Alex C Spyropoulos

Alex C Spyropoulos

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Alex C Spyropoulos

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Comparison of international societal guidelines for the diagnosis of suspected pulmonary embolism during pregnancy.

Lancet Haematol 2020 Mar;7(3):e247-e258

Department of Medicine, Northwell Health, Manhasset, NY, USA; Center for Health Innovations and Outcomes Research, Feinstein Institutes for Medical Research and Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Manhasset, NY, USA.

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http://dx.doi.org/10.1016/S2352-3026(19)30250-9DOI Listing
March 2020

Heparin Bridging Therapy for Patients on Chronic Oral Anticoagulants in Periprocedural Settings.

Semin Thromb Hemost 2020 Feb 12;46(1):26-31. Epub 2019 Dec 12.

The Feinstein Institute for Medical Research, Manhasset, New York.

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http://dx.doi.org/10.1055/s-0039-1696945DOI Listing
February 2020

Does telehealth improve anticoagulation management in patient service centers (PSC)? A pilot project.

J Thromb Thrombolysis 2020 Feb;49(2):316-320

Northwell Health At Lenox Hill Hospital, New York, NY, USA.

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http://dx.doi.org/10.1007/s11239-019-02031-4DOI Listing
February 2020

Epidural Catheter Use and Further Issues in Patients With Atrial Fibrillation Receiving a Direct Oral Anticoagulant-Reply.

JAMA Intern Med 2020 Feb;180(2):333-334

Department of Medicine, McMaster University, Hamilton, Ontario, Canada.

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http://dx.doi.org/10.1001/jamainternmed.2019.5851DOI Listing
February 2020

External Validation of a Venous Thromboembolic Risk Score for Cancer Outpatients with Solid Tumors: The COMPASS-CAT Venous Thromboembolism Risk Assessment Model.

Oncologist 2020 Feb 4. Epub 2020 Feb 4.

Center for Health Innovations and Outcomes Research, Feinstein Institute for Medical Research, Manhasset, New York, USA.

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http://dx.doi.org/10.1634/theoncologist.2019-0482DOI Listing
February 2020

Extended vs. standard-duration thromboprophylaxis in acutely ill medical patients: A systematic review and meta-analysis.

Thromb Res 2019 Dec 31;184:58-61. Epub 2019 Oct 31.

Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States of America; Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States of America.

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http://dx.doi.org/10.1016/j.thromres.2019.10.027DOI Listing
December 2019

Proportion of US Hospitalized Medically Ill Patients Who May Qualify for Extended Thromboprophylaxis.

Clin Appl Thromb Hemost 2019 Jan-Dec;25:1076029619850897

1 Department of Pharmacy Practice, University of Connecticut School of Pharmacy, Storrs, CT, USA.

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http://dx.doi.org/10.1177/1076029619850897DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6714926PMC
November 2019

Assessment of warfarin algorithms for hospitalized adults: searching for a safe dosing strategy.

J Thromb Thrombolysis 2019 Nov;48(4):570-579

Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Northwell Health, Manhasset, NY, 11030, USA.

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http://dx.doi.org/10.1007/s11239-019-01902-0DOI Listing
November 2019

Quality metrics of warfarin initiation in hospitalized older adults.

J Thromb Thrombolysis 2019 Oct;48(3):459-465

Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Northwell Health, Manhasset, NY, 11030, USA.

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http://dx.doi.org/10.1007/s11239-019-01905-xDOI Listing
October 2019

Rivaroxaban versus warfarin treatment among morbidly obese patients with venous thromboembolism: Comparative effectiveness, safety, and costs.

Thromb Res 2019 Oct 22;182:159-166. Epub 2019 Aug 22.

Duke Clinical Research Institute, Duke University School of Medicine, 2400 Pratt St Ste 7009, Durham, NC 27705, USA. Electronic address:

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http://dx.doi.org/10.1016/j.thromres.2019.08.021DOI Listing
October 2019

Comparative effectiveness, safety, and costs of rivaroxaban and warfarin among morbidly obese patients with atrial fibrillation.

Am Heart J 2019 06 20;212:113-119. Epub 2019 Feb 20.

Department of Medicine, Anticoagulation and Clinical Thrombosis Services, Northwell Health System, The Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Manhasset, NY.

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http://dx.doi.org/10.1016/j.ahj.2019.02.001DOI Listing
June 2019

Thromboprophylaxis after Hospitalization for Medical Illness.

