Alessandra Sacco

Alessandra Sacco

UNVERIFIED PROFILE

Are you Alessandra Sacco?   Register this Author

Register author
Alessandra Sacco

Alessandra Sacco

Publications by authors named "Alessandra Sacco"

Are you Alessandra Sacco?   Register this Author

43Publications

824Reads

47Profile Views

Tumorsphere Derivation and Treatment from Primary Tumor Cells Isolated from Mouse Rhabdomyosarcomas.

J Vis Exp 2019 Sep 13(151). Epub 2019 Sep 13.

Development, Aging and Regeneration Program, Sanford Burnham Prebys Medical Discovery Institute;

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3791/59897DOI Listing
September 2019

The Stat3-Fam3a axis promotes muscle stem cell myogenic lineage progression by inducing mitochondrial respiration.

Nat Commun 2019 04 17;10(1):1796. Epub 2019 Apr 17.

Development, Aging and Regeneration Program, Sanford Burnham Prebys Medical Discovery Institute, 10901N Torrey Pines Road, La Jolla, CA, 92037, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41467-019-09746-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6470137PMC
April 2019

Assessing Muscle Stem Cell Clonal Complexity During Aging.

Methods Mol Biol 2019 ;2045:1-11

Development, Aging and Regeneration Program, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/7651_2018_139DOI Listing
January 2019

The role of circulating free DNA in the management of NSCLC.

Expert Rev Anticancer Ther 2019 01 29;19(1):19-28. Epub 2018 Nov 29.

a Cell Biology and Biotherapy Unit , Istituto Nazionale Tumori, IRCSS, Fondazione G. Pascale , Napoli , Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/14737140.2019.1548938DOI Listing
January 2019

Muscle Stem Cells Give Rise to Rhabdomyosarcomas in a Severe Mouse Model of Duchenne Muscular Dystrophy.

Cell Rep 2019 01;26(3):689-701.e6

Development, Aging and Regeneration Program, Sanford Burnham Prebys Medical Discovery Institute, 10901 N. Torrey Pines Road, La Jolla, CA 92037, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.celrep.2018.12.089DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6853774PMC
January 2019

Engraftment of FACS Isolated Muscle Stem Cells into Injured Skeletal Muscle.

Methods Mol Biol 2017 ;1556:223-236

Development, Aging and Regeneration Program, Sanford Children's Health Research Center, Sanford-Burnham-Prebys Medical Discovery Institute, 10901 N Torrey Pines Rd, La Jolla, CA, 92037, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/978-1-4939-6771-1_11DOI Listing
February 2018

Inducing and Evaluating Skeletal Muscle Injury by Notexin and Barium Chloride.

Methods Mol Biol 2016 ;1460:53-60

Development, Aging and Regeneration Program, Sanford Children's Health Research Center, Sanford Burnham Prebys Medical Discovery Institute, 10901 North Torrey Pines Road, La Jolla, CA, 92037, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/978-1-4939-3810-0_5DOI Listing
January 2018

Muscle Stem Cells Exhibit Distinct Clonal Dynamics in Response to Tissue Repair and Homeostatic Aging.

Cell Stem Cell 2018 01 14;22(1):119-127.e3. Epub 2017 Dec 14.

Development, Aging and Regeneration Program, Sanford Burnham Prebys Medical Discovery Institute, 10901 N. Torrey Pines Road, La Jolla, CA 92037, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.stem.2017.11.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5945549PMC
January 2018

Single Stem Cell Imaging and Analysis Reveals Telomere Length Differences in Diseased Human and Mouse Skeletal Muscles.

Stem Cell Reports 2017 10 7;9(4):1328-1341. Epub 2017 Sep 7.

Department of Orthopaedic Surgery, Perelman School of Medicine, The University of Pennsylvania, 112A Stemmler Hall, 3450 Hamilton Walk, Philadelphia, PA 19104-6081, USA; Department of Cell and Developmental Biology, Perelman School of Medicine, The University of Pennsylvania, Philadelphia, PA 19104, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.stemcr.2017.08.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5639167PMC
October 2017

Engineering an Injectable Muscle-Specific Microenvironment for Improved Cell Delivery Using a Nanofibrous Extracellular Matrix Hydrogel.

