Alessia Perino

Alessia Perino

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Alessia Perino

Alessia Perino

Publications by authors named "Alessia Perino"

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TGR5 signalling promotes mitochondrial fission and beige remodelling of white adipose tissue.

Nat Commun 2018 01 16;9(1):245. Epub 2018 Jan 16.

Institute of Bioengineering, Ecole Polytechnique Fédérale de Lausanne, CH-1015, Lausanne, Switzerland.

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http://dx.doi.org/10.1038/s41467-017-02068-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5770450PMC
January 2018

Bile acids deoxycholic acid and ursodeoxycholic acid differentially regulate human β-defensin-1 and -2 secretion by colonic epithelial cells.

FASEB J 2017 09 9;31(9):3848-3857. Epub 2017 May 9.

Department of Molecular Medicine, Royal College of Surgeons in Ireland, Education and Research Centre, Beaumont Hospital, Dublin, Ireland;

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http://dx.doi.org/10.1096/fj.201601365RDOI Listing
September 2017

Inhibiting poly ADP-ribosylation increases fatty acid oxidation and protects against fatty liver disease.

J Hepatol 2017 01 20;66(1):132-141. Epub 2016 Sep 20.

Laboratory of Integrative and Systems Physiology, École Polytechnique Fédérale de Lausanne, CH-1015 Lausanne, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.jhep.2016.08.024DOI Listing
January 2017

Rac signal adaptation controls neutrophil mobilization from the bone marrow.

Sci Signal 2016 12 20;9(459):ra124. Epub 2016 Dec 20.

Department of Molecular Biotechnology and Health Sciences, Molecular Biotechnology Center, University of Torino, Via Nizza 52, 10126 Torino, Italy.

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http://dx.doi.org/10.1126/scisignal.aah5882DOI Listing
December 2016

TGR5 and Immunometabolism: Insights from Physiology and Pharmacology.

Trends Pharmacol Sci 2015 Dec 2;36(12):847-857. Epub 2015 Nov 2.

Metabolic Signaling, Institute of Bioengineering, School of Life Sciences, Ecole Polytechnique Fédérale de Lausanne, CH-1015 Lausanne, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.tips.2015.08.002DOI Listing
December 2015

A SIRT7-dependent acetylation switch of GABPβ1 controls mitochondrial function.

Cell Metab 2014 Nov 4;20(5):856-869. Epub 2014 Sep 4.

Laboratory of Integrative and Systems Physiology, School of Life Sciences, École Polytechnique Fédérale de Lausanne, 1015 Lausanne, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.cmet.2014.08.001DOI Listing
November 2014

SUMOylation-dependent LRH-1/PROX1 interaction promotes atherosclerosis by decreasing hepatic reverse cholesterol transport.

Cell Metab 2014 Oct 28;20(4):603-13. Epub 2014 Aug 28.

Metabolic Signaling, Institute of Bioengineering, School of Life Sciences, Ecole Polytechnique Fédérale de Lausanne, 1015 Lausanne, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.cmet.2014.07.023DOI Listing
October 2014

Phosphoinositide 3-kinases in health and disease.

Subcell Biochem 2012 ;58:183-213

Molecular Biotechnology Center, Department of Genetics, Biology and Biochemistry, University of Torino, Torino, Italy.

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http://dx.doi.org/10.1007/978-94-007-3012-0_6DOI Listing
August 2014

Another Shp on the horizon for bile acids.

Cell Metab 2014 Aug;20(2):203-5

Metabolic Signaling, Institute of Bioengineering, School of Life Sciences, Ecole Polytechnique Fédérale de Lausanne, 1015 Lausanne, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.cmet.2014.07.019DOI Listing
August 2014

Vitamin D and energy homeostasis: of mice and men.

Nat Rev Endocrinol 2014 Feb 19;10(2):79-87. Epub 2013 Nov 19.

Clinical and Experimental Endocrinology, KU Leuven, O&NI Herestraat 49 - bus 902, 3000 Leuven, Belgium.