N Engl J Med 2018 12;379(23):2280

University of Oklahoma Health Sciences Center, Oklahoma City, OK

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http://dx.doi.org/10.1056/NEJMc1813803DOI Listing
December 2018

Treatment of Venous Thromboembolism in Elite Athletes: A Suggested Approach to Individualized Anticoagulation.

Semin Thromb Hemost 2018 Nov 8;44(8):813-822. Epub 2018 Oct 8.

Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington, District of Columbia.

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http://www.thieme-connect.de/DOI/DOI?10.1055/s-0038-1673690
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http://dx.doi.org/10.1055/s-0038-1673690DOI Listing
November 2018

Periprocedural Outcomes of Direct Oral Anticoagulants Versus Warfarin in Nonvalvular Atrial Fibrillation.

Circulation 2018 10;138(14):1402-1411

Center for Health Innovations and Outcomes Research, Feinstein Institute for Medical Research, Manhasset, NY (M.Z., A.C.S.).

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http://dx.doi.org/10.1161/CIRCULATIONAHA.117.031457DOI Listing
October 2018

Rivaroxaban for Thromboprophylaxis after Hospitalization for Medical Illness.

N Engl J Med 2018 Sep 26;379(12):1118-1127. Epub 2018 Aug 26.

From the Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Feinstein Institute for Medical Research, and the Department of Medicine, Anticoagulation and Clinical Thrombosis Services, Northwell Health at Lenox Hill Hospital (A.C.S.), and the Cardiovascular Institute, Mount Sinai Medical Center (J.L.H.) - all in New York; the Department of Medicine and Surgery, University of Insubria, Varese, Italy (W.A.); the Stanford Stroke Center, Stanford University Medical Center, Stanford (G.W.A.), and the University of California at Davis, Sacramento (G.A.M.) - both in California; the Department of Medicine, Intermountain Medical Center, and Department of Medicine, University of Utah, Salt Lake City (C.G.E.); Division of Cardiology, University of Colorado School of Medicine, and CPC Clinical Research, Aurora (W.R.H.); Département Hospitalo-Universitaire FIRE (Fibrose Inflammation Remodelage), University Paris Diderot, Assistance Publique-Hôpitaux de Paris, and INSERM Unité 1148, Paris (P.G.S.); Imperial College, Royal Brompton Hospital, London (P.G.S.); McMaster University and the Thrombosis and Atherosclerosis Research Institute - both in Hamilton, ON, Canada (J.I.W.); Janssen Research and Development, Raritan (E.S., E.S.B.), and the Thrombosis and Hematology Therapeutic Area, Clinical Development, Pharmaceuticals, Bayer U.S., Whippany (T.E.S.) - both in New Jersey; and the College of Public Health, University of Oklahoma Health Sciences Center, Oklahoma City (G.E.R.).

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http://dx.doi.org/10.1056/NEJMoa1805090DOI Listing
September 2018

Warfarin Quality Metrics for Hospitalized Older Adults.

TH Open 2018 Jul 18;2(3):e242-e249. Epub 2018 Jul 18.

Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Northwell Health, Manhasset, New York, United States.

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http://dx.doi.org/10.1055/s-0038-1667138DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6524880PMC
July 2018

Postthrombotic Syndrome in Patients Treated With Rivaroxaban or Warfarin for Venous Thromboembolism.

Clin Appl Thromb Hemost 2018 May 8;24(4):575-582. Epub 2018 Mar 8.

6 Department of Medicine, Anticoagulation and Clinical Thrombosis Services, Northwell Health System, Hofstra Northwell School of Medicine, Manhasset, NY, USA.

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http://journals.sagepub.com/doi/10.1177/1076029618758955
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http://dx.doi.org/10.1177/1076029618758955DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6714693PMC
May 2018

Extended thromboprophylaxis in the acutely ill medical patient after hospitalization - a paradigm shift in post-discharge thromboprophylaxis.

Hosp Pract (1995) 2018 Feb 30;46(1):5-15. Epub 2017 Nov 30.

c Hofstra Northwell School of Medicine, Department of Medicine , Northwell Health System at Lenox Hill Hospital , New York , NY , USA.

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http://dx.doi.org/10.1080/21548331.2018.1410053DOI Listing
February 2018

Direct oral anticoagulants in the treatment of pulmonary embolism.

Curr Med Res Opin 2018 01 1;34(1):131-140. Epub 2017 Sep 1.

b Hofstra Northwell School of Medicine, Department of Medicine , Anticoagulation and Clinical Thrombosis Services, Northwell Health System, Lenox Hill Hospital , New York , NY , USA.

