Alex Frase

Alex Frase

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Alex Frase

Alex Frase

Publications by authors named "Alex Frase"

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PHENOME-WIDE INTERACTION STUDY (PheWIS) IN AIDS CLINICAL TRIALS GROUP DATA (ACTG).

Pac Symp Biocomput 2016 ;21:57-68

Center for System Genomics, The Pennsylvania State University, University Park, PA 16802, USA;

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4722952PMC
October 2016

INTEGRATING CLINICAL LABORATORY MEASURES AND ICD-9 CODE DIAGNOSES IN PHENOME-WIDE ASSOCIATION STUDIES.

Pac Symp Biocomput 2016 ;21:168-79

Biomedical and Translational Informatics, Geisinger Health System, Danville, PA, USA3Center for Systems Genomics, The Pennsylvania State University, University Park, PA, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4718547PMC
October 2016

BIOFILTER AS A FUNCTIONAL ANNOTATION PIPELINE FOR COMMON AND RARE COPY NUMBER BURDEN.

Pac Symp Biocomput 2016 ;21:357-68

Center for Systems Genomics, Department of Biochemistry and Molecular Biology, Pennsylvania State University, University Park, Pennsylvania, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4722964PMC
October 2016

A biologically informed method for detecting rare variant associations.

BioData Min 2016 30;9(1):27. Epub 2016 Aug 30.

Department of Biochemistry and Molecular Biology, Center for Systems Genomics, The Pennsylvania State University, University Park, PA 16802 USA.

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http://dx.doi.org/10.1186/s13040-016-0107-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5006419PMC
September 2016

Pathway analysis by randomization incorporating structure-PARIS: an update.

Bioinformatics 2016 08 7;32(15):2361-3. Epub 2016 Mar 7.

Department of Epidemiology and Biostatistics, Case Western Reserve University, Cleveland, OH, USA Institute for Computational Biology, Case Western Reserve University, Cleveland, OH, USA.

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http://dx.doi.org/10.1093/bioinformatics/btw130DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4965631PMC
August 2016

Knowledge-driven genomic interactions: an application in ovarian cancer.

BioData Min 2014 9;7:20. Epub 2014 Sep 9.

Department of Biochemistry and Molecular Biology, Center for Systems Genomics, Pennsylvania State University, University Park, Pennsylvania, USA.

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http://dx.doi.org/10.1186/1756-0381-7-20DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4161273PMC
September 2014

Low frequency variants, collapsed based on biological knowledge, uncover complexity of population stratification in 1000 genomes project data.

PLoS Genet 2013 26;9(12):e1003959. Epub 2013 Dec 26.

Center for Systems Genomics, Department of Biochemistry and Molecular Biology, The Pennsylvania State University, Eberly College of Science, The Huck Institutes of the Life Sciences, University Park, Pennsylvania, United States of America.

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http://dx.doi.org/10.1371/journal.pgen.1003959DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3873241PMC
August 2014

ATHENA: the analysis tool for heritable and environmental network associations.

Bioinformatics 2014 Mar 21;30(5):698-705. Epub 2013 Oct 21.

Inherited Disease Research Branch, National Human Genome Research Institute, National Institutes of Health, Baltimore, MD, USA and Department of Biochemistry and Molecular Biology, Center for Systems Genomics, Pennsylvania State University, University Park, PA, USA.

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http://dx.doi.org/10.1093/bioinformatics/btt572DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3933870PMC
March 2014

Using BioBin to explore rare variant population stratification.

Pac Symp Biocomput 2013 :332-43

Center for Human Genetics Research, Vanderbilt University, 519 Light Hall, Nashville, TN 37232, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3638724PMC
December 2013

Genomic analyses with biofilter 2.0: knowledge driven filtering, annotation, and model development.

BioData Min 2013 Dec 30;6(1):25. Epub 2013 Dec 30.

Center for Systems Genomics, Department of Biochemistry and Molecular Biology, The Pennsylvania State University, Eberly College of Science, The Huck Institutes of the Life Sciences, University Park, Pennsylvania, PA, USA.

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http://dx.doi.org/10.1186/1756-0381-6-25DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3917600PMC
December 2013

BioBin: a bioinformatics tool for automating the binning of rare variants using publicly available biological knowledge.

BMC Med Genomics 2013 7;6 Suppl 2:S6. Epub 2013 May 7.

Center for Human Genetics Research, Vanderbilt University, Nashville, TN 37232, USA.

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http://dx.doi.org/10.1186/1755-8794-6-S2-S6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3654874PMC
October 2013