Aldons J Lusis

Aldons J Lusis

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Aldons J Lusis

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Y-Chromosome Genetic Variation Associated With Atherosclerosis and Inflammation.

Authors:
Aldons J Lusis

Arterioscler Thromb Vasc Biol 2019 Nov 23;39(11):2201-2202. Epub 2019 Oct 23.

Department of Medicine/Division of Cardiology, Department of Human Genetics, Department of Microbiology, Immunology and Molecular Genetics, University of California, Los Angeles.

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http://dx.doi.org/10.1161/ATVBAHA.119.313369DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6818749PMC
November 2019

Proceedings of the 11th Congress of the International Society of Nutrigenetics and Nutrigenomics (ISNN 2017).

J Nutrigenet Nutrigenomics 2017 17;10(5-6):155-162. Epub 2018 Jan 17.

Departments of Human Genetics and Medicine, David Geffen School of Medicine of UCLA, Los Angeles, CA, USA.

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http://dx.doi.org/10.1159/000485799DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6490176PMC
September 2019

Targeting BCAA Catabolism to Treat Obesity-Associated Insulin Resistance.

Diabetes 2019 Sep 5;68(9):1730-1746. Epub 2019 Jun 5.

Department of Pathophysiology, Key Laboratory of Cell Differentiation and Apoptosis of the Chinese Ministry of Education, Hongqiao International Institute of Medicine, Shanghai Tongren Hospital/Faculty of Basic Medicine, Shanghai Jiao Tong University School of Medicine, Shanghai, China

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http://dx.doi.org/10.2337/db18-0927DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6702639PMC
September 2019

Diesel Exhaust Induces Mitochondrial Dysfunction, Hyperlipidemia, and Liver Steatosis.

Arterioscler Thromb Vasc Biol 2019 Sep 25;39(9):1776-1786. Epub 2019 Jul 25.

From the Division of Cardiology (F.Y., R.G., G.R., D.M.S., A.J.L., J.A.A.), David Geffen School of Medicine at University of California Los Angeles.

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http://dx.doi.org/10.1161/ATVBAHA.119.312736DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6703953PMC
September 2019

Diesel exhaust particles dysregulate multiple immunological pathways in murine macrophages: Lessons from microarray and scRNA-seq technologies.

Arch Biochem Biophys 2019 Sep 27:108116. Epub 2019 Sep 27.

Division of Cardiology, Department of Medicine, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA; Molecular Biology Institute, UCLA, Los Angeles, CA, USA; Department of Environmental Health Sciences, Fielding School of Public Health, UCLA, Los Angeles, CA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.abb.2019.108116DOI Listing
September 2019

Noggin depletion in adipocytes promotes obesity in mice.

Mol Metab 2019 Jul 10;25:50-63. Epub 2019 Apr 10.

Division of Cardiology, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095, USA; Molecular Biology Institute, UCLA, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S22128778183118
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http://dx.doi.org/10.1016/j.molmet.2019.04.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6600080PMC
July 2019

Isoproterenol-Induced Cardiac Diastolic Dysfunction in Mice: A Systems Genetics Analysis.

Front Cardiovasc Med 2019 31;6:100. Epub 2019 Jul 31.

Department of Medicine, University of California, Los Angeles, Los Angeles, CA, United States.

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http://dx.doi.org/10.3389/fcvm.2019.00100DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6684968PMC
July 2019

Targeted deletion of Tcf7l2 in adipocytes promotes adipocyte hypertrophy and impaired glucose metabolism.

Mol Metab 2019 Jun 14;24:44-63. Epub 2019 Mar 14.

Department of Biochemistry, University of Utah School of Medicine, Salt Lake City, UT, USA. Electronic address:

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http://dx.doi.org/10.1016/j.molmet.2019.03.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6531814PMC
June 2019

Contribution of Gene Regulatory Networks to Heritability of Coronary Artery Disease.

J Am Coll Cardiol 2019 Jun;73(23):2946-2957

Deutsches Herzzentrum München, Klinik für Herz- und Kreislauferkrankungen, Technische Universität München, DZHK (German Centre for Cardiovascular Research), Munich Heart Alliance, Munich, Germany; Integrated Cardio Metabolic Centre, Department of Medicine, Karolinska Institutet, Karolinska Universitetssjukhuset, Huddinge, Sweden; Department of Genetics & Genomic Sciences, Institute of Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, New York; Clinical Gene Networks AB, Stockholm, Sweden. Electronic address:

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http://dx.doi.org/10.1016/j.jacc.2019.03.520DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6590059PMC
June 2019

Gene-by-Sex Interactions in Mitochondrial Functions and Cardio-Metabolic Traits.

