Publications by authors named "Alessia Grozio"

28Publications

NAD metabolism and its roles in cellular processes during ageing.

Nat Rev Mol Cell Biol 2020 Dec 22. Epub 2020 Dec 22.

Buck Institute for Research on Aging, Novato, CA, USA.

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December 2020

Reply to: Absence of evidence that Slc12a8 encodes a nicotinamide mononucleotide transporter.

Nat Metab 2019 07 12;1(7):662-665. Epub 2019 Jul 12.

Department of Developmental Biology, Washington University School of Medicine, St. Louis, MO, USA.

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July 2019

Differential modulation of SIRT6 deacetylase and deacylase activities by lysine-based small molecules.

Mol Divers 2020 Aug 25;24(3):655-671. Epub 2019 Jun 25.

Department of Experimental Medicine, Section of Biochemistry, and CEBR, University of Genoa, V.le Benedetto XV 1, 16132, Genoa, Italy.

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August 2020

Slc12a8 is a nicotinamide mononucleotide transporter.

Nat Metab 2019 01 7;1(1):47-57. Epub 2019 Jan 7.

Department of Developmental Biology, Washington University School of Medicine,, St. Louis, MO 63110, USA.

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January 2019

SIRT6 deacetylase activity regulates NAMPT activity and NAD(P)(H) pools in cancer cells.

FASEB J 2019 03 4;33(3):3704-3717. Epub 2018 Dec 4.

Section of Biochemistry, Department of Experimental Medicine, Center for Excellence in Biomedical Research (CEBR), University of Genoa, Genoa, Italy.

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March 2019

SIRT6 inhibitors with salicylate-like structure show immunosuppressive and chemosensitizing effects.

Bioorg Med Chem 2017 10 19;25(20):5849-5858. Epub 2017 Sep 19.

Department of Experimental Medicine, Section of Biochemistry, University of Genoa, V.le Benedetto XV 1, 16132 Genoa, Italy; CEBR, University of Genova, V.le Benedetto XV, 7, 16132 Genoa, Italy. Electronic address:

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October 2017

Long-Term Administration of Nicotinamide Mononucleotide Mitigates Age-Associated Physiological Decline in Mice.

Cell Metab 2016 12 27;24(6):795-806. Epub 2016 Oct 27.

Department of Developmental Biology, Washington University School of Medicine, St. Louis, MO 63110, USA. Electronic address:

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December 2016

Quinazolinedione SIRT6 inhibitors sensitize cancer cells to chemotherapeutics.

Eur J Med Chem 2015 Sep 14;102:530-9. Epub 2015 Aug 14.

Department of Experimental, Diagnostic and Specialty Medicine (DIMES), Alma Mater Studiorum, University of Bologna, Via S. Giacomo 14, 40126 Bologna, Italy; Institute of Organic Synthesis and Photoreactivity (ISOF), National Research Council (CNR), Via P. Gobetti 101, 40129 Bologna, Italy. Electronic address:

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September 2015

Synthesis, structural characterization and effect on human granulocyte intracellular cAMP levels of abscisic acid analogs.

Bioorg Med Chem 2015 Jan 27;23(1):22-32. Epub 2014 Nov 27.

Department of Experimental Medicine, Section of Biochemistry, University of Genoa, Viale Benedetto XV 1, 16132 Genoa, Italy; Center of Excellence for Biomedical Research (CEBR), University of Genoa, Viale Benedetto XV 5, 16132 Genoa, Italy. Electronic address:

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January 2015

Discovery of novel and selective SIRT6 inhibitors.

J Med Chem 2014 Jun 19;57(11):4796-804. Epub 2014 May 19.

Department of Experimental, Diagnostic and Specialty Medicine (DIMES), Alma Mater Studiorum, University of Bologna , Via S. Giacomo 14, 40126 Bologna, Italy.

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June 2014

CD73 protein as a source of extracellular precursors for sustained NAD+ biosynthesis in FK866-treated tumor cells.

J Biol Chem 2013 Sep 23;288(36):25938-49. Epub 2013 Jul 23.

Department of Experimental Medicine, Section of Biochemistry, and Center of Excellence for Biomedical Research, University of Genova, Viale Benedetto XV 1, 16132 Genova, Italy.

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September 2013

Rejuvenating sirtuins: the rise of a new family of cancer drug targets.

Curr Pharm Des 2013 ;19(4):614-23

Room 221, Department of Internal Medicine, University of Genoa, V.le Benedetto XV 6, 16132 Genoa, Italy.

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July 2013

Binding of abscisic acid to human LANCL2.

Biochem Biophys Res Commun 2011 Nov 20;415(2):390-5. Epub 2011 Oct 20.

Department of Experimental Medicine (DIMES), Section of Biochemistry, and Center of Excellence for Biomedical Research, University of Genova, Genova, Italy.

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November 2011

LANCL2 is necessary for abscisic acid binding and signaling in human granulocytes and in rat insulinoma cells.

J Biol Chem 2009 Oct 10;284(41):28045-57. Epub 2009 Aug 10.

Department of Experimental Medicine, Section of Biochemistry, and Center of Excellence for Biomedical Research, University of Genova, Viale Benedetto XV 1, Genova 16132, Italy.

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October 2009

The cholinergic system and cancer.

Semin Cancer Biol 2008 Jun 23;18(3):211-7. Epub 2007 Dec 23.

Lung Cancer Unit, National Cancer Research Institute, Genova, Italy.

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June 2008

Commentary: early diagnosis of lung cancer: where do we stand?

Oncologist 2007 Dec;12(12):1433-6

Lung Cancer Unit, Department of Advanced Diagnostic Technology, National Cancer Research Institute, Largo Rosanna Benzi 10, I-16132, Genova, Italy.

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December 2007

Nicotine, lung and cancer.

Anticancer Agents Med Chem 2007 Jul;7(4):461-6

Translational Research B (Lung Cancer), Department of Integrated Medical Oncology (DOMI), National Cancer Institute, Largo Rosanna Benzi 10, Genoa, Italy.

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July 2007