran M Arfan Ikram Dennis W Dickson Gael Nicolas Dominique Campion JoAnn Tschanz Helena Schmidt Hakon Hakonarson Jordi Clarimon Ron Munger Reinhold Schmidt Lindsay A Farrer Christine Van Broeckhoven Michael C O'Donovan Anita L DeStefano Lesley Jones Jonathan L Haines Jean-Francois Deleuze Michael J Owen Vilmundur Gudnason Richard Mayeux Valentina Escott-Price Bruce M Psaty Alfredo Ramirez Li-San Wang Agustin Ruiz Cornelia M van Duijn Peter A Holmans Sudha Seshadri Julie Williams Phillippe Amouyel Gerard D Schellenberg Jean-Charles Lambert Margaret A Pericak-Vance

Nat Genet 2019 03 28;51(3):414-430. Epub 2019 Feb 28.

John P. Hussman Institute for Human Genomics, University of Miami Miller School of Medicine, Miami, FL, USA.

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http://dx.doi.org/10.1038/s41588-019-0358-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6463297PMC
March 2019

Cerebral tract integrity relates to white matter hyperintensities, cortex volume, and cognition.

Neurobiol Aging 2018 12 9;72:14-22. Epub 2018 Aug 9.

Department of Neurology, Center for Neurosciences, University of California at Davis, Davis, CA, USA; Imaging of Dementia and Aging (IDeA) Laboratory, University of California at Davis, Davis, CA, USA.

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http://dx.doi.org/10.1016/j.neurobiolaging.2018.08.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6242702PMC
December 2018

Circulating cortisol and cognitive and structural brain measures: The Framingham Heart Study.

Neurology 2018 11 24;91(21):e1961-e1970. Epub 2018 Oct 24.

From the Division of Endocrinology, Diabetes and Hypertension (J.B.E.-T.), Brigham and Women's Hospital/Harvard Medical School, Boston; National Heart, Lung, and Blood Institute (J.B.E.-T., S.C.C., J.J.H., A.S.B., R.S.V., S.S.), Framingham Heart Study, MA; Department of Neurology (S.C.C., J.J.H., A.S.B., S.S.) and Sections of Preventive Medicine and Epidemiology (R.S.V.) and Cardiology (R.S.V.), Department of Medicine, Boston University School of Medicine; Departments of Biostatistics (J.J.H., A.S.B.) and Epidemiology (R.S.V.), Boston University School of Public Health, MA; Department of Neurology (P.M., C.S.D.), University of California, Davis, Sacramento; and Glenn Biggs Institute of Alzheimer's and Neurodegenerative Diseases (S.S.), University of Texas Health Sciences Center, San Antonio.

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http://dx.doi.org/10.1212/WNL.0000000000006549DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6260201PMC
November 2018

Vascular risk at younger ages most strongly associates with current and future brain volume.

Neurology 2018 10 19;91(16):e1479-e1486. Epub 2018 Sep 19.

From the Melbourne Dementia Research Centre (M.P.P.), the Florey Institute for Neuroscience and Mental Health, the University of Melbourne, Australia; Department of Neurology (M.P.P., J.J.H., C.L.S., H.A., S.S., A.S.B), Boston University School of Medicine; Framingham Heart Study (M.P.P., K.D-.P., J.J.H., H.A., S.S., A.S.B., C.D.), MA; Centre for Human Psychopharmacology (M.P.P.), Swinburne University of Technology, Australia; Department of Biostatistics (K.D.-P., J.J.H., A.S.B.), Boston University School of Public Health, MA; Glenn Biggs Institute for Alzheimer's and Neurodegenerative Diseases (C.L.S., S.S., C.D.), University of Texas Health Sciences Center, San Antonio; and Department of Neurology, School of Medicine & Imaging of Dementia and Aging Laboratory, Center for Neuroscience, University of California Davis, Sacramento.

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http://dx.doi.org/10.1212/WNL.0000000000006360DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6202941PMC
October 2018

Genome-wide association study of 23,500 individuals identifies 7 loci associated with brain ventricular volume.

Nat Commun 2018 09 26;9(1):3945. Epub 2018 Sep 26.

The University of Texas Health Science Center at Houston Institute of Molecular Medicine, Houston, TX 77030, USA.

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http://dx.doi.org/10.1038/s41467-018-06234-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6158214PMC
September 2018

Exome Chip Analysis Identifies Low-Frequency and Rare Variants in MRPL38 for White Matter Hyperintensities on Brain Magnetic Resonance Imaging.

Stroke 2018 08;49(8):1812-1819

From the Institute of Molecular Medicine, McGovern Medical School at The University of Texas Health Science Center at Houston (M.F., X.J.).

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http://dx.doi.org/10.1161/STROKEAHA.118.020689DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6202149PMC
August 2018

Vascular risk factor burden and new-onset depression in the community.

Prev Med 2018 06 29;111:348-350. Epub 2017 Nov 29.

Department of Neurology, Boston University School of Medicine, 72 East Concord St., Boston, MA 02118, USA; Framingham Heart Study, 73 Mt. Wayte Avenue, Suite 2, Framingham, MA 01702-5827, USA; Centre for Human Psychopharmacology, Swinburne University of Technology, Burwood Rd, Hawthorn 3122, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.ypmed.2017.11.022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5930122PMC
June 2018

Analysis of shared heritability in common disorders of the brain.