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http://dx.doi.org/10.1080/03007995.2017.1364227DOI Listing
January 2018

A Predictive Score for Thrombosis Associated with Breast, Colorectal, Lung, or Ovarian Cancer: The Prospective COMPASS-Cancer-Associated Thrombosis Study.

Oncologist 2017 10 26;22(10):1222-1231. Epub 2017 May 26.

Cancer Biology and Therapeutics, INSERM U938, Institut Universitaire de Cancérologie (IUC), Faculté de Médecine Pierre et Marie Curie, Université Pierre et Marie Curie (UPMC), Sorbonne Universités, Paris, France.

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http://dx.doi.org/10.1634/theoncologist.2016-0414DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5634762PMC
October 2017

New paradigms in venous thromboprophylaxis of medically ill patients.

Thromb Haemost 2017 08 22;117(9):1662-1670. Epub 2017 Jun 22.

Alex C. Spyropoulos, MD, FACP, FCCP, FRCPC, Professor of Medicine - Hofstra Northwell School of Medicine, Professor - The Merinoff Center for Patient-Oriented Research, The Feinstein Institute for Medical Research, System Director - Anticoagulation and Clinical Thrombosis Services, Northwell Health at Lenox Hill Hospital, 130 E 77th St, New York, NY 10075, USA, Tel.: +1 212 434 6776, Fax: +1 212 434 6781, E-mail:

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http://dx.doi.org/10.1160/TH17-03-0168DOI Listing
August 2017

The IMPROVEDD VTE Risk Score: Incorporation of D-Dimer into the IMPROVE Score to Improve Venous Thromboembolism Risk Stratification.

TH Open 2017 Jun 28;1(1):e56-e65. Epub 2017 Jun 28.

Cardiovascular Division, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, United States.

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http://dx.doi.org/10.1055/s-0037-1603929DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6524839PMC
June 2017

Re-Initiation of Dabigatran and Direct Factor Xa Antagonists After a Major Bleed.

Am J Med 2016 Nov 26;129(11S):S54-S63. Epub 2016 Aug 26.

Department of Medicine, Anticoagulation and Clinical Thrombosis Services, Hofstra North Shore-LIJ School of Medicine, North Shore-LIJ Health System, Manhasset, NY.

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http://dx.doi.org/10.1016/j.amjmed.2016.06.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5568864PMC
November 2016

Re-initiation of dabigatran and direct factor Xa antagonists after a major bleed.

Am J Emerg Med 2016 Nov 28;34(11S):19-25. Epub 2016 Sep 28.

Department of Medicine, Anticoagulation and Clinical Thrombosis Services, Hofstra North Shore-LIJ School of Medicine, North Shore-LIJ Health System, Manhasset, NY.

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http://dx.doi.org/10.1016/j.ajem.2016.09.049DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5678962PMC
November 2016

Perioperative Management of the Direct Oral Anticoagulants: A Case-Based Review.

Hematol Oncol Clin North Am 2016 10;30(5):1073-84

Division of Hematology and Thromboembolism, Department of Medicine, McMaster University, St. Joseph's Hospital, 50 Charlton Avenue East, Room F-544, Hamilton, ON L8N 4A6, Canada.

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http://dx.doi.org/10.1016/j.hoc.2016.05.005DOI Listing
October 2016

The BRIDGE trial: What the hospitalist should know.

J Hosp Med 2016 09 21;11(9):652-7. Epub 2016 Apr 21.

Department of Medicine, Anticoagulation and Clinical Thrombosis Services, Hofstra-Northwell Health School of Medicine, Northwell Health at Lenox Hill Hospital, New York, New York.

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http://dx.doi.org/10.1002/jhm.2594DOI Listing
September 2016

Venous thromboembolism following hematopoietic stem cell transplantation-a systematic review and meta-analysis.

Ann Hematol 2016 Sep 22;95(9):1457-64. Epub 2016 Apr 22.

Mayo Clinic Transplant Center, Blood and Marrow Transplant Program, Mayo Clinic, Rochester, MN, USA.

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http://dx.doi.org/10.1007/s00277-016-2673-3DOI Listing
September 2016

Validation of Risk Assessment Models of Venous Thromboembolism in Hospitalized Medical Patients.

Am J Med 2016 09 21;129(9):1001.e9-1001.e18. Epub 2016 Apr 21.

The Michigan Hospital Medicine Safety Consortium Data Coordinating Center, Ann Arbor; Department of Internal Medicine, University of Michigan Medical School, Ann Arbor.

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http://dx.doi.org/10.1016/j.amjmed.2016.03.031DOI Listing
September 2016

Cost-of-illness model for venous thromboembolism.

Thromb Res 2016 Sep 23;145:130-2. Epub 2016 Jun 23.

