Publications by authors named "Alessio Lanna"

16Publications

Measuring Telomerase Activity in Senescent Human T Cells Upon Genetic Modification.

Authors:
Alessio Lanna

Methods Mol Biol 2017 ;1514:119-126

Division of Infection and Immunity, University College London, The Rayne Building, London, UK.

View Article and Find Full Text PDF
January 2018

Senescence of T Lymphocytes: Implications for Enhancing Human Immunity.

Trends Immunol 2016 12 4;37(12):866-876. Epub 2016 Oct 4.

Division of Infection and Immunity, University College London, London, UK; Nuffield Department of Medicine, University of Oxford, Oxford, UK.

View Article and Find Full Text PDF
December 2016

Mitochondrial fusion fuels T cell memory.

Cell Res 2016 09 12;26(9):969-70. Epub 2016 Aug 12.

Kennedy Institute of Rheumatology, NDORMS, University of Oxford, Oxford 0X3 7FY, UK.

View Article and Find Full Text PDF
September 2016

The kinase p38 activated by the metabolic regulator AMPK and scaffold TAB1 drives the senescence of human T cells.

Nat Immunol 2014 Oct 24;15(10):965-72. Epub 2014 Aug 24.

Division of Infection and Immunity, University College London, London, UK.

View Article and Find Full Text PDF
October 2014

Anti-melanoma vaccines engineered to simultaneously modulate cytokine priming and silence PD-L1 characterized using myeloid-derived suppressor cells as a readout of therapeutic efficacy.

Oncoimmunology 2014;3(7):e945378. Epub 2014 Jul 3.

Division of infection and immunity; Rayne Institute; University College London ; London, UK ; Immunomodulation group; Navarrabiomed-Fundacion Miguel Servet ; Pamplona, Navarra, Spain.

View Article and Find Full Text PDF
July 2014

Assessing T-cell responses in anticancer immunotherapy: Dendritic cells or myeloid-derived suppressor cells?

Oncoimmunology 2013 Oct 12;2(10):e26148. Epub 2013 Sep 12.

Rayne Institute; University College London; London, UK ; Navarrabiomed-Fundacion Miguel Servet; Complejo Hospitalario de Navarra; Pamplona, Spain.

View Article and Find Full Text PDF
October 2013

IFN-α inhibits telomerase in human CD8⁺ T cells by both hTERT downregulation and induction of p38 MAPK signaling.

J Immunol 2013 Oct 30;191(7):3744-52. Epub 2013 Aug 30.

Pharmacology Section, Department of System Medicine, University of Rome Tor Vergata, 00133, Rome, Italy;

View Article and Find Full Text PDF
October 2013

Retroviral and lentiviral vectors for the induction of immunological tolerance.

Scientifica (Cairo) 2012 Dec;2012

Division of Infection and Immunity. Rayne Institute. University College London. 5 University Street. WC1E 6JF. London. United Kingdom. ; Department of Physiology-Immunology. Medical School. Free University of Brussels. Laarbeeklaan 103. 1090 Jette. Belgium.

View Article and Find Full Text PDF
December 2012

PD-L1/PD-1 Co-Stimulation, a Brake for T cell Activation and a T cell Differentiation Signal.

J Clin Cell Immunol 2012 Oct;S12

Division of Infection and Immunity, Rayne Institute, University College London, 5 University Street, WC1E 6JF, London, UK.

View Article and Find Full Text PDF
October 2012

Molecular mechanisms involved in HIV-1-Tat mediated inhibition of telomerase activity in human CD4(+) T lymphocytes.

Mol Immunol 2013 Jun 31;54(2):181-92. Epub 2012 Dec 31.

Department of System Medicine, Pharmacology Section, University of Rome Tor Vergata, Rome, Italy.

View Article and Find Full Text PDF
June 2013

MODULATING CO-STIMULATION DURING ANTIGEN PRESENTATION TO ENHANCE CANCER IMMUNOTHERAPY.

Immunol Endocr Metab Agents Med Chem 2012 Sep;12(3):224-235

Division of Infection and Immunity. Rayne Institute. University College London. 5 University Street. WC1E 6JF. London. United Kingdom.

View Article and Find Full Text PDF
September 2012