Authors:
Verneri Anttila Brendan Bulik-Sullivan Hilary K Finucane Raymond K Walters Jose Bras Laramie Duncan Valentina Escott-Price Guido J Falcone Padhraig Gormley Rainer Malik Nikolaos A Patsopoulos Stephan Ripke Zhi Wei Dongmei Yu Phil H Lee Patrick Turley Benjamin Grenier-Boley Vincent Chouraki Yoichiro Kamatani Claudine Berr Luc Letenneur Didier Hannequin Philippe Amouyel Anne Boland Jean-François Deleuze Emmanuelle Duron Badri N Vardarajan Christiane Reitz Alison M Goate Matthew J Huentelman M Ilyas Kamboh Eric B Larson Ekaterina Rogaeva Peter St George-Hyslop Hakon Hakonarson Walter A Kukull Lindsay A Farrer Lisa L Barnes Thomas G Beach F Yesim Demirci Elizabeth Head Christine M Hulette Gregory A Jicha John S K Kauwe Jeffrey A Kaye James B Leverenz Allan I Levey Andrew P Lieberman Vernon S Pankratz Wayne W Poon Joseph F Quinn Andrew J Saykin Lon S Schneider Amanda G Smith Joshua A Sonnen Robert A Stern Vivianna M Van Deerlin Linda J Van Eldik Denise Harold Giancarlo Russo David C Rubinsztein Anthony Bayer Magda Tsolaki Petra Proitsi Nick C Fox Harald Hampel Michael J Owen Simon Mead Peter Passmore Kevin Morgan Markus M Nöthen Martin Rossor Michelle K Lupton Per Hoffmann Johannes Kornhuber Brian Lawlor Andrew McQuillin Ammar Al-Chalabi Joshua C Bis Agustin Ruiz Mercè Boada Sudha Seshadri Alexa Beiser Kenneth Rice Sven J van der Lee Philip L De Jager Daniel H Geschwind Matthias Riemenschneider Steffi Riedel-Heller Jerome I Rotter Gerhard Ransmayr Bradley T Hyman Carlos Cruchaga Montserrat Alegret Bendik Winsvold Priit Palta Kai-How Farh Ester Cuenca-Leon Nicholas Furlotte Tobias Kurth Lannie Ligthart Gisela M Terwindt Tobias Freilinger Caroline Ran Scott D Gordon Guntram Borck Hieab H H Adams Terho Lehtimäki Juho Wedenoja Julie E Buring Markus Schürks Maria Hrafnsdottir Jouke-Jan Hottenga Brenda Penninx Ville Artto Mari Kaunisto Salli Vepsäläinen Nicholas G Martin Grant W Montgomery Mitja I Kurki Eija Hämäläinen Hailiang Huang Jie Huang Cynthia Sandor Caleb Webber Bertram Muller-Myhsok Stefan Schreiber Veikko Salomaa Elizabeth Loehrer Hartmut Göbel Alfons Macaya Patricia Pozo-Rosich Thomas Hansen Thomas Werge Jaakko Kaprio Andres Metspalu Christian Kubisch Michel D Ferrari Andrea C Belin Arn M J M van den Maagdenberg John-Anker Zwart Dorret Boomsma Nicholas Eriksson Jes Olesen Daniel I Chasman Dale R Nyholt Andreja Avbersek Larry Baum Samuel Berkovic Jonathan Bradfield Russell J Buono Claudia B Catarino Patrick Cossette Peter De Jonghe Chantal Depondt Dennis Dlugos Thomas N Ferraro Jacqueline French Helle Hjalgrim Jennifer Jamnadas-Khoda Reetta Kälviäinen Wolfram S Kunz Holger Lerche Costin Leu Dick Lindhout Warren Lo Daniel Lowenstein Mark McCormack Rikke S Møller Anne Molloy Ping-Wing Ng Karen Oliver Michael Privitera Rodney Radtke Ann-Kathrin Ruppert Thomas Sander Steven Schachter Christoph Schankin Ingrid Scheffer Susanne Schoch Sanjay M Sisodiya Philip Smith Michael Sperling Pasquale Striano Rainer Surges G Neil Thomas Frank Visscher Christopher D Whelan Federico Zara Erin L Heinzen Anthony Marson Felicitas Becker Hans Stroink Fritz Zimprich Thomas Gasser Raphael Gibbs Peter Heutink Maria Martinez Huw R Morris Manu Sharma Mina Ryten Kin Y Mok Sara Pulit Steve Bevan Elizabeth Holliday John Attia Thomas Battey Giorgio Boncoraglio Vincent Thijs Wei-Min Chen Braxton Mitchell Peter Rothwell Pankaj Sharma Cathie Sudlow Astrid Vicente Hugh Markus Christina Kourkoulis Joana Pera Miriam Raffeld Scott Silliman Vesna Boraska Perica Laura M Thornton Laura M Huckins N William Rayner Cathryn M Lewis Monica Gratacos Filip Rybakowski Anna Keski-Rahkonen Anu Raevuori James I Hudson Ted Reichborn-Kjennerud Palmiero Monteleone Andreas Karwautz Katrin Mannik Jessica H Baker Julie K O'Toole Sara E Trace Oliver S P Davis Sietske G Helder Stefan Ehrlich Beate Herpertz-Dahlmann Unna N Danner Annemarie A van Elburg Maurizio Clementi Monica Forzan Elisa Docampo Jolanta Lissowska Joanna Hauser Alfonso Tortorella Mario Maj Fragiskos Gonidakis Konstantinos Tziouvas Hana Papezova Zeynep Yilmaz Gudrun Wagner Sarah Cohen-Woods Stefan Herms Antonio Julià Raquel Rabionet Danielle M Dick Samuli Ripatti Ole A Andreassen Thomas Espeseth Astri J Lundervold Vidar M Steen Dalila Pinto Stephen W Scherer Harald Aschauer Alexandra Schosser Lars Alfredsson Leonid Padyukov Katherine A Halmi James Mitchell Michael Strober Andrew W Bergen Walter Kaye Jin Peng Szatkiewicz Bru Cormand Josep Antoni Ramos-Quiroga Cristina Sánchez-Mora Marta Ribasés Miguel Casas Amaia Hervas Maria Jesús Arranz Jan Haavik Tetyana Zayats Stefan Johansson Nigel Williams Astrid Dempfle Aribert Rothenberger Jonna Kuntsi Robert D Oades Tobias Banaschewski Barbara Franke Jan K Buitelaar Alejandro Arias Vasquez Alysa E Doyle Andreas Reif Klaus-Peter Lesch Christine Freitag Olga Rivero Haukur Palmason Marcel Romanos Kate Langley Marcella Rietschel Stephanie H Witt Soeren Dalsgaard Anders D Børglum Irwin Waldman Beth Wilmot Nikolas Molly Claiton H D Bau Jennifer Crosbie Russell Schachar Sandra K Loo James J McGough Eugenio H Grevet Sarah E Medland Elise Robinson Lauren A Weiss Elena Bacchelli Anthony Bailey Vanessa Bal Agatino Battaglia Catalina Betancur Patrick Bolton Rita Cantor Patrícia Celestino-Soper Geraldine Dawson Silvia De Rubeis Frederico Duque Andrew Green Sabine M Klauck Marion Leboyer Pat Levitt Elena Maestrini Shrikant Mane Daniel Moreno- De-Luca Jeremy Parr Regina Regan Abraham Reichenberg Sven Sandin Jacob Vorstman Thomas Wassink Ellen Wijsman Edwin Cook Susan Santangelo Richard Delorme Bernadette Rogé Tiago Magalhaes Dan Arking Thomas G Schulze Robert C Thompson Jana Strohmaier Keith Matthews Ingrid Melle Derek Morris Douglas Blackwood Andrew McIntosh Sarah E Bergen Martin Schalling Stéphane Jamain Anna Maaser Sascha B Fischer Céline S Reinbold Janice M Fullerton José Guzman-Parra Fermin Mayoral Peter R Schofield Sven Cichon Thomas W Mühleisen Franziska Degenhardt Johannes Schumacher Michael Bauer Philip B Mitchell Elliot S Gershon John Rice James B Potash Peter P Zandi Nick Craddock I Nicol Ferrier Martin Alda Guy A Rouleau Gustavo Turecki Roel Ophoff Carlos Pato Adebayo Anjorin Eli Stahl Markus Leber Piotr M Czerski Cristiana Cruceanu Ian R Jones Danielle Posthuma Till F M Andlauer Andreas J Forstner Fabian Streit Bernhard T Baune Tracy Air Grant Sinnamon Naomi R Wray Donald J MacIntyre David Porteous Georg Homuth Margarita Rivera Jakob Grove Christel M Middeldorp Ian Hickie Michele Pergadia Divya Mehta Johannes H Smit Rick Jansen Eco de Geus Erin Dunn Qingqin S Li Matthias Nauck Robert A Schoevers Aartjan Tf Beekman James A Knowles Alexander Viktorin Paul Arnold Cathy L Barr Gabriel Bedoya-Berrio O Joseph Bienvenu Helena Brentani Christie Burton Beatriz Camarena Carolina Cappi Danielle Cath Maria Cavallini Daniele Cusi Sabrina Darrow Damiaan Denys Eske M Derks Andrea Dietrich Thomas Fernandez Martijn Figee Nelson Freimer Gloria Gerber Marco Grados Erica Greenberg Gregory L Hanna Andreas Hartmann Matthew E Hirschtritt Pieter J Hoekstra Alden Huang Chaim Huyser Cornelia Illmann Michael Jenike Samuel Kuperman Bennett Leventhal Christine Lochner Gholson J Lyon Fabio Macciardi Marcos Madruga-Garrido Irene A Malaty Athanasios Maras Lauren McGrath Eurípedes C Miguel Pablo Mir Gerald Nestadt Humberto Nicolini Michael S Okun Andrew Pakstis Peristera Paschou John Piacentini Christopher Pittenger Kerstin Plessen Vasily Ramensky Eliana M Ramos Victor Reus Margaret A Richter Mark A Riddle Mary M Robertson Veit Roessner Maria Rosário Jack F Samuels Paul Sandor Dan J Stein Fotis Tsetsos Filip Van Nieuwerburgh Sarah Weatherall Jens R Wendland Tomasz Wolanczyk Yulia Worbe Gwyneth Zai Fernando S Goes Nicole McLaughlin Paul S Nestadt Hans-Jorgen Grabe Christel Depienne Anuar Konkashbaev Nuria Lanzagorta Ana Valencia-Duarte Elvira Bramon Nancy Buccola Wiepke Cahn Murray Cairns Siow A Chong David Cohen Benedicto Crespo-Facorro James Crowley Michael Davidson Lynn DeLisi Timothy Dinan Gary Donohoe Elodie Drapeau Jubao Duan Lieuwe Haan David Hougaard Sena Karachanak-Yankova Andrey Khrunin Janis Klovins Vaidutis Kučinskas Jimmy Lee Chee Keong Svetlana Limborska Carmel Loughland Jouko Lönnqvist Brion Maher Manuel Mattheisen Colm McDonald Kieran C Murphy Igor Nenadic Jim van Os Christos Pantelis Michele Pato Tracey Petryshen Digby Quested Panos Roussos Alan R Sanders Ulrich Schall Sibylle G Schwab Kang Sim Hon-Cheong So Elisabeth Stögmann Mythily Subramaniam Draga Toncheva John Waddington James Walters Mark Weiser Wei Cheng Robert Cloninger David Curtis Pablo V Gejman Frans Henskens Morten Mattingsdal Sang-Yun Oh Rodney Scott Bradley Webb Gerome Breen Claire Churchhouse Cynthia M Bulik Mark Daly Martin Dichgans Stephen V Faraone Rita Guerreiro Peter Holmans Kenneth S Kendler Bobby Koeleman Carol A Mathews Alkes Price Jeremiah Scharf Pamela Sklar Julie Williams Nicholas W Wood Chris Cotsapas Aarno Palotie Jordan W Smoller Patrick Sullivan Jonathan Rosand Aiden Corvin Benjamin M Neale Jonathan M Schott Richard Anney Josephine Elia Maria Grigoroiu-Serbanescu Howard J Edenberg Robin Murray

Science 2018 06;360(6395)

Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.

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http://dx.doi.org/10.1126/science.aap8757DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6097237PMC
June 2018

Are Trends in Dementia Incidence Associated With Compression in Morbidity? Evidence From The Framingham Heart Study.

J Gerontol B Psychol Sci Soc Sci 2018 04;73(suppl_1):S65-S72

Boston University Schools of Public Health and Medicine and the Framingham Heart Study, Massachusetts.

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http://dx.doi.org/10.1093/geronb/gby001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6019043PMC
April 2018

Atrial fibrillation and cognitive decline in the Framingham Heart Study.

Heart Rhythm 2018 02 22;15(2):166-172. Epub 2017 Sep 22.

Department of Neurology, Boston University School of Medicine, Boston, Massachusetts; The Framingham Heart Study, Framingham, Massachusetts; Department of Anatomy & Neurobiology, Boston University School of Public Health, Boston, Massachusetts; Department of Epidemiology, Boston University School of Public Health, Boston, Massachusetts. Electronic address:

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http://dx.doi.org/10.1016/j.hrthm.2017.09.036DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5881912PMC
February 2018

Whole genome sequence analyses of brain imaging measures in the Framingham Study.

Neurology 2018 01 27;90(3):e188-e196. Epub 2017 Dec 27.

From the Department of Epidemiology (C.S., L.A.C., A.S.B., A.L.D., J.D.), Boston University School of Public Health; Boston University and the NHLBI's Framingham Heart Study (C.L.S., A.N.P., L.A.C., R.S.V., A.S.B., A.L.D., J.D., S.S.); Departments of Neurology (C.L.S., A.S.B., A.L.D., S.S.) and Cardiology, Preventive Medicine & Epidemiology (R.S.V.), Boston University School of Medicine, Boston, MA; Department of Neurology and Center for Neuroscience (C.D.), University of California at Davis; Department of Physiology and Biophysics (J.G.W.), University of Mississippi Medical Center, Jackson; Cardiovascular Health Research Unit (J.C.B.), Department of Medicine, University of Washington, Seattle; and Institute of Molecular Medicine (M.F.), University of Texas Health Science Center, Houston.

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http://dx.doi.org/10.1212/WNL.0000000000004820DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5772158PMC
January 2018

Association of amine biomarkers with incident dementia and Alzheimer's disease in the Framingham Study.

