Aldo Pinto

Aldo Pinto

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Aldo Pinto

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Leukotriene-mediated sex dimorphism in murine asthma-like features during allergen sensitization.

Pharmacol Res 2019 01 20;139:182-190. Epub 2018 Nov 20.

Department of Pharmacy, School of Medicine, University of Naples Federico II, Via D. Montesano 49, I-80131 Naples, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.phrs.2018.11.024DOI Listing
January 2019

Polysaccharides based gastroretentive system to sustain piroxicam release: Development and in vivo prolonged anti-inflammatory effect.

Int J Biol Macromol 2018 Dec 29;120(Pt B):2303-2312. Epub 2018 Aug 29.

Department of Pharmacy, University of Salerno, Via Giovanni Paolo II 132, I-84084 Fisciano, (SA), Italy.

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http://dx.doi.org/10.1016/j.ijbiomac.2018.08.140DOI Listing
December 2018

AST-120 Reduces Neuroinflammation Induced by Indoxyl Sulfate in Glial Cells.

J Clin Med 2018 Oct 17;7(10). Epub 2018 Oct 17.

Department of Pharmacy, University of Salerno, Via Giovanni Paolo II 132, Fisciano, I-84084 Salerno, Italy.

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http://www.mdpi.com/2077-0383/7/10/365
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http://dx.doi.org/10.3390/jcm7100365DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6210605PMC
October 2018

Inhibition of Connexin 43 translocation on mitochondria accelerates CoCl-induced apoptotic response in a chemical model of hypoxia.

Toxicol In Vitro 2018 Mar 16;47:120-128. Epub 2017 Nov 16.

Department of Pharmacy, University of Salerno. Via Giovanni Paolo II, Fisciano, Salerno, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.tiv.2017.11.004DOI Listing
March 2018

Diazoxide Improves Mitochondrial Connexin 43 Expression in a Mouse Model of Doxorubicin-Induced Cardiotoxicity.

Int J Mol Sci 2018 Mar 7;19(3). Epub 2018 Mar 7.

Department of Pharmacy, University of Salerno, Via Giovanni Paolo II, 84084 Fisciano, Italy.

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http://dx.doi.org/10.3390/ijms19030757DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5877618PMC
March 2018

Two likely targets for the anti-cancer effect of indole derivatives from cruciferous vegetables: PI3K/Akt/mTOR signalling pathway and the aryl hydrocarbon receptor.

Semin Cancer Biol 2017 10 13;46:132-137. Epub 2017 Jun 13.

Dipartimento di Farmacia, University of Salerno, via Giovanni Paolo II, 84084, Fisciano, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.semcancer.2017.06.002DOI Listing
October 2017

Role of the inflammasome in chronic obstructive pulmonary disease (COPD).

Oncotarget 2017 Oct 13;8(47):81813-81824. Epub 2017 May 13.

Department of Pharmacy, University of Salerno, ImmunePharma s.r.l., Fisciano, Salerno, Italy.

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http://dx.doi.org/10.18632/oncotarget.17850DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5669850PMC
October 2017

IL-1α and IL-1β-producing macrophages populate lung tumor lesions in mice.

Oncotarget 2016 Sep;7(36):58181-58192

Department of Pharmacy (DIFARMA), University of Salerno, Salerno, Fisciano, 84084, Italy.

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http://dx.doi.org/10.18632/oncotarget.11276DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5295423PMC
September 2016

Myeloid cells in the tumor microenvironment: Role of adenosine.

Oncoimmunology 2016 Mar 3;5(3):e1108515. Epub 2015 Dec 3.

Division of Pharmacology and Chemotherapy, Department of Clinical and Experimental Medicine, University of Pisa , Pisa, Italy.

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http://dx.doi.org/10.1080/2162402X.2015.1108515DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4839347PMC
March 2016

Inflammatory mediators in a short-time mouse model of doxorubicin-induced cardiotoxicity.

Toxicol Appl Pharmacol 2016 Feb 11;293:44-52. Epub 2016 Jan 11.

Department of Pharmacy, University of Salerno, Fisciano, SA, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.taap.2016.01.006DOI Listing
February 2016

Role of connexin 43 in cardiovascular diseases.

Eur J Pharmacol 2015 Dec 20;768:71-6. Epub 2015 Oct 20.

