Alejandro Sweet-Cordero

Alejandro Sweet-Cordero

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Alejandro Sweet-Cordero

Alejandro Sweet-Cordero

Publications by authors named "Alejandro Sweet-Cordero"

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43Publications

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The genomic landscape of pediatric cancers: Implications for diagnosis and treatment.

Science 2019 03;363(6432):1170-1175

Department of Pathology and Laboratory Medicine, Children's Hospital of Los Angeles, and Keck School of Medicine, University of Southern California, Los Angeles, CA 90027, USA.

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http://dx.doi.org/10.1126/science.aaw3535DOI Listing
March 2019

Oncogenic KRAS Regulates Amino Acid Homeostasis and Asparagine Biosynthesis via ATF4 and Alters Sensitivity to L-Asparaginase.

Cancer Cell 2018 01;33(1):91-107.e6

Division of Hematology and Oncology, Department of Pediatrics, Stanford University School of Medicine, Stanford, CA 94305, USA; Division of Hematology and Oncology, Department of Pediatrics, University of California San Francisco, San Francisco, CA 94158, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2017.12.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5761662PMC
January 2018

Improvement in treatment abandonment in pediatric patients with cancer in Guatemala.

Pediatr Blood Cancer 2017 Oct 19;64(10). Epub 2017 Apr 19.

Division of Hematology/Oncology, Department of Pediatrics, Stanford University School of Medicine, Palo Alto, California.

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http://dx.doi.org/10.1002/pbc.26560DOI Listing
October 2017

Statistical algorithms improve accuracy of gene fusion detection.

Nucleic Acids Res 2017 Jul;45(13):e126

Stanford University, Department of Biochemistry, 279 Campus Drive, Stanford, CA 94305, USA.

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http://dx.doi.org/10.1093/nar/gkx453DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5737606PMC
July 2017

The present and the future of the RAS pathway: From function and genomics to inhibition.

Cancer Biol Ther 2016 07 21;17(7):719-22. Epub 2016 May 21.

c Oncogenes and Metastasis Lab, Program in Solid Tumors and Biomarkers, Center for Applied Medical Research , Pamplona , Spain.

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http://dx.doi.org/10.1080/15384047.2016.1190487DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4970525PMC
July 2016

An Arntl2-Driven Secretome Enables Lung Adenocarcinoma Metastatic Self-Sufficiency.

Cancer Cell 2016 05 14;29(5):697-710. Epub 2016 Apr 14.

Department of Genetics, Stanford University School of Medicine, Stanford, CA 94305, USA; Department of Pathology, Stanford University School of Medicine, Stanford, CA 94305, USA; Cancer Biology Program, Stanford University School of Medicine, Stanford, CA 94305, USA; Stanford Cancer Institute, Stanford University School of Medicine, Stanford, CA 94305, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2016.03.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4864124PMC
May 2016

Preclinical Models Provide Scientific Justification and Translational Relevance for Moving Novel Therapeutics into Clinical Trials for Pediatric Cancer.

Cancer Res 2015 Dec 1;75(24):5176-5186. Epub 2015 Dec 1.

Department of Developmental Neurobiology, St. Jude Children's Research Hospital, Memphis, Tennessee, 38105, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-15-1308DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4681628PMC
December 2015

A meta-analysis of lung cancer gene expression identifies PTK7 as a survival gene in lung adenocarcinoma.

Cancer Res 2014 May 20;74(10):2892-902. Epub 2014 Mar 20.

Authors' Affiliations: Cancer Biology Program, Division of Hematology/Oncology, Department of Pediatrics; Center for Biomedical Informatics Research, Department of Medicine; Institute for Immunity, Transplant and Infection; Department of Cardiothoracic Surgery; and Division of Systems Medicine, Department of Pediatrics, Stanford University School of Medicine, Stanford, California

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http://cancerres.aacrjournals.org/cgi/doi/10.1158/0008-5472.
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http://dx.doi.org/10.1158/0008-5472.CAN-13-2775DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4084668PMC
May 2014

Mathematical modeling of tumor cell proliferation kinetics and label retention in a mouse model of lung cancer.

Cancer Res 2013 Jun 10;73(12):3525-33. Epub 2013 Apr 10.

Cancer Biology Program, Division of Hematology, Oncology, Stem Cell Transplantation and Cancer Biology, Department of Pediatrics, Pharsight Corp., Sunnyvale.