Alzheimers Dement 2017 Dec 8;13(12):1327-1336. Epub 2017 Jun 8.

Department of Neurology, Boston University School of Medicine, Boston, MA, USA; The Framingham Heart Study, Framingham, MA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jalz.2017.04.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5722716PMC
December 2017

Blood pressure from mid- to late life and risk of incident dementia.

Neurology 2017 Dec 8;89(24):2447-2454. Epub 2017 Nov 8.

From the Department of Neurology (E.R.M.), Brigham & Women's Hospital; Department of Neurology (E.R.M., S.M.G.), Massachusetts General Hospital; Harvard Medical School (E.R.M., S.M.G.); Boston University School of Medicine (A.S.B., R.S.V., S.S.); Boston University School of Public Health (A.S.B., K.L.P., R.S.V.); Framingham Heart Study (A.S.B., R.S.V., S.S.), MA; and Department of Neurology (C.D.), University of California, Davis.

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http://dx.doi.org/10.1212/WNL.0000000000004741DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5729797PMC
December 2017

Pulse Pressure Is Associated With Early Brain Atrophy and Cognitive Decline: Modifying Effects of APOE-ε4.

Alzheimer Dis Assoc Disord 2016 Jul-Sep;30(3):210-5

*Department of Psychology, University of Southern California, Los Angeles∥Veterans Affairs San Diego Healthcare System¶Department of Psychiatry, University of California, San Diego, La Jolla, CA†The Framingham Heart Study, FraminghamDepartments of ‡Biostatistics§Department of Neurology, Boston University School of Medicine, Boston, MA#Department of Psychiatry, University of Illinois at Chicago, Chicago, IL**Drexel Neuroscience Institute, College of Medicine, Drexel University, Philadelphia, PA.

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http://dx.doi.org/10.1097/WAD.0000000000000127DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4999260PMC
November 2017

Association of descending thoracic aortic plaque with brain atrophy and white matter hyperintensities: The Framingham Heart Study.

Atherosclerosis 2017 10 23;265:305-311. Epub 2017 Jun 23.

Department of Neurology, Boston University School of Medicine, 72 East Concord Street, C-3, Boston, MA 02118, USA; National Heart, Lung, and Blood Institute's Framingham Study, 73 Mt. Wayte Avenue, Suite 2, Framingham, MA 01702, USA.

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http://dx.doi.org/10.1016/j.atherosclerosis.2017.06.919DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5617776PMC
October 2017

Sugary beverage intake and preclinical Alzheimer's disease in the community.

Alzheimers Dement 2017 Sep 6;13(9):955-964. Epub 2017 Mar 6.

Department of Neurology, Boston University School of Medicine, Boston, MA, USA; Framingham Heart Study, Framingham, MA, USA.

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http://dx.doi.org/10.1016/j.jalz.2017.01.024DOI Listing
September 2017

Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease.

Authors:
Rebecca Sims Sven J van der Lee Adam C Naj Céline Bellenguez Nandini Badarinarayan Johanna Jakobsdottir Brian W Kunkle Anne Boland Rachel Raybould Joshua C Bis Eden R Martin Benjamin Grenier-Boley Stefanie Heilmann-Heimbach Vincent Chouraki Amanda B Kuzma Kristel Sleegers Maria Vronskaya Agustin Ruiz Robert R Graham Robert Olaso Per Hoffmann Megan L Grove Badri N Vardarajan Mikko Hiltunen Markus M Nöthen Charles C White Kara L Hamilton-Nelson Jacques Epelbaum Wolfgang Maier Seung-Hoan Choi Gary W Beecham Cécile Dulary Stefan Herms Albert V Smith Cory C Funk Céline Derbois Andreas J Forstner Shahzad Ahmad Hongdong Li Delphine Bacq Denise Harold Claudia L Satizabal Otto Valladares Alessio Squassina Rhodri Thomas Jennifer A Brody Liming Qu Pascual Sánchez-Juan Taniesha Morgan Frank J Wolters Yi Zhao Florentino Sanchez Garcia Nicola Denning Myriam Fornage John Malamon Maria Candida Deniz Naranjo Elisa Majounie Thomas H Mosley Beth Dombroski David Wallon Michelle K Lupton Josée Dupuis Patrice Whitehead Laura Fratiglioni Christopher Medway Xueqiu Jian Shubhabrata Mukherjee Lina Keller Kristelle Brown Honghuang Lin Laura B Cantwell Francesco Panza Bernadette McGuinness Sonia Moreno-Grau Jeremy D Burgess Vincenzo Solfrizzi Petra Proitsi Hieab H Adams Mariet Allen Davide Seripa Pau Pastor L Adrienne Cupples Nathan D Price Didier Hannequin Ana Frank-García Daniel Levy Paramita Chakrabarty Paolo Caffarra Ina Giegling Alexa S Beiser Vilmantas Giedraitis Harald Hampel Melissa E Garcia Xue Wang Lars Lannfelt Patrizia Mecocci Gudny Eiriksdottir Paul K Crane Florence Pasquier Virginia Boccardi Isabel Henández Robert C Barber Martin Scherer Lluis Tarraga Perrie M Adams Markus Leber Yuning Chen Marilyn S Albert Steffi Riedel-Heller Valur Emilsson Duane Beekly Anne Braae Reinhold Schmidt Deborah Blacker Carlo Masullo Helena Schmidt Rachelle S Doody Gianfranco Spalletta W T Longstreth Thomas J Fairchild Paola Bossù Oscar L Lopez Matthew P Frosch Eleonora Sacchinelli Bernardino Ghetti Qiong Yang Ryan M Huebinger Frank Jessen Shuo Li M Ilyas Kamboh John Morris Oscar Sotolongo-Grau Mindy J Katz Chris Corcoran Melanie Dunstan Amy Braddel Charlene Thomas Alun Meggy Rachel Marshall Amy Gerrish Jade Chapman Miquel Aguilar Sarah Taylor Matt Hill Mònica Díez Fairén Angela Hodges Bruno Vellas Hilkka Soininen Iwona Kloszewska Makrina Daniilidou James Uphill Yogen Patel Joseph T Hughes Jenny Lord James Turton Annette M Hartmann Roberta Cecchetti Chiara Fenoglio Maria Serpente Marina Arcaro Carlo Caltagirone Maria Donata Orfei Antonio Ciaramella Sabrina Pichler Manuel Mayhaus Wei Gu Alberto Lleó Juan Fortea Rafael Blesa Imelda S Barber Keeley Brookes Chiara Cupidi Raffaele Giovanni Maletta David Carrell Sandro Sorbi Susanne Moebus Maria Urbano Alberto Pilotto Johannes Kornhuber Paolo Bosco Stephen Todd David Craig Janet Johnston Michael Gill Brian Lawlor Aoibhinn Lynch Nick C Fox John Hardy Roger L Albin Liana G Apostolova Steven E Arnold Sanjay Asthana Craig S Atwood Clinton T Baldwin Lisa L Barnes Sandra Barral Thomas G Beach James T Becker Eileen H Bigio Thomas D Bird Bradley F Boeve James D Bowen Adam Boxer James R Burke Jeffrey M Burns Joseph D Buxbaum Nigel J Cairns Chuanhai Cao Chris S Carlson Cynthia M Carlsson Regina M Carney Minerva M Carrasquillo Steven L Carroll Carolina Ceballos Diaz Helena C Chui David G Clark David H Cribbs Elizabeth A Crocco Charles DeCarli Malcolm Dick Ranjan Duara Denis A Evans Kelley M Faber Kenneth B Fallon David W Fardo Martin R Farlow Steven Ferris Tatiana M Foroud Douglas R Galasko Marla Gearing Daniel H Geschwind John R Gilbert Neill R Graff-Radford Robert C Green John H Growdon Ronald L Hamilton Lindy E Harrell Lawrence S Honig Matthew J Huentelman Christine M Hulette Bradley T Hyman Gail P Jarvik Erin Abner Lee-Way Jin Gyungah Jun Anna Karydas Jeffrey A Kaye Ronald Kim Neil W Kowall Joel H Kramer Frank M LaFerla James J Lah James B Leverenz Allan I Levey Ge Li Andrew P Lieberman Kathryn L Lunetta Constantine G Lyketsos Daniel C Marson Frank Martiniuk Deborah C Mash Eliezer Masliah Wayne C McCormick Susan M McCurry Andrew N McDavid Ann C McKee Marsel Mesulam Bruce L Miller Carol A Miller Joshua W Miller John C Morris Jill R Murrell Amanda J Myers Sid O'Bryant John M Olichney Vernon S Pankratz Joseph E Parisi Henry L Paulson William Perry Elaine Peskind Aimee Pierce Wayne W Poon Huntington Potter Joseph F Quinn Ashok Raj Murray Raskind Barry Reisberg Christiane Reitz John M Ringman Erik D Roberson Ekaterina Rogaeva Howard J Rosen Roger N Rosenberg Mark A Sager Andrew J Saykin Julie A Schneider Lon S Schneider William W Seeley Amanda G Smith Joshua A Sonnen Salvatore Spina Robert A Stern Russell H Swerdlow Rudolph E Tanzi Tricia A Thornton-Wells John Q Trojanowski Juan C Troncoso Vivianna M Van Deerlin Linda J Van Eldik Harry V Vinters Jean Paul Vonsattel Sandra Weintraub Kathleen A Welsh-Bohmer Kirk C Wilhelmsen Jennifer Williamson Thomas S Wingo Randall L Woltjer Clinton B Wright Chang-En Yu Lei Yu Fabienne Garzia Feroze Golamaully Gislain Septier Sebastien Engelborghs Rik Vandenberghe Peter P De Deyn Carmen Muñoz Fernadez Yoland Aladro Benito Hakan Thonberg Charlotte Forsell Lena Lilius Anne Kinhult-Stählbom Lena Kilander RoseMarie Brundin Letizia Concari Seppo Helisalmi Anne Maria Koivisto Annakaisa Haapasalo Vincent Dermecourt Nathalie Fievet Olivier Hanon Carole Dufouil Alexis Brice Karen Ritchie Bruno Dubois Jayanadra J Himali C Dirk Keene JoAnn Tschanz Annette L Fitzpatrick Walter A Kukull Maria Norton Thor Aspelund Eric B Larson Ron Munger Jerome I Rotter Richard B Lipton María J Bullido Albert Hofman Thomas J Montine Eliecer Coto Eric Boerwinkle Ronald C Petersen Victoria Alvarez Fernando Rivadeneira Eric M Reiman Maura Gallo Christopher J O'Donnell Joan S Reisch Amalia Cecilia Bruni Donald R Royall Martin Dichgans Mary Sano Daniela Galimberti Peter St George-Hyslop Elio Scarpini Debby W Tsuang Michelangelo Mancuso Ubaldo Bonuccelli Ashley R Winslow Antonio Daniele Chuang-Kuo Wu Oliver Peters Benedetta Nacmias Matthias Riemenschneider Reinhard Heun Carol Brayne David C Rubinsztein Jose Bras Rita Guerreiro Ammar Al-Chalabi Christopher E Shaw John Collinge David Mann Magda Tsolaki Jordi Clarimón Rebecca Sussams Simon Lovestone Michael C O'Donovan Michael J Owen Timothy W Behrens Simon Mead Alison M Goate Andre G Uitterlinden Clive Holmes Carlos Cruchaga Martin Ingelsson David A Bennett John Powell Todd E Golde Caroline Graff Philip L De Jager Kevin Morgan Nilufer Ertekin-Taner Onofre Combarros Bruce M Psaty Peter Passmore Steven G Younkin Claudine Berr Vilmundur Gudnason Dan Rujescu Dennis W Dickson Jean-François Dartigues Anita L DeStefano Sara Ortega-Cubero Hakon Hakonarson Dominique Campion Merce Boada John Keoni Kauwe Lindsay A Farrer Christine Van Broeckhoven M Arfan Ikram Lesley Jones Jonathan L Haines Christophe Tzourio Lenore J Launer Valentina Escott-Price Richard Mayeux Jean-François Deleuze Najaf Amin Peter A Holmans Margaret A Pericak-Vance Philippe Amouyel Cornelia M van Duijn Alfredo Ramirez Li-San Wang Jean-Charles Lambert Sudha Seshadri Julie Williams Gerard D Schellenberg

