Publications by authors named "Alessandro Rosa"

55Publications

The Aurora-A/TPX2 Axis Directs Spindle Orientation in Adherent Human Cells by Regulating NuMA and Microtubule Stability.

Curr Biol 2020 Nov 25. Epub 2020 Nov 25.

Institute of Molecular Biology and Pathology, National Research Council of Italy, c/o Department of Biology and Biotechnology, Sapienza University of Rome, Via degli Apuli 4, 00185 Rome, Italy. Electronic address:

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November 2020

UV-C Irradiation as a Tool to Reduce Biofilm Growth on Pompeii Wall Paintings.

Int J Environ Res Public Health 2020 11 13;17(22). Epub 2020 Nov 13.

Department of Humanities, University of Naples Suor Orsola Benincasa, 80132 Naples, Italy.

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November 2020

Identification of Molecular Signatures in Neural Differentiation and Neurological Diseases Using Digital Color-Coded Molecular Barcoding.

Stem Cells Int 2020 12;2020:8852313. Epub 2020 Sep 12.

Center for Life Nano Science, Istituto Italiano di Tecnologia, Rome 00161, Italy.

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September 2020

Drug discontinuation in pregnant women with psoriasis: The PSO-MOTHER cohort study.

Pharmacoepidemiol Drug Saf 2020 08 5;29(8):904-912. Epub 2020 Jun 5.

Department of Epidemiology, Lazio Regional Health Service, Rome, Italy.

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August 2020

Acute conversion of patient-derived Duchenne muscular dystrophy iPSC into myotubes reveals constitutive and inducible over-activation of TGFβ-dependent pro-fibrotic signaling.

Skelet Muscle 2020 05 2;10(1):13. Epub 2020 May 2.

Epigenetics and Cell Fate (EDC), Centre National de la Recherche Scientifique (CNRS), Université Paris Diderot, Université de Paris, F-75013, Paris, France.

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May 2020

Excess TPX2 Interferes with Microtubule Disassembly and Nuclei Reformation at Mitotic Exit.

Cells 2020 02 6;9(2). Epub 2020 Feb 6.

Institute of Molecular Biology and Pathology, National Research Council of Italy, c/o Sapienza University of Rome, Via degli Apuli 4, 00185 Rome, Italy.

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February 2020

Inducible SMARCAL1 knockdown in iPSC reveals a link between replication stress and altered expression of master differentiation genes.

Dis Model Mech 2019 10 17;12(10). Epub 2019 Oct 17.

Mechanisms, Biomarkers and Models Unit, Department of Environment and Health, Istituto Superiore di Sanità, Viale Regina Elena 299, 00161 Rome, Italy

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October 2019

Construction of 3D in vitro models by bioprinting human pluripotent stem cells: Challenges and opportunities.

Brain Res 2019 11 16;1723:146393. Epub 2019 Aug 16.

Department of Biology and Biotechnology Charles Darwin, Sapienza University of Rome, P.le A. Moro 5, 00185 Rome, Italy; Center for Life Nano Science, Istituto Italiano di Tecnologia, Viale Regina Elena 291, 00161 Rome, Italy. Electronic address:

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November 2019

Mutant FUS and ELAVL4 (HuD) Aberrant Crosstalk in Amyotrophic Lateral Sclerosis.

Cell Rep 2019 06;27(13):3818-3831.e5

Center for Life Nano Science, Istituto Italiano di Tecnologia, Viale Regina Elena 291, 00161 Rome, Italy; Department of Biology and Biotechnology Charles Darwin, Sapienza University of Rome, P.le A. Moro 5, 00185 Rome, Italy. Electronic address:

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June 2019

Conversion of Human Induced Pluripotent Stem Cells (iPSCs) into Functional Spinal and Cranial Motor Neurons Using PiggyBac Vectors.

J Vis Exp 2019 05 1(147). Epub 2019 May 1.

Department of Biology and Biotechnology Charles Darwin, Sapienza University of Rome, Italy; Center for Life Nano Science, Istituto Italiano di Tecnologia, Italy;

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May 2019

Immunological profiles of HIV-positive recipients of liver transplant.

Transpl Immunol 2019 12 15;57:101208. Epub 2019 May 15.

Infectious Diseases Division, Santa Maria della Misericordia University Hospital, Udine, Italy.

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December 2019

Background-deflection Brillouin microscopy reveals altered biomechanics of intracellular stress granules by ALS protein FUS.

