Alessia Alunno

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Alessia Alunno

Publications by authors named "Alessia Alunno"

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83Publications

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The challenge to interpret conflicting results and the need of a univocal definition for germinal centres in primary Sjögren's syndrome.

Ann Rheum Dis 2018 Jun 10;77(6):e31. Epub 2017 Aug 10.

Department of Medicine, Rheumatology Unit, University of Perugia, Perugia, Italy.

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June 2018

One year in review 2018: pathogenesis of rheumatoid arthritis.

Clin Exp Rheumatol 2018 Mar-Apr;36(2):175-184. Epub 2018 Apr 18.

Rheumatology Unit, Department of Medicine, University of Perugia, Italy.

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June 2018

Missing pebble in the mosaic of rheumatic diseases and mental health: younger does not always mean happier.

Ann Rheum Dis 2018 Apr 28. Epub 2018 Apr 28.

Division of Rheumatology, Department of Internal Medicine 3, Medical University Vienna, Vienna, Austria.

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April 2018

Lymphoma and Lymphomagenesis in Primary Sjögren's Syndrome.

Front Med (Lausanne) 2018 13;5:102. Epub 2018 Apr 13.

Rheumatology Unit, Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, L'Aquila, Italy.

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April 2018

Umbilical cord mesenchymal stem cells for the treatment of autoimmune diseases: beware of cell-to-cell contact.

Ann Rheum Dis 2018 Mar 13;77(3):e14. Epub 2017 Jun 13.

Rheumatology Unit, Department of Medicine, University of Perugia, Perugia, Italy.

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March 2018

Hypertension as a cardiovascular risk factor in autoimmune rheumatic diseases.

Nat Rev Cardiol 2018 Jan 24;15(1):33-44. Epub 2017 Aug 24.

Rheumatology Unit, Department of Medicine, University of Perugia, P.le Menghini 1, Perugia 06129, Italy.

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January 2018

'Twitterland': a brave new world?

Ann Rheum Dis 2017 Dec 4. Epub 2017 Dec 4.

Department of Rheumatology, Inflammation-Immunopathology-Biotherapy Department, Pierre and Marie Curie University, Saint-Antoine hospital, Sorbonne University, Paris, France.

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December 2017

Clinical, Epidemiological, and Histopathological Features of Respiratory Involvement in Rheumatoid Arthritis.

Biomed Res Int 2017 7;2017:7915340. Epub 2017 Nov 7.

Rheumatology Unit, Department of Biotechnological and Applied Clinical Science, School of Medicine, University of L'Aquila, L'Aquila, Italy.

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November 2017

Novel Therapeutic Strategies in Primary Sjögren's Syndrome.

Isr Med Assoc J 2017 Sep;19(9):576-580

Rheumatology Unit, Department of Medicine, University of Perugia, Italy.

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September 2017

Correlation between ESSDAI and ClinESSDAI in a real-life cohort of patients with Sjögren's syndrome.

Clin Exp Rheumatol 2017 May-Jun;35(3):546-547. Epub 2017 Feb 10.

Rheumatology Clinic, Department of Medical and Biological Sciences, Azienda Ospedaliero-Universitaria 'S. Maria della Misericordia', Udine, Italy.

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August 2017

Cryoglobulinemia in Sjögren Syndrome: A Disease Subset that Links Higher Systemic Disease Activity, Autoimmunity, and Local B Cell Proliferation in Mucosa-associated Lymphoid Tissue.

J Rheumatol 2017 Aug 15;44(8):1179-1183. Epub 2017 May 15.

From the Rheumatology Clinic, Department of Medical and Biological Sciences, Azienda Ospedaliero-Universitaria S. Maria della Misericordia, Udine; Rheumatology Unit, Department of Internal Medicine, University of Pisa, Pisa; Rheumatology Unit, Sapienza University of Rome, Rome; Rheumatology Unit, Department of Clinical and Experimental Medicine, University of Perugia, Perugia; Rheumatology Unit, University of L'Aquila, L'Aquila, Italy.

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August 2017

One year in review 2017: pathogenesis of rheumatoid arthritis.

Clin Exp Rheumatol 2017 May-Jun;35(3):368-378. Epub 2017 Jun 7.

Immuno-Allergology Unit, Department of Clinical and Experimental Medicine, University of Pisa, Italy.

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August 2017

One year in review 2017: systemic lupus erythematosus.

Clin Exp Rheumatol 2017 Jul-Aug;35(4):551-561. Epub 2017 Jul 11.

Rheumatology Unit, Department of Clinical and Experimental Medicine, University of Pisa, Italy.

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August 2017

Anti -citrullinated peptide antibodies profiling in established rheumatoid arthritis.

Joint Bone Spine 2017 Aug 5. Epub 2017 Aug 5.