Nat Genet 2017 09 17;49(9):1373-1384. Epub 2017 Jul 17.

Penn Neurodegeneration Genomics Center, Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA.

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http://dx.doi.org/10.1038/ng.3916DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5669039PMC
September 2017

Sleep architecture and the risk of incident dementia in the community.

Neurology 2017 Sep 23;89(12):1244-1250. Epub 2017 Aug 23.

From the Department of Neurology (M.P.P., J.J.H., A.S.B., C.L.S., H.J.A., S.H.A., S.S.), Boston University School of Medicine; Framingham Heart Study (M.P.P., J.J.H., A.S.B., C.L.S., H.J.A., S.H.A., S.S.), MA; Centre for Human Psychopharmacology (M.P.P.), Swinburne University of Technology, Australia; Department of Biostatistics (J.J.H., A.S.B.), Boston University School of Public Health; Cognitive Neurology Unit (N.A.G.) and Division of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine (R.J.T.), Beth Israel Deaconess Medical Center; Harvard Medical School (N.A.G., D.J.G.); Division of Sleep and Circadian Disorders (D.J.G.), Brigham & Women's Hospital, Boston; and Medical Service (D.J.G.), VA Boston Healthcare System, MA.

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http://dx.doi.org/10.1212/WNL.0000000000004373DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5606917PMC
September 2017

Whole blood gene expression and white matter Hyperintensities.

Mol Neurodegener 2017 09 18;12(1):67. Epub 2017 Sep 18.

National Heart Lung and Blood Institute's and Boston University's Framingham Heart Study, Framingham, MA, USA.

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http://dx.doi.org/10.1186/s13024-017-0209-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5604498PMC
September 2017

Serum Insulin-Like Growth Factor 1 and the Risk of Ischemic Stroke: The Framingham Study.

Stroke 2017 07 8;48(7):1760-1765. Epub 2017 Jun 8.

From the Framingham Heart Study, MA (H.S., J.J.H., A.S.B., J.R.R., C.S.K., R.S.V., S.S.); Boston University School of Public Health, MA (J.J.H., A.S.B.); McMaster University/Population Health Research Institute, Hamilton, Ontario, Canada (A.S.); Department of Neurology, University of Toronto, Ontario, Canada (A.P.); Department of Medicine, Tufts University School of Medicine, Boston, MA (R.R.); Department of Neurology, Boston University School of Medicine, MA (J.J.H., A.S.B., J.R.R., C.S.K., R.S.V., S.S.); and Department of Neurology, Wayne State University School of Medicine, Detroit, MI (H.S.).

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https://www.ahajournals.org/doi/10.1161/STROKEAHA.116.016563
Publisher Site
http://dx.doi.org/10.1161/STROKEAHA.116.016563DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5505338PMC
July 2017

Cerebral microbleeds and risk of incident dementia: the Framingham Heart Study.

Neurobiol Aging 2017 06 6;54:94-99. Epub 2017 Mar 6.

Department of Neurology, School of Public Health at Boston University, Boston, MA, USA; NHLBI's Framingham Heart Study, Framingham, MA, USA.

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http://dx.doi.org/10.1016/j.neurobiolaging.2017.02.018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5401784PMC
June 2017

Aortic Stiffness, Increased White Matter Free Water, and Altered Microstructural Integrity: A Continuum of Injury.

Stroke 2017 06 4;48(6):1567-1573. Epub 2017 May 4.

From the Imaging of Dementia and Aging (IDeA) Laboratory, Davis, CA (P.M., E.F., C.D.); Department of Neurology and Center for Neurosciences, University of California, Davis (P.M., E.F., C.D.); Cardiovascular Engineering, Inc, Norwood, MA (G.F.M.); The Framingham Heart Study, MA (J.J.H., A.B., M.P.P., C.L.S., S.S.); Department of Neurology (J.J.H., A.B., M.P.P., C.L.S., S.S.) and Department of Medicine (R.S.V.), Boston University School of Medicine, MA; Department of Biostatistics, Boston University School of Public Health, MA (J.J.H., A.B.); Cardiovascular Division, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA (C.W.T.); and Centre for Human Psychopharmacology, Swinburne University of Technology, Hawthorn, Australia (M.P.P.).

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http://dx.doi.org/10.1161/STROKEAHA.116.016321DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5502744PMC
June 2017

The changing prevalence and incidence of dementia over time - current evidence.

Nat Rev Neurol 2017 Jun 12;13(6):327-339. Epub 2017 May 12.

Department of Public Health and Primary Care, Cambridge Institute of Public Health, Forvie Site, University of Cambridge, School of Clinical Medicine, Cambridge Biomedical Campus, Cambridge CB2 0SR, UK.

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http://dx.doi.org/10.1038/nrneurol.2017.63DOI Listing
June 2017

Sugar- and Artificially Sweetened Beverages and the Risks of Incident Stroke and Dementia: A Prospective Cohort Study.

Stroke 2017 05;48(5):1139-1146

From the Department of Neurology (M.P.P., J.J.H., A.S.B., H.J.A., C.L.S., S.S.) and Sections of Preventive Medicine and Epidemiology, Department of Medicine (R.S.V), Boston University School of Medicine, MA; Framingham Heart Study, MA (M.P.P., J.J.H., A.S.B., H.J.A., C.L.S., R.S.V., S.S., P.F.J.); Centre for Human Psychopharmacology, Swinburne University of Technology, Australia (M.P.P.); Department of Biostatistics (J.J.H., A.S.B.) and Department of Epidemiology (R.S.V.), Boston University School of Public Health, MA; and Jean Mayer US Department of Agriculture Human Nutrition Research Center on Aging, Tufts University, Boston, MA (P.F.J.).

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http://dx.doi.org/10.1161/STROKEAHA.116.016027DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5405737PMC
May 2017

Cerebral Microbleeds as Predictors of Mortality: The Framingham Heart Study.

Stroke 2017 03 31;48(3):781-783. Epub 2017 Jan 31.

From the Department of Neurology (J.R.R., A.B., P.A.W., C.S.K., S.S.), Section of Preventive Medicine (V.S.R.), and Department of Cardiology (V.S.R.), School of Medicine and Department of Biostatistics (S.R.P., A.B., J.J.H.), School of Public Health at Boston University, MA; Department of Medicine-Neurology, McMaster University and Population Health Research Institute, Hamilton, Ontario, Canada (A.S.); Department of Neurology, University of California-Davis (C.D.); and the NHLBI's Framingham Heart Study, Framingham, MA (J.R.R., S.R.P., A.B., J.J.H., P.A.W., C.S.K., V.S.R., S.S.).

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http://dx.doi.org/10.1161/STROKEAHA.116.015354DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5330856PMC
March 2017

Revised Framingham Stroke Risk Profile to Reflect Temporal Trends.

Circulation 2017 Mar 3;135(12):1145-1159. Epub 2017 Feb 3.

From Inserm, Bordeaux Population Health Research Center, UMR 1219, Univ. Bordeaux, France (C.D., C.T., C.S., G.C.); ISPED, Univ. Bordeaux, France (C.D., C.S., G.C.); CHU de Bordeaux, Pole de sante publique, France (C.D., C.T., G.C.); Department of Neurology, School of Medicine (A.B., P.A.W., J.J.H., H.J.A., M.K.-H., C.S.K., A.P., J.R.R., S.S.), Department of Biostatistics, School of Public Health (A.B., L.S.), and Department of Mathematics (R.B.D.), Boston University, MA; National Heart, Lung, and Blood Institute's Framingham Heart Study, MA (A.B., P.A.W., A.J.W., J.J.H., H.J.A., M.K.-H., C.S.K., A.P., J.R.R., R.B.D., R.S.V., S.S.); Department of Biostatistics, Drexel University School of Public Health, Philadelphia, PA (L.A.M.); Departments of Epidemiology (V.J.H.) and Biostatistics (G.H.), School of Public Health, University of Alabama at Birmingham; and INSERM Unit 1061, Montpellier University, France (K.R.).

