Publications by authors named "Alessandro Martorana"

83Publications

Effects of Cerebellar Theta Burst Stimulation on Contralateral Motor Cortex Excitability in Patients with Alzheimer's Disease.

Brain Topogr 2020 09 20;33(5):613-617. Epub 2020 Jun 20.

Non-invasive Brain Stimulation Unit, Department of Behavioural and Clinical Neurology, Santa Lucia Foundation IRCCS, Via Ardeatina 306, 00179, Rome, Italy.

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http://dx.doi.org/10.1007/s10548-020-00781-6DOI Listing
September 2020

LTP-like cortical plasticity predicts conversion to dementia in patients with memory impairment.

Brain Stimul 2020 Sep - Oct;13(5):1175-1182. Epub 2020 May 30.

Non Invasive Brain Stimulation Unit/Department of Behavioral and Clinical Neurology, Santa Lucia Foundation IRCCS, Rome, Italy; Section of Human Physiology, ECampus University, Novedrate, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.brs.2020.05.013DOI Listing
May 2020

The Brain Metabolic Correlates of the Main Indices of Neuropsychological Assessment in Alzheimer's Disease.

J Pers Med 2020 Apr 18;10(2). Epub 2020 Apr 18.

Department of Biomedicine and Prevention, University Tor Vergata, 00133 Rome, Italy.

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http://dx.doi.org/10.3390/jpm10020025DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7354489PMC
April 2020

The role of epsilon phenotype in brain glucose consumption in Alzheimer's disease.

Ann Nucl Med 2020 Apr 3;34(4):254-262. Epub 2020 Feb 3.

Department of Biomedicine and Prevention, Faculty of Medicine and Surgery, Tor Vergata University, Rome, Italy.

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http://dx.doi.org/10.1007/s12149-020-01441-2DOI Listing
April 2020

Transcranial magnetic stimulation: Emerging biomarkers and novel therapeutics in Alzheimer's disease.

Neurosci Lett 2020 02 28;719:134355. Epub 2019 Jun 28.

Non Invasive Brain Stimulation Unit/Department of Behavioral and Clinical Neurology, Santa Lucia Foundation IRCCS, Rome, Italy.

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http://dx.doi.org/10.1016/j.neulet.2019.134355DOI Listing
February 2020

Brain metabolic patterns in patients with suspected non-Alzheimer's pathophysiology (SNAP) and Alzheimer's disease (AD): is [F] FDG a specific biomarker in these patients?

Eur J Nucl Med Mol Imaging 2019 Aug 14;46(9):1796-1805. Epub 2019 Jun 14.

Department of Biomedicine and Prevention, University Tor Vergata, Viale Oxford 81, 00133, Rome, Italy.

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http://dx.doi.org/10.1007/s00259-019-04379-4DOI Listing
August 2019

Transcranial magnetic stimulation predicts cognitive decline in patients with Alzheimer's disease.

J Neurol Neurosurg Psychiatry 2018 12 21;89(12):1237-1242. Epub 2018 Jul 21.

Non Invasive Brain Stimulation Unit, Department of Behavioral and Clinical Neurology, Santa Lucia Foundation IRCCS, Rome, Italy

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http://dx.doi.org/10.1136/jnnp-2017-317879DOI Listing
December 2018

Impaired Spike Timing Dependent Cortico-Cortical Plasticity in Alzheimer's Disease Patients.

J Alzheimers Dis 2018 ;66(3):983-991

Department of Behavioural and Clinical Neurology, Non-invasive Brain Stimulation Unit, Santa Lucia Foundation IRCCS, Rome, Italy.

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http://dx.doi.org/10.3233/JAD-180503DOI Listing
November 2019

LTP-like cortical plasticity is associated with verbal memory impairment in Alzheimer's disease patients.

Brain Stimul 2019 Jan - Feb;12(1):148-151. Epub 2018 Oct 19.

Non Invasive Brain Stimulation Unit/Department of Behavioral and Clinical Neurology, Santa Lucia Foundation IRCCS, Rome, Italy; Stroke Unit, Tor Vergata Policlinic, Rome, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.brs.2018.10.009DOI Listing
May 2019

Lacosamide in the Management of Behavioral Symptoms in Frontotemporal Dementia: A 2-Case Report.

Alzheimer Dis Assoc Disord 2018 Oct-Dec;32(4):364-365

Department of Systems Medicine, University of Rome Tor Vergata.