Clinical Immunology and Allergy Unit, Department of Clinical and Experimental Medicine, University of Pisa, Via Roma 67, 56126 Pisa, Italy. Electronic address:

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August 2017

Patient-physician collaboration in rheumatology: a necessity.

RMD Open 2017 18;3(1):e000499. Epub 2017 Jul 18.

Division of Clinical Rheumatology, Department of Internal Medicine, University of Genoa, Genoa, Italy.

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July 2017

Persistence of focal lymphocytic sialadenitis in patients with primary Sjögren's syndrome treated with rituximab: a possible role for glandular BAFF.

Clin Exp Rheumatol 2016 Nov-Dec;34(6):1123-1124. Epub 2016 Aug 2.

Department of Biotechnological and Applied Clinical Sciences, Rheumatology Unit, University of L'Aquila, Italy.

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June 2017

Antioxidant and Immune System Regulatory Properties of Extracts.

Oxid Med Cell Longev 2017 13;2017:7468064. Epub 2017 Mar 13.

Rheumatology Unit, Department of Clinical and Experimental Medicine, University of Perugia, Perugia, Italy.

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May 2017

One year in review 2016: pathogenesis of rheumatoid arthritis.

Clin Exp Rheumatol 2016 Sep-Oct;34(5):793-801. Epub 2016 Sep 16.

Rheumatology Unit, Department of Medicine, University of Perugia, Italy.

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January 2017

Central Hemodynamics and Arterial Stiffness in Systemic Sclerosis.

Hypertension 2016 12 17;68(6):1504-1511. Epub 2016 Oct 17.

From the Rheumatology Unit, Department of Medicine, University of Perugia, Italy (E.B., G.P., F.C., F.B., A.A., M.G., G.C., R.G., G.S.); and Unit of Internal Medicine, Department of Medicine, Terni University Hospital, Italy (G.P., F.B., M.G., G.S.).

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December 2016

Targeting the IL-23/IL-17 axis for the treatment of psoriasis and psoriatic arthritis.

Expert Opin Biol Ther 2015 7;15(12):1727-37. Epub 2015 Sep 7.

a 1 University of Perugia, Department of Medicine , Perugia, Italy.

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July 2016

Mobilization of lymphatic endothelial precursor cells and lymphatic neovascularization in primary Sjögren's syndrome.

J Cell Mol Med 2016 Apr 1;20(4):613-22. Epub 2016 Feb 1.

Department of Experimental and Clinical Medicine, Section of Anatomy and Histology, University of Florence, Florence, Italy.

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April 2016

T Regulatory and T Helper 17 Cells in Primary Sjögren's Syndrome: Facts and Perspectives.

Mediators Inflamm 2015 28;2015:243723. Epub 2015 Apr 28.

Rheumatology Unit, Department of Medicine, University of Perugia, 06123 Perugia, Italy.

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February 2016

Restoration of t cell substes of patients with type 1 diabetes mellitus by microencapsulated human umbilical cord Wharton jelly-derived mesenchymal stem cells: An in vitro study.

Clin Immunol 2016 Feb 8;163:34-41. Epub 2015 Dec 8.

Department of Medicine, Section of Cardiovascular, Endocrine and Metabolic Clinical Physiology, Laboratory for Endocrine Cell Transplants and Biohybrid Organs, University of Perugia, Piazzale Gambuli, Perugia, Italy. Electronic address:

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February 2016

Anti-SSA/SSB-negative Sjögren's syndrome shows a lower prevalence of lymphoproliferative manifestations, and a lower risk of lymphoma evolution.

Autoimmun Rev 2015 Nov 8;14(11):1019-22. Epub 2015 Jul 8.

Rheumatology Clinic, Department of Medical and Biological Sciences, Azienda Ospedaliero-Universitaria "S. Maria della Misericordia", Udine, Italy. Electronic address:

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November 2015

One year in review: the pathogenesis of rheumatoid arthritis.

Clin Exp Rheumatol 2015 Jul-Aug;33(4):551-8. Epub 2015 Jul 21.

Rheumatology Unit, Department of Medicine, University of Perugia, Perugia, Italy.

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October 2015

Correlation between clinimetric approach and German US7 score in rheumatoid arthritis patients treated with tocilizumab: a pilot study.

Clin Exp Rheumatol 2015 May-Jun;33(3):445. Epub 2015 Apr 28.

Rheumatology Unit, Department of Medicine, University of Perugia, Italy.

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August 2015

Telocytes in minor salivary glands of primary Sjögren's syndrome: association with the extent of inflammation and ectopic lymphoid neogenesis.

J Cell Mol Med 2015 Jul 6;19(7):1689-96. Epub 2015 Mar 6.

Department of Experimental and Clinical Medicine, Section of Anatomy and Histology, University of Florence, Florence, Italy.

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July 2015

Serum interleukin-17 in primary Sjögren's syndrome: association with disease duration and parotid gland swelling.