ACS Nano 2017 04 27;11(4):3851-3859. Epub 2017 Mar 27.

Department of Bioengineering and Sanford Consortium for Regenerative Medicine, University of California, San Diego , La Jolla, California 92037, United States.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/acsnano.7b00093DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5576867PMC
April 2017

Innervation of dystrophic muscle after muscle stem cell therapy.

Muscle Nerve 2016 10 17;54(4):763-8. Epub 2016 Aug 17.

Department of Rehabilitation Science, School of Public Health and Health Professions, Kimball Tower, 3435 Main Street, Buffalo, New York, 14214-3079, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/mus.25115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5224835PMC
October 2016

The role of muscle stem cell-niche interactions during aging.

Nat Med 2016 08;22(8):837-8

Development, Aging and Regeneration Program, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, California, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nm.4159DOI Listing
August 2016

Satellite Cell Heterogeneity in Skeletal Muscle Homeostasis.

Trends Cell Biol 2016 06 3;26(6):434-444. Epub 2016 Mar 3.

Development, Aging, and Regeneration Program, Sanford Burnham Prebys Medical Discovery Institute, 10901N Torrey Pines Rd, La Jolla, CA 92037, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.tcb.2016.02.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4877266PMC
June 2016

Signal transducer and activator of transcription 3 signaling as a potential target to treat muscle wasting diseases.

Curr Opin Clin Nutr Metab Care 2016 May;19(3):171-6

Development, Aging and Regeneration Program (DARe), Sanford Burnham Prebys Medical Discovery Institute, San Diego, California, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/MCO.0000000000000273DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4866604PMC
May 2016

Autonomous Extracellular Matrix Remodeling Controls a Progressive Adaptation in Muscle Stem Cell Regenerative Capacity during Development.

Cell Rep 2016 Mar 18;14(8):1940-52. Epub 2016 Feb 18.

Development, Aging and Regeneration Program, Sanford Burnham Prebys Medical Discovery Institute, 10901 N. Torrey Pines Road, La Jolla, CA 92037, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.celrep.2016.01.072DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4778082PMC
March 2016

Combinations of Kinase Inhibitors Protecting Myoblasts against Hypoxia.

PLoS One 2015 4;10(6):e0126718. Epub 2015 Jun 4.

Sanford-Burnham Medical Research Institute, La Jolla, California, United States of America.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0126718PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4456388PMC
February 2016

EGFR mutations in lung cancer: from tissue testing to liquid biopsy.

Future Oncol 2015 ;11(11):1611-23

1Laboratory of Pharmacogenomics, Centro di Ricerche Oncologiche di Mercogliano (CROM)-Istituto Nazionale Tumori 'Fondazione G. Pascale'-IRCCS, Mercogliano (AV), Italy.

View Article

Download full-text PDF

Source
https://www.futuremedicine.com/doi/10.2217/fon.15.23
Publisher Site
http://dx.doi.org/10.2217/fon.15.23DOI Listing
February 2016

FACS-based Satellite Cell Isolation From Mouse Hind Limb Muscles.

Bio Protoc 2015 Aug;5(16)

Development, Aging and Regeneration Program, Sanford-Burnham Medical Research Institute, La Jolla, USA.

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5034768PMC
http://dx.doi.org/10.21769/bioprotoc.1558DOI Listing
August 2015

Regulation of Muscle Satellite Cell Function in Tissue Homeostasis and Aging.

Cell Stem Cell 2015 Jun;16(6):585-7

Development, Aging and Regeneration Program, Sanford-Burnham Medical Research Institute, 10901 North Torrey Pines Road, La Jolla, CA 92037, USA; Epigenetics and Regenerative Medicine, IRCCS Fondazione Santa Lucia, Via del Fosso di Fiorano 64, Rome, Italy. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.stem.2015.05.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4492457PMC
June 2015

STAT3 signaling controls satellite cell expansion and skeletal muscle repair.

