Publications by authors named "Alessandro Severo Alves de Melo"

22 Publications

  • Page 1 of 1

Diagnostic imaging in bronchial atresia.

Radiol Bras 2021 Mar-Apr;54(2)

Universidade Federal Fluminense (UFF), Niterói, RJ, Brazil. Email:

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http://dx.doi.org/10.1590/0100-3984.2021.54.2e1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8029932PMC
April 2021

Imaging contribution for the diagnosis of disseminated paracoccidioidomycosis.

Int J Infect Dis 2020 12 5;101:206-209. Epub 2020 Oct 5.

Department of Radiology, Federal Fluminense University, Avenida Marquês de Paraná, 303, Niterói, 24033-900, RJ, Brazil.

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http://dx.doi.org/10.1016/j.ijid.2020.09.1482DOI Listing
December 2020

Bilateral medullary infarct: the radiologist's point of view.

Neuroradiology 2021 01 5;63(1):15-16. Epub 2020 Sep 5.

Department of Radiology, Federal Fluminense University, Avenida Marquês de Paraná, 303, Niteroi, RJ, 24033-900, Brazil.

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http://dx.doi.org/10.1007/s00234-020-02544-3DOI Listing
January 2021

Neurofibromatosis type 1: State-of-the-art review with emphasis on pulmonary involvement.

Respir Med 2019 03 17;149:9-15. Epub 2019 Jan 17.

Federal University of Rio de Janeiro, Rio de Janeiro, Brazil. Electronic address:

Neurofibromatosis type 1 (NF-1), also known as von Recklinghausen's disease, is an autosomal dominant dysplasia of the ectoderm and mesoderm with a variable clinical expression, but near-complete penetrance before the age of 5 years. The estimated incidence is 1 in 3000 births. NF-1 is characterized by collections of neurofibromas, café-au-lait spots, axillary and inguinal freckling, and pigmented hamartomas in the iris (Lisch nodules). Pulmonary manifestations of NF-1, which usually include bilateral basal reticulations and apical bullae and cysts, are reported in 10-20% of adult patients. Clinically, neurofibromatosis-associated diffuse lung disease (NF-DLD) usually presents with nonspecific respiratory symptoms, including dyspnea on exertion, shortness of breath, and chronic cough or chest pain, at the time of diagnosis. Computed tomography (CT) is highly accurate for the identification and characterization of NF-DLD; it is the most reliable method for the diagnosis of this lung involvement. Various CT findings of NF-DLD, including cysts, bullae, ground-glass opacities, bibasilar reticular opacities, and emphysema, have been described in patients with NF-1. The typical CT pattern, however, is characterized by upper-lobe cystic and bullous disease, and basilar interstitial lung disease. Currently, the goal of NF-DLD treatment is the earliest possible diagnosis, focusing on symptom relief and interventions that positively alter the course of the disease, such as smoking cessation. The aim of this review is to describe the main clinical, pathological, and imaging aspects of NF-1, with a focus on pulmonary involvement.
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http://dx.doi.org/10.1016/j.rmed.2019.01.002DOI Listing
March 2019

Acute Q fever pneumonia: high-resolution computed tomographic findings in six patients.

Br J Radiol 2019 Mar 4;92(1095):20180292. Epub 2019 Jan 4.

2 Department of Radiology, Federal University of Rio de Janeiro , Rio de Janeiro , Brazil.

Methods:: We analyzed high-resolution CT (HRCT) findings from six male patients (mean age, 22.6 years) with confirmed diagnoses of acute Q fever. Two chest radiologists analyzed the images and reached decisions by consensus. All patients presented fever, myalgia, prostation, headache, and dry cough. They also had common epidemiologic factors (recent travel for military service, where they had contact with sheep and capybara). Diagnoses were confirmed by the detection of C. burnetii DNA in clinical samples by polymerase chain reaction.