Department of Medicine, Anticoagulation and Clinical Thrombosis Services, Northwell Health System, Hofstra Northwell School of Medicine, Manhasset, USA. Electronic address:

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http://dx.doi.org/10.1016/j.thromres.2016.06.022DOI Listing
September 2016

External validation of the IMPROVE Bleeding Risk Assessment Model in medical patients.

Thromb Haemost 2016 08 16;116(3):530-6. Epub 2016 Jun 16.

Alex C. Spyropoulos, MD, FACP, FCCP, FRCPC, Hofstra, North Shore - LIJ School of Medicine, Lenox Hill Hospital, 130 E 77th St, New York, NY 10075, USA, Tel.: +1 212 434 6776, Fax: +1 212 434 6781, E-mail:

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http://dx.doi.org/10.1160/TH16-01-0003DOI Listing
August 2016

Bivariate evaluation of thromboembolism and bleeding in clinical trials of anticoagulants in patients with atrial fibrillation.

Thromb Haemost 2016 08 23;116(3):544-53. Epub 2016 Jun 23.

John M. Kittelson, Ph.D., Historic Building 500, Box B119, University of Colorado Anschutz Medical Campus, 13001 East 17th Place, Aurora, CO 80045, USA, Tel.: +1 303 724 4364, E-mail:

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http://dx.doi.org/10.1160/TH15-12-1000DOI Listing
August 2016

The MARINER trial of rivaroxaban after hospital discharge for medical patients at high risk of VTE. Design, rationale, and clinical implications.

Thromb Haemost 2016 06 4;115(6):1240-8. Epub 2016 Feb 4.

Gary E. Raskob, PhD, Dean, College of Public Health and Regents' Professor, Epidemiology and Medicine, University of Oklahoma Health Sciences Center, College of Public Health, 801 NE 13th Street, Oklahoma City, OK 73104, USA, Tel.: +1 405 271 2232, Fax: +1 405 271 3039, E-mail:

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http://dx.doi.org/10.1160/TH15-09-0756DOI Listing
June 2016

European Union-28: An annualised cost-of-illness model for venous thromboembolism.

Thromb Haemost 2016 Apr 26;115(4):800-8. Epub 2015 Nov 26.

Charles E. Mahan, PharmD, Pharmacist Clinician, Presbyterian Healthcare Services, Clinical Assistant Professor of Pharmacy, University of New Mexico, 1100 Central Ave. SE, Albuquerque, NM 87106, USA, Tel.: +1 505 841 1545, Fax: +1 505 841 1802, E-mail:

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http://dx.doi.org/10.1160/TH15-08-0670DOI Listing
April 2016

Urgent surgery or procedures in patients taking dabigatran or warfarin: Analysis of perioperative outcomes from the RE-LY trial.

Thromb Res 2016 Mar 9;139:77-81. Epub 2016 Jan 9.

Department of Medicine, McMaster University, Hamilton, Canada; Population Health Research Institute, McMaster University, Hamilton, Canada.

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http://dx.doi.org/10.1016/j.thromres.2016.01.004DOI Listing
March 2016

All-cause mortality and use of antithrombotics within 90 days of discharge in acutely ill medical patients.

Thromb Haemost 2015 Oct 23;114(4):685-94. Epub 2015 Jul 23.

Alex C Spyropoulos, MD, FACP, FCCP, FRCPC, Professor of Medicine, Hofstra North Shore-LIJ School of Medicine, 130 E &77th St 10075, Manhasset, NY, USA, Tel.: +1 212 434 6776, Fax: +1 212 434 6781, E-mail:

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http://dx.doi.org/10.1160/TH15-02-0108DOI Listing
October 2015

Perioperative Bridging Anticoagulation in Patients with Atrial Fibrillation.

N Engl J Med 2015 Aug 22;373(9):823-33. Epub 2015 Jun 22.

From St. Joseph's Healthcare Hamilton (J.D.D.) and the Department of Medicine (J.D.D.) and Hamilton Health Science Center (S.S., A.G.G.T.), McMaster University, Hamilton, ON, Canada; Hofstra North Shore-Long Island Jewish School of Medicine, Manhasset (A.C.S.), and Mount Sinai Medical Center, New York (A.S.D.) - both in New York; Hurley Medical Center, Flint, MI (S.K.); University of Cincinnati College of Medicine, Cincinnati (R.C.B.); NorthShore University HealthSystem, Evanston (J.A.C.), and Rush University Medical Center, Chicago (A.K.J.) - both in Illinois; University of Washington Medical Center, Seattle (D.A.G.); Veterans Affairs Loma Linda Healthcare System, Loma Linda, CA (A.J.); and Duke Clinical Research Institute (D.F.K., V.H.) and Department of Medicine (T.L.O.), Duke University Medical Center, Durham, NC.