Department of Pharmacy, University of Salerno, Italy. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00142999153031
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http://dx.doi.org/10.1016/j.ejphar.2015.10.030DOI Listing
December 2015

Doxorubicin-Mediated Cardiotoxicity: Role of Mitochondrial Connexin 43.

Cardiovasc Toxicol 2015 Oct;15(4):366-76

Department of Pharmacy, School of Pharmacy, University of Salerno, Via Giovanni Paolo II 132, 84084, Fisciano, SA, Italy.

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http://dx.doi.org/10.1007/s12012-014-9305-8DOI Listing
October 2015

Design and In Vivo Anti-Inflammatory Effect of Ketoprofen Delayed Delivery Systems.

J Pharm Sci 2015 Oct 18;104(10):3451-8. Epub 2015 Jun 18.

Department of Pharmacy, University of Salerno, I-84084, Fisciano, (SA), Italy.

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http://dx.doi.org/10.1002/jps.24554DOI Listing
October 2015

Pharmacological inhibition of caspase-8 limits lung tumour outgrowth.

Br J Pharmacol 2015 Aug 12;172(15):3917-28. Epub 2015 Jun 12.

Department of Pharmacy, University of Salerno, Fisciano, Italy.

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http://dx.doi.org/10.1111/bph.13176DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4523345PMC
August 2015

A single infection with Chlamydia pneumoniae is sufficient to exacerbate atherosclerosis in ApoE deficient mice.

Cell Immunol 2015 Mar 30;294(1):25-32. Epub 2015 Jan 30.

Division of Pediatric Infectious Diseases and Immunology, Cedars Sinai Medical Center and David Geffen School of Medicine, University of California, Los Angeles, CA 90048, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cellimm.2015.01.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4391498PMC
March 2015

L-Arginine and its metabolites in kidney and cardiovascular disease.

Amino Acids 2014 Oct 27;46(10):2271-86. Epub 2014 Aug 27.

Department of Pharmacy, University of Salerno, Via Giovanni Paolo II 132, 84084, Fisciano, SA, Italy.

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http://dx.doi.org/10.1007/s00726-014-1825-9DOI Listing
October 2014

Inflammasome: cancer's friend or foe?

Pharmacol Ther 2014 Jul 8;143(1):24-33. Epub 2014 Feb 8.

Department of Pharmacy (DIFARMA), University of Salerno, Fisciano 84084, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.pharmthera.2014.02.002DOI Listing
July 2014

Plasmacytoid dendritic cells contribute to doxorubicin-induced tumor arrest in a mouse model of pulmonary metastasis.

J Immunother 2014 May;37(4):214-24

Department of Pharmacy (DIFARMA), University of Salerno, Fisciano, Salerno, Italy.

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http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:land
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http://dx.doi.org/10.1097/CJI.0000000000000026DOI Listing
May 2014

Adenosine limits the therapeutic effectiveness of anti-CTLA4 mAb in a mouse melanoma model.

Am J Cancer Res 2014 1;4(2):172-81. Epub 2014 Mar 1.

Department of Pharmacy, University of Salerno Italy.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3960454PMC
March 2014

Adenosine receptors as potential targets in melanoma.

Pharmacol Res 2013 Oct 13;76:34-40. Epub 2013 Jul 13.

Centre for Cell Death, Cancer, and Inflammation (CCCI), UCL Cancer Institute, University College London, London, UK.

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http://dx.doi.org/10.1016/j.phrs.2013.07.002DOI Listing
October 2013

Antiadrenergic effect of adenosine involves connexin 43 turn-over in H9c2 cells.

Eur J Pharmacol 2013 Sep 5;715(1-3):56-61. Epub 2013 Jul 5.

Department of Pharmacy, University of Salerno, Fisciano, Salerno 84084, Italy.

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http://dx.doi.org/10.1016/j.ejphar.2013.06.019DOI Listing
September 2013

New insights on cytotoxic activity of group 3 and lanthanide compounds: complexes with [N,N,N]-scorpionate ligands.

J Pharm Pharmacol 2013 Sep 30;65(9):1354-9. Epub 2013 Jul 30.

Dipartimento di Scienze Farmaceutiche, Università di Salerno, Fisciano, Italy.

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http://doi.wiley.com/10.1111/jphp.12112
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http://dx.doi.org/10.1111/jphp.12112DOI Listing
September 2013

Plasmacytoid dendritic cells play a key role in tumor progression in lipopolysaccharide-stimulated lung tumor-bearing mice.

