Publications by authors named "Alex Lipovsky"

14Publications

Small Molecule and Pooled CRISPR Screens Investigating IL17 Signaling Identify BRD2 as a Novel Contributor to Keratinocyte Inflammatory Responses.

ACS Chem Biol 2019 05 15;14(5):857-872. Epub 2019 Apr 15.

Discovery Dermatology & Fibrosis , AbbVie Bioresearch Center , Worcester , Massachusetts 01605 , United States.

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May 2019

The cellular endosomal protein stannin inhibits intracellular trafficking of human papillomavirus during virus entry.

Authors:

Alex Lipovsky Asu Erden Eriko Kanaya Wei Zhang Mac Crite Clinton Bradfield John MacMicking Daniel DiMaio John W Schoggins Akiko Iwasaki

J Gen Virol 2017 11 23;98(11):2821-2836. Epub 2017 Oct 23.

Department of Immunobiology, Yale School of Medicine, New Haven, CT 06520-8011, P.O. Box 208011, USA.

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November 2017

Application of the proximity-dependent assay and fluorescence imaging approaches to study viral entry pathways.

Authors:

Alex Lipovsky Wei Zhang Akiko Iwasaki Daniel DiMaio

Methods Mol Biol 2015 ;1270:437-51

Department of Immunobiology, Yale School of Medicine, New Haven, CT, 06520-8011, USA.

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November 2015

Direct binding of retromer to human papillomavirus type 16 minor capsid protein L2 mediates endosome exit during viral infection.

Authors:

Andreea Popa Wei Zhang Megan S Harrison Kylia Goodner Teymur Kazakov Edward C Goodwin Alex Lipovsky Christopher G Burd Daniel DiMaio

PLoS Pathog 2015 Feb 18;11(2):e1004699. Epub 2015 Feb 18.

Department of Genetics, Yale School of Medicine, New Haven, Connecticut, United States of America; Department of Therapeutic Radiology, Yale School of Medicine, New Haven, Connecticut, United States of America; Department of Molecular Biophysics & Biochemistry, Yale School of Medicine, New Haven, Connecticut, United States of America; Yale Cancer Center, New Haven, Connecticut, United States of America.

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February 2015

Structural optimization of a retrograde trafficking inhibitor that protects cells from infections by human polyoma- and papillomaviruses.

Authors:

Daniel W Carney Christian D S Nelson Bennett D Ferris Julia P Stevens Alex Lipovsky Teymur Kazakov Daniel DiMaio Walter J Atwood Jason K Sello

Bioorg Med Chem 2014 Sep 10;22(17):4836-47. Epub 2014 Jul 10.

Department of Chemistry, Brown University, 324 Brook Street, Providence, RI 02912, United States. Electronic address:

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September 2014

Expression of DNAJB12 or DNAJB14 causes coordinate invasion of the nucleus by membranes associated with a novel nuclear pore structure.

Authors:

Edward C Goodwin Nasim Motamedi Alex Lipovsky Rubén Fernández-Busnadiego Daniel DiMaio

PLoS One 2014 14;9(4):e94322. Epub 2014 Apr 14.

Department of Genetics, Yale School of Medicine, New Haven, Connecticut, United States of America; Department of Therapeutic Radiology, Yale School of Medicine, New Haven, Connecticut, United States of America; Department of Molecular Biophysics & Biochemistry, Yale School of Medicine, New Haven, Connecticut, United States of America; Yale Cancer Center, New Haven, Connecticut, United States of America.

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January 2015

A retrograde trafficking inhibitor of ricin and Shiga-like toxins inhibits infection of cells by human and monkey polyomaviruses.

Authors:

Christian D S Nelson Dan W Carney Aaron Derdowski Alex Lipovsky Gretchen V Gee Bethany O'Hara Paul Williard Daniel DiMaio Jason K Sello Walter J Atwood

mBio 2013 Nov 12;4(6):e00729-13. Epub 2013 Nov 12.

Department of Molecular Biology, Cell Biology, and Biochemistry, Brown University, Providence, Rhode Island, USA.

