Publications by authors named "Alejandro Rodríguez Ogando"

7 Publications

  • Page 1 of 1

Microcirculatory Changes in Pediatric Patients During Congenital Heart Defect Corrective Surgery.

J Cardiovasc Transl Res 2021 May 4. Epub 2021 May 4.

Paediatric Intensive Care Unit, Gregorio Marañón General University Hospital, Calle Dr. Castelo 47, 28007, Madrid, Spain.

A prospective, observational single-center study was carried out. Pediatric patients undergoing congenital heart defect surgery were evaluated before, during, and after surgery. At each time point, sublingual microcirculation and clinical parameters were assessed, along with analytical variables. Twenty-four patients were included. All microcirculatory parameters worsened during cardiopulmonary bypass and returned to baseline values after surgery (p ≤ 0.001). In the intraoperative evaluation, body temperature correlated with perfused small vessel density (p = 0.014), proportion of perfused small vessels (p < 0.001), small vessel microvascular flow index (p = 0.003), and small vessel heterogeneity index (p < 0.002). Patients with cyanotic disease exhibited higher small vessel density (p < 0.008) and higher density of perfused small vessels (p < 0.022) at baseline, and a lower microvascular flow index (p = 0.022) and higher heterogeneity (p = 0.026) in the intraoperative phase. Children with congenital heart disease exhibited decreased vascular density and microvascular blood flow and increased heterogeneity during cardiopulmonary bypass. All these parameters returned to baseline values after surgery.
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http://dx.doi.org/10.1007/s12265-021-10132-wDOI Listing
May 2021

Selexipag use for paediatric pulmonary hypertension: a single centre report focussed on congenital heart disease patients.

Cardiol Young 2021 Mar 30:1-3. Epub 2021 Mar 30.

Pediatric Cardiology Section, "Gregorio Marañon" General University Hospital, Madrid, Spain.

Pulmonary hypertension is a rare and complex disease with poor prognosis. Paediatric cases are infrequent and usually associated with congenital heart disease. Management is problematical due to the limited therapy available and poor evidence of efficacy. Recently a new medication, selexipag (UptraviR), a prostacyclin receptor agonist, has been approved for the treatment of pulmonary artery hypertension in adults. We report our experience using selexipag in four paediatric patients with pulmonary hypertension associated with congenital heart disease.
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http://dx.doi.org/10.1017/S1047951121000937DOI Listing
March 2021

Experience With the Absorb Bioresorbable Vascular Scaffold in Various Scenarios of Congenital Heart Disease.

Rev Esp Cardiol (Engl Ed) 2018 Nov 5;71(11):988-990. Epub 2017 Oct 5.

Sección de Cardiología Pediátrica, Hospital General Universitario Gregorio Marañón, Madrid, Spain.

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http://dx.doi.org/10.1016/j.rec.2017.08.018DOI Listing
November 2018

Transcatheter Occlusion of Patent Ductus Arteriosus in Preterm Infants Weighing Less Than 2 kg With the Amplatzer Duct Occluder II Additional Sizes Device.

Rev Esp Cardiol (Engl Ed) 2018 Oct 12;71(10):865-866. Epub 2017 Sep 12.

Sección de Cardiología Pediátrica, Hospital General Universitario Gregorio Marañón, Madrid, Spain.

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http://dx.doi.org/10.1016/j.rec.2017.08.014DOI Listing
October 2018

Rare presentation of shock and acute mesenteric ischaemia secondary to acute adrenal insufficiency in an 11-year-old male.

J Paediatr Child Health 2013 Jun 13;49(6):498-500. Epub 2012 Sep 13.

Department of Pediatric Endocrinology, Hospital General Universitario Gregorio Marañón, Madrid, Spain.

An 11-year-old Caucasian male with history of abdominal pain, diarrhoea, fatigue, emesis and fever on the previous days presented with dehydratation, shock and acute mesenteric ischaemia. Final diagnosis of Addison's disease was made.
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http://dx.doi.org/10.1111/j.1440-1754.2012.02556.xDOI Listing
June 2013

Cystosarcoma phyllodes of the breast: a case report in a 12-year-old girl.

Clin Transl Oncol 2010 Oct;12(10):704-6

Department of Pediatrics, Hospital General Universitario Gregorio Marañón, Madrid, Spain.

Breast tumors in adolescents are very rare and mostly benign. Fibroadenomas are the most frequent, but within the extensive differential diagnosis, the phyllodes tumor must be mentioned, which accounts for about 1% of breast tumors and the diagnosis of which is very rare in patients younger than 20 years. There are no specific symptoms or radiological images to distinguish phyllodes tumor from fibroadenoma; therefore, histological examination is mandatory for diagnosis. Histology also allows the classification of phyllodes tumor into benign, borderline, or malignant types for appropriate surgical treatment: freemargin excision in benign tumors and mastectomy in the other two types. Fortunately, the majority of these tumors are benign, and treatment maximizes breast conservation with free infiltration margins surgery, given that this fact is the most important factor to prevent local recurrence. In this article, we describe a rare case of borderline cystosarcoma phyllodes in a 12-year-old girl.
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http://dx.doi.org/10.1007/s12094-010-0581-xDOI Listing
October 2010