Cell Metab 2019 Apr 10;29(4):932-949.e4. Epub 2019 Jan 10.

Department of Medicine/Division of Cardiology and Department of Human Genetics, University of California, Los Angeles, Los Angeles, CA, USA; Department of Human Genetics, University of California, Los Angeles, Los Angeles, CA, USA; Department of Microbiology, Immunology and Molecular Genetics, University of California, Los Angeles, Los Angeles, CA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cmet.2018.12.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6447452PMC
April 2019

Systems-based approaches for investigation of inter-tissue communication.

J Lipid Res 2019 Mar 7;60(3):450-455. Epub 2019 Jan 7.

Departments of Medicine, University of California, Los Angeles, Los Angeles, CA 90095

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http://dx.doi.org/10.1194/jlr.S090316DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6399495PMC
March 2019

PON2 Deficiency Leads to Increased Susceptibility to Diet-Induced Obesity.

Antioxidants (Basel) 2019 Jan 11;8(1). Epub 2019 Jan 11.

Division of Cardiology, Department of Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA.

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http://dx.doi.org/10.3390/antiox8010019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6356528PMC
January 2019

Sex differences in metabolism and cardiometabolic disorders.

Curr Opin Lipidol 2018 10;29(5):404-410

Department of Medicine/Division of Cardiology.

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http://dx.doi.org/10.1097/MOL.0000000000000536DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6382080PMC
October 2018

A multi-tissue full lifespan epigenetic clock for mice.

Aging (Albany NY) 2018 10;10(10):2832-2854

Molecular, Cell and Developmental Biology, University of California Los Angeles, Los Angeles, CA 90095, USA.

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http://dx.doi.org/10.18632/aging.101590DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6224226PMC
October 2018

Genetic Regulation of Fibroblast Activation and Proliferation in Cardiac Fibrosis.

Circulation 2018 09;138(12):1224-1235

Division of Cardiology, Department of Medicine, David Geffen School of Medicine (S.P., S.R., P.Z., M.J.M., J.S.D., A.H.-V., X.W., R.Q., J.M.S., A.J.L., R.A.), University of California, Los Angeles.

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http://dx.doi.org/10.1161/CIRCULATIONAHA.118.035420DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6202226PMC
September 2018

Transcription Factor Zhx2 Deficiency Reduces Atherosclerosis and Promotes Macrophage Apoptosis in Mice.

Arterioscler Thromb Vasc Biol 2018 09;38(9):2016-2027

From the Department of Medicine, David Geffen School of Medicine (A.E., M.M.S., X.W., M.M., Z.Z., H.Q., K.S.D., R.R.S., S.S., A.J.L.).

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http://dx.doi.org/10.1161/ATVBAHA.118.311266DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6202168PMC
September 2018

Genomewide Association Study Identifies Cxcl Family Members as Partial Mediators of LPS-Induced Periodontitis.

J Bone Miner Res 2018 08 22;33(8):1450-1463. Epub 2018 May 22.

Section of Periodontics, University of California, Los Angeles, Los Angeles, CA, USA.

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http://doi.wiley.com/10.1002/jbmr.3440
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http://dx.doi.org/10.1002/jbmr.3440DOI Listing
August 2018

A Strategy for Discovery of Endocrine Interactions with Application to Whole-Body Metabolism.

Cell Metab 2018 May;27(5):1138-1155.e6

Department of Medicine, University of California, Los Angeles, Los Angeles, CA, USA; Department of Human Genetics, University of California, Los Angeles, Los Angeles, CA, USA; Department of Microbiology, Immunology and Molecular Genetics, University of California, Los Angeles, CA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cmet.2018.03.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5935137PMC
May 2018

A personalized, multiomics approach identifies genes involved in cardiac hypertrophy and heart failure.

NPJ Syst Biol Appl 2018 24;4:12. Epub 2018 Feb 24.

1Center for Interdisciplinary Research on Complex Systems, Department of Physics, Northeastern University, Boston, MA USA.

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http://dx.doi.org/10.1038/s41540-018-0046-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5825397PMC
February 2018

A Suite of Tools for Biologists That Improve Accessibility and Visualization of Large Systems Genetics Datasets: Applications to the Hybrid Mouse Diversity Panel.

Methods Mol Biol 2017 ;1488:153-188

Department of Medicine/Division of Cardiology, University of California, Campus - 167917, BH-307 CHS, 10833 Le Conte Ave., Los Angeles, CA, USA.

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http://link.springer.com/10.1007/978-1-4939-6427-7_7
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http://dx.doi.org/10.1007/978-1-4939-6427-7_7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6615944PMC
January 2018

IL-10 Signaling Remodels Adipose Chromatin Architecture to Limit Thermogenesis and Energy Expenditure.