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November 2013

Genome-wide siRNA screen identifies the retromer as a cellular entry factor for human papillomavirus.

Authors:

Alex Lipovsky Andreea Popa Genaro Pimienta Michael Wyler Ashima Bhan Leena Kuruvilla Marie-Aude Guie Adrian C Poffenberger Christian D S Nelson Walter J Atwood Daniel DiMaio

Proc Natl Acad Sci U S A 2013 Apr 8;110(18):7452-7. Epub 2013 Apr 8.

Department of Immunobiology, Yale School of Medicine, New Haven, CT 06520-8011, USA.

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April 2013

Akt stimulates hepatic SREBP1c and lipogenesis through parallel mTORC1-dependent and independent pathways.

Authors:

Jessica L Yecies Hui H Zhang Suchithra Menon Sihao Liu Derek Yecies Alex I Lipovsky Cem Gorgun David J Kwiatkowski Gökhan S Hotamisligil Chih-Hao Lee Brendan D Manning

Cell Metab 2011 Jul;14(1):21-32

Department of Genetics and Complex Diseases, Harvard School of Public Health, Boston, MA 02115, USA.

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July 2011

BiP and multiple DNAJ molecular chaperones in the endoplasmic reticulum are required for efficient simian virus 40 infection.

Authors:

Edward C Goodwin Alex Lipovsky Takamasa Inoue Thomas G Magaldi Anne P B Edwards Kristin E Y Van Goor Adrienne W Paton James C Paton Walter J Atwood Billy Tsai Daniel DiMaio

mBio 2011 14;2(3):e00101-11. Epub 2011 Jun 14.

Department of Genetics, Yale School of Medicine, New Haven, Connecticut, USA.

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October 2011

Activation of a metabolic gene regulatory network downstream of mTOR complex 1.

Authors:

Katrin Düvel Jessica L Yecies Suchithra Menon Pichai Raman Alex I Lipovsky Amanda L Souza Ellen Triantafellow Qicheng Ma Regina Gorski Stephen Cleaver Matthew G Vander Heiden Jeffrey P MacKeigan Peter M Finan Clary B Clish Leon O Murphy Brendan D Manning

Mol Cell 2010 Jul;39(2):171-83

Department of Genetics and Complex Diseases, Harvard School of Public Health, Boston, MA 02115, USA.

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July 2010

Evolution of genes and genomes on the Drosophila phylogeny.

Authors:

Andrew G Clark Michael B Eisen Douglas R Smith Casey M Bergman Brian Oliver Therese A Markow Thomas C Kaufman Manolis Kellis William Gelbart Venky N Iyer Daniel A Pollard Timothy B Sackton Amanda M Larracuente Nadia D Singh Jose P Abad Dawn N Abt Boris Adryan Montserrat Aguade Hiroshi Akashi Wyatt W Anderson Charles F Aquadro David H Ardell Roman Arguello Carlo G Artieri Daniel A Barbash Daniel Barker Paolo Barsanti Phil Batterham Serafim Batzoglou Dave Begun Arjun Bhutkar Enrico Blanco Stephanie A Bosak Robert K Bradley Adrianne D Brand Michael R Brent Angela N Brooks Randall H Brown Roger K Butlin Corrado Caggese Brian R Calvi A Bernardo de Carvalho Anat Caspi Sergio Castrezana Susan E Celniker Jean L Chang Charles Chapple Sourav Chatterji Asif Chinwalla Alberto Civetta Sandra W Clifton Josep M Comeron James C Costello Jerry A Coyne Jennifer Daub Robert G David Arthur L Delcher Kim Delehaunty Chuong B Do Heather Ebling Kevin Edwards Thomas Eickbush Jay D Evans Alan Filipski Sven Findeiss Eva Freyhult Lucinda Fulton Robert Fulton Ana C L Garcia Anastasia Gardiner David A Garfield Barry E Garvin Greg Gibson Don Gilbert Sante Gnerre Jennifer Godfrey Robert Good Valer Gotea Brenton Gravely Anthony J Greenberg Sam Griffiths-Jones Samuel Gross Roderic Guigo Erik A Gustafson Wilfried Haerty Matthew W Hahn Daniel L Halligan Aaron L Halpern Gillian M Halter Mira V Han Andreas Heger LaDeana Hillier Angie S Hinrichs Ian Holmes Roger A Hoskins Melissa J Hubisz Dan Hultmark Melanie A Huntley David B Jaffe Santosh Jagadeeshan William R Jeck Justin Johnson Corbin D Jones William C Jordan Gary H Karpen Eiko Kataoka Peter D Keightley Pouya Kheradpour Ewen F Kirkness Leonardo B Koerich Karsten Kristiansen Dave Kudrna Rob J Kulathinal Sudhir Kumar Roberta Kwok Eric Lander Charles H Langley Richard Lapoint Brian P Lazzaro So-Jeong Lee Lisa Levesque Ruiqiang Li Chiao-Feng Lin Michael F Lin Kerstin Lindblad-Toh Ana Llopart Manyuan Long Lloyd Low Elena Lozovsky Jian Lu Meizhong Luo Carlos A Machado Wojciech Makalowski Mar Marzo Muneo Matsuda Luciano Matzkin Bryant McAllister Carolyn S McBride Brendan McKernan Kevin McKernan Maria Mendez-Lago Patrick Minx Michael U Mollenhauer Kristi Montooth Stephen M Mount Xu Mu Eugene Myers Barbara Negre Stuart Newfeld Rasmus Nielsen Mohamed A F Noor Patrick O'Grady Lior Pachter Montserrat Papaceit Matthew J Parisi Michael Parisi Leopold Parts Jakob S Pedersen Graziano Pesole Adam M Phillippy Chris P Ponting Mihai Pop Damiano Porcelli Jeffrey R Powell Sonja Prohaska Kim Pruitt Marta Puig Hadi Quesneville Kristipati Ravi Ram David Rand Matthew D Rasmussen Laura K Reed Robert Reenan Amy Reily Karin A Remington Tania T Rieger Michael G Ritchie Charles Robin Yu-Hui Rogers Claudia Rohde Julio Rozas Marc J Rubenfield Alfredo Ruiz Susan Russo Steven L Salzberg Alejandro Sanchez-Gracia David J Saranga Hajime Sato Stephen W Schaeffer Michael C Schatz Todd Schlenke Russell Schwartz Carmen Segarra Rama S Singh Laura Sirot Marina Sirota Nicholas B Sisneros Chris D Smith Temple F Smith John Spieth Deborah E Stage Alexander Stark Wolfgang Stephan Robert L Strausberg Sebastian Strempel David Sturgill Granger Sutton Granger G Sutton Wei Tao Sarah Teichmann Yoshiko N Tobari Yoshihiko Tomimura Jason M Tsolas Vera L S Valente Eli Venter J Craig Venter Saverio Vicario Filipe G Vieira Albert J Vilella Alfredo Villasante Brian Walenz Jun Wang Marvin Wasserman Thomas Watts Derek Wilson Richard K Wilson Rod A Wing Mariana F Wolfner Alex Wong Gane Ka-Shu Wong Chung-I Wu Gabriel Wu Daisuke Yamamoto Hsiao-Pei Yang Shiaw-Pyng Yang James A Yorke Kiyohito