Publications by authors named "Alex J Sutton"

93Publications

Uptake of methodological advances for synthesis of continuous and time-to-event outcomes would maximize use of the evidence base.

J Clin Epidemiol 2020 Aug 12;124:94-105. Epub 2020 May 12.

Department of Health Sciences, University of Leicester, Leicester LE1 7RH, UK.

View Article and Find Full Text PDF
August 2020

A comparison of the statistical performance of different meta-analysis models for the synthesis of subgroup effects from randomized clinical trials.

BMC Med Res Methodol 2019 10 26;19(1):198. Epub 2019 Oct 26.

Department of Health Sciences, University of Leicester, Leicester, UK.

View Article and Find Full Text PDF
October 2019

Synthesizing existing evidence to design future trials: survey of methodologists from European institutions.

Trials 2019 Jun 7;20(1):334. Epub 2019 Jun 7.

Institute of Social and Preventive Medicine (ISPM), University of Bern, Bern, Switzerland.

View Article and Find Full Text PDF
June 2019

Development of an interactive web-based tool to conduct and interrogate meta-analysis of diagnostic test accuracy studies: MetaDTA.

BMC Med Res Methodol 2019 04 18;19(1):81. Epub 2019 Apr 18.

NIHR Complex Reviews Support Unit, University of Leicester & University of Glasgow, Glasgow, UK.

View Article and Find Full Text PDF
April 2019

AD-8 for detection of dementia across a variety of healthcare settings.

Cochrane Database Syst Rev 2019 03 4;3:CD011121. Epub 2019 Mar 4.

Institute of Cardiovascular and Medical Sciences, University of Glasgow, New Lister Building, Glasgow Royal Infirmary, Glasgow, UK, G4 OSF.

View Article and Find Full Text PDF
March 2019

The Value of Further Research: The Added Value of Individual-Participant Level Data.

Appl Health Econ Health Policy 2019 06;17(3):273-284

Centre for Health Economics, The University of York, York, UK.

View Article and Find Full Text PDF
June 2019

Use of a random effects meta-analysis in the design and analysis of a new clinical trial.

Stat Med 2018 12 6;37(30):4665-4679. Epub 2018 Sep 6.

Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.

View Article and Find Full Text PDF
December 2018

Planning a future randomized clinical trial based on a network of relevant past trials.

Trials 2018 Jul 11;19(1):365. Epub 2018 Jul 11.

Institute of Social and Preventive Medicine (ISPM), University of Bern, Bern, Switzerland.

View Article and Find Full Text PDF
July 2018

Component network meta-analysis identifies the most effective components of psychological preparation for adults undergoing surgery under general anesthesia.

J Clin Epidemiol 2018 06 21;98:105-116. Epub 2018 Feb 21.

NIHR Complex Reviews Support Unit, Biostatistics Research Group, Department of Health Sciences, University of Leicester, Leicester, UK.

View Article and Find Full Text PDF
June 2018

Not enough I say! Expand the remit of living systematic reviews to inform future research.

Authors:
Alex J Sutton

J Clin Epidemiol 2017 11 11;91:54-55. Epub 2017 Sep 11.

Department of Health Sciences, University of Leicester, 2nd Floor (Room 214e) Adrian Bldg, Leicester LE1 7RH, UK. Electronic address:

View Article and Find Full Text PDF
November 2017

Baseline Morphine Consumption May Explain Between-Study Heterogeneity in Meta-analyses of Adjuvant Analgesics and Improve Precision and Accuracy of Effect Estimates.

Anesth Analg 2018 02;126(2):648-660

From the Department of Surgery and Anaesthesia, Division of Medical Sciences and Graduate Entry Medicine, University of Nottingham, Derby, United Kingdom.

View Article and Find Full Text PDF
February 2018

Three-dimensional evidence network plot system: covariate imbalances and effects in network meta-analysis explored using a new software tool.

J Clin Epidemiol 2017 Jun 24;86:182-195. Epub 2017 Mar 24.

Department of Health Sciences, University of Leicester, Centre for Medicine, University Road, Leicester LE1 7RH, UK.

View Article and Find Full Text PDF
June 2017

Accounting for heterogeneity in meta-analysis using a multiplicative model-an empirical study.

Res Synth Methods 2017 Mar 3;8(1):43-52. Epub 2016 Jun 3.

Department of Health Sciences, University of Leicester, Leicester, UK.

View Article and Find Full Text PDF
March 2017

Network meta-analysis of multiple outcome measures accounting for borrowing of information across outcomes.