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http://dx.doi.org/10.1161/CIRCULATIONAHA.115.021275DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5504355PMC
March 2017

Prolonged sleep duration as a marker of early neurodegeneration predicting incident dementia.

Neurology 2017 Mar 22;88(12):1172-1179. Epub 2017 Feb 22.

From the Department of Neurology (A.J.W., A.B., J.J.H., S.H.A., M.P.P., S.S.), Boston University School of Medicine; Department of Biostatistics (A.B., J.J.H.), Boston University School of Public Health; Framingham Heart Study (A.B., J.J.H., S.H.A., M.P.P., S.S.); Department of Neuroscience (N.J.), Boston University, MA; University of California at Davis (C.D.), Sacramento; and Center for Human Psychopharmacology (M.P.P.), Swinburne University of Technology, Australia.

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http://dx.doi.org/10.1212/WNL.0000000000003732DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5373785PMC
March 2017

Effects of white matter integrity and brain volumes on late life depression in the Framingham Heart Study.

Int J Geriatr Psychiatry 2017 02 5;32(2):214-221. Epub 2016 Apr 5.

Department of Neurology, Boston University School of Medicine, Boston, MA, USA.

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http://dx.doi.org/10.1002/gps.4469DOI Listing
February 2017

Lacunar Infarcts and Intracerebral Hemorrhage Differences: A Nested Case-Control Analysis in the FHS (Framingham Heart Study).

Stroke 2017 02 22;48(2):486-489. Epub 2016 Dec 22.

From the Department of Neurology, Beth Israel Deaconess Medical Center, Boston, MA (V.-A.L.); Department of Biostatistics (A.B., J.H.) and Department of Neurology (A.B., J.H., H.A., J.R.R., S.S.), Boston University School of Medicine, MA; Department of Neurology, University of California Davis (C.D.); and Framingham Heart Study, MA (V.-A.L., A.B., J.H., H.A., J.R.R., S.S.).

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5288009PMC
February 2017

Serum brain-derived neurotrophic factor and risk of atrial fibrillation.

Am Heart J 2017 Jan 17;183:69-73. Epub 2016 Oct 17.

National Heart Lung and Blood Institute's and Boston University's Framingham Heart Study, Framingham, MA, USA.

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http://dx.doi.org/10.1016/j.ahj.2016.07.027DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5166602PMC
January 2017

Novel genetic loci associated with hippocampal volume.

Authors:
Derrek P Hibar Hieab H H Adams Neda Jahanshad Ganesh Chauhan Jason L Stein Edith Hofer Miguel E Renteria Joshua C Bis Alejandro Arias-Vasquez M Kamran Ikram Sylvane Desrivières Meike W Vernooij Lucija Abramovic Saud Alhusaini Najaf Amin Micael Andersson Konstantinos Arfanakis Benjamin S Aribisala Nicola J Armstrong Lavinia Athanasiu Tomas Axelsson Ashley H Beecham Alexa Beiser Manon Bernard Susan H Blanton Marc M Bohlken Marco P Boks Janita Bralten Adam M Brickman Owen Carmichael M Mallar Chakravarty Qiang Chen Christopher R K Ching Vincent Chouraki Gabriel Cuellar-Partida Fabrice Crivello Anouk Den Braber Nhat Trung Doan Stefan Ehrlich Sudheer Giddaluru Aaron L Goldman Rebecca F Gottesman Oliver Grimm Michael E Griswold Tulio Guadalupe Boris A Gutman Johanna Hass Unn K Haukvik David Hoehn Avram J Holmes Martine Hoogman Deborah Janowitz Tianye Jia Kjetil N Jørgensen Nazanin Karbalai Dalia Kasperaviciute Sungeun Kim Marieke Klein Bernd Kraemer Phil H Lee David C M Liewald Lorna M Lopez Michelle Luciano Christine Macare Andre F Marquand Mar Matarin Karen A Mather Manuel Mattheisen David R McKay Yuri Milaneschi Susana Muñoz Maniega Kwangsik Nho Allison C Nugent Paul Nyquist Loes M Olde Loohuis Jaap Oosterlaan Martina Papmeyer Lukas Pirpamer Benno Pütz Adaikalavan Ramasamy Jennifer S Richards Shannon L Risacher Roberto Roiz-Santiañez Nanda Rommelse Stefan Ropele Emma J Rose Natalie A Royle Tatjana Rundek Philipp G Sämann Arvin Saremi Claudia L Satizabal Lianne Schmaal Andrew J Schork Li Shen Jean Shin Elena Shumskaya Albert V Smith Emma Sprooten Lachlan T Strike Alexander Teumer Diana Tordesillas-Gutierrez Roberto Toro Daniah Trabzuni Stella Trompet Dhananjay Vaidya Jeroen Van der Grond Sven J Van der Lee Dennis Van der Meer Marjolein M J Van Donkelaar Kristel R Van Eijk Theo G M Van Erp Daan Van Rooij Esther Walton Lars T Westlye Christopher D Whelan Beverly G Windham Anderson M Winkler Katharina Wittfeld Girma Woldehawariat Christiane Wolf Thomas Wolfers Lisa R Yanek Jingyun Yang Alex Zijdenbos Marcel P Zwiers Ingrid Agartz Laura Almasy David Ames Philippe Amouyel Ole A Andreassen Sampath Arepalli Amelia A Assareh Sandra Barral Mark E Bastin Diane M Becker James T Becker David A Bennett John Blangero Hans van Bokhoven Dorret I Boomsma Henry Brodaty Rachel M Brouwer Han G Brunner Randy L Buckner Jan K Buitelaar Kazima B Bulayeva Wiepke Cahn Vince D Calhoun Dara M Cannon Gianpiero L Cavalleri Ching-Yu Cheng Sven Cichon Mark R Cookson Aiden Corvin Benedicto Crespo-Facorro Joanne E Curran Michael Czisch Anders M Dale Gareth E Davies Anton J M De Craen Eco J C De Geus Philip L De Jager Greig I De Zubicaray Ian J Deary Stéphanie Debette Charles DeCarli Norman Delanty Chantal Depondt Anita DeStefano Allissa Dillman Srdjan Djurovic Gary Donohoe Wayne C Drevets Ravi Duggirala Thomas D Dyer Christian Enzinger Susanne Erk Thomas Espeseth Iryna O Fedko Guillén Fernández Luigi Ferrucci Simon E Fisher Debra A Fleischman Ian Ford Myriam Fornage Tatiana M Foroud Peter T Fox Clyde Francks Masaki Fukunaga J Raphael Gibbs David C Glahn Randy L Gollub Harald H H Göring Robert C Green Oliver Gruber Vilmundur Gudnason Sebastian Guelfi Asta K Håberg Narelle K Hansell John Hardy Catharina A Hartman Ryota Hashimoto Katrin Hegenscheid Andreas Heinz Stephanie Le Hellard Dena G Hernandez Dirk J Heslenfeld Beng-Choon Ho Pieter J Hoekstra Wolfgang Hoffmann Albert Hofman Florian Holsboer Georg Homuth Norbert Hosten Jouke-Jan Hottenga Matthew Huentelman Hilleke E Hulshoff Pol Masashi Ikeda Clifford R Jack Mark Jenkinson Robert Johnson Erik G Jönsson J Wouter Jukema René S Kahn Ryota Kanai Iwona Kloszewska David S Knopman Peter Kochunov John B Kwok Stephen M Lawrie Hervé Lemaître Xinmin Liu Dan L Longo Oscar L Lopez Simon Lovestone Oliver Martinez Jean-Luc Martinot Venkata S Mattay Colm McDonald Andrew M McIntosh Francis J McMahon Katie L McMahon Patrizia Mecocci Ingrid Melle Andreas Meyer-Lindenberg Sebastian Mohnke Grant W Montgomery Derek W Morris Thomas H Mosley Thomas W Mühleisen Bertram Müller-Myhsok Michael A Nalls Matthias Nauck Thomas E Nichols Wiro J Niessen Markus M Nöthen Lars Nyberg Kazutaka Ohi Rene L Olvera Roel A Ophoff Massimo Pandolfo Tomas Paus Zdenka Pausova Brenda W J H Penninx G Bruce Pike Steven G Potkin Bruce M Psaty Simone Reppermund Marcella Rietschel Joshua L Roffman Nina Romanczuk-Seiferth Jerome I Rotter Mina Ryten Ralph L Sacco Perminder S Sachdev Andrew J Saykin Reinhold Schmidt Helena Schmidt Peter R Schofield Sigurdur Sigursson Andrew Simmons Andrew Singleton Sanjay M Sisodiya Colin Smith Jordan W Smoller Hilkka Soininen Vidar M Steen David J Stott Jessika E Sussmann Anbupalam Thalamuthu Arthur W Toga Bryan J Traynor Juan Troncoso Magda Tsolaki Christophe Tzourio Andre G Uitterlinden Maria C Valdés Hernández Marcel Van der Brug Aad van der Lugt Nic J A van der Wee Neeltje E M Van Haren Dennis van 't Ent Marie-Jose Van Tol Badri N Vardarajan Bruno Vellas Dick J Veltman Henry Völzke Henrik Walter Joanna M Wardlaw Thomas H Wassink Michael E Weale Daniel R Weinberger Michael W Weiner Wei Wen Eric Westman Tonya White Tien Y Wong Clinton B Wright Ronald H Zielke Alan B Zonderman Nicholas G Martin Cornelia M Van Duijn Margaret J Wright W T Longstreth Gunter Schumann Hans J Grabe Barbara Franke Lenore J Launer Sarah E Medland Sudha Seshadri Paul M Thompson M Arfan Ikram

Nat Commun 2017 01 18;8:13624. Epub 2017 Jan 18.

