Alessio Nocentini

Alessio Nocentini

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Alessio Nocentini

Alessio Nocentini

Publications by authors named "Alessio Nocentini"

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Stereoselective pharmacokinetic and pharmacodynamic analysis of a CNS-active sulphamoylphenyl carbamate derivative.

J Enzyme Inhib Med Chem 2019 Dec;34(1):1078-1082

a Faculty of Medicine, School of Pharmacy, Institute of Drug Research , The Hebrew University of Jerusalem , Jerusalem , Israel.

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http://dx.doi.org/10.1080/14756366.2019.1612887DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6534253PMC
December 2019

Appraisal of anti-protozoan activity of nitroaromatic benzenesulfonamides inhibiting carbonic anhydrases from and .

J Enzyme Inhib Med Chem 2019 Dec;34(1):1164-1171

a Department of Neuroscience, Psychology, Drug Research and Child's Health, Section of Pharmaceutical and Nutraceutical Sciences , University of Florence , Sesto Fiorentino , Italy.

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http://dx.doi.org/10.1080/14756366.2019.1626375DOI Listing
December 2019

Activation of human α-carbonic anhydrase isoforms I, II, IV and VII with bis-histamine schiff bases and bis-spinaceamine substituted derivatives.

J Enzyme Inhib Med Chem 2019 Dec;34(1):1193-1198

b Dipartimento Neurofarba, Sezione di Scienze Farmaceutiche e Nutraceutiche , Università degli Studi di Firenze , Sesto Fiorentino , Italy.

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http://dx.doi.org/10.1080/14756366.2019.1630616DOI Listing
December 2019

Synthesis of benzensulfonamides linked to quinazoline scaffolds as novel carbonic anhydrase inhibitors.

Bioorg Chem 2019 Jun 6;87:78-90. Epub 2019 Mar 6.

Università degli Studi di Firenze, Dipartimento Neurofarba, Sezione di Scienze Farmaceutiche e Nutraceutiche, Via U. Schiff 6, 50019 Sesto Fiorentino, Florence, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.bioorg.2019.03.007DOI Listing
June 2019

Design, synthesis, and carbonic anhydrase inhibition activity of benzenesulfonamide-linked novel pyrazoline derivatives.

Bioorg Chem 2019 Jun 19;87:425-431. Epub 2019 Mar 19.

Università degli Studi di Firenze, NEUROFARBA Dept., Sezione di Scienze Farmaceutiche, Via Ugo Schiff 6, 50019 Sesto Fiorentino, Florence, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.bioorg.2019.03.052DOI Listing
June 2019

Novel synthesized SLC-0111 thiazole and thiadiazole analogues: Determination of their carbonic anhydrase inhibitory activity and molecular modeling studies.

Bioorg Chem 2019 Jun 3;87:794-802. Epub 2019 Apr 3.

Department of NEUROFARBA, Section of Pharmaceutical and Nutraceutical Sciences, University of Florence, Polo Scientifico, Via U. Schiff 6, 50019, Sesto Fiorentino, Firenze, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.bioorg.2019.04.002DOI Listing
June 2019

Benzenesulfonamides incorporating nitrogenous bases show effective inhibition of β-carbonic anhydrases from the pathogenic fungi Cryptococcus neoformans, Candida glabrata and Malassezia globosa.

Bioorg Chem 2019 May 19;86:39-43. Epub 2019 Jan 19.

University of Florence, NEUROFARBA Department, Via Ugo Schiff 6, 50019 Sesto Fiorentino, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.bioorg.2019.01.030DOI Listing
May 2019

Click-tailed benzenesulfonamides as potent bacterial carbonic anhydrase inhibitors for targeting Mycobacterium tuberculosis and Vibrio cholerae.

Bioorg Chem 2019 May 29;86:183-186. Epub 2019 Jan 29.

University of Florence, Department of Neuroscience, Psychology, Drug Research and Child's Health, Section of Pharmaceutical and Nutraceutical Sciences, via Ugo Schiff 6, 50019 Sesto Fiorentino, Italy; Department of Chemistry, College of Science, King Saud University, Riyadh, Saudi Arabia. Electronic address:

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http://dx.doi.org/10.1016/j.bioorg.2019.01.065DOI Listing
May 2019

Polypharmacology of epacadostat: a potent and selective inhibitor of the tumor associated carbonic anhydrases IX and XII.