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http://dx.doi.org/10.1056/NEJMoa1501035DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4931686PMC
August 2015

Management of anticoagulants in the periprocedural period for patients with cancer.

J Natl Compr Canc Netw 2014 Dec;12(12):1713-20

From North Shore-LIJ Health System at Lenox Hill Hospital and Hofstra North Shore-LIJ School of Medicine, New York, New York. From North Shore-LIJ Health System at Lenox Hill Hospital and Hofstra North Shore-LIJ School of Medicine, New York, New York.

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http://dx.doi.org/10.6004/jnccn.2014.0173DOI Listing
December 2014

Direct oral anticoagulants: new drugs and new concepts.

JACC Cardiovasc Interv 2014 Dec;7(12):1333-51

McMaster University, Hamilton, Ontario, Canada.

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http://dx.doi.org/10.1016/j.jcin.2014.06.014DOI Listing
December 2014

The potential of target-specific oral anticoagulants for the acute and long-term treatment of venous thromboembolism.

Curr Med Res Opin 2014 Nov 19;30(11):2179-90. Epub 2014 Aug 19.

School of Medicine, University of Rochester , Rochester, NY , USA.

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http://dx.doi.org/10.1185/03007995.2014.951425DOI Listing
November 2014

External validation of the risk assessment model of the International Medical Prevention Registry on Venous Thromboembolism (IMPROVE) for medical patients in a tertiary health system.

J Am Heart Assoc 2014 Nov 17;3(6):e001152. Epub 2014 Nov 17.

Department of Medicine, Hofstra North Shore LIJ School of Medicine, Manhasset, NY (D.R., M.A., L.M.C., T.M.G., A.C.S.).

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http://dx.doi.org/10.1161/JAHA.114.001152DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4338701PMC
November 2014

External validation of a risk assessment model for venous thromboembolism in the hospitalised acutely-ill medical patient (VTE-VALOURR).

Thromb Haemost 2014 Oct 3;112(4):692-9. Epub 2014 Jul 3.

Alex C Spyropoulos, MD, FACP, FCCP, FRCPC, Director - Anticoagulation Services and Clinical Thrombosis, North Shore-LIJ Health System at Lenox Hill Hospital, Professor of Medicine, Hofstra North Shore-LIJ School of Medicine, Manhasset, New York, USA, Tel.: +1 212 434 6776, Fax: +1 212 434 6781, E-mail:

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http://dx.doi.org/10.1160/TH14-03-0239DOI Listing
October 2014

Venous thromboembolism risk in patients with inflammatory bowel disease: defining the benefits of pharmacologic prophylaxis.

Clin Gastroenterol Hepatol 2014 Sep 1;12(9):1577. Epub 2014 Apr 1.

Anticoagulation and Clinical Thrombosis Services, North Shore-LIJ Health System at Lenox Hill Hospital, New York, New York.

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https://linkinghub.elsevier.com/retrieve/pii/S15423565140047
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http://dx.doi.org/10.1016/j.cgh.2014.03.025DOI Listing
September 2014

Treatment and long-term management of venous thromboembolism.

Clin Lab Med 2014 Sep 21;34(3):519-36. Epub 2014 Jul 21.

Department of Medicine, Lenox Hill Hospital, NSLIJHS, 130 East 77th Street, 5th Floor, Achilles Building, New York, NY 10075, USA.

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http://dx.doi.org/10.1016/j.cll.2014.06.011DOI Listing
September 2014

Predicting the risk of venous thromboembolism in patients hospitalized with heart failure.

Circulation 2014 Jul 26;130(5):410-8. Epub 2014 Jun 26.

From Université Paris Diderot, PRES Sorbonne Paris Cité and Department of Anesthesiology and Critical Care Medicine, Saint Louis Lariboisière University Hospitals, U942 Inserm, Paris, France (A.M.); Bayer HealthCare Pharmaceuticals Inc, Montville, NJ (T.E.S., Y.D.S.); Academic Medical Center, Amsterdam, The Netherlands (H.R.B.); Janssen Research & Development LLC, Raritan, NJ (L.H.); People's Hospital of Peking University, Beijing, China (D.H.); Foothills Hospital, Calgary, Alberta, Canada (R.H.); Thomas Jefferson Medical Center, Philadelphia, PA (G.M.); Dresden-Friedrichstadt Hospital, Dresden, Germany (S.W.S.); Hofstra North Shore-LIJ School of Medicine, Manhasset, NY (A.C.S.); Duke University Medical Center, Durham, NC (V.F.T.); and King's College Hospital, London, UK (A.T.C.).