Department of Epidemiology, Erasmus University Medical Center, 3015 CE Rotterdam, The Netherlands.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5253632PMC
January 2017

Circulating vascular endothelial growth factor and the risk of cardiovascular events.

Heart 2016 12 27;102(23):1898-1901. Epub 2016 Jun 27.

National Heart, Lung and Blood Institute's Framingham Heart Study, Framingham, Massachusetts, USA.

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http://dx.doi.org/10.1136/heartjnl-2015-309155DOI Listing
December 2016

Novel genetic loci underlying human intracranial volume identified through genome-wide association.

Authors:
Hieab H H Adams Derrek P Hibar Vincent Chouraki Jason L Stein Paul A Nyquist Miguel E Rentería Stella Trompet Alejandro Arias-Vasquez Sudha Seshadri Sylvane Desrivières Ashley H Beecham Neda Jahanshad Katharina Wittfeld Sven J Van der Lee Lucija Abramovic Saud Alhusaini Najaf Amin Micael Andersson Konstantinos Arfanakis Benjamin S Aribisala Nicola J Armstrong Lavinia Athanasiu Tomas Axelsson Alexa Beiser Manon Bernard Joshua C Bis Laura M E Blanken Susan H Blanton Marc M Bohlken Marco P Boks Janita Bralten Adam M Brickman Owen Carmichael M Mallar Chakravarty Ganesh Chauhan Qiang Chen Christopher R K Ching Gabriel Cuellar-Partida Anouk Den Braber Nhat Trung Doan Stefan Ehrlich Irina Filippi Tian Ge Sudheer Giddaluru Aaron L Goldman Rebecca F Gottesman Corina U Greven Oliver Grimm Michael E Griswold Tulio Guadalupe Johanna Hass Unn K Haukvik Saima Hilal Edith Hofer David Hoehn Avram J Holmes Martine Hoogman Deborah Janowitz Tianye Jia Dalia Kasperaviciute Sungeun Kim Marieke Klein Bernd Kraemer Phil H Lee Jiemin Liao David C M Liewald Lorna M Lopez Michelle Luciano Christine Macare Andre Marquand Mar Matarin Karen A Mather Manuel Mattheisen Bernard Mazoyer David R McKay Rebekah McWhirter Yuri Milaneschi Nazanin Mirza-Schreiber Ryan L Muetzel Susana Muñoz Maniega Kwangsik Nho Allison C Nugent Loes M Olde Loohuis Jaap Oosterlaan Martina Papmeyer Irene Pappa Lukas Pirpamer Sara Pudas Benno Pütz Kumar B Rajan Adaikalavan Ramasamy Jennifer S Richards Shannon L Risacher Roberto Roiz-Santiañez Nanda Rommelse Emma J Rose Natalie A Royle Tatjana Rundek Philipp G Sämann Claudia L Satizabal Lianne Schmaal Andrew J Schork Li Shen Jean Shin Elena Shumskaya Albert V Smith Emma Sprooten Lachlan T Strike Alexander Teumer Russell Thomson Diana Tordesillas-Gutierrez Roberto Toro Daniah Trabzuni Dhananjay Vaidya Jeroen Van der Grond Dennis Van der Meer Marjolein M J Van Donkelaar Kristel R Van Eijk Theo G M Van Erp Daan Van Rooij Esther Walton Lars T Westlye Christopher D Whelan Beverly G Windham Anderson M Winkler Girma Woldehawariat Christiane Wolf Thomas Wolfers Bing Xu Lisa R Yanek Jingyun Yang Alex Zijdenbos Marcel P Zwiers Ingrid Agartz Neelum T Aggarwal Laura Almasy David Ames Philippe Amouyel Ole A Andreassen Sampath Arepalli Amelia A Assareh Sandra Barral Mark E Bastin Diane M Becker James T Becker David A Bennett John Blangero Hans van Bokhoven Dorret I Boomsma Henry Brodaty Rachel M Brouwer Han G Brunner Randy L Buckner Jan K Buitelaar Kazima B Bulayeva Wiepke Cahn Vince D Calhoun Dara M Cannon Gianpiero L Cavalleri Christopher Chen Ching-Yu Cheng Sven Cichon Mark R Cookson Aiden Corvin Benedicto Crespo-Facorro Joanne E Curran Michael Czisch Anders M Dale Gareth E Davies Eco J C De Geus Philip L De Jager Greig I de Zubicaray Norman Delanty Chantal Depondt Anita L DeStefano Allissa Dillman Srdjan Djurovic Gary Donohoe Wayne C Drevets Ravi Duggirala Thomas D Dyer Susanne Erk Thomas Espeseth Denis A Evans Iryna O Fedko Guillén Fernández Luigi Ferrucci Simon E Fisher Debra A Fleischman Ian Ford Tatiana M Foroud Peter T Fox Clyde Francks Masaki Fukunaga J Raphael Gibbs David C Glahn Randy L Gollub Harald H H Göring Hans J Grabe Robert C Green Oliver Gruber Vilmundur Gudnason Sebastian Guelfi Narelle K Hansell John Hardy Catharina A Hartman Ryota Hashimoto Katrin Hegenscheid Andreas Heinz Stephanie Le Hellard Dena G Hernandez Dirk J Heslenfeld Beng-Choon Ho Pieter J Hoekstra Wolfgang Hoffmann Albert Hofman Florian Holsboer Georg Homuth Norbert Hosten Jouke-Jan Hottenga Hilleke E Hulshoff Pol Masashi Ikeda M Kamran Ikram Clifford R Jack Mark Jenkinson Robert Johnson Erik G Jönsson J Wouter Jukema René S Kahn Ryota Kanai Iwona Kloszewska David S Knopman Peter Kochunov John B Kwok Stephen M Lawrie Hervé Lemaître Xinmin Liu Dan L Longo W T Longstreth Oscar L Lopez Simon Lovestone Oliver Martinez Jean-Luc Martinot Venkata S Mattay Colm McDonald Andrew M McIntosh Katie L McMahon Francis J McMahon Patrizia Mecocci Ingrid Melle Andreas Meyer-Lindenberg Sebastian Mohnke Grant W Montgomery Derek W Morris Thomas H Mosley Thomas W Mühleisen Bertram Müller-Myhsok Michael A Nalls Matthias Nauck Thomas E Nichols Wiro J Niessen Markus M Nöthen Lars Nyberg Kazutaka Ohi Rene L Olvera Roel A Ophoff Massimo Pandolfo Tomas Paus Zdenka Pausova Brenda W J H Penninx G Bruce Pike Steven G Potkin Bruce M Psaty Simone Reppermund Marcella Rietschel Joshua L Roffman Nina Romanczuk-Seiferth Jerome I Rotter Mina Ryten Ralph L Sacco Perminder S Sachdev Andrew J Saykin Reinhold Schmidt Peter R Schofield Sigurdur Sigurdsson Andy Simmons Andrew Singleton Sanjay M Sisodiya Colin Smith Jordan W Smoller Hilkka Soininen Velandai Srikanth Vidar M Steen David J Stott Jessika E Sussmann Anbupalam Thalamuthu Henning Tiemeier Arthur W Toga Bryan J Traynor Juan Troncoso Jessica A Turner Christophe Tzourio Andre G Uitterlinden Maria C Valdés Hernández Marcel Van der Brug Aad Van der Lugt Nic J A Van der Wee Cornelia M Van Duijn Neeltje E M Van Haren Dennis Van T Ent Marie-Jose Van Tol Badri N Vardarajan Dick J Veltman Meike W Vernooij Henry Völzke Henrik Walter Joanna M Wardlaw Thomas H Wassink Michael E Weale Daniel R Weinberger Michael W Weiner Wei Wen Eric Westman Tonya White Tien Y Wong Clinton B Wright H Ronald Zielke Alan B Zonderman Ian J Deary Charles DeCarli Helena Schmidt Nicholas G Martin Anton J M De Craen Margaret J Wright Lenore J Launer Gunter Schumann Myriam Fornage Barbara Franke Stéphanie Debette Sarah E Medland M Arfan Ikram Paul M Thompson

Nat Neurosci 2016 12 3;19(12):1569-1582. Epub 2016 Oct 3.

Imaging Genetics Center, USC Mark and Mary Stevens Neuroimaging and Informatics Institute, Keck School of Medicine of University of Southern California, Los Angeles, California, USA.

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http://dx.doi.org/10.1038/nn.4398DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5227112PMC
December 2016

Lifelong Reading Disorder and Mild Cognitive Impairment: Implications for Diagnosis.

J Alzheimers Dis 2016 ;50(1):41-5

Department of Neurology, Boston, University School of Medicine, Framingham Heart Study, Boston, MA, USA.

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http://dx.doi.org/10.3233/JAD-150543DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4827707PMC
October 2016

Aortic Stiffness and the Risk of Incident Mild Cognitive Impairment and Dementia.

Stroke 2016 09 4;47(9):2256-61. Epub 2016 Aug 4.

From the Department of Neurology, Boston University School of Medicine, MA (M.P.P., A.B., J.J.H., C.L.S., S.S.); Framingham Heart Study, MA (M.P.P., A.B., J.J.H., C.L.S., R.S.V., S.S., G.F.M.); Centre for Human Psychopharmacology, Swinburne University of Technology, Hawthorn, Australia (M.P.P.); Department of Biostatistics, Boston University School of Public Health, MA (A.B.); Department of Medicine, Cardiovascular Division, Beth Israel Deaconess Medical Centre, Boston, MA (C.T.); and Cardiovascular Engineering Inc, Norwood, MA (G.F.M.).