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http://dx.doi.org/10.1097/WAD.0000000000000245DOI Listing
September 2019

Transcranial magnetic stimulation of the precuneus enhances memory and neural activity in prodromal Alzheimer's disease.

Neuroimage 2018 04 19;169:302-311. Epub 2017 Dec 19.

Neuroimaging Laboratory, Santa Lucia Foundation, IRCCS, Rome, 00179, Italy; Department of Neuroscience, Brighton and Sussex Medical School, University of Sussex, Brighton BN1 9RR, East Sussex, UK. Electronic address:

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http://dx.doi.org/10.1016/j.neuroimage.2017.12.048DOI Listing
April 2018

Brain metabolic correlates of CSF Tau protein in a large cohort of Alzheimer's disease patients: A CSF and FDG PET study.

Brain Res 2018 Jan 21;1678:116-122. Epub 2017 Oct 21.

Department of Biomedicine and Prevention, University Tor Vergata, Rome, Italy; IRCCS Neuromed, Pozzilli, Italy.

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http://dx.doi.org/10.1016/j.brainres.2017.10.016DOI Listing
January 2018

Levels of amyloid-beta-42 and CSF pressure are directly related in patients with Alzheimer's disease.

J Neural Transm (Vienna) 2017 12 2;124(12):1621-1625. Epub 2017 Sep 2.

Neurology Unit, Department of Systems Medicine, University of Roma Tor Vergata, Via Montpellier 1, 00133, Rome, Italy.

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http://dx.doi.org/10.1007/s00702-017-1786-8DOI Listing
December 2017

Transcranial magnetic stimulation distinguishes Alzheimer disease from frontotemporal dementia.

Neurology 2017 Aug 26;89(7):665-672. Epub 2017 Jul 26.

From the Neurology Unit (A.B., V.D., M.C., A.A., S.C., L.R., A.P., B.B.), Department of Clinical and Experimental Sciences, University of Brescia; Non-Invasive Brain Stimulation Unit (F.D.L., V.P., A. Martorana, C.C., G.K.), IRCCS Santa Lucia Foundation; Stroke Unit (G.K.), Policlinico Tor Vergata, Rome; Neurology Unit (M.S.C.), Valle Camonica Hospital, Brescia; Casa di Cura San Francesco (A. Micheli), Bergamo; Dipartimento di ingegneria dell'Informazione (A.D., A.F.), University of Brescia; and Neurology Unit (A. Martorana, C.C.), Department of System Medicine, University of Tor Vergata, Rome, Italy.

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http://dx.doi.org/10.1212/WNL.0000000000004232DOI Listing
August 2017

Assessment of serum uric acid as risk factor for tauopathies.

J Neural Transm (Vienna) 2017 09 15;124(9):1105-1108. Epub 2017 Jun 15.

Neurology Unit, Department of Systems Medicine, University of Roma Tor Vergata, Via Montpellier 1, 00133, Rome, Italy.

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http://dx.doi.org/10.1007/s00702-017-1743-6DOI Listing
September 2017

Alzheimer's Disease and the Routine Clinical Use of CSF Biomarkers.

CNS Neurol Disord Drug Targets 2017 ;16(4):407-413

System Medicine Department, University of Rome "Tor Vergata", Via Montpellier, 1-00133-Rome, Italy.

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http://dx.doi.org/10.2174/1871527316666170124164854DOI Listing
April 2018

Is cerebral glucose metabolism related to blood-brain barrier dysfunction and intrathecal IgG synthesis in Alzheimer disease?: A 18F-FDG PET/CT study.

Medicine (Baltimore) 2016 09;95(37):e4206

aDepartment of Biomedicine and Prevention, University Tor Vergata, Rome, Italy bIRCCS Neuromed, Pozzilli, Italy cDepartment of Health Sciences, University Magna Graecia, Catanzaro, Italy dDepartment of Neurosciences, University Tor Vergata, Rome, Italy eIRCCS Santa Lucia, Rome, Italy.

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http://dx.doi.org/10.1097/MD.0000000000004206DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5402543PMC
September 2016

Editorial (Thematic Issue: Old Facts and New Perspectives to Face Alzheimer's Dementia. Focus on Non Neuronal Participants to Neurodegeneration).

CNS Neurol Disord Drug Targets 2016 ;15(6):646

Clinica Neurologica, Dipartimento di Medicina Sperimentale e Clinica, Università Politecnica delle Marche, Ancona, Italy.