Chem Commun (Camb) 2019 May;55(40):5720-5723

University of Florence, NEUROFARBA Dept., Sezione di Farmaceutica e Nutraceutica, Via Ugo Schiff 6, Sesto Fiorentino, 50019, Florence, Italy.

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http://xlink.rsc.org/?DOI=C8CC09568J
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http://dx.doi.org/10.1039/c8cc09568jDOI Listing
May 2019

-Nitrosulfonamides as Carbonic Anhydrase Inhibitors: A Promising Chemotype for Targeting Chagas Disease and Leishmaniasis.

ACS Med Chem Lett 2019 Apr 27;10(4):413-418. Epub 2018 Nov 27.

Department of NEUROFARBA, Pharmaceutical and Nutraceutical Section, University of Florence, Via U. Schiff 6, 50019 Sesto Fiorentino (Firenze), Italy.

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http://dx.doi.org/10.1021/acsmedchemlett.8b00430DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6466549PMC
April 2019

α,γ-Diketocarboxylic Acids and Their Esters Act as Carbonic Anhydrase IX and XII Selective Inhibitors.

ACS Med Chem Lett 2019 Apr 19;10(4):661-665. Epub 2019 Feb 19.

Department of NEUROFARBA, Section of Pharmaceutical and Nutraceutical Sciences, University of Florence, Polo Scientifico, Via U. Schiff 6, 50019 Sesto Fiorentino, Firenze, Italy.

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http://dx.doi.org/10.1021/acsmedchemlett.9b00023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6466837PMC
April 2019

4-Substituted benzenesulfonamides featuring cyclic imides moieties exhibit potent and isoform-selective carbonic anhydrase II/IX inhibition.

Bioorg Chem 2019 Mar 19;83:198-204. Epub 2018 Oct 19.

NEUROFARBA Department - Pharmaceutical and Nutraceutical Section, Laboratory of Molecular Modeling Cheminformatics & QSAR University of Florence, Via Ugo Schiff 6, 50019 Sesto Fiorentino, Florence, Italy; NEUROFARBA Department - Pharmaceutical and Nutraceutical Section, University of Florence, Via Ugo Schiff 6, 50019 Sesto Fiorentino, Florence, Italy. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00452068183094
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http://dx.doi.org/10.1016/j.bioorg.2018.10.037DOI Listing
March 2019

α-Carbonic anhydrases are strongly activated by spinaceamine derivatives.

Bioorg Med Chem 2019 Mar 21;27(5):800-804. Epub 2019 Jan 21.

Università degli Studi di Firenze, Dipartimento Neurofarba, Sezione di Scienze Farmaceutiche e Nutraceutiche, Via U. Schiff 6, 50019 Sesto Fiorentino, Florence, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.bmc.2019.01.017DOI Listing
March 2019

Phosphorus versus Sulfur: Discovery of Benzenephosphonamidates as Versatile Sulfonamide-Mimic Chemotypes Acting as Carbonic Anhydrase Inhibitors.

Chemistry 2019 Jan 14;25(5):1188-1192. Epub 2018 Dec 14.

Department NEUROFARBA-Pharmaceutical and nutraceutical section, University of Firenze, via Ugo Schiff 6, 50019, Sesto Fiorentino, Italy.

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http://doi.wiley.com/10.1002/chem.201805039
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http://dx.doi.org/10.1002/chem.201805039DOI Listing
January 2019

Selenols: a new class of carbonic anhydrase inhibitors.

Chem Commun (Camb) 2019 Jan;55(5):648-651

University of Florence, NEUROFARBA Department, Sezione di Scienze Farmaceutiche, Via Ugo Schiff 6, 50019 Sesto Fiorentino, Florence, Italy.

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http://dx.doi.org/10.1039/c8cc08562eDOI Listing
January 2019

Carbonic anhydrases from Trypanosoma cruzi and Leishmania donovani chagasi are inhibited by benzoxaboroles.

J Enzyme Inhib Med Chem 2018 Dec;33(1):286-289

a Institut des Biomolécules Max Mousseron (IBMM), UMR 5247 CNRS, ENSCM, Université de Montpellier , Montpellier Cedex , France.

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http://dx.doi.org/10.1080/14756366.2017.1414808DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6009872PMC
December 2018

Tumor-associated carbonic anhydrase isoform IX and XII inhibitory properties of certain isatin-bearing sulfonamides endowed with in vitro antitumor activity towards colon cancer.