Commun Biol 2018 10;1:139. Epub 2018 Sep 10.

Center for Life Nano Science@Sapienza, Istituto Italiano di Tecnologia, Rome, Italy.

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September 2018

Antimicrobial resistance and treatment: an unmet clinical safety need.

Expert Opin Drug Saf 2018 07 22;17(7):669-680. Epub 2018 Jun 22.

a Infectious Diseases Division , Santa Maria Misericordia Hospital , Udine , Italy.

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July 2018

Direct conversion of human pluripotent stem cells into cranial motor neurons using a piggyBac vector.

Stem Cell Res 2018 05 27;29:189-196. Epub 2018 Apr 27.

Center for Life Nano Science, Istituto Italiano di Tecnologia, Viale Regina Elena 291, 00161 Rome, Italy; Department of Biology and Biotechnology Charles Darwin, Sapienza University of Rome, P.le A. Moro 5, 00185 Rome, Italy. Electronic address:

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May 2018

FUS Mutant Human Motoneurons Display Altered Transcriptome and microRNA Pathways with Implications for ALS Pathogenesis.

Stem Cell Reports 2017 11 5;9(5):1450-1462. Epub 2017 Oct 5.

Center for Life Nano Science, Istituto Italiano di Tecnologia, Viale Regina Elena 291, 00161 Rome, Italy; Department of Biology and Biotechnology Charles Darwin, Sapienza University of Rome, P.le A. Moro 5, 00185 Rome, Italy. Electronic address:

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November 2017

Importin-β and CRM1 control a RANBP2 spatiotemporal switch essential for mitotic kinetochore function.

J Cell Sci 2017 Aug 9;130(15):2564-2578. Epub 2017 Jun 9.

CNR National Research Council of Italy, Institute of Molecular Biology and Pathology (IBPM), ℅ Department of Biology and Biotechnology, Sapienza Università di Roma, Via degli Apuli 4, 00185 Rome, Italy

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August 2017

Role of MicroRNAs in Zygotic Genome Activation: Modulation of mRNA During Embryogenesis.

Methods Mol Biol 2017 ;1605:31-43

Laboratory of Molecular Vertebrate Embryology, The Rockefeller University, 1230 York Ave., New York, NY, 10065, USA.

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February 2018

Divergent lncRNAs take the lead on pluripotent cell differentiation.

Stem Cell Investig 2016 19;3:47. Epub 2016 Sep 19.

Department of Biology and Biotechnology Charles Darwin, Sapienza University of Rome, P.le A. Moro 5, 00185 Rome, Italy.

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September 2016

Differentiation of control and ALS mutant human iPSCs into functional skeletal muscle cells, a tool for the study of neuromuscolar diseases.

Stem Cell Res 2016 07 8;17(1):140-7. Epub 2016 Jun 8.

Department of Biology and Biotechnology Charles Darwin, Sapienza University of Rome, P.le A. Moro 5, 00185 Rome, Italy. Electronic address:

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July 2016

Long Noncoding RNA Regulation of Pluripotency.

Stem Cells Int 2016 30;2016:1797692. Epub 2015 Nov 30.

Department of Biology and Biotechnology Charles Darwin, Sapienza University of Rome, 00185 Rome, Italy ; Institute Pasteur Fondazione Cenci-Bolognetti, Sapienza University of Rome, 00185 Rome, Italy.

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December 2015

ALS mutant FUS proteins are recruited into stress granules in induced pluripotent stem cell-derived motoneurons.

Dis Model Mech 2015 Jul 23;8(7):755-66. Epub 2015 Apr 23.

Center for Life Nano Science, Istituto Italiano di Tecnologia, Viale Regina Elena 291, Rome 00161, Italy Department of Biology and Biotechnology Charles Darwin, Sapienza University of Rome, P.le A. Moro 5, Rome 00185, Italy Institute Pasteur Fondazione Cenci-Bolognetti, Sapienza University of Rome, P.le A. Moro 5, Rome 00185, Italy

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July 2015

Enriched environment reduces glioma growth through immune and non-immune mechanisms in mice.

Nat Commun 2015 Mar 30;6:6623. Epub 2015 Mar 30.

1] Department of Physiology and Pharmacology, Istituto Pasteur-Fondazione Cenci Bolognetti Sapienza University, Piazzale Aldo Moro 5, 00185 Rome, Italy [2] IRCCS Neuromed, Via Atinense 18, 86077 Pozzilli, IS, Italy.