Cell 2018 01 14;172(1-2):218-233.e17. Epub 2017 Dec 14.

Department of Pathology and Laboratory Medicine, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA; Molecular Biology Institute, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA; Howard Hughes Medical Institute, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2017.11.019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5766418PMC
January 2018

Integration of Multi-omics Data from Mouse Diversity Panel Highlights Mitochondrial Dysfunction in Non-alcoholic Fatty Liver Disease.

Cell Syst 2018 Jan 18;6(1):103-115.e7. Epub 2018 Jan 18.

Department of Integrative Biology and Physiology, University of California, Los Angeles, CA, USA; Institute for Quantitative and Computational Biosciences, University of California, Los Angeles, CA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cels.2017.12.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5799036PMC
January 2018

Atherosclerosis: Association between the gut microbiome and atherosclerosis.

Nat Rev Cardiol 2017 Dec 3;14(12):699-700. Epub 2017 Nov 3.

Departments of Microbiology, Medicine, and Human Genetics, University of California Los Angeles, Los Angeles, California 90095-1679, USA.

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http://www.nature.com/doifinder/10.1038/nrcardio.2017.169
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http://dx.doi.org/10.1038/nrcardio.2017.169DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5815826PMC
December 2017

mRNA and plasma hepcidin levels are influenced by sex and strain but do not predict tissue iron levels in inbred mice.

Am J Physiol Gastrointest Liver Physiol 2017 Nov 10;313(5):G511-G523. Epub 2017 Aug 10.

Department of Nutritional Science & Toxicology, University of California, Berkeley, California.

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http://dx.doi.org/10.1152/ajpgi.00307.2016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5792216PMC
November 2017

Functional Characterization of the Coronary Artery Disease Risk Locus.

Circulation 2017 Aug 9;136(5):476-489. Epub 2017 May 9.

From Deutsches Herzzentrum München, Klinik für Herz-und Kreislauferkrankungen, Technische Universität München, Munich, Germany (T.K., J.W., B.W., B.V., S.V.A., T.A.D., H.B.S., P.M.R., A.K., H.S.); Sektion für Funktionelle Genetik am Institut für Humangenetik, Universität zu Lübeck, Germany (J. Eckhold, R.H., F.J.K.); Center for Public Health Genomics, Department of Biomedical Engineering, University of Virginia, Charlottesville (R.A., M.C.); DZHK e.V. (German Center for Cardiovascular Research), Partner Site Munich Heart Alliance, Munich, Germany (A.K., H.S.); Department of Genetics and Genomic Sciences, Icahn Institute for Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, NY (J.L.M.B.); Department of Physiology, Institute of Biomedicine and Translational Medicine, University of Tartu, Estonia (J.L.M.B.); Institut für Integrative und Experimentelle Genomik and Universitäres Herzzentrum Lübeck, Universität zu Lübeck, Germany (J. Erdmann); DZHK e.V. (German Center for Cardiovascular Research), Partner Site Hamburg/Kiel/Lübeck, Lübeck, Germany (J. Erdmann, F.J.K.); and Departments of Human Genetics and Medicine, David Geffen School of Medicine, University of California, Los Angeles (A.J.L., M.C.).

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http://dx.doi.org/10.1161/CIRCULATIONAHA.116.024152DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5560301PMC
August 2017

Natural variation of macrophage activation as disease-relevant phenotype predictive of inflammation and cancer survival.

Nat Commun 2017 07 24;8:16041. Epub 2017 Jul 24.

Division of Inflammation Biology, La Jolla Institute for Allergy and Immunology, La Jolla, California 92037, USA.

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http://dx.doi.org/10.1038/ncomms16041DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5527282PMC
July 2017

A systems genetics approach identifies as a link between cardiomyocyte glucose utilization and hypertrophic response.

Am J Physiol Heart Circ Physiol 2017 Apr 24;312(4):H728-H741. Epub 2017 Feb 24.

Department of Medicine, Cardiology Division at the University of California Los Angeles, Los Angeles, California; and

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http://dx.doi.org/10.1152/ajpheart.00068.2016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5407157PMC
April 2017

The Metabolic Syndrome in Men study: a resource for studies of metabolic and cardiovascular diseases.

J Lipid Res 2017 03 24;58(3):481-493. Epub 2017 Jan 24.

Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI.

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http://dx.doi.org/10.1194/jlr.O072629DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5335588PMC
March 2017

Genetic Regulation of Adipose Gene Expression and Cardio-Metabolic Traits.