Bioorg Chem 2018 12 7;81:425-432. Epub 2018 Sep 7.

Department of NEUROFARBA, Section of Pharmaceutical and Nutraceutical Sciences, University of Florence, Polo Scientifico, Via U. Schiff 6, 50019 Sesto Fiorentino, Firenze, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.bioorg.2018.09.007DOI Listing
December 2018

Steroids interfere with human carbonic anhydrase activity by using alternative binding mechanisms.

J Enzyme Inhib Med Chem 2018 Dec;33(1):1453-1459

b Department of NEUROFARBA, Pharmaceutical and Nutraceutical Section , University of Florence , Firenze , Italy.

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http://dx.doi.org/10.1080/14756366.2018.1512597DOI Listing
December 2018

Carbonic anhydrase inhibition with a series of novel benzenesulfonamide-triazole conjugates.

J Enzyme Inhib Med Chem 2018 Dec;33(1):1565-1574

b NEUROFARBA Department, Pharmaceutical and Nutraceutical Sciences Section , University of Florence , Firenze , Italy.

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https://www.tandfonline.com/doi/full/10.1080/14756366.2018.1
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http://dx.doi.org/10.1080/14756366.2018.1513927DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6171417PMC
December 2018

4-Hydroxy-3-nitro-5-ureido-benzenesulfonamides Selectively Target the Tumor-Associated Carbonic Anhydrase Isoforms IX and XII Showing Hypoxia-Enhanced Antiproliferative Profiles.

J Med Chem 2018 Dec 28;61(23):10860-10874. Epub 2018 Nov 28.

NEUROFARBA Dept., Sezione di Scienze Farmaceutiche , Università degli Studi di Firenze , Via Ugo Schiff 6 , 50019 Sesto Fiorentino Florence , Italy.

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http://dx.doi.org/10.1021/acs.jmedchem.8b01504DOI Listing
December 2018

Synthesis of novel isoindoline-1,3-dione-based oximes and benzenesulfonamide hydrazones as selective inhibitors of the tumor-associated carbonic anhydrase IX.

Bioorg Chem 2018 10 24;80:706-713. Epub 2018 Jul 24.

NEUROFARBA Department, University of Florence, Via Ugo Schiff 6, 50019 Sesto Fiorentino (Florence), Italy. Electronic address:

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http://dx.doi.org/10.1016/j.bioorg.2018.07.027DOI Listing
October 2018

Carbonic anhydrase inhibitors as antitumor/antimetastatic agents: a patent review (2008-2018).

Expert Opin Ther Pat 2018 10 9;28(10):729-740. Epub 2018 Aug 9.

a Department of NEUROFARBA, Section of Pharmaceutical and Nutraceutical Sciences , University of Florence , Sesto Fiorentino (Firenze) , Italy.

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http://dx.doi.org/10.1080/13543776.2018.1508453DOI Listing
October 2018

Novel hydrazido benzenesulfonamides-isatin conjugates: Synthesis, carbonic anhydrase inhibitory activity and molecular modeling studies.

Eur J Med Chem 2018 Sep 24;157:28-36. Epub 2018 Jul 24.

Department of NEUROFARBA, Section of Pharmaceutical and Nutraceutical Sciences, University of Florence, Polo Scientifico, Via U. Schiff 6, 50019, Sesto Fiorentino, Firenze, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.ejmech.2018.07.054DOI Listing
September 2018

Evaluation of Tc-sulfonamide and sulfocoumarin derivatives for imaging carbonic anhydrase IX expression.

J Inorg Biochem 2018 08 13;185:63-70. Epub 2018 Apr 13.

Department of Chemistry, Simon Fraser University, Burnaby, BC V5A 1S6, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.jinorgbio.2018.04.009DOI Listing
August 2018

Deciphering the Mechanism of Human Carbonic Anhydrases Inhibition with Sulfocoumarins: Computational and Experimental Studies.

Chemistry 2018 Jun 3;24(31):7840-7844. Epub 2018 May 3.

Department NEUROFARBA-Pharmaceutical and nutraceutical section, Laboratory of Molecular Modeling Cheminformatics & QSAR, University of Firenze, via Ugo Schiff 6, 50019, Sesto Fiorentino, Italy.