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March 2015

miR-373 is regulated by TGFβ signaling and promotes mesendoderm differentiation in human Embryonic Stem Cells.

Dev Biol 2014 Jul 4;391(1):81-8. Epub 2014 Apr 4.

Laboratory of Molecular Vertebrate Embryology, The Rockefeller University, New York, NY 10065, USA. Electronic address:

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July 2014

High frequency ultrasound for in vivo pregnancy diagnosis and staging of placental and fetal development in mice.

PLoS One 2013 14;8(10):e77205. Epub 2013 Oct 14.

Dipartimento di Scienze Biomediche Avanzate, Università degli studi di Napoli Federico II, Napoli, Italy ; IRCCS Fondazione SDN, Napoli, Italy.

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June 2014

Regulatory non-coding RNAs in pluripotent stem cells.

Int J Mol Sci 2013 Jul 11;14(7):14346-73. Epub 2013 Jul 11.

Department of Biology and Biotechnology Charles Darwin, Sapienza University of Rome, Rome 00185, Italy.

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July 2013

In vitro release and expansion of mesenchymal stem cells by a hyaluronic acid scaffold used in combination with bone marrow.

Muscles Ligaments Tendons J 2012 Oct 21;2(4):289-94. Epub 2013 Jan 21.

Department of Orthopaedics and Traumatology, San Camillo Hospital, Rome, Italy.

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October 2012

Non coding RNA in muscle differentiation and disease.

Microrna 2013 ;2(2):91-101

Dept. of Biology and Biotechnology "Charles Darwin", Sapienza University of Rome, P.le A. Moro 5, 00185 Rome - Italy.

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April 2018

A regulatory circuitry comprised of miR-302 and the transcription factors OCT4 and NR2F2 regulates human embryonic stem cell differentiation.

EMBO J 2011 Jan 10;30(2):237-48. Epub 2010 Dec 10.

Laboratory of Molecular Vertebrate Embryology, The Rockefeller University, New York, NY, USA.

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January 2011

Synthetic mRNAs: powerful tools for reprogramming and differentiation of human cells.

Cell Stem Cell 2010 Nov;7(5):549-50

Laboratory of Molecular Vertebrate Embryology, The Rockefeller University, New York, NY 10065, USA.

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November 2010

APOBEC2, a selective inhibitor of TGFβ signaling, regulates left-right axis specification during early embryogenesis.

Dev Biol 2011 Feb 27;350(1):13-23. Epub 2010 Sep 27.

Laboratory of Vertebrate Embryology, The Rockefeller University, 1230 York Ave., New York, NY 10065, USA.

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February 2011

MicroRNAs in early vertebrate development.

Cell Cycle 2009 Nov 18;8(21):3513-20. Epub 2009 Nov 18.

Laboratory of Molecular Vertebrate Embryology, The Rockefeller University, New York, NY, USA.

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November 2009

The miR-430/427/302 family controls mesendodermal fate specification via species-specific target selection.

Dev Cell 2009 Apr;16(4):517-27

Laboratory of Molecular Vertebrate Embryology, The Rockefeller University, New York, NY 10065, USA.

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April 2009

Role of microRNAs in myeloid differentiation.

Biochem Soc Trans 2008 Dec;36(Pt 6):1201-5

Department of Genetics, Institute Pasteur Cenci-Bolognetti, Sapienza University, Rome, Italy.

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December 2008

Body-wide gene therapy of Duchenne muscular dystrophy in the mdx mouse model.

Proc Natl Acad Sci U S A 2006 Mar 24;103(10):3758-63. Epub 2006 Feb 24.

Institute Pasteur Cenci-Bolognetti, Department of Genetics and Molecular Biology, University La Sapienza, P. le Aldo Moro 5, 00185 Rome, Italy.

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March 2006

A minicircuitry comprised of microRNA-223 and transcription factors NFI-A and C/EBPalpha regulates human granulopoiesis.

Cell 2005 Dec;123(5):819-31

Department of Histology and Medical Embryology, University of Rome La Sapienza and San Raffaele Biomedical Science Park of Rome, Via di Castel Romano 100, 00128, Rome, Italy.

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December 2005

A new vector, based on the PolII promoter of the U1 snRNA gene, for the expression of siRNAs in mammalian cells.

Mol Ther 2004 Jul;10(1):191-9

Istituto Pasteur-Fondazione Centi-Bolognetti, Department of Genetics and Molecular Biology, University of Rome La Sapienza and IBPM of CNR, Rome, Italy.

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July 2004