Am J Hum Genet 2017 Mar;100(3):428-443

Department of Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA; Department of Human Genetics, University of California, Los Angeles, Los Angeles, CA 90095, USA; Molecular Biology Institute, University of California, Los Angeles, Los Angeles, CA 90095, USA; Department of Microbiology, Immunology and Molecular Genetics, University of California, Los Angeles, Los Angeles, CA 90095, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00029297173002
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http://dx.doi.org/10.1016/j.ajhg.2017.01.027DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5339333PMC
March 2017

Cardiac Fibroblasts Adopt Osteogenic Fates and Can Be Targeted to Attenuate Pathological Heart Calcification.

Cell Stem Cell 2017 02 17;20(2):218-232.e5. Epub 2016 Nov 17.

Division of Cardiology, Department of Medicine, David Geffen School of Medicine, University of California, Los Angeles (UCLA), CA 90095, USA; Cardiovascular Research Laboratory, David Geffen School of Medicine, UCLA, CA 90095, USA; Department of Molecular, Cell and Developmental Biology, School of Letters and Sciences, UCLA, CA 90095, USA; Eli & Edythe Broad Center of Regenerative Medicine and Stem Cell Research, UCLA, CA 90095, USA; Molecular Biology Institute, UCLA, CA 90095, USA; Jonsson Comprehensive Cancer Center, UCLA, CA 90095, USA. Electronic address:

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http://dx.doi.org/10.1016/j.stem.2016.10.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5291784PMC
February 2017

Applications and Limitations of Mouse Models for Understanding Human Atherosclerosis.

Cell Metab 2017 02 1;25(2):248-261. Epub 2016 Dec 1.

Departments of Medicine, Microbiology, and Human Genetics, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cmet.2016.11.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5484632PMC
February 2017

Genetic and hormonal control of hepatic steatosis in female and male mice.

J Lipid Res 2017 01 3;58(1):178-187. Epub 2016 Nov 3.

Department of Medicine, Division of Cardiology, University of California at Los Angeles, Los Angeles, CA

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http://dx.doi.org/10.1194/jlr.M071522DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5234719PMC
January 2017

Systems Genetics Approach Identifies Gene Pathways and Adamts2 as Drivers of Isoproterenol-Induced Cardiac Hypertrophy and Cardiomyopathy in Mice.

Cell Syst 2017 01 17;4(1):121-128.e4. Epub 2016 Nov 17.

Department of Microbiology, Immunology and Molecular Genetics, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA; Department of Medicine, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA; Department of Human Genetics, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cels.2016.10.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5338604PMC
January 2017

Diet, gonadal sex, and sex chromosome complement influence white adipose tissue miRNA expression.

BMC Genomics 2017 01 17;18(1):89. Epub 2017 Jan 17.

Department of Human Genetics, David Geffen School of Medicine, University of California, Los Angeles, CA, USA.

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http://dx.doi.org/10.1186/s12864-017-3484-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5240420PMC
January 2017

Role of lipid phosphate phosphatase 3 in human aortic endothelial cell function.

Cardiovasc Res 2016 12 30;112(3):702-713. Epub 2016 Sep 30.

Sorbonne Universités, UPMC, INSERM UMR_S 1166, ICAN, Genomics and Pathophysiology of Cardiovascular Diseases Team, 91 Bd de l'Hôpital, 75013 Paris, France

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http://dx.doi.org/10.1093/cvr/cvw217DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5157138PMC
December 2016

Efficient and Accurate Multiple-Phenotype Regression Method for High Dimensional Data Considering Population Structure.

Genetics 2016 Dec 21;204(4):1379-1390. Epub 2016 Oct 21.

Bioinformatics Interdepartmental Ph.D. Program, University of California, Los Angeles, California

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http://dx.doi.org/10.1534/genetics.116.189712DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5161272PMC
December 2016

Genome-Wide Association Analysis Identifies Dcc as an Essential Factor in the Innervation of the Peripheral Vestibular System in Inbred Mice.

J Assoc Res Otolaryngol 2016 Oct 18;17(5):417-31. Epub 2016 Aug 18.

USC Tina and Rick Caruso Department of Otolaryngology-Head & Neck Surgery, Zilkha Neurogenetic Institute, Keck Medicine of USC, University of Southern California, Los Angeles, CA, USA.

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http://dx.doi.org/10.1007/s10162-016-0578-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5023540PMC
October 2016

Preservation Analysis of Macrophage Gene Coexpression Between Human and Mouse Identifies PARK2 as a Genetically Controlled Master Regulator of Oxidative Phosphorylation in Humans.

G3 (Bethesda) 2016 10 13;6(10):3361-3371. Epub 2016 Oct 13.