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http://dx.doi.org/10.1002/chem.201800941DOI Listing
June 2018

Benzoxaborole compounds for therapeutic uses: a patent review (2010- 2018).

Expert Opin Ther Pat 2018 06 11;28(6):493-504. Epub 2018 May 11.

b Institut des Biomolécules Max Mousseron (IBMM), UMR 5247 CNRS, ENSCM , Université de Montpellier , Montpellier , France.

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http://dx.doi.org/10.1080/13543776.2018.1473379DOI Listing
June 2018

Discovery of β-Adrenergic Receptors Blocker-Carbonic Anhydrase Inhibitor Hybrids for Multitargeted Antiglaucoma Therapy.

J Med Chem 2018 06 13;61(12):5380-5394. Epub 2018 Jun 13.

Department of NEUROFARBA, Section of Pharmaceutical and Nutraceutical Sciences , University of Florence, Polo Scientifico , Via U. Schiff 6 , 50019 Sesto Fiorentino , Firenze Italy.

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http://dx.doi.org/10.1021/acs.jmedchem.8b00625DOI Listing
June 2018

Dual-tail arylsulfone-based benzenesulfonamides differently match the hydrophobic and hydrophilic halves of human carbonic anhydrases active sites: Selective inhibitors for the tumor-associated hCA IX isoform.

Eur J Med Chem 2018 May 10;152:1-9. Epub 2018 Apr 10.

Università degli Studi di Firenze, Department NEUROFARBA - Pharmaceutical and Nutraceutical section, University of Firenze, via Ugo Schiff 6, I-50019, Sesto Fiorentino, Firenze, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.ejmech.2018.04.016DOI Listing
May 2018

Discovery of thiazolin-4-one-based aromatic sulfamates as a new class of carbonic anhydrase isoforms I, II, IV, and IX inhibitors.

Bioorg Chem 2018 04 31;77:293-299. Epub 2018 Jan 31.

Department NEUROFARBA - Pharmaceutical and Nutraceutical Section, University of Firenze, via Ugo Schiff 6, I-50019 Sesto Fiorentino, Firenze, Italy.

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http://dx.doi.org/10.1016/j.bioorg.2018.01.023DOI Listing
April 2018

Synthesis, biological evaluation and computational studies of novel iminothiazolidinone benzenesulfonamides as potent carbonic anhydrase II and IX inhibitors.

Bioorg Chem 2018 04 31;77:381-386. Epub 2018 Jan 31.

Università degli Studi di Firenze, Department NEUROFARBA - Pharmaceutical and Nutraceutical Section, University of Firenze, via Ugo Schiff 6, I-50019 Sesto Fiorentino, Firenze, Italy.

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http://dx.doi.org/10.1016/j.bioorg.2018.01.031DOI Listing
April 2018

Synthesis and biological evaluation of novel pyrazoline-based aromatic sulfamates with potent carbonic anhydrase isoforms II, IV and IX inhibitory efficacy.

Bioorg Chem 2018 04 23;77:633-639. Epub 2018 Feb 23.

Department NEUROFARBA - Pharmaceutical and Nutraceutical Section, University of Firenze, via Ugo Schiff 6, I-50019 Sesto Fiorentino, Firenze, Italy.

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http://dx.doi.org/10.1016/j.bioorg.2018.02.021DOI Listing
April 2018

Natural Polyphenols Selectively Inhibit β-Carbonic Anhydrase from the Dandruff-Producing Fungus Malassezia globosa: Activity and Modeling Studies.

ChemMedChem 2018 04 25;13(8):816-823. Epub 2018 Mar 25.

Department NEUROFARBA-Pharmaceutical and Nutraceutical Section, University of Florence, via Ugo Schiff 6, 50019, Sesto Fiorentino, Italy.

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http://dx.doi.org/10.1002/cmdc.201800015DOI Listing
April 2018

Discovery of New Sulfonamide Carbonic Anhydrase IX Inhibitors Incorporating Nitrogenous Bases.

ACS Med Chem Lett 2017 Dec 21;8(12):1314-1319. Epub 2017 Nov 21.

Department of NEUROFARBA, Pharmaceutical and Nutraceutical section, University of Florence, Via Ugo Schiff 6, Sesto Fiorentino, 50019 Florence, Italy.