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http://dx.doi.org/10.1161/CIRCULATIONAHA.113.003126DOI Listing
July 2014

Outcomes of temporary interruption of rivaroxaban compared with warfarin in patients with nonvalvular atrial fibrillation: results from the rivaroxaban once daily, oral, direct factor Xa inhibition compared with vitamin K antagonism for prevention of stroke and embolism trial in atrial fibrillation (ROCKET AF).

Circulation 2014 May 19;129(18):1850-9. Epub 2014 Feb 19.

Division of Cardiovascular Medicine, Duke University Medical Center, Duke Clinical Research Institute, Durham, NC (M.W.S., M.R.P., J.P.P., A.S.H., Y.L., R.M.C., R.C.B.); Department of Medicine, Division of Hematology and Thromboembolism, McMaster University, Hamilton, Ontario, Canada (J.D.D.); Department of Medicine, Division of Hematology, Hofstra North Shore/LIJ School of Medicine, Lenox Hill Hospital, New York, NY (A.C.S.); School of Medicine and Pharmacology, University of Western Australia, Perth, Western Australia, Australia (G.J.H.); Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA (D.E.S.); Johnson & Johnson Pharmaceutical Research and Development, Raritan, NJ (C.C.N.); Department of Medicine, Stanford University Medical Center, Palo Alto, CA (K.W.M.); and Department of Medicine, University of Edinburgh and Royal Infirmary of Edinburgh, Edinburgh, United Kingdom (K.A.A.F.).

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http://dx.doi.org/10.1161/CIRCULATIONAHA.113.005754DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4206548PMC
May 2014

Thromboprophylaxis patterns, risk factors, and outcomes of care in the medically ill patient population.

Thromb Res 2013 Nov 28;132(5):520-6. Epub 2013 Aug 28.

Presbyterian Healthcare Services, University of New Mexico, Albuquerque, NM, USA.

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http://dx.doi.org/10.1016/j.thromres.2013.08.013DOI Listing
November 2013

Response.

Chest 2013 Oct;144(4):1424-1426

Division of Hematology and Thromboembolism, Department of Medicine, McMaster University, Hamilton, ON, Canada.

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http://dx.doi.org/10.1378/chest.13-1728DOI Listing
October 2013

A new paradigm shift in antithrombotic therapy.

Front Pharmacol 2013 Oct 21;4:133. Epub 2013 Oct 21.

NSLIJ Lenox Hill Hospital, Internal Medicine New York, NY, USA ; Hofstra, North Shore/LIJ School of Medicine Manhasset, New York, NY, USA.

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http://dx.doi.org/10.3389/fphar.2013.00133DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3800773PMC
October 2013

Antithrombotic medication use and bleeding risk in medically ill patients after hospitalization.

Clin Appl Thromb Hemost 2013 Sep 15;19(5):504-12. Epub 2013 Jan 15.

1Department of Outcomes Research, New Mexico Heart Institute, Albuquerque, NM, USA.

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http://dx.doi.org/10.1177/1076029612470967DOI Listing
September 2013

Antithrombotic therapy and invasive procedures.

N Engl J Med 2013 09;369(11):1078

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http://dx.doi.org/10.1056/NEJMc1308259DOI Listing
September 2013

Practical issues, limitations, and periprocedural management of the NOAC's.

J Thromb Thrombolysis 2013 Aug;36(2):212-22

Division of Hematology/Oncology, Department of Medicine, James P Wilmot Cancer Center, University of Rochester Medical Center, 601 Elmwood Ave, Rochester, NY 14642, USA.

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http://dx.doi.org/10.1007/s11239-013-0911-2DOI Listing
August 2013

Identifying, monitoring and reducing preventable major bleeds in the hospital setting.

J Thromb Thrombolysis 2013 Jul;36(1):7-13

New Mexico Heart Institute, University of New Mexico, 502 Elm Street NE, Albuquerque, NM 87102, USA.

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http://dx.doi.org/10.1007/s11239-012-0819-2DOI Listing
July 2013

Venous thromboembolism management: where do novel anticoagulants fit?

Curr Med Res Opin 2013 Jul 28;29(7):783-90. Epub 2013 May 28.

North Shore/LIJ Health System at Lenox Hill Hospital, Hofstra-North Shore/LIJ School of Medicine, NY, NY, USA.