Results:: The predominant HRCT findings were areas of consolidation (100%) and nodules (66.6%) with halos of ground-glass opacity, predominantly with segmental and peripheral distributions. Lesions affected all lobes, and predominated in the left upper and lower lobes. Involvement of more than one lobe was observed in four patients. No pleural effusion or lymph node enlargement was found.

Conclusion:: The predominant HRCT findings in patients with acute Q fever pneumonia were bilateral, peripheral areas of consolidation and nodules with irregular contours and halos of ground-glass opacity.

Advances In Knowledge:: Acute Q fever should be included in the differential diagnosis of lesions with the halo sign on HRCT.
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http://dx.doi.org/10.1259/bjr.20180292DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6541175PMC
March 2019

Systemic paracoccidioidomycosis involving breast.

Breast J 2018 09 22;24(5):831-832. Epub 2018 Jul 22.

Department of Radiology, "Antonio Pedro" University Hospital, Fluminense Federal University, Niterói, Rio de Janeiro, Brazil.

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http://dx.doi.org/10.1111/tbj.13078DOI Listing
September 2018

Tomographic aspects of penetrating thoracic trauma: injuries from firearms and other weapons.

Radiol Bras 2017 Nov-Dec;50(6):372-377

Full Professor at the Universidade Federal do Rio de Janeiro (UFRJ), Rio de Janeiro, RJ, Brazil.

Objective: The aim of this study was to analyze the various computed tomography findings in penetrating chest trauma, as well as to determine the frequency and extent of the lesions.

Material And Methods: We studied the computed tomography findings from 40 cases of penetrating thoracic trauma, of which 35 (85.8%) were gunshot wounds and 5 (14.2%) were caused by another type of weapon.

Results: Pulmonary lesions were found in 39 cases (97.5%), manifesting as contusions in 34 cases (85%), atelectasis in 8 (20%), lacerations in 1 (2.5%) and hematomas in 1 (2.5%). Hemothorax was seen in 31 cases (77.5%), and pneumothorax was seen in 22 cases (55%). Mediastinal lesions were observed in 8 cases (20%), including mediastinal hematoma in 3 cases (7.5%), hemopericardium in 3 (7.5%), and pneumomediastinum in 2 (5%). Diaphragmatic rupture was seen in 2 cases (5%).

Conclusion: In patients with penetrating thoracic trauma, computed tomography of the chest is an important tool for characterizing the affected organs and evaluating the path of injury, as well as the severity and extent of the lesions. The images obtained are also useful in estimating the risk of death and determining the best therapeutic approach.
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http://dx.doi.org/10.1590/0100-3984.2016.0167DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5746881PMC
January 2018

Ogilvie syndrome after use of vincristine: tomographic findings.

Radiol Bras 2017 Jul-Aug;50(4):273-274

Hospital Universitário Antonio Pedro - Universidade Federal Fluminense (HUAP-UFF), Niterói, RJ, Brazil.

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http://dx.doi.org/10.1590/0100-3984.2015.0162DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5586525PMC
September 2017

Brain Infarct and Abscess-A Very Common Disease and a Rare Association.

World Neurosurg 2016 09;93:476

Rede Dor -Sa/O Luiz, Radiologia, Rio de Janeiro, Brazil.

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http://dx.doi.org/10.1016/j.wneu.2016.05.098DOI Listing
September 2016

Prolactinomas may have unusual presentations resulting from massive extrasellar tumor extension.

Arq Neuropsiquiatr 2016 Jul;74(7):544-8

Universidade Federal Fluminense, Hospital Universitário Antônio Pedro, Unidade de Endocrinologia, Niterói RJ, Brasil;