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http://pubs.acs.org/doi/10.1021/acsmedchemlett.7b00399
Publisher Site
http://dx.doi.org/10.1021/acsmedchemlett.7b00399DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5733260PMC
December 2017

Benzoxaboroles as Efficient Inhibitors of the β-Carbonic Anhydrases from Pathogenic Fungi: Activity and Modeling Study.

ACS Med Chem Lett 2017 Nov 20;8(11):1194-1198. Epub 2017 Oct 20.

Institut des Biomolécules Max Mousseron (IBMM), UMR 5247 CNRS, ENSCM, Université de Montpellier, 240 avenue du Professeur Emile Jeanbrau, 34296 Montpellier Cedex 05, France.

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http://dx.doi.org/10.1021/acsmedchemlett.7b00369DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5682618PMC
November 2017

Synthesis and carbonic anhydrase inhibition of polycyclic imides incorporating N-benzenesulfonamide moieties.

Bioorg Med Chem 2017 10 29;25(20):5373-5379. Epub 2017 Jul 29.

Università degli Studi di Firenze, NEUROFARBA Dept., Sezione di Scienze Farmaceutiche, Via Ugo Schiff 6, 50019 Sesto Fiorentino, Florence, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.bmc.2017.07.056DOI Listing
October 2017

Novel 4/3-((4-oxo-5-(2-oxoindolin-3-ylidene)thiazolidin-2-ylidene)amino) benzenesulfonamides: Synthesis, carbonic anhydrase inhibitory activity, anticancer activity and molecular modelling studies.

Eur J Med Chem 2017 Oct 1;139:250-262. Epub 2017 Aug 1.

Department of NEUROFARBA, Section of Pharmaceutical and Nutraceutical Sciences, University of Florence, Polo Scientifico, Via U. Schiff 6, 50019, Sesto Fiorentino, Firenze, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.ejmech.2017.07.073DOI Listing
October 2017

Design and Comparative Evaluation of the Anticonvulsant Profile, Carbonic-Anhydrate Inhibition and Teratogenicity of Novel Carbamate Derivatives of Branched Aliphatic Carboxylic Acids with 4-Aminobenzensulfonamide.

Neurochem Res 2017 Jul 9;42(7):1972-1982. Epub 2017 Mar 9.

Faculty of Medicine, School of Pharmacy, Institute of Drug Research, The Hebrew University of Jerusalem, Jerusalem, Israel.

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http://dx.doi.org/10.1007/s11064-017-2216-xDOI Listing
July 2017

Synthesis and biological evaluation of novel aromatic and heterocyclic bis-sulfonamide Schiff bases as carbonic anhydrase I, II, VII and IX inhibitors.

Bioorg Med Chem 2017 06 31;25(12):3093-3097. Epub 2017 Mar 31.

Università degli Studi di Firenze, NEUROFARBA Dept., Sezione di Scienze Farmaceutiche, Via Ugo Schiff 6, 50019 Sesto Fiorentino (Florence), Italy. Electronic address:

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http://dx.doi.org/10.1016/j.bmc.2017.03.063DOI Listing
June 2017

Inhibition of Malassezia globosa carbonic anhydrase with phenols.

Bioorg Med Chem 2017 05 18;25(9):2577-2582. Epub 2017 Mar 18.

Università degli Studi di Firenze, Department NEUROFARBA - Pharmaceutical and Nutraceutical Section, University of Firenze, via Ugo Schiff 6, I-50019 Sesto Fiorentino, Firenze, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.bmc.2017.03.026DOI Listing
May 2017

Synthesis of bulky-tailed sulfonamides incorporating pyrido[2,3-d][1,2,4]triazolo[4,3-a]pyrimidin-1(5H)-yl) moieties and evaluation of their carbonic anhydrases I, II, IV and IX inhibitory effects.

Bioorg Med Chem 2017 04 21;25(7):2210-2217. Epub 2017 Feb 21.

Department of NEUROFARBA, Section of Pharmaceutical and Nutraceutical Sciences, University of Florence, Polo Scientifico, Via U. Schiff 6, 50019 Sesto, Fiorentino, Firenze, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.bmc.2017.02.037DOI Listing
April 2017

Dithiocarbamates effectively inhibit the β-carbonic anhydrase from the dandruff-producing fungus Malassezia globosa.

Bioorg Med Chem 2017 02 27;25(3):1260-1265. Epub 2016 Dec 27.