BMC Med Res Methodol 2014 Jul 21;14:92. Epub 2014 Jul 21.

Biostatistics Group, Department of Health Sciences, University of Leicester, University Road, Leicester LE1 7RH, UK.

View Article and Find Full Text PDF
July 2014

Cost-effectiveness of interventions for increasing the possession of functioning smoke alarms in households with pre-school children: a modelling study.

BMC Public Health 2014 May 16;14:459. Epub 2014 May 16.

Department of Health Sciences, University of Leicester, 2nd Floor Adrian Building, University Road, Leicester LE1 7RH, UK.

View Article and Find Full Text PDF
May 2014

In meta-analyses of proportion studies, funnel plots were found to be an inaccurate method of assessing publication bias.

J Clin Epidemiol 2014 Aug 29;67(8):897-903. Epub 2014 Apr 29.

Department of Cardiovascular Sciences, and the NIHR Leicester Cardiovascular Biomedical Research Unit, University of Leicester, University Road, Leicester, LE1 7RD, UK.

View Article and Find Full Text PDF
August 2014

Hierarchical network meta-analysis models to address sparsity of events and differing treatment classifications with regard to adverse outcomes.

Stat Med 2014 Jun 13;33(14):2449-66. Epub 2014 Mar 13.

University of Exeter Medical School, St Luke's Campus, Magdalen Road, Exeter, EX1 2LU, U.K.

View Article and Find Full Text PDF
June 2014

Comparative clinical effectiveness of management strategies for sciatica: systematic review and network meta-analyses.

Spine J 2015 Jun 4;15(6):1461-77. Epub 2013 Oct 4.

North Wales Centre for Primary Care Research, College of Health & Behavioural Sciences, Bangor University, Gwenfro Unit 4-8, Wrexham Technology Park Wrexham, UK LL13 7YP.

View Article and Find Full Text PDF
June 2015

A multicomponent decision tool for prioritising the updating of systematic reviews.

BMJ 2013 Dec 13;347:f7191. Epub 2013 Dec 13.

Public Health, Epidemiology and Biostatistics, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK.

View Article and Find Full Text PDF
December 2013

Use of implicit and explicit bayesian methods in health technology assessment.

Int J Technol Assess Health Care 2013 Jul;29(3):336-42

Department of Health Sciences, University of Leicester, Leicester, UK.

View Article and Find Full Text PDF
July 2013

Evidence synthesis for decision making 7: a reviewer's checklist.

Med Decis Making 2013 07;33(5):679-91

School of Social and Community Medicine, University of Bristol, Bristol, UK (AEA, DMC, NJW, SD)

View Article and Find Full Text PDF
July 2013

Evidence synthesis for decision making 6: embedding evidence synthesis in probabilistic cost-effectiveness analysis.

Med Decis Making 2013 07;33(5):671-8

School of Social and Community Medicine, University of Bristol, Bristol, UK (SD, NJW, AEA)

View Article and Find Full Text PDF
July 2013

Evidence synthesis for decision making 5: the baseline natural history model.

Med Decis Making 2013 07;33(5):657-70

School of Social and Community Medicine, University of Bristol, Bristol, UK (SD, NJW, AEA)

View Article and Find Full Text PDF
July 2013

Evidence synthesis for decision making 4: inconsistency in networks of evidence based on randomized controlled trials.

Med Decis Making 2013 07;33(5):641-56

School of Social and Community Medicine, University of Bristol, Bristol, UK (SD, NJW, DMC, GL, AEA)

View Article and Find Full Text PDF
July 2013

Evidence synthesis for decision making 3: heterogeneity--subgroups, meta-regression, bias, and bias-adjustment.

Med Decis Making 2013 07;33(5):618-40

School of Social and Community Medicine, University of Bristol, Bristol, UK (SD, NJW, AEA)

View Article and Find Full Text PDF
July 2013

Evidence synthesis for decision making 1: introduction.

Med Decis Making 2013 07;33(5):597-606

School of Social and Community Medicine, University of Bristol, Bristol, UK (SD, NJW, AEA)

View Article and Find Full Text PDF
July 2013

Using meta-analysis to inform the design of subsequent studies of diagnostic test accuracy.

Res Synth Methods 2013 Jun 21;4(2):156-68. Epub 2012 Nov 21.

Biostatistics Group, Department of Health Sciences, University of Leicester, Leicester, UK.

View Article and Find Full Text PDF
June 2013

Multivariate meta-analysis of mixed outcomes: a Bayesian approach.