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http://dx.doi.org/10.1161/STROKEAHA.116.013508DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4995162PMC
September 2016

Circulating biomarkers and incident ischemic stroke in the Framingham Offspring Study.

Neurology 2016 Sep 24;87(12):1206-11. Epub 2016 Aug 24.

From the McMaster University and Population Health Research Institute (A.S.), Hamilton, Canada; Boston University School of Public Health (S.R.P., A.S.B., E.J.B.), Boston; and Boston University School of Medicine (A.S., A.S.B., C.S.K., P.A.W., R.S.V., E.J.B., S.S., J.R.R.), Boston, MA.

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http://www.neurology.org/lookup/doi/10.1212/WNL.000000000000
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5035987PMC
http://dx.doi.org/10.1212/WNL.0000000000003115DOI Listing
September 2016

Neck Circumference, Brain Imaging Measures, and Neuropsychological Testing Measures.

J Stroke Cerebrovasc Dis 2016 Jul 4;25(7):1570-1581. Epub 2016 Apr 4.

National Heart, Lung, and Blood Institute's Framingham Heart Study, Framingham, Massachusetts; Division of Endocrinology and Metabolism, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts. Electronic address:

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July 2016

Plasma clusterin levels and risk of dementia, Alzheimer's disease, and stroke.

Alzheimers Dement (Amst) 2016 9;3:103-9. Epub 2016 Jul 9.

Framingham Heart Study, Framingham, MA, USA; Department of Neurology, Boston University School of Medicine, Boston, MA, USA.

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http://dx.doi.org/10.1016/j.dadm.2016.06.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4949604PMC
July 2016

Association of Physical Function with Clinical and Subclinical Brain Disease: The Framingham Offspring Study.

J Alzheimers Dis 2016 07;53(4):1597-608

Department of Neurology, School of Medicine, Boston University, Boston, Massachusetts.

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http://dx.doi.org/10.3233/JAD-160229DOI Listing
July 2016

Midlife Hypertension Risk and Cognition in the Non-Demented Oldest Old: Framingham Heart Study.

J Alzheimers Dis 2015 ;47(1):197-204

Framingham Heart Study, Department of Neurology, Boston University School of Medicine, Boston, MA, USA.

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http://dx.doi.org/10.3233/JAD-141881DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4827717PMC
June 2016

Association of Ideal Cardiovascular Health With Vascular Brain Injury and Incident Dementia.

Stroke 2016 05 12;47(5):1201-6. Epub 2016 Apr 12.

From the Department of Neurology (M.P.P., A.B., H.A., C.L.S., J.J.H., S.S.), and Section of Preventive Medicine, Department of Medicine (D.E., V.X., R.S.V.), Boston University School of Medicine and Framingham Heart Study (M.P.P., A.B., D.E., V.X., H.A., C.L.S., J.J.H., R.S.V., S.S.), Boston, MA; Centre for Human Psychopharmacology, Swinburne University of Technology, Melbourne, Victoria, Australia (M.P.P.); Department of Biostatistics, Boston University School of Public Health, MA (A.B.); Department of Neurology, Boston Medical Centre, MA (H.A., C.S.K.); and Department of Neurology, School of Medicine and Imaging of Dementia and Aging Laboratory, Center for Neuroscience, University of California Davis, Sacramento (C.D.).

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http://stroke.ahajournals.org/content/early/2016/04/12/STROK
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http://dx.doi.org/10.1161/STROKEAHA.115.012608DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5006676PMC
May 2016

Interarm differences in systolic blood pressure and the risk of dementia and subclinical brain injury.

Alzheimers Dement 2016 Apr 2;12(4):438-45. Epub 2015 Nov 2.

Boston University School of Medicine & Framingham Heart Study, Boston, MA, USA.

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http://dx.doi.org/10.1016/j.jalz.2015.09.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4841714PMC
April 2016

Midlife exercise blood pressure, heart rate, and fitness relate to brain volume 2 decades later.

Neurology 2016 Apr 10;86(14):1313-1319. Epub 2016 Feb 10.

From the Section of Preventive Medicine and Epidemiology (N.L.S., R.S.V.), The Whitaker Cardiovascular Institute (N.L.S.), and Department of Neurology (J.J.H., A.S.B., S.S.), Boston University School of Medicine; the Framingham Heart Study (N.L.S., J.J.H., A.S.B., R.S.V., S.S.); Departments of Biostatistics (A.S.B.) and Epidemiology (R.S.V.), Boston University School of Public Health; Cardiology Division (G.D.L.) and the Pulmonary and Critical Care Unit (G.D.L.), Massachusetts General Hospital, Harvard Medical School; Broad Institute of MIT & Harvard (G.D.L.), Cambridge, MA; and Department of Neurology and Center for Neuroscience (C.D.), University of California at Davis.

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http://dx.doi.org/10.1212/WNL.0000000000002415DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4826343PMC
April 2016

Effects of Arterial Stiffness on Brain Integrity in Young Adults From the Framingham Heart Study.

Stroke 2016 Apr 10;47(4):1030-6. Epub 2016 Mar 10.

From the Imaging of Dementia and Aging (IDeA) Laboratory, Davis, CA (P.M.); Department of Neurology and Center for Neurosciences, University of California, Davis, CA (P.M., C.D.); Cardiovascular Engineering, Inc, Norwood, MA (G.F.M.); The Framingham Heart Study, MA (J.J.H., A.B., M.P.P., C.L.S., S.S.); Boston University School of Medicine, MA (J.J.H., A.B., M.P.P., C.L.S., R.S.V., S.S.); Department of Biostatistics, Boston University School of Public Health, MA (A.B.); Cardiovascular Division, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA (C.W.T.); and Centre for Human Psychopharmacology, Swinburne University of Technology, Hawthorn, Australia (M.P.P.).

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4811686PMC
April 2016

Factors Associated With New-Onset Depression After Stroke.

J Neuropsychiatry Clin Neurosci 2016 8;28(4):286-291. Epub 2016 Apr 8.

From the Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston (JS, JR); The Framingham Heart Study, Boston (AB, JJH, SS); the Department of Biostatistics, Boston University School of Medicine, Boston (AB); the Department of Neurology, Boston University School of Medicine, Boston (AB, SS); and the Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School, Boston (ECD).

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5474200PMC
April 2016

Association of Aortic Stiffness With Cognition and Brain Aging in Young and Middle-Aged Adults: The Framingham Third Generation Cohort Study.

Hypertension 2016 Mar 11;67(3):513-9. Epub 2016 Jan 11.

From the Department of Neurology, Boston University School of Medicine, MA (M.P.P., J.J.H., A.B., S.S.); Framingham Heart Study, MA (M.P.P., J.J.H., G.F.M., A.B., M.G.L., R.S.V., S.S.); Centre for Human Psychopharmacology, Swinburne University of Technology, Melbourne, Victoria, Australia (M.P.P.); Cardiovascular Engineering Inc, Norwood, MA (G.F.M.); Department of Biostatistics, Boston University School of Public Health, MA (A.B.); Department of Neurology, School of Medicine and Imaging of Dementia and Aging Laboratory, Center for Neuroscience, University of California Davis, Sacramento (P.M., C.D.); and Cardiovascular Division, Department of Medicine, Beth Israel Deaconess Medical Centre, Boston, MA (C.T.).

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http://dx.doi.org/10.1161/HYPERTENSIONAHA.115.06610DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4752398PMC
March 2016

Silent Brain Infarction and Risk of Future Stroke: A Systematic Review and Meta-Analysis.

Stroke 2016 Mar;47(3):719-25

From the Department of Radiology (A.G., C.F.), Feil Family Brain and Mind Research Institute (A.G., G.G., H.K.), Department of Healthcare Policy and Research (A.E.G.), Samuel J. Wood Library and C.V. Starr Biomedical Information Center (D.D.), Department of Neurology (H.K.), Weill Cornell Medical College, New York, NY; Department of Neurology, Columbia University Medical Center, New York, NY (J.G.); Department of Neurology, University of Miami Miller School of Medicine, FL (C.W.); Department of Biostatistics, Boston University School of Public Health, MA (A.S.B.); Department of Neurology, Boston University School of Medicine, MA (S.S.); and Department of Health Policy and Management, Harvard T.H. Chan School of Public Health, Boston, MA (A.P.).

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http://dx.doi.org/10.1161/STROKEAHA.115.011889DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4766016PMC
March 2016

Carotid Atherosclerosis and Cerebral Microbleeds: The Framingham Heart Study.

J Am Heart Assoc 2016 Mar 18;5(3):e002377. Epub 2016 Mar 18.

Department of Neurology, School of Public Health at Boston University, Boston, MA NHLBI's Framingham Heart Study, Framingham, MA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4943235PMC
March 2016

Association of Exhaled Carbon Monoxide With Stroke Incidence and Subclinical Vascular Brain Injury: Framingham Heart Study.

Stroke 2016 Feb 22;47(2):383-9. Epub 2015 Dec 22.

From the Framingham Heart Study, MA (M.N., A.S.B., S.C., R.S.V., S.S.); Division of Cardiovascular Medicine, Brigham and Women's Hospital, Boston, MA (M.N., S.C.); Departments of Biostatistics (D.M.E., A.S.B.) and Epidemiology (R.S.V.), Boston University School of Public Health, MA; Department of Neurology (A.S.B., S.S) and Sections of Preventive Medicine & Epidemiology and Cardiology, Department of Medicine (R.S.V.), Boston University School of Medicine, MA; and Department of Neurology and Center for Neuroscience, University of California at Davis (C.D.).

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4729607PMC
February 2016

Association of arterial stiffness with progression of subclinical brain and cognitive disease.

Neurology 2016 Feb 20;86(7):619-26. Epub 2016 Jan 20.