Yoshida Evgeny Zdobnov Peili Zhang Yu Zhang Aleksey V Zimin Jennifer Baldwin Amr Abdouelleil Jamal Abdulkadir Adal Abebe Brikti Abera Justin Abreu St Christophe Acer Lynne Aftuck Allen Alexander Peter An Erica Anderson Scott Anderson Harindra Arachi Marc Azer Pasang Bachantsang Andrew Barry Tashi Bayul Aaron Berlin Daniel Bessette Toby Bloom Jason Blye Leonid Boguslavskiy Claude Bonnet Boris Boukhgalter Imane Bourzgui Adam Brown Patrick Cahill Sheridon Channer Yama Cheshatsang Lisa Chuda Mieke Citroen Alville Collymore Patrick Cooke Maura Costello Katie D'Aco Riza Daza Georgius De Haan Stuart DeGray Christina DeMaso Norbu Dhargay Kimberly Dooley Erin Dooley Missole Doricent Passang Dorje Kunsang Dorjee Alan Dupes Richard Elong Jill Falk Abderrahim Farina Susan Faro Diallo Ferguson Sheila Fisher Chelsea D Foley Alicia Franke Dennis Friedrich Loryn Gadbois Gary Gearin Christina R Gearin Georgia Giannoukos Tina Goode Joseph Graham Edward Grandbois Sharleen Grewal Kunsang Gyaltsen Nabil Hafez Birhane Hagos Jennifer Hall Charlotte Henson Andrew Hollinger Tracey Honan Monika D Huard Leanne Hughes Brian Hurhula M Erii Husby Asha Kamat Ben Kanga Seva Kashin Dmitry Khazanovich Peter Kisner Krista Lance Marcia Lara William Lee Niall Lennon Frances Letendre Rosie LeVine Alex Lipovsky Xiaohong Liu Jinlei Liu Shangtao Liu Tashi Lokyitsang Yeshi Lokyitsang Rakela Lubonja Annie Lui Pen MacDonald Vasilia Magnisalis Kebede Maru Charles Matthews William McCusker Susan McDonough Teena Mehta James Meldrim Louis Meneus Oana Mihai Atanas Mihalev Tanya Mihova Rachel Mittelman Valentine Mlenga Anna Montmayeur Leonidas Mulrain Adam Navidi Jerome Naylor Tamrat Negash Thu Nguyen Nga Nguyen Robert Nicol Choe Norbu Nyima Norbu Nathaniel Novod Barry O'Neill Sahal Osman Eva Markiewicz Otero L Oyono Christopher Patti Pema Phunkhang Fritz Pierre Margaret Priest Sujaa Raghuraman Filip Rege Rebecca Reyes Cecil Rise Peter Rogov Keenan Ross Elizabeth Ryan Sampath Settipalli Terry Shea Ngawang Sherpa Lu Shi Diana Shih Todd Sparrow Jessica Spaulding John Stalker Nicole Stange-Thomann Sharon Stavropoulos Catherine Stone Christopher Strader Senait Tesfaye Talene Thomson Yama Thoulutsang Dawa Thoulutsang Kerri Topham Ira Topping Tsamla Tsamla Helen Vassiliev Andy Vo Tsering Wangchuk Tsering Wangdi Michael Weiand Jane Wilkinson Adam Wilson Shailendra Yadav Geneva Young Qing Yu Lisa Zembek Danni Zhong Andrew Zimmer Zac Zwirko David B Jaffe Pablo Alvarez Will Brockman Jonathan Butler CheeWhye Chin Sante Gnerre Manfred Grabherr Michael Kleber Evan Mauceli Iain MacCallum

Nature 2007 Nov;450(7167):203-18

Department of Molecular Biology and Genetics, Cornell University, Ithaca, New York 14853, USA.

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November 2007

S6K1 regulates GSK3 under conditions of mTOR-dependent feedback inhibition of Akt.

Authors:

Hui H Zhang Alex I Lipovsky Christian C Dibble Mustafa Sahin Brendan D Manning

Mol Cell 2006 Oct;24(2):185-97

Department of Genetics and Complex Diseases, Harvard School of Public Health, Harvard Medical School, Boston, Massachusetts 02115, USA.

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October 2006

Feedback inhibition of Akt signaling limits the growth of tumors lacking Tsc2.

Authors:

Brendan D Manning M Nicole Logsdon Alex I Lipovsky Derek Abbott David J Kwiatkowski Lewis C Cantley

Genes Dev 2005 Aug 18;19(15):1773-8. Epub 2005 Jul 18.

Department of Genetics and Complex Diseases, Harvard School of Public Health, Boston, Massachusetts 02115, USA.

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August 2005