Stat Med 2013 Sep 30;32(22):3926-43. Epub 2013 Apr 30.

Biostatistics Research Group, Department of Health Sciences, University of Leicester, University Road, Leicester, LE1 7RH, U.K.

View Article and Find Full Text PDF
September 2013

Evidence synthesis for decision making 2: a generalized linear modeling framework for pairwise and network meta-analysis of randomized controlled trials.

Med Decis Making 2013 07 26;33(5):607-17. Epub 2012 Oct 26.

School of Social and Community Medicine, University of Bristol, Bristol, UK (SD, AEA, NJW)

View Article and Find Full Text PDF
July 2013

When is a further clinical trial justified?

BMJ 2012 Sep 13;345:e5913. Epub 2012 Sep 13.

The George Institute for Global Health, University of Sydney, PO Box M201, Missenden Road, NSW 2050, Australia.

View Article and Find Full Text PDF
September 2012

Deriving input parameters for cost-effectiveness modeling: taxonomy of data types and approaches to their statistical synthesis.

Value Health 2012 Jul-Aug;15(5):639-49. Epub 2012 May 23.

Centre for Health Economics, University of York, York, UK.

View Article and Find Full Text PDF
October 2012

Planning future studies based on the conditional power of a meta-analysis.

Stat Med 2013 Jan 11;32(1):11-24. Epub 2012 Jul 11.

MRC Biostatistics Unit, Cambridge, U.K.

View Article and Find Full Text PDF
January 2013

Mixed treatment comparisons using aggregate and individual participant level data.

Stat Med 2012 Dec 5;31(28):3516-36. Epub 2012 Jul 5.

Centre for Health Economics, University of York, York, UK.

View Article and Find Full Text PDF
December 2012

Predicting infectious complications in neutropenic children and young people with cancer (IPD protocol).

Syst Rev 2012 Feb 9;1. Epub 2012 Feb 9.

Centre for Reviews and Dissemination, Alcuin College, University of York, York, YO10 5DD, UK.

View Article and Find Full Text PDF
February 2012

Systematic review of methods used in meta-analyses where a primary outcome is an adverse or unintended event.

BMC Med Res Methodol 2012 May 3;12:64. Epub 2012 May 3.

Peninsula College of Medicine and Dentistry, St Luke's Campus, University of Exeter, Exeter, UK.

View Article and Find Full Text PDF
May 2012

A generalized weighting regression-derived meta-analysis estimator robust to small-study effects and heterogeneity.

Stat Med 2012 Jun 21;31(14):1407-17. Epub 2012 Feb 21.

Department of Evaluation of Innovation and New Technologies, Fundació Clínic per a la Recerca Biomédica, Barcelona 08036, Spain.

View Article and Find Full Text PDF
June 2012

Network meta-analysis to evaluate the effectiveness of interventions to increase the uptake of smoke alarms.

Epidemiol Rev 2012 29;34:32-45. Epub 2011 Nov 29.

Centre for Biostatistics and Genetic Epidemiology, Department of Health Sciences, University of Leicester, 22-28 Princess Road West, Leicester LE1 6TP, United Kingdom.

View Article and Find Full Text PDF
May 2012

Surgical versus nonsurgical treatment of acute minimally displaced and undisplaced scaphoid waist fractures: pairwise and network meta-analyses of randomized controlled trials.

J Hand Surg Am 2011 Nov;36(11):1759-1768.e1

Division of Orthopaedic Surgery and Department of Health Sciences, University of Leicester, Leicester, United Kingdom.

View Article and Find Full Text PDF
November 2011

Surrogates, meta-analysis and cost-effectiveness modelling: a combined analytic approach.

Health Econ 2012 Jun 28;21(6):742-56. Epub 2011 Jul 28.

Centre for Health Economics, University of York, Heslington,York, UK.

View Article and Find Full Text PDF
June 2012

Glycaemic control in type 1 diabetes during real time continuous glucose monitoring compared with self monitoring of blood glucose: meta-analysis of randomised controlled trials using individual patient data.

BMJ 2011 Jul 7;343:d3805. Epub 2011 Jul 7.

Diabetes Research Group, Division of Diabetes and Nutritional Sciences, King's College London School of Medicine, Guy's Hospital, London SE1 1UL, UK.

View Article and Find Full Text PDF
July 2011

Adjusting for publication biases across similar interventions performed well when compared with gold standard data.

J Clin Epidemiol 2011 Nov 6;64(11):1230-41. Epub 2011 May 6.