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http://dx.doi.org/10.1038/nrendo.2013.226DOI Listing
February 2014

Phosphoinositides and cardiovascular diseases.

Curr Top Microbiol Immunol 2012 ;362:43-60

Department of Genetics, Biology and Biochemistry, University of Torino, Molecular Biotechnology Center, Italy.

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http://dx.doi.org/10.1007/978-94-007-5025-8_2DOI Listing
April 2013

NADPH oxidases in heart failure: poachers or gamekeepers?

Antioxid Redox Signal 2013 Mar 27;18(9):1024-41. Epub 2012 Aug 27.

Cardiovascular Division, James Black Centre, King's College London British Heart Foundation Centre of Excellence, London, UK.

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http://dx.doi.org/10.1089/ars.2012.4550DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3567780PMC
March 2013

Therapeutic applications of PI3K inhibitors in cardiovascular diseases.

Future Med Chem 2013 Mar;5(4):479-92

University of Torino, Molecular Biotechnology Center, Department of Molecular Biotechnology & Health Sciences, Via Nizza 52, 10126, Torino, Italy.

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http://dx.doi.org/10.4155/fmc.13.11DOI Listing
March 2013

Blockade of phosphatidylinositol 3-kinase PI3Kδ or PI3Kγ reduces IL-17 and ameliorates imiquimod-induced psoriasis-like dermatitis.

J Immunol 2012 Nov 28;189(9):4612-20. Epub 2012 Sep 28.

Rheumatology Research, Merck Serono S.A., 1211 Geneva, Switzerland.

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http://dx.doi.org/10.4049/jimmunol.1103173DOI Listing
November 2012

Anchoring proteins as regulators of signaling pathways.

Circ Res 2012 Aug;111(4):482-92

Molecular Biotechnology Center, Department of Genetics, Biology and Biochemistry, University of Torino, Torino, Italy.

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http://dx.doi.org/10.1161/CIRCRESAHA.111.262899DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3508715PMC
August 2012

Measuring PI3K lipid kinase activity.

Methods Mol Biol 2012 ;795:55-67

Department of Genetics, Biology and Biochemistry, Molecular Biotechnology Center, University of Torino, Torino, Italy.

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http://dx.doi.org/10.1007/978-1-61779-337-0_4DOI Listing
January 2012

Specific PI3K isoform modulation in heart failure: lessons from transgenic mice.

Curr Heart Fail Rep 2011 Sep;8(3):168-75

Molecular Biotechnology Center, University of Torino, Via Nizza 52, 10126, Torino, Italy.

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http://dx.doi.org/10.1007/s11897-011-0059-3DOI Listing
September 2011

Leukocyte and cardiac phosphoinositide 3-kinase γ activity in pressure overload-induced cardiac failure.

Trends Cardiovasc Med 2010 Nov;20(8):273-6

Department of Genetics, Biology and Biochemistry, Molecular Biotechnology Center, University of Torino, 10126 Torino, Italy.

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http://dx.doi.org/10.1016/j.tcm.2011.12.007DOI Listing
November 2010

PI3K kinase and scaffold functions in heart.

Ann N Y Acad Sci 2010 Feb;1188:39-45

Molecular Biotechnology Center, University of Torino, 10126 Torino, Italy.

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http://dx.doi.org/10.1111/j.1749-6632.2009.05081.xDOI Listing
February 2010

Phosphoinositide 3-kinase signalling in the vascular system.

Cardiovasc Res 2009 May 26;82(2):261-71. Epub 2008 Nov 26.

Molecular Biotechnology Center, University of Torino, via Nizza 52, 10126 Torino, Italy.

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http://dx.doi.org/10.1093/cvr/cvn325DOI Listing
May 2009

Twice upon a time: PI3K's secret double life exposed.

Trends Biochem Sci 2009 May 17;34(5):244-8. Epub 2009 Apr 17.

Molecular Biotechnology Center, Torino, Italy.

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http://dx.doi.org/10.1016/j.tibs.2009.02.003DOI Listing
May 2009