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http://dx.doi.org/10.2174/1871527315999160606154409DOI Listing
January 2018

Long-term potentiation-like cortical plasticity is disrupted in Alzheimer's disease patients independently from age of onset.

Ann Neurol 2016 08 8;80(2):202-10. Epub 2016 Jul 8.

Non Invasive Brain Stimulation Unit/Department of Behavioral and Clinical Neurology, Santa Lucia Foundation IRCCS, Rome, Italy.

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http://dx.doi.org/10.1002/ana.24695DOI Listing
August 2016

Insulin and the Future Treatment of Alzheimer's Disease.

CNS Neurol Disord Drug Targets 2016 ;15(6):660-4

Centro Alzheimer- UOC Neurologia, Dipartimento Medicina dei Sistemi-Università di Roma Tor Vergata.

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http://dx.doi.org/10.2174/1871527315666160518123049DOI Listing
October 2017

Cerebrospinal Fluid Aβ42 Levels: When Physiological Become Pathological State.

CNS Neurosci Ther 2015 Dec 11;21(12):921-5. Epub 2015 Nov 11.

Non-Invasive Brain Stimulation Unit, Department of Behavioral and Clinical Neurology, Santa Lucia Foundation IRCCS, Rome, Italy.

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http://dx.doi.org/10.1111/cns.12476DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6493161PMC
December 2015

A clinical and biochemical analysis in the differential diagnosis of idiopathic normal pressure hydrocephalus.

Front Neurol 2015 23;6:86. Epub 2015 Apr 23.

Department of Systems Medicine, University of Rome "Tor Vergata" , Rome , Italy ; IRCCS Santa Lucia Foundation , Rome , Italy.

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http://dx.doi.org/10.3389/fneur.2015.00086DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4407581PMC
May 2015

Functional correlates of t-Tau, p-Tau and Aβ₁₋₄₂ amyloid cerebrospinal fluid levels in Alzheimer's disease: a ¹⁸F-FDG PET/CT study.

Nucl Med Commun 2015 May;36(5):461-8

Departments of aBiomedicine and Prevention bNeurosciences, University Tor Vergata, Rome cIRCCS Neuromed, Pozzilli, Italy.

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http://dx.doi.org/10.1097/MNM.0000000000000272DOI Listing
May 2015

"Is dopamine involved in Alzheimer's disease?".

Front Aging Neurosci 2014 25;6:252. Epub 2014 Sep 25.

Clinica Neurologica-Memory Clinic, System Medicine Department, Università di Roma "Tor Vergata" Rome, Italy ; Non Invasive Brain Stimulation Unit, Department of Behavioral and Clinical Neurology, Santa Lucia Foundation IRCCS Rome, Italy.

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http://dx.doi.org/10.3389/fnagi.2014.00252DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4174765PMC
October 2014

Homotaurine induces measurable changes of short latency afferent inhibition in a group of mild cognitive impairment individuals.

Front Aging Neurosci 2014 23;6:254. Epub 2014 Sep 23.

Non-Invasive Brain Stimulation Unit, Department of Behavioral and Clinical Neurology, Santa Lucia Foundation IRCCS , Rome , Italy.

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http://dx.doi.org/10.3389/fnagi.2014.00254DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4172065PMC
October 2014

Dopaminergic modulation of cortical plasticity in Alzheimer's disease patients.

Neuropsychopharmacology 2014 Oct 26;39(11):2654-61. Epub 2014 May 26.

Department of Neuroscience, Tor Vergata University, Rome, Italy.

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http://dx.doi.org/10.1038/npp.2014.119DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4207345PMC
October 2014

Alzheimer's disease and frail syndrome: features overlap predictive of poor outcome.

CNS Neurol Disord Drug Targets 2013 Jun;12(4):506

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http://dx.doi.org/10.2174/18715273113129990068DOI Listing
June 2013

Amyloid β, glutamate, excitotoxicity in Alzheimer's disease: are we on the right track?

CNS Neurosci Ther 2013 Aug 18;19(8):549-55. Epub 2013 Apr 18.

Centro per il Decadimento Cognitivo, Sacro Cuore Don Calabria, Negrar-Verona, Italy.

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http://dx.doi.org/10.1111/cns.12095DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6493397PMC
August 2013

Ageing as a Trait de Union between diabetes and dementia for frailty.

CNS Neurol Disord Drug Targets 2013 Jun;12(4):520-4

ACISMOM Centro Diabetologico- Via LE Morselli, 13 00148 Roma, Italy.