Department of Evaluation of Innovation and New Technologies, Fundació Clínic, C/ Urgell 216, baixos, Barcelona 08036, Spain.

View Article and Find Full Text PDF
November 2011

'Cross hairs' plots for diagnostic meta-analysis.

Res Synth Methods 2010 Jul 11;1(3-4):308-15. Epub 2011 Mar 11.

Centre for Reviews and Dissemination, University of York, York, YO10 5DD, U.K.

View Article and Find Full Text PDF
July 2010

The effectiveness of anti-TNF-alpha therapies when used sequentially in rheumatoid arthritis patients: a systematic review and meta-analysis.

Rheumatology (Oxford) 2010 Dec 21;49(12):2313-21. Epub 2010 Jun 21.

Department of Health Sciences, University of Leicester, Leicester, UK.

View Article and Find Full Text PDF
December 2010

Extent of publication bias in different categories of research cohorts: a meta-analysis of empirical studies.

BMC Med Res Methodol 2009 Nov 26;9:79. Epub 2009 Nov 26.

School of Medicine, Health Policy and Practice, University of East Anglia, Earlham Road, Norwich NR4 7TJ, UK.

View Article and Find Full Text PDF
November 2009

Interspecies extrapolation in environmental exposure standard setting: A Bayesian synthesis approach.

Regul Toxicol Pharmacol 2009 Apr 10;53(3):217-25. Epub 2009 Feb 10.

Department of Health Sciences, Adrian Building, University of Leicester, Leicester, LE1 7RH, UK.

View Article and Find Full Text PDF
April 2009

Ranking antidepressants.

Lancet 2009 May;373(9677):1760; author reply 1761-2

View Article and Find Full Text PDF
May 2009

An encouraging assessment of methods to inform priorities for updating systematic reviews.

J Clin Epidemiol 2009 Mar 10;62(3):241-51. Epub 2008 Sep 10.

Department of Health Sciences, University of Leicester, Leicester, UK.

View Article and Find Full Text PDF
March 2009

Preventing childhood falls at home: meta-analysis and meta-regression.

Am J Prev Med 2008 Oct;35(4):370-379

Division of Primary Care, School of Nursing, University of Nottingham, Hucknall Primary Care Trust, Hucknall Health Centre, Nottingham, England, UK.

View Article and Find Full Text PDF
October 2008

Contour-enhanced meta-analysis funnel plots help distinguish publication bias from other causes of asymmetry.

J Clin Epidemiol 2008 Oct 6;61(10):991-6. Epub 2008 Jun 6.

Department of Health Sciences, University of Leicester, Leicester, UK.

View Article and Find Full Text PDF
October 2008

Different strategies for screening and prevention of type 2 diabetes in adults: cost effectiveness analysis.

BMJ 2008 May 21;336(7654):1180-5. Epub 2008 Apr 21.

Centre for Biostatistics and Genetic Epidemiology, Department of Health Sciences, University of Leicester, Leicester LE1 7RH.

View Article and Find Full Text PDF
May 2008

Randomized trials with concurrent economic evaluations reported unrepresentatively large clinical effect sizes.

J Clin Epidemiol 2007 Aug 26;60(8):781-6. Epub 2007 Mar 26.

Department of Health Sciences, University of York, York YO10 5DD, UK.

View Article and Find Full Text PDF
August 2007

Estimating the cost-effectiveness of an intervention in a clinical trial when partial cost information is available: a Bayesian approach.

Health Econ 2008 Jan;17(1):67-81

Centre for Biostatistics and Genetic Epidemiology, Department of Health Sciences, University of Leicester, Leicester, UK.

View Article and Find Full Text PDF
January 2008

Performance of the trim and fill method in the presence of publication bias and between-study heterogeneity.

Stat Med 2007 Nov;26(25):4544-62

Department of Health Sciences, University of Leicester, Leicester LE1 7RH, U.K.

View Article and Find Full Text PDF
November 2007

Pharmacological and lifestyle interventions to prevent or delay type 2 diabetes in people with impaired glucose tolerance: systematic review and meta-analysis.

BMJ 2007 Feb 19;334(7588):299. Epub 2007 Jan 19.

Centre for Biostatistics and Genetic Epidemiology, Department of Health Sciences, University of Leicester, Leicester LE1 7RH.

View Article and Find Full Text PDF
February 2007

Collaborative care for depression: a cumulative meta-analysis and review of longer-term outcomes.

Arch Intern Med 2006 Nov;166(21):2314-21

Department of Health Sciences, University of York, York, England.

View Article and Find Full Text PDF
November 2006