J Immunol 2013 Mar 25;190(5):2391-402. Epub 2013 Jan 25.

Department of Pharmaceutical and Biomedical Sciences, University of Salerno, Fisciano 84084, Italy.

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http://www.jimmunol.org/cgi/doi/10.4049/jimmunol.1202086
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http://dx.doi.org/10.4049/jimmunol.1202086DOI Listing
March 2013

A fuzzy model to interpret data of drive performances from patients with sleep deprivation.

Comput Math Methods Med 2012 30;2012:868410. Epub 2012 Aug 30.

Department of Pharmaceutical and Biomedical Sciences, University of Salerno, Via Ponte Don Melillo, 84084 Fisciano, Italy.

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http://dx.doi.org/10.1155/2012/868410DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3437303PMC
January 2013

The adenosinergic system in cancer: Key therapeutic target.

Oncoimmunology 2013 Jan;2(1):e22448

Department of Pharmaceutical and Biomedical Sciences; University of Salerno; Salerno, Italy.

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http://dx.doi.org/10.4161/onci.22448DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3583919PMC
January 2013

Inhibition of CD73 improves B cell-mediated anti-tumor immunity in a mouse model of melanoma.

J Immunol 2012 Sep 23;189(5):2226-33. Epub 2012 Jul 23.

Department of Pharmaceutical and Biomedical Sciences, University of Salerno, Fisciano, 84084 Salerno, Italy.

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http://dx.doi.org/10.4049/jimmunol.1200744DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3442235PMC
September 2012

Plasmacytoid dendritic cells and their therapeutic activity in cancer.

Oncoimmunology 2012 Aug;1(5):726-734

Pharmaceutical and Biomedical Sciences Department (FARMABIOMED); University of Salerno; Fisciano, Italy.

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http://dx.doi.org/10.4161/onci.20171DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3429576PMC
August 2012

Polyinosinic-polycytidylic acid limits tumor outgrowth in a mouse model of metastatic lung cancer.

J Immunol 2012 Jun 18;188(11):5357-64. Epub 2012 Apr 18.

Department of Pharmaceutical and Biomedical Science, University of Salerno, Fisciano, Salerno 84084, Italy.

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http://dx.doi.org/10.4049/jimmunol.1103811DOI Listing
June 2012

Lung cancer and Toll-like receptors.

Cancer Immunol Immunother 2011 Sep 26;60(9):1211-20. Epub 2011 Jul 26.

Pharmaceutical and Biomedical Sciences Department, University of Salerno, 84084 Fisciano, Salerno, Italy.

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http://dx.doi.org/10.1007/s00262-011-1057-8DOI Listing
September 2011

Plasmacytoid dendritic cells: from heart to vessels.

Int J Vasc Med 2010 22;2010:430318. Epub 2010 Sep 22.

Pharmaceutical Science Department, University of Salerno, 84084 Fisciano, Italy.

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http://www.hindawi.com/journals/ijvm/aip/430318.pdf
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http://www.hindawi.com/journals/ijvm/2010/430318/
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http://dx.doi.org/10.1155/2010/430318DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2989744PMC
July 2011

CpG-ODN increases the release of VEGF in a mouse model of lung carcinoma.

Int J Cancer 2011 Jun 8;128(12):2815-22. Epub 2010 Oct 8.

Department of Pharmaceutical Science, University of Salerno, Fisciano, Italy.

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http://dx.doi.org/10.1002/ijc.25626DOI Listing
June 2011

Cl-IB-MECA enhances TNF-α release in peritoneal macrophages stimulated with LPS.

Cytokine 2011 May 26;54(2):161-6. Epub 2011 Feb 26.

Department of Pharmaceutical Sciences, University of Salerno, Fisciano Salerno, Italy.

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http://dx.doi.org/10.1016/j.cyto.2011.02.002DOI Listing
May 2011

Hydrogen sulfide-induced dual vascular effect involves arachidonic acid cascade in rat mesenteric arterial bed.

J Pharmacol Exp Ther 2011 Apr 12;337(1):59-64. Epub 2011 Jan 12.

Department of Experimental Pharmacology, University of Naples Federico II, Italy.

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http://dx.doi.org/10.1124/jpet.110.176016DOI Listing
April 2011

NK1.1 cells and CD8 T cells mediate the antitumor activity of Cl-IB-MECA in a mouse melanoma model.

Neoplasia 