The purpose of this case series is to report eight patients with giant prolactinomas emphasizing presentations and a treatment complication. The study group included six men and two women. The median age was 29 years (18-54 years); median serum prolactin level was 4,562 ng/ml (1,543-18,690 ng/ml); three patients (37.5%) had panhypopituitarism; median tumor diameter was 50 mm (41-60 mm). Five patients (62.5%) had visual field defects and three had improvement during treatment; six patients (75%) reached prolactin normalization, with a median time of 10.5 months (7-84 months) and median dose of 2.0 mg/week (1.0 to 3.0 mg/week). One patient presented as a true incidentaloma. One patient presented a cerebrospinal fluid leakage during medical treatment and refused surgery, however this resolved with conservative measures. This case series illustrate a rare subtype of macroprolactinomas, the importance of considering unusual presentations at the diagnosis, the effectiveness of pharmacological treatment and its possible complications.
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http://dx.doi.org/10.1590/0004-282X20160083DOI Listing
July 2016

Applications of Magnetic Resonance Imaging of the Thorax in Pleural Diseases: A State-of-the-Art Review.

Lung 2016 08 14;194(4):501-9. Epub 2016 Jun 14.

Federal University of Rio de Janeiro, Rua Thomaz Cameron, 438. Valparaiso, Rio De Janeiro, Petrópolis, CEP 25685.120, Brazil.

The aim of this review was to present the main aspects of pleural diseases seen with conventional and advanced magnetic resonance imaging (MRI) techniques. This modality is considered to be the gold standard for the evaluation of the pleural interface, characterization of complex pleural effusion, and identification of exudate and hemorrhage, as well as in the analysis of superior sulcus tumors, as it enables more accurate staging. The indication for MRI of the thorax in the identification of these conditions is increasing in comparison to computerized tomography, and it can also be used to support the diagnosis of pulmonary illnesses. This literature review describes the morphological and functional aspects of the main benign and malignant pleural diseases assessed with MRI, including mesothelioma, metastasis, lymphoma, fibroma, lipoma, endometriosis, asbestos-related pleural disease, empyema, textiloma, and splenosis.
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http://dx.doi.org/10.1007/s00408-016-9909-9DOI Listing
August 2016

Cutaneous invasion from sarcomatoid urothelial carcinoma: clinical and dermatopathologic features.

An Bras Dermatol 2016 Jan-Feb;91(1):73-9

Rio de Janeiro, Rio de Janeiro, RJ, Brazil.

In Brazil, without considering the non-melanoma skin tumors, bladder cancer in men is the eighth most common, and the urothelial carcinoma or transitional cell carcinoma is the most common among these. Cutaneous metastases from urothelial neoplasms appear as single or multiple erythematous, infiltrated nodules or plaques, and like other cases of distant disease, it is indicative of poor prognosis. The invasive urothelial carcinoma is recognized for its ability to present divergent differentiation and morphological variants. The sarcomatoid urothelial carcinoma is a rare cancer that consists of two different components: one composed of epithelial tissue and the other with sarcomatoid features of mesenchymal origin. The authors describe a case of cutaneous metastasis of sarcomatoid urothelial carcinoma in a 63-year-old male patient.
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http://dx.doi.org/10.1590/abd1806-4841.20164081DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4782650PMC
October 2016

[Traumatic chest lesions. Computed tomography findings].

Rev Port Pneumol 2004 Sep-Oct;10(5):393-403

Serviço de Radiologia, Hospital Municipal Souza Aguilar, Rio de Janeiro, Brazil.

Trauma is nowadays one of the most common causes of death and traumatic thoracic lesions are important agravant to trauma patients. In this work the aspects of computed tomography from 200 cases of thoracic trauma were studied. Lung lesions predominated, found in 192 cases (96%), manifested as contusions in 178 cases (89%), atelectasis in 41 cases (20.5%), lacerations in 15 cases (7.5%) and hematomas in 6 cases (3%). Pleural lesions were showed in 140 cases (70%), among them in 121 cases (60.5%) there were hemothorax and in 84 cases (42%), pneumothorax. Mediastinal lesions were observed in 28 cases (14%), with pneumomediastinum in 18 cases (9%), mediastinal hematoma in 7 cases (3.5%), hemopericardium in 4 cases (2%) and aortic lesions in 3 cases (1.5%). Diaphragmatic rupture was seen in 8 patients (4%). Soft tissue emphysema was demonstrated in 36 cases (18%).
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February 2005
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