Clin Exp Rheumatol 2015 Jan-Feb;33(1):129. Epub 2014 Dec 22.

Rheumatology Unit, Department of Medicine, University of Perugia, Perugia, Italy.

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April 2015

GITR+ regulatory T cells in the treatment of autoimmune diseases.

Autoimmun Rev 2015 Feb 14;14(2):117-26. Epub 2014 Oct 14.

Department of Medicine, Section of Pharmacology, University of Perugia, Italy.

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February 2015

In vitro immunomodulatory effects of microencapsulated umbilical cord Wharton jelly-derived mesenchymal stem cells in primary Sjögren's syndrome.

Rheumatology (Oxford) 2015 Jan 26;54(1):163-8. Epub 2014 Jul 26.

Rheumatology Unit, Department of Medicine, Laboratory for the Study and Transplant of Pancreatic Islets (LSTPI) and Department of Internal Medicine, University of Perugia, Perugia, Italy.

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January 2015

Cardiovascular disease in systemic sclerosis.

Ann Transl Med 2015 Jan;3(1)

Department of Medicine, Rheumatology Unit, University of Perugia, Via dal Pozzo 06132, Perugia, Italy.

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January 2015

Unmasking the pathogenic role of IL-17 axis in primary Sjögren's syndrome: a new era for therapeutic targeting?

Autoimmun Rev 2014 Dec 23;13(12):1167-73. Epub 2014 Aug 23.

Rheumatology Unit, Department of Medicine, University of Perugia, Italy. Electronic address:

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December 2014

Drugs in induction and treatment of idiopathic inflammatory myopathies.

Auto Immun Highlights 2014 Dec 19;5(3):95-100. Epub 2014 Oct 19.

Rheumatology Unit, Division of Rheumatology, Department of Medicine-DIMED, University of Padova, Via Giustiniani, 2, 35128 Padua, Italy.

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December 2014

The role of T helper 17 cell subsets in Sjögren's syndrome: similarities and differences between mouse model and humans.

Ann Rheum Dis 2014 Jul 27;73(7):e42. Epub 2014 Mar 27.

Rheumatology Unit, Department of Medicine, University of Perugia, Perugia, Italy.

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July 2014

CD4(-)CD8(-) T-cells in primary Sjögren's syndrome: association with the extent of glandular involvement.

J Autoimmun 2014 Jun 24;51:38-43. Epub 2014 Jan 24.

Rheumatology Unit, Department of Medicine, University of Perugia, Via Enrico Dal Pozzo, s.n.c., Perugia I-06126, Italy. Electronic address:

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June 2014

Diagnosis and classification of autoimmune hypophysitis.

Autoimmun Rev 2014 Apr-May;13(4-5):412-6. Epub 2014 Jan 13.

Rheumatology Unit, Department of Medicine, University of Perugia, Perugia, Italy. Electronic address:

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May 2014

Indoleamine 2,3-dioxygenase 1 (IDO1) is up-regulated in thyroid carcinoma and drives the development of an immunosuppressant tumor microenvironment.

J Clin Endocrinol Metab 2014 May 11;99(5):E832-40. Epub 2014 Feb 11.

Departments of Internal Medicine (S.Moret., E.M., P.V., S.Morel., S.C., V.B., E.P.), Experimental Medicine and Biochemical Sciences (R.C., F.F., C.O., M.G.M., P.P.), Clinical and Experimental Medicine (A.A., R.G.), Chemistry and Drug Technology (A.M.), and Surgery (N.A.), University of Perugia, 06132 Perugia, Italy; Research Centre of Thyroid Proteomics and Genomics (S.Moret., E.M., P.V., S.Morel., N.A., E.P.), University of Perugia, 05100 Terni, Italy; Department of Clinical Sciences (M.S., S.F.), University of Rome "Sapienza," 00161 Rome, Italy; Department of Medicine (D.d.B., G.T.), Anatomic Pathology Unit, Bellaria Hospital, University of Bologna, 40139 Bologna, Italy; and Department of Molecular Medicine and Biotechnological Sciences (R.M.M., M.S.), University of Naples "Federico II," 80138 Naples, Italy.

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May 2014

Large aortic pseudoaneurysm and subsequent spondylodiscitis as a complication of endovascular treatment of iliac arteries.

Thorac Cardiovasc Surg 2013 Oct 5;61(7):606-9. Epub 2013 Apr 5.

Division of Vascular Surgery, Department of Surgery and Transplant "P. Stefanini," Sapienza University of Rome, Rome, Italy.

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October 2013

Characterization of a new regulatory CD4+ T cell subset in primary Sjögren's syndrome.

Rheumatology (Oxford) 2013 Aug 14;52(8):1387-96. Epub 2013 May 14.