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http://dx.doi.org/10.1158/0008-5472.CAN-12-4244DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3703454PMC
June 2013

Two is better than one: combining IGF1R and MEK blockade as a promising novel treatment strategy against KRAS-mutant lung cancer.

Cancer Discov 2013 May;3(5):491-3

Department of Pediatrics, Stanford University School of Medicine, Stanford, CA, USA.

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http://dx.doi.org/10.1158/2159-8290.CD-13-0128DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6138247PMC
May 2013

The phosphatase PP2A links glutamine to the tumor suppressor p53.

Mol Cell 2013 Apr;50(2):157-8

Cancer Biology Program, Department of Pediatrics, Stanford University School of Medicine, Stanford, CA 94305, USA.

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http://dx.doi.org/10.1016/j.molcel.2013.04.010DOI Listing
April 2013

MEK1/2 inhibition elicits regression of autochthonous lung tumors induced by KRASG12D or BRAFV600E.

Cancer Res 2012 Jun 17;72(12):3048-59. Epub 2012 Apr 17.

Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco 94158, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-11-3649DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3393094PMC
June 2012

Discovery and preclinical validation of drug indications using compendia of public gene expression data.

Sci Transl Med 2011 Aug;3(96):96ra77

Division of Systems Medicine, Department of Pediatrics, Stanford University School of Medicine, 251 Campus Drive, Stanford, CA 94305-5415, USA.

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http://stm.sciencemag.org/cgi/doi/10.1126/scitranslmed.30013
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http://dx.doi.org/10.1126/scitranslmed.3001318DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3502016PMC
August 2011

New insights into oncogenic stress.

Nat Genet 2011 Mar;43(3):177-8

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http://dx.doi.org/10.1038/ng0311-177DOI Listing
March 2011

Wilms tumor 1 (WT1) regulates KRAS-driven oncogenesis and senescence in mouse and human models.

J Clin Invest 2010 Nov 25;120(11):3940-52. Epub 2010 Oct 25.

Cancer Biology Program, Department of Pediatrics, Stanford University School of Medicine, Stanford, California, USA.

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http://dx.doi.org/10.1172/JCI44165DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2965578PMC
November 2010

Expression and silencing of the microtubule-associated protein Tau in breast cancer cells.

Mol Cancer Ther 2010 Nov 9;9(11):2970-81. Epub 2010 Nov 9.

Department of Medicine, Stanford University School of Medicine, 269 Campus Drive, CCSR 1105, Stanford, CA 94305-5151, USA.

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http://dx.doi.org/10.1158/1535-7163.MCT-10-0780DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3065197PMC
November 2010

Hypoxia in models of lung cancer: implications for targeted therapeutics.

Clin Cancer Res 2010 Oct 21;16(19):4843-52. Epub 2010 Sep 21.

Department of Radiation Oncology, Stanford University, California 94305-5847, USA.

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http://dx.doi.org/10.1158/1078-0432.CCR-10-1206DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2948600PMC
October 2010

HIF-2alpha deletion promotes Kras-driven lung tumor development.

Proc Natl Acad Sci U S A 2010 Aug 21;107(32):14182-7. Epub 2010 Jul 21.

Abramson Family Cancer Research Institute, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA.

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http://www.pnas.org/cgi/doi/10.1073/pnas.1001296107
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http://dx.doi.org/10.1073/pnas.1001296107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2922515PMC
August 2010

New insights into tumor suppressors.

Genome Biol 2008 19;9(9):320. Epub 2008 Sep 19.

Department of Pediatrics, Stanford University, Stanford, CA 94305, USA.

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http://dx.doi.org/10.1186/gb-2008-9-9-320DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2592710PMC
January 2009

Comparison of gene expression and DNA copy number changes in a murine model of lung cancer.

Genes Chromosomes Cancer 2006 Apr;45(4):338-48

Massachusetts Institute of Technology, Center for Cancer Research, Cambridge, Massachusetts 02139, USA.

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http://dx.doi.org/10.1002/gcc.20296DOI Listing
April 2006

An oncogenic KRAS2 expression signature identified by cross-species gene-expression analysis.

Nat Genet 2005 Jan 19;37(1):48-55. Epub 2004 Dec 19.

MIT Center for Cancer Research, Building E17-517, 40 Ames Street, Cambridge, Massachusetts 02139, USA.

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http://dx.doi.org/10.1038/ng1490DOI Listing
January 2005