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http://dx.doi.org/10.1185/03007995.2013.803462DOI Listing
July 2013

Treatment of bleeding complications when using oral anticoagulants for prevention of strokes.

Curr Treat Options Cardiovasc Med 2013 Jun;15(3):288-98

University of Rochester, Rochester, NY, 14611, USA.

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http://dx.doi.org/10.1007/s11936-013-0238-5DOI Listing
June 2013

Rivaroxaban for thromboprophylaxis in acutely ill medical patients.

N Engl J Med 2013 Feb;368(6):513-23

Department of Vascular Surgery, King's College Hospital, London SE5 9RS, United Kingdom.

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http://www.nejm.org/doi/10.1056/NEJMoa1111096
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http://dx.doi.org/10.1056/NEJMoa1111096DOI Listing
February 2013

Novel oral anticoagulants: a review of the literature and considerations in special clinical situations.

Hosp Pract (1995) 2013 Feb;41(1):8-18

University of Rochester, School of Medicine, Rochester, NY, USA.

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http://dx.doi.org/10.3810/hp.2013.02.1008DOI Listing
February 2013

The use of weighted and scored risk assessment models for venous thromboembolism.

Thromb Haemost 2012 Dec 8;108(6):1072-6. Epub 2012 Nov 8.

James P Wilmott Cancer Center, Department of Medicine, Division of Hematology/Oncology, University of Rochester Medical Center, Rochester, NY 14642, USA.

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http://dx.doi.org/10.1160/TH12-07-0508DOI Listing
December 2012

ASHP therapeutic position statement on the role of pharmacotherapy in preventing venous thromboembolism in hospitalized patients.

Am J Health Syst Pharm 2012 Dec;69(24):2174-90

New Mexico Heart Institute, Albuquerque, NM, USA.

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http://dx.doi.org/10.2146/ajhp120236DOI Listing
December 2012

The "risk" of risk assessment models for venous thromboembolism in medical patients.

Am J Med 2012 Nov;125(11):e23-4; author reply p.e25-6

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http://dx.doi.org/10.1016/j.amjmed.2011.11.029DOI Listing
November 2012

Improving prevention and treatment of venous thromboembolism: clinical trial results.

J Med Econ 2012 28;15(4):611-22. Epub 2012 Feb 28.

Department of Outcomes Research, New Mexico Heart Institute, University of New Mexico, Albuquerque, NM 87102, USA.

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http://dx.doi.org/10.3111/13696998.2012.667026DOI Listing
October 2012

How I treat anticoagulated patients undergoing an elective procedure or surgery.

Blood 2012 Oct 28;120(15):2954-62. Epub 2012 Aug 28.

Department of Medicine, Division of Hematology/Oncology, University of Rochester Medical Center, James P. Wilmot Cancer Center, Rochester, NY, USA.

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http://dx.doi.org/10.1182/blood-2012-06-415943DOI Listing
October 2012

Periprocedural heparin bridging in patients receiving vitamin K antagonists: systematic review and meta-analysis of bleeding and thromboembolic rates.

Circulation 2012 Sep 21;126(13):1630-9. Epub 2012 Aug 21.

Department of Medicine, Division of Hematology and Thromboembolism, McMaster University, Hamilton, Ontario, Canada.

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https://www.ahajournals.org/doi/10.1161/CIRCULATIONAHA.112.1
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http://dx.doi.org/10.1161/CIRCULATIONAHA.112.105221DOI Listing
September 2012

Pro: "Bridging anticoagulation is needed during warfarin interruption in patients who require elective surgery".

Thromb Haemost 2012 Aug 12;108(2):213-6. Epub 2012 Jun 12.

Department of Medicine, Division of Hematology/Oncology, University of Rochester Medical Center, 601 Elmwood Ave, Rochester, NY 14642, USA.

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http://www.thieme-connect.de/DOI/DOI?10.1160/TH12-04-0217
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August 2012

Venous thromboembolism: annualised United States models for total, hospital-acquired and preventable costs utilising long-term attack rates.

Thromb Haemost 2012 Aug 28;108(2):291-302. Epub 2012 Jun 28.

New Mexico Heart Institute, University of New Mexico College of Pharmacy, Albuquerque, New Mexico 87102, USA.

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http://www.thieme-connect.de/DOI/DOI?10.1160/TH12-03-0162
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August 2012

Venous thromboembolism pharmacy intervention management program with an active, multifaceted approach reduces preventable venous thromboembolism and increases appropriate prophylaxis.

Clin Appl Thromb Hemost 2012 Jan-Feb;18(1):45-58. Epub 2011 Sep 23.