Università degli Studi di Firenze, Dipartimento Neurofarba, Sezione di Scienze Farmaceutiche, Polo Scientifico, Sesto Fiorentino, Firenze, Italy; Department of Chemistry, College of Science, King Saud University, P.O. Box 2455, Riyadh 11451, Saudi Arabia. Electronic address:

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http://dx.doi.org/10.1016/j.bmc.2016.12.040DOI Listing
February 2017

Novel indolin-2-one-based sulfonamides as carbonic anhydrase inhibitors: Synthesis, in vitro biological evaluation against carbonic anhydrases isoforms I, II, IV and VII and molecular docking studies.

Eur J Med Chem 2017 Feb 11;127:521-530. Epub 2017 Jan 11.

Department of NEUROFARBA, Section of Pharmaceutical and Nutraceutical Sciences, University of Florence, Polo Scientifico, Via U. Schiff 6, 50019, Sesto Fiorentino (Firenze), Italy. Electronic address:

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http://dx.doi.org/10.1016/j.ejmech.2017.01.017DOI Listing
February 2017

Synthesis of isoxazole-containing sulfonamides with potent carbonic anhydrase II and VII inhibitory properties.

Bioorg Med Chem 2017 02 11;25(4):1456-1464. Epub 2017 Jan 11.

Università degli Studi di Firenze, NEUROFARBA Dept., Sezione di Scienze Farmaceutiche, Via Ugo Schiff 6, 50019 Sesto Fiorentino, Florence, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.bmc.2017.01.008DOI Listing
February 2017

7-Aryl-triazolyl-substituted sulfocoumarins are potent, selective inhibitors of the tumor-associated carbonic anhydrase IX and XII.

J Enzyme Inhib Med Chem 2016 Dec 18;31(6):1226-33. Epub 2015 Dec 18.

a University of Florence, Neurofarba Department, Sesto Fiorentino , Firenze , Italy and.

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http://dx.doi.org/10.3109/14756366.2015.1115401DOI Listing
December 2016

Benzenesulfonamides Incorporating Flexible Triazole Moieties Are Highly Effective Carbonic Anhydrase Inhibitors: Synthesis and Kinetic, Crystallographic, Computational, and Intraocular Pressure Lowering Investigations.

J Med Chem 2016 12 21;59(23):10692-10704. Epub 2016 Nov 21.

Università degli Studi di Firenze , Neurofarba Department., Sezione di Scienze Farmaceutiche, Via Ugo Schiff 6, 50019 Sesto Fiorentino (Florence), Italy.

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http://dx.doi.org/10.1021/acs.jmedchem.6b01389DOI Listing
December 2016

N-Nitrosulfonamides: A new chemotype for carbonic anhydrase inhibition.

Bioorg Med Chem 2016 08 30;24(16):3612-7. Epub 2016 May 30.

Università degli Studi di Firenze, NEUROFARBA Dept., Sezione di Scienze Farmaceutiche, Via Ugo Schiff 6, 50019 Sesto Fiorentino (Florence), Italy. Electronic address:

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http://dx.doi.org/10.1016/j.bmc.2016.05.072DOI Listing
August 2016

Solution and Solid-State Analysis of Binding of 13-Substituted Berberine Analogues to Human Telomeric G-quadruplexes.

Chem Asian J 2016 Apr 11;11(7):1107-15. Epub 2016 Mar 11.

Department NEUROFARBA-Pharmaceutical and nutraceutical section, Laboratory of Molecular Modeling Cheminformatics&QSAR, University of Firenze, via Ugo Schiff 6, 50019, Sesto Fiorentino, Firenze, Italy.

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http://dx.doi.org/10.1002/asia.201600116DOI Listing
April 2016

Click-tailed coumarins with potent and selective inhibitory action against the tumor-associated carbonic anhydrases IX and XII.

Bioorg Med Chem 2015 Nov 28;23(21):6955-66. Epub 2015 Sep 28.

Università degli Studi di Firenze, Dipartimento Neurofarba, Sezione di Scienze Farmaceutiche, Polo Scientifico, Via U. Schiff 6, 50019 Sesto Fiorentino, Florence, Italy; Università degli Studi di Firenze, Dipartimento di Chimica, Laboratorio di Chimica Bioinorganica, Rm. 188, Via della Lastruccia 3, 50019 Sesto Fiorentino, Florence, Italy. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S09680896153006
Publisher Site
http://dx.doi.org/10.1016/j.bmc.2015.09.041DOI Listing
November 2015