Sorbonne Universités, Université Pierre et Marie Curie, Paris 06, Institut National de la Santé et de la Recherche Médicale, Unité Mixte de Recherche en Santé 1166, F-75013 Paris, France Institute for Cardiometabolism and Nutrition, F-75013 Paris, France

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http://dx.doi.org/10.1534/g3.116.033894DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5068955PMC
October 2016

Elevated Adiponectin Levels Suppress Perivascular and Aortic Inflammation and Prevent AngII-induced Advanced Abdominal Aortic Aneurysms.

Sci Rep 2016 Sep 23;6:31414. Epub 2016 Sep 23.

Division of Endocrinology, Diabetes and Hypertension, David Geffen School of Medicine, University of California, Los Angeles, USA.

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http://dx.doi.org/10.1038/srep31414DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5034224PMC
September 2016

Relationship of disease-associated gene expression to cardiac phenotype is buffered by genetic diversity and chromatin regulation.

Physiol Genomics 2016 08 10;48(8):601-15. Epub 2016 Jun 10.

Department of Anesthesiology, David Geffen School of Medicine at UCLA, Los Angeles, California; Department of Medicine/Cardiology, David Geffen School of Medicine at UCLA, Los Angeles, California; Department of Physiology, David Geffen School of Medicine at UCLA, Los Angeles, California

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http://dx.doi.org/10.1152/physiolgenomics.00035.2016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5005461PMC
August 2016

Imputing Phenotypes for Genome-wide Association Studies.

Am J Hum Genet 2016 Jul 9;99(1):89-103. Epub 2016 Jun 9.

Department of Computer Science, University of California, Los Angeles, Los Angeles, CA 90095, USA; Department of Human Genetics, University of California, Los Angeles, Los Angeles, CA 90095, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00029297163013
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http://dx.doi.org/10.1016/j.ajhg.2016.04.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5005435PMC
July 2016

Sex differences and hormonal effects on gut microbiota composition in mice.

Gut Microbes 2016 07 29;7(4):313-322. Epub 2016 Jun 29.

a Department of Medicine/Division of Cardiology , David Geffen School of Medicine, University of California , Los Angeles , CA , USA.

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http://dx.doi.org/10.1080/19490976.2016.1203502DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4988450PMC
July 2016

Genetic Dissection of Cardiac Remodeling in an Isoproterenol-Induced Heart Failure Mouse Model.

PLoS Genet 2016 07 6;12(7):e1006038. Epub 2016 Jul 6.

Division of Cardiology, Department of Medicine, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, California, United States of America.

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http://dx.doi.org/10.1371/journal.pgen.1006038DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4934852PMC
July 2016

Chromatin variation associated with liver metabolism is mediated by transposable elements.

Epigenetics Chromatin 2016 8;9:28. Epub 2016 Jul 8.

Department of Diabetes Complications and Metabolism, Beckman Research Institute, City of Hope, Duarte, CA USA ; Irell & Manella Graduate School of Biological Sciences, City of Hope, Duarte, CA USA.

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http://dx.doi.org/10.1186/s13072-016-0078-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4939004PMC
July 2016

Tg6F ameliorates the increase in oxidized phospholipids in the jejunum of mice fed unsaturated LysoPC or WD.

J Lipid Res 2016 05 9;57(5):832-47. Epub 2016 Mar 9.

Departments of Medicine, David Geffen School of Medicine at University of California, Los Angeles, Los Angeles, CA 90095-1736.

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http://dx.doi.org/10.1194/jlr.M064352DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4847630PMC
May 2016

Gut Microbial Metabolite TMAO Enhances Platelet Hyperreactivity and Thrombosis Risk.

Cell 2016 Mar 10;165(1):111-124. Epub 2016 Mar 10.

Department of Cellular & Molecular Medicine, Cleveland Clinic, Cleveland, OH 44195, USA; Department of Cardiovascular Medicine, Cleveland Clinic, Cleveland, OH 44195, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2016.02.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4862743PMC
March 2016

Cross-Tissue Regulatory Gene Networks in Coronary Artery Disease.

Cell Syst 2016 03 3;2(3):196-208. Epub 2016 Mar 3.

Cardiovascular Genomics Group, Division of Vascular Biology, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, 171 77 Stockholm, Sweden; Department of Physiology, Institute of Biomedicine and Translation Medicine, University of Tartu, 51014 Tartu, Estonia; Clinical Gene Networks AB, 114 44 Stockholm, Sweden; Department of Genetics & Genomic Sciences, Institute of Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Cardiovascular Institute, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cels.2016.02.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4855300PMC
March 2016