Rheumatology Unit, Department of Clinical and Experimental Medicine, University of Perugia, Via Enrico Dal Pozzo, I-06122 Perugia, Italy.

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August 2013

The microbial capsular polysaccharide galactoxylomannan inhibits IL-17A production in circulating T cells from rheumatoid arthritis patients.

PLoS One 2013 8;8(1):e53336. Epub 2013 Jan 8.

Microbiology Section, Department of Experimental Medicine and Biochemical Science, University of Perugia, Perugia, Italy.

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July 2013

Cardiovascular risk in rheumatoid arthritis and systemic autoimmune rheumatic disorders: a suggested model of preventive strategy.

Clin Rev Allergy Immunol 2013 Feb;44(1):14-22

Rheumatology Unit, Department of Clinical and Experimental Medicine, University of Perugia, Via Enrico Dal Pozzo, 06122 Perugia, Italy.

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February 2013

IL-17-producing CD4-CD8- T cells are expanded in the peripheral blood, infiltrate salivary glands and are resistant to corticosteroids in patients with primary Sjogren's syndrome.

Ann Rheum Dis 2013 Feb 17;72(2):286-92. Epub 2012 Aug 17.

Rheumatology Unit, Department of Clinical & Experimental Medicine, University of Perugia, Via Enrico Dal Pozzo, Perugia I-06122, Italy.

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February 2013

Persistent type II endoleak: two cases of successful sacotomy.

Ann Vasc Surg 2013 Feb;27(2):240.e9-240.e11

Department of Surgery and Transplant P. Stefanini, Division of Vascular Surgery, Sapienza University of Rome, Rome, Italy.

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February 2013

Balance between regulatory T and Th17 cells in systemic lupus erythematosus: the old and the new.

Clin Dev Immunol 2012 14;2012:823085. Epub 2012 Jun 14.

Rheumatology Unit, Department of Clinical and Experimental Medicine, University of Perugia, Via Enrico dal Pozzo, 06122 Perugia, Italy.

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October 2012

Aortic stiffness is increased in polymyalgia rheumatica and improves after steroid treatment.

Ann Rheum Dis 2012 Jul 20;71(7):1151-6. Epub 2012 Jan 20.

Medicina Interna, Angiologia e Malattie da Arteriosclerosi, Università degli Studi di Perugia, Ospedale S. Maria della Misericordia piazzale G. Menghini, 1-06129 Perugia, Italy.

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July 2012

Type IB and type III endoleak 8 years after endovascular aneurysm repair.

J Vasc Surg 2012 Mar;55(3):848

Department of Vascular Surgery, Policlinico Umberto I-Sapienza University, Rome, Italy.

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March 2012

Carotid stenting and transcranial Doppler monitoring: indications for carotid stenosis treatment.

Vasc Endovascular Surg 2010 Oct 30;44(7):535-8. Epub 2010 Jul 30.

Department of Vascular Surgery A, Sapienza University, Rome, Italy.

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October 2010

Atherosclerotic vascular damage and rheumatoid arthritis: a complex but intriguing link.

Expert Rev Cardiovasc Ther 2010 Sep;8(9):1309-16

Rheumatology Unit, Department of Clinical & Experimental Medicine, University of Perugia, Perugia 06100, Italy.

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September 2010

How early is the atherosclerotic risk in rheumatoid arthritis?

Autoimmun Rev 2010 Aug 11;9(10):701-7. Epub 2010 Jun 11.

Department of Clinical & Experimental Medicine, University of Perugia, Italy.

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August 2010

Role of regulatory T cells in rheumatoid arthritis: facts and hypothesis.

Auto Immun Highlights 2010 May 10;1(1):45-51. Epub 2010 Jul 10.

Rheumatology Unit, Department of Clinical and Experimental Medicine, University of Perugia, via E. dal Pozzo, Perugia, I-06122 Italy.

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May 2010

Identification of regulatory T cells in systemic lupus erythematosus.

Autoimmun Rev 2009 Mar 8;8(5):426-30. Epub 2009 Feb 8.

Rheumatology Unit, Department of Clinical & Experimental Medicine, University of Perugia, Perugia, Italy.

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March 2009

Management of simultaneous abdominal aortic aneurysm and colorectal cancer: the rationale of mini-invasive approach.

Surg Oncol 2007 Dec 26;16 Suppl 1:S165-7. Epub 2007 Nov 26.

Vascular Surgery-Department of Surgery, University of Insubria-Varese, Ospedale di Circolo, 21100 via Guicciardini 9, Varese, Italy.

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December 2007

Accelerated atherosclerosis in systemic lupus erythematosus and other connective tissue diseases.

Expert Rev Clin Immunol 2007 Jul;3(4):531-41

University of Perugia, Rheumatology Unit, Department of Clinical & Experimental Medicine, Policlinico Monteluce, I-06122 Perugia, Italy.

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July 2007