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http://dx.doi.org/10.2174/1871527311312040012DOI Listing
June 2013

Frailty among Alzheimer's disease patients.

CNS Neurol Disord Drug Targets 2013 Jun;12(4):507-11

Department of Neuroscience, University of Rome Tor Vergata, 1 Montpellier Street-00133-Rome, Italy.

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http://dx.doi.org/10.2174/1871527311312040010DOI Listing
June 2013

Dopamine D₂-agonist rotigotine effects on cortical excitability and central cholinergic transmission in Alzheimer's disease patients.

Neuropharmacology 2013 Jan 1;64:108-13. Epub 2012 Aug 1.

Clinica Neurologica, Dipartimento di Neuroscienze, Centro di Riferimento per la Malattia di Alzheimer, Università di Roma Tor Vergata, Viale Oxford 81, 00133 Roma, Italy.

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http://dx.doi.org/10.1016/j.neuropharm.2012.07.015DOI Listing
January 2013

CSF and clinical hallmarks of subcortical dementias: focus on DLB and PDD.

J Neural Transm (Vienna) 2012 Jul 24;119(7):861-75. Epub 2012 May 24.

Dipartimento di Neuroscienze, Università di Roma Tor Vergata, Rome, Italy.

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http://dx.doi.org/10.1007/s00702-012-0820-0DOI Listing
July 2012

Apathy as marker of frail status.

J Aging Res 2012 12;2012:436251. Epub 2012 Feb 12.

Clinica Neurologica, Dipartimento di Neuroscienze, Università di Roma "Tor Vergata", Via Montpellier, 00133 Rome, Italy.

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http://dx.doi.org/10.1155/2012/436251DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3303535PMC
August 2012

Plasmin system of Alzheimer's disease patients: CSF analysis.

J Neural Transm (Vienna) 2012 Jul 14;119(7):763-9. Epub 2012 Mar 14.

Department of Neuroscience, University of Rome Tor Vergata, 1 Montpellier Street, 00133, Rome, Italy.

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http://dx.doi.org/10.1007/s00702-012-0778-yDOI Listing
July 2012

CSF tau levels influence cortical plasticity in Alzheimer's disease patients.

J Alzheimers Dis 2011 ;26(1):181-6

Dipartimento di Neuroscienze, Policlinico Tor Vergata, Universitá di Roma Tor Vergata, Rome, Italy.

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http://dx.doi.org/10.3233/JAD-2011-110116DOI Listing
January 2012

Altered dopamine modulation of LTD-like plasticity in Alzheimer's disease patients.

Clin Neurophysiol 2011 Apr 13;122(4):703-7. Epub 2010 Nov 13.

Stroke Unit, Dipartimento di Neuroscienze, Università di Roma Tor Vergata, Rome, Italy.

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http://dx.doi.org/10.1016/j.clinph.2010.10.033DOI Listing
April 2011

Beyond the cholinergic hypothesis: do current drugs work in Alzheimer's disease?

CNS Neurosci Ther 2010 Aug 16;16(4):235-45. Epub 2010 Apr 16.

Clinica Neurologica, Dipartimento di Neuroscienze, Università di Roma "Tor Vergata", Rome, Italy.

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http://dx.doi.org/10.1111/j.1755-5949.2010.00175.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6493875PMC
August 2010

Dopamine modulates cholinergic cortical excitability in Alzheimer's disease patients.

Neuropsychopharmacology 2009 Sep 10;34(10):2323-8. Epub 2009 Jun 10.

Clinica Neurologica, Dipartimento di Neuroscienze, Università di Roma Tor Vergata, Roma, Italy.

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http://dx.doi.org/10.1038/npp.2009.60DOI Listing
September 2009

Effects of simvastatin on neuroprotection and modulation of Bcl-2 and BAX in the rat quinolinic acid model of Huntington's disease.

Neurosci Lett 2008 Dec 14;448(1):166-9. Epub 2008 Oct 14.

Laboratory of Neuroanatomy, Santa Lucia Foundation IRCCS, European Center for Brain Research, Rome, Italy.

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http://dx.doi.org/10.1016/j.neulet.2008.10.023DOI Listing
December 2008

L-dopa modulates motor cortex excitability in Alzheimer's disease patients.

J Neural Transm (Vienna) 2008 Sep 2;115(9):1313-9. Epub 2008 Jul 2.