From the Department of Medicine (C.W.T.), Cardiovascular Division, Beth Israel Deaconess Medical Center, Boston, MA; Departments of Neurology (J.J.H., A.S.B., S.S.) and Medicine (R.S.V.), School of Medicine, Departments of Biostatistics (J.J.H., A.S.B.) and Epidemiology (R.S.V.), School of Public Health, and the Department of Mathematics and Statistics (M.G.L.), Boston University, Boston, MA; Department of Neurology and Center for Neuroscience and Division of Biostatistics (C.D.), Department of Public Health Sciences, School of Medicine, University of California, Davis, CA; The Framingham Heart Study (C.W.T., J.J.H., A.S.B., M.G.L., R.S.V., S.S.), Framingham, MA; and Cardiovascular Engineering Inc. (G.F.M.), Norwood, MA.

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http://dx.doi.org/10.1212/WNL.0000000000002368DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4762417PMC
February 2016

Incidence of Dementia over Three Decades in the Framingham Heart Study.

N Engl J Med 2016 Feb;374(6):523-32

From the Boston University Schools of Medicine (C.L.S., A.S.B., V.C., S.S.) and Public Health (A.S.B.), Boston, and the Framingham Heart Study, Framingham (C.L.S., A.S.B., V.C., S.S.) - all in Massachusetts; and Inserm Unité 1219 and CIC 1401-EC (Clinical Epidemiology) and University of Bordeaux, ISPED (Bordeaux School of Public Health) - both in Bordeaux, France (G.C., C.D.).

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http://dx.doi.org/10.1056/NEJMoa1504327DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4943081PMC
February 2016

White Matter Lesion Progression: Genome-Wide Search for Genetic Influences.

Stroke 2015 Nov 8;46(11):3048-57. Epub 2015 Oct 8.

From the Department of Neurology (E.H., M.C., H.S., R.S.) and Institute for Medical Informatics, Statistics and Documentation (E.H.), Medical University of Graz, Graz, Austria; Cardiovascular Health Research Unit, Departments of Medicine (J.C.B., B.M.P.), Radiology (D.K.S.), and Neurology and Epidemiology (W.T.L.), University of Washington, Seattle; Department of Neurology and Center for Neuroscience, University of California at Davis, Sacramento (C.D.C., O.M.); Brown Foundation Institute of Molecular Medicine (M.F.) and Human Genetics Center (M.F.), University of Texas Health Science Center, Houston; Icelandic Heart Association, Kopavogur, Iceland (S.S., V.G., A.S.); Stroke and Ageing Research Group, Department of Medicine, Southern Clinical School, Monash University, Melbourne, Victoria, Australia (V.S., M.C., C.M., T.P., R.B.); Departments of Cardiology (S.T., J.W.J.), Gerontology and Geriatrics (S.T., A.J.M.C., R.G.J.W.), Molecular Epidemiology (P.E.S.), and Radiology (M.B.), Leiden University Medical Center, Leiden, The Netherlands; Departments of Epidemiology (B.F.J.V., H.H.H.A., C.M.D., A.H., M.W.V., M.A.I.), Radiology (B.F.J.V., H.H.H.A., M.W.V., M.A.I.), and Medical Informatics (W.J.N.), Erasmus Medical Center, Rotterdam, The Netherlands; INSERM U897 (C.W., G.C., C.D., S.S., S.D.), CNRS-CEA UMR5296 (B.M.), and INSERM U708 (C.T.), Université Bordeaux Segalen, Bordeaux, France; Department of Statistical Genetics, Max Planck Institute of Psychiatry, Munich, Germany (C.W.); Department of Biostatistics, Boston University School of Public Health, MA (Q.Y., A.B., J.W.); INSERM U744, Pasteur Institute, Lille, France (P.A.); Department of Pharmacology and Therapeutics, University College Cork, Cork, Ireland (B.M.B.); INSERM U1161 and Lariboisière Hospital, Paris 7 University, Paris, France (G.C., S.S., S.D.); Centre for Medical Systems Biology, Leiden, The Netherlands (C.M.D.); Robertson Center for Biostatistics, University of Glasgow, Glasgow, United Kingdom (I.F

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4749149PMC
November 2015

Spectrum of cognition short of dementia: Framingham Heart Study and Mayo Clinic Study of Aging.

Neurology 2015 Nov 9;85(19):1712-21. Epub 2015 Oct 9.

From the Department of Neurology, Mayo Alzheimer's Disease Research Center (D.S.K., B.F.B., R.C.P., R.O.R., W.A.R.), Division of Epidemiology, Department of Health Sciences Research (R.O.R., M.M. Mielke, W.A.R., R.C.P.), Division of Biostatistics and Bioinformatics, Department of Health Sciences Research (V.S.P., J.A., R.H.C.), and Department of Psychiatry and Psychology, Division of Neurocognitive Disorders (R.J.I., M.M. Machulda, J.F.), College of Medicine, Mayo Clinic, Rochester, MN; and Departments of Neurology (A.B., S.D., R.A., S.A., P.A.W., S.S.) and Biostatistics (A.B.), Boston University Schools of Medicine and Public Health, MA.

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http://dx.doi.org/10.1212/WNL.0000000000002100DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4653114PMC
November 2015

Serum Leptin Levels and the Risk of Stroke: The Framingham Study.

Stroke 2015 Oct 3;46(10):2881-5. Epub 2015 Sep 3.

From the Framingham Heart Study, MA (H.S., A.B., J.R.R., C.S.K., R.S.V., S.S.); Department of Biostatistics, Boston University School of Public Health, MA (A.B.); Division of Neurology, Department of Medicine, McMaster University/Population Health Research Institute, Hamilton, ON, Canada (A.S.); Department of Neurology, University of Toronto, Toronto, ON, Canada (A.P.); Geriatric Epidemiology section, National Institute on Aging, National Institute of Health, Bethesda, MD (T.B.H.); Friedman School of Nutrition Science and Policy, Tufts University School of Medicine, Boston, MA (R.R.); and Department of Neurology, Boston University School of Medicine, MA (H.S., J.J.H., A.B., J.R.R., C.S.K., R.S.V., S.S.).

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http://dx.doi.org/10.1161/STROKEAHA.115.009463DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4589501PMC
October 2015

Verbal memory and brain aging: an exploratory analysis of the role of error responses in the Framingham Study.

Am J Alzheimers Dis Other Demen 2015 Sep 18;30(6):622-8. Epub 2015 Mar 18.

Department of Biostatistics, Boston University School of Public, Boston, MA, USA Boston University School of Medicine, Boston, MA, USA.

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http://dx.doi.org/10.1177/1533317515577184DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4536169PMC
September 2015

Associations of Circulating Growth Differentiation Factor-15 and ST2 Concentrations With Subclinical Vascular Brain Injury and Incident Stroke.

Stroke 2015 Sep 28;46(9):2568-75. Epub 2015 Jul 28.

From the Framingham Heart Study, MA (C.A., A.B., T.J.W., R.S.V., S.S.); Department of Cardiology, Gentofte Hospital, University of Copenhagen, Denmark (C.A.); Department of Biostatistics, Boston University School of Public Health, MA (S.R.P., A.B.); Department of Neurology (A.B., S.S.) and Section of Preventive Medicine and Cardiology (R.S.V.), Boston University School of Medicine, MA; Department of Neurology, University of California at Davis, Sacramento (C.D.); Division of Molecular and Translational Cardiology, Department of Cardiology and Angiology, Hannover Medical School, Hannover, Germany (K.C.W.); Division of Cardiovascular Medicine, Vanderbilt University, Nashville, TN (T.J.W.); and Division of Cardiology, Massachusetts General Hospital, Harvard Medical School, Boston (J.L.J.).

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http://dx.doi.org/10.1161/STROKEAHA.115.009026DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4550531PMC
September 2015

50 year trends in atrial fibrillation prevalence, incidence, risk factors, and mortality in the Framingham Heart Study: a cohort study.

Lancet 2015 Jul 7;386(9989):154-62. Epub 2015 May 7.

National Heart, Lung, and Blood Institute's Framingham Study, Framingham, MA, USA; Preventive Medicine Section, School of Medicine, Boston University, Boston, MA, USA; Population Sciences Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, USA.

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http://dx.doi.org/10.1016/S0140-6736(14)61774-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4553037PMC
July 2015

Glucose indices are associated with cognitive and structural brain measures in young adults.

Neurology 2015 Jun 6;84(23):2329-37. Epub 2015 May 6.

From the Department of Neurology (G.W., J.J.H., A.S.B., R.A., P.A.W., S.S.), Boston University School of Medicine, MA; The Framingham Heart Study (G.W., J.J.H., A.S.B., R.A., P.A.W., S.S.), MA; the Department of Neurology (P.M., C.D.), The University of California at Davis, Sacramento; and the Department of Biostatistics (A.S.B.), Boston University School of Public Health, MA.

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http://dx.doi.org/10.1212/WNL.0000000000001655DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4464744PMC
June 2015

Long-term exposure to fine particulate matter, residential proximity to major roads and measures of brain structure.

Stroke 2015 May;46(5):1161-6

From the Cardiovascular Epidemiology Research Unit, Department of Medicine, Beth Israel Deaconess Medical Center, Boston, MA (E.H.W., M.A.M.); Exposure, Epidemiology and Risk Program, Department of Environmental Health (E.H.W., J.S., P.K.) and Department of Epidemiology (W.L., J.S., M.A.M.), Harvard T.H. Chan School of Public Health, Boston, MA; Department of Biostatistics, School of Public Health (S.R.P., A.S.B., R.A.) and Department of Neurology, School of Medicine (A.S.B., P.A.W., S.S.), Boston University, MA; Framingham Heart Study, MA (S.R.P., A.S.B., P.A.W., S.S.); Department of Geography and Environmental Development, Ben-Gurion University of the Negev, Beer Sheva, Israel (I.K.); and Department of Neurology and Center for Neuroscience, University of California, Davis (C.D.).

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http://stroke.ahajournals.org/cgi/doi/10.1161/STROKEAHA.114.
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http://dx.doi.org/10.1161/STROKEAHA.114.008348DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4414870PMC
May 2015