University of New Mexico Health Sciences Center, College of Pharmacy, University of New Mexico, Albuquerque, NM 87131-0001, USA.

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http://dx.doi.org/10.1177/1076029611405186DOI Listing
June 2012

Role of new anticoagulants for the prevention of venous thromboembolism after major orthopaedic surgery and in hospitalised acutely ill medical patients.

Thromb Haemost 2012 Jun 22;107(6):1027-34. Epub 2012 Mar 22.

University of Insubria-Ospedale di Circolo, Varese, Italy.

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http://dx.doi.org/10.1160/TH11-11-0787DOI Listing
June 2012

Deep-vein thrombosis: a United States cost model for a preventable and costly adverse event.

Thromb Haemost 2011 Sep 11;106(3):405-15. Epub 2011 Aug 11.

University of New Mexico College of Pharmacy, Albuquerque, New Mexico, USA.

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http://dx.doi.org/10.1160/TH11-02-0132DOI Listing
September 2011

Venous thromboembolism prophylaxis after hospital discharge: transition to preventive care.

Hosp Pract (1995) 2011 Aug;39(3):7-15

Department of Medicine, Henry Ford Hospital, Detroit, MI, USA.

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http://dx.doi.org/10.3810/hp.2011.08.574DOI Listing
August 2011

The eighth American college of chest physicians guidelines on venous thromboembolism prevention: implications for hospital prophylaxis strategies.

J Thromb Thrombolysis 2011 Feb;31(2):196-208

Department of Orthopedic Surgery, UT Southwestern Medical Center, 1801 Inwood Road, Dallas, TX 75390-8883, USA.

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http://link.springer.com/10.1007/s11239-010-0500-6
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February 2011

Risk assessment of venous thromboembolism in hospitalized medical patients.

Curr Opin Pulm Med 2010 Sep;16(5):419-25

McMaster University, Department of Medicine, Hamilton General Hospital, Thrombosis Unit, Hamilton, Ontario, Canada.

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http://dx.doi.org/10.1097/MCP.0b013e32833b4669DOI Listing
September 2010

Bridging therapy and oral anticoagulation: current and future prospects.

Curr Opin Hematol 2010 Sep;17(5):444-9

McMaster University, Department of Medicine, Hamilton General Hospital Thrombosis Unit, Hamilton, Ontario, Canada.

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http://dx.doi.org/10.1097/MOH.0b013e32833c077bDOI Listing
September 2010

Venous thromboembolism prophylaxis with unfractionated heparin in the hospitalized medical patient: the case for thrice daily over twice daily dosing.

Intern Emerg Med 2010 Aug 23;5(4):299-306. Epub 2010 Feb 23.

Cardinal Health Pharmacy Solutions, Lovelace Medical Center, Lovelace Rehabilitation Hospital, Lovelace Health Systems, 601 Dr. Martin Luther King Jr. Ave. NE, Albuquerque, NM, 87102, USA.

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http://link.springer.com/10.1007/s11739-010-0359-8
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August 2010

To bridge or not to bridge: that is the question. The argument FOR bridging therapy in patients on oral anticoagulants requiring temporary interruption for elective procedures.

J Thromb Thrombolysis 2010 Feb;29(2):192-8

Division of Hematology and Thromboembolism, Department of Medicine, Hamilton General Hospital, McMaster University, McMaster Clinic, 237 Barton Street East, Hamilton, ON, L8L 2X2, Canada.

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http://link.springer.com/10.1007/s11239-009-0410-7
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February 2010

Venous thromboembolism prophylaxis in the medical patient: controversies and perspectives.

Am J Med 2009 Dec;122(12):1077-84

McMaster University, Hamilton, ON, Canada.

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http://dx.doi.org/10.1016/j.amjmed.2009.04.027DOI Listing
December 2009

Rates of venous thromboembolism occurrence in medical patients among the insured population.

Thromb Haemost 2009 Nov;102(5):951-7

McMaster University, Hamilton General Hospital, Hamilton, ON L8L 2X2, Canada.

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http://dx.doi.org/10.1160/TH09-02-0073DOI Listing
November 2009

Use of emerging oral anticoagulants in clinical practice: translating results from clinical trials to orthopedic and general surgical patient populations.

Ann Surg 2009 Aug;250(2):219-28

Jefferson Center for Vascular Disease, Thomas Jefferson University Hospitals, Jefferson Medical College, Philadelphia, PA 19107, USA.

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http://dx.doi.org/10.1097/SLA.0b013e3181ae6dbeDOI Listing
August 2009