Dipartimento di Neuroscienze, Clinica Neurologica, Università di Roma, "Tor Vergata", via Montpellier, 1, 00133 Rome, Italy,

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http://dx.doi.org/10.1007/s00702-008-0082-zDOI Listing
September 2008

In vivo electrophysiology of dopamine-denervated striatum: focus on the nitric oxide/cGMP signaling pathway.

Synapse 2008 Jun;62(6):409-20

Division of Neurology, Department of Neuroscience, University of Rome Tor Vergata, Rome, Italy.

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http://dx.doi.org/10.1002/syn.20510DOI Listing
June 2008

Adult polyglucosan body disease: proton magnetic resonance spectroscopy of the brain and novel mutation in the GBE1 gene.

Muscle Nerve 2008 Apr;37(4):530-6

Dipartimento di Neuroscienze, Università di Roma Tor Vergata and Fondazione Santa Lucia, Roma, Italy.

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http://dx.doi.org/10.1002/mus.20916DOI Listing
April 2008

Beneficial effects of rolipram in a quinolinic acid model of striatal excitotoxicity.

Neurobiol Dis 2007 Feb 20;25(2):266-73. Epub 2006 Dec 20.

Laboratory of Neuroanatomy, Santa Lucia Foundation IRCCS at the European Center for Brain Research, via del Fosso Fiorano 64, 00143 Rome, Italy.

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http://linkinghub.elsevier.com/retrieve/pii/S096999610600236
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http://dx.doi.org/10.1016/j.nbd.2006.09.006DOI Listing
February 2007

Distribution of TRPC1 receptors in dendrites of rat substantia nigra: a confocal and electron microscopy study.

Eur J Neurosci 2006 Aug;24(3):732-8

Santa Lucia Foundation IRCCS Hospital, Laboratory of Neuroanatomy, Via del Fosso Fiorano 64, Rome, Italy.

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http://dx.doi.org/10.1111/j.1460-9568.2006.04932.xDOI Listing
August 2006

Striatal modulation of cAMP-response-element-binding protein (CREB) after excitotoxic lesions: implications with neuronal vulnerability in Huntington's disease.

Eur J Neurosci 2006 Jan;23(1):11-20

Laboratory of Neuroanatomy, Santa Lucia Foundation IRCCS at the European Center for Brain Research, via del Fosso Fiorano 64, 00143 Rome, Italy.

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http://dx.doi.org/10.1111/j.1460-9568.2005.04545.xDOI Listing
January 2006

Kyphoplasty: a new opportunity for rehabilitation of neurologic disabilities.

Am J Phys Med Rehabil 2004 Oct;83(10):810-2

Department of Diagnostics for Images and Interventional Radiology, University of Rome Tor Vergata, Policlinico Tor Vergata General Hospital, Rome, Italy.

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http://dx.doi.org/10.1097/01.phm.0000137319.22908.ebDOI Listing
October 2004

Cellular localization of TRPC3 channel in rat brain: preferential distribution to oligodendrocytes.

Neurosci Lett 2004 Jul;365(2):137-42

Laboratory of Experimental Neurorehabilitation, Basal Ganglia Section, Santa Lucia Foundation I.R.C.C.S, Via Ardeatina 306, 00179 Rome, Italy.

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http://dx.doi.org/10.1016/j.neulet.2004.04.070DOI Listing
July 2004

Co-localization of brain-derived neurotrophic factor (BDNF) and wild-type huntingtin in normal and quinolinic acid-lesioned rat brain.

Eur J Neurosci 2003 Sep;18(5):1093-102

Basal Ganglia Unit, Laboratory of Experimental Neurorehabilitation, Santa Lucia Foundation IRCCS, Via Ardeatina 306, Rome 00179, Italy.

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http://dx.doi.org/10.1046/j.1460-9568.2003.02844.xDOI Listing
September 2003

Huntingtin distribution among striatal output neurons of normal rat brain.

Neurosci Lett 2003 Mar;339(1):53-6

Laboratory of Experimental Neurorehabilitation, Santa Lucia Foundation IRCCS, Via Ardeatina 306, 00179, Rome, Italy.

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http://dx.doi.org/10.1016/s0304-3940(02)01474-xDOI Listing
March 2003

Tissue plasminogen activator is required for corticostriatal long-term potentiation.

Eur J Neurosci 2002 Aug;16(4):713-21

Clinica Neurologica, Dipartimento di Neuroscienze, Università di Tor Vergata, Via Montpellier 1, 00133 Rome, Italy.

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http://dx.doi.org/10.1046/j.1460-9568.2002.02106.xDOI Listing
August 2002