Nat Med 2014 Oct 7;20(10):1182-6. Epub 2014 Sep 7.

Development, Aging and Regeneration Program (DARe), Sanford-Burnham Medical Research Institute, La Jolla, California, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nm.3656DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4332844PMC
October 2014

Directed in vitro myogenesis of human embryonic stem cells and their in vivo engraftment.

PLoS One 2013 19;8(8):e72023. Epub 2013 Aug 19.

Department of Bioengineering, University of California San Diego, San Diego, California, United States of America.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0072023PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3747108PMC
April 2014

Calpain-mediated proteolysis of tropomodulin isoforms leads to thin filament elongation in dystrophic skeletal muscle.

Mol Biol Cell 2014 Mar 15;25(6):852-65. Epub 2014 Jan 15.

Department of Cell and Molecular Biology, The Scripps Research Institute, La Jolla, CA 92037 Sanford Children's Health Research Center, Sanford-Burnham Medical Research Institute, La Jolla, CA 92037.

View Article

Download full-text PDF

Source
http://www.molbiolcell.org/doi/10.1091/mbc.e13-10-0608
Publisher Site
http://dx.doi.org/10.1091/mbc.E13-10-0608DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3952854PMC
March 2014

Short telomeres and stem cell exhaustion model Duchenne muscular dystrophy in mdx/mTR mice.

Cell 2010 Dec 9;143(7):1059-71. Epub 2010 Dec 9.

Baxter Laboratory for Stem Cell Biology, Department of Microbiology and Immunology, Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA.

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S00928674100136
Publisher Site
http://dx.doi.org/10.1016/j.cell.2010.11.039DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3025608PMC
December 2010

Reprogramming towards pluripotency requires AID-dependent DNA demethylation.

Nature 2010 Feb;463(7284):1042-7

Baxter Laboratory for Stem Cell Biology, Institute for Stem Cell Biology and Regenerative Medicine, Department of Microbiology and Immunology, Stanford University School of Medicine, Stanford, California 94305-5175, USA.

View Article

Download full-text PDF

Source
http://www.nature.com/articles/nature08752
Publisher Site
http://dx.doi.org/10.1038/nature08752DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2906123PMC
February 2010

A home away from home: challenges and opportunities in engineering in vitro muscle satellite cell niches.

Differentiation 2009 Sep-Oct;78(2-3):185-94

Baxter Laboratory in Genetic Pharmacology, Stanford University School of Medicine, Stanford, CA 94305, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.diff.2009.08.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2801624PMC
December 2009

Self-renewal and expansion of single transplanted muscle stem cells.

Nature 2008 Nov 17;456(7221):502-6. Epub 2008 Sep 17.

Baxter Laboratory in Genetic Pharmacology, Department of Microbiology and Immunology, Stem Cell Institute, Stanford University School of Medicine, Stanford, California 94305-5175, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nature07384DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2919355PMC
November 2008

IGF-I increases bone marrow contribution to adult skeletal muscle and enhances the fusion of myelomonocytic precursors.

J Cell Biol 2005 Nov;171(3):483-92

Department of Molecular Pharmacology, Baxter Laboratory in Genetic Pharmacology, Stanford University School of Medicine, Stanford, CA 94305, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1083/jcb.200506123DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2171272PMC
November 2005

Hematopoietic contribution to skeletal muscle regeneration by myelomonocytic precursors.

Proc Natl Acad Sci U S A 2004 Sep 7;101(37):13507-12. Epub 2004 Sep 7.

Baxter Laboratory in Genetic Pharmacology and Department of Molecular Pharmacology, Stanford University School of Medicine, 269 Campus Drive, Stanford, CA 94305, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1073/pnas.0405361101DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC518787PMC
September 2004

HPV E7 expression in skeletal muscle cells distinguishes initiation of the postmitotic state from its maintenance.

Oncogene 2003 Jun;22(26):4027-34

Laboratory of Comparative Toxicology and Ecotoxicology, Istituto Superiore di Sanita, Viale Regina Elena, 299, 00161 Rome, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/sj.onc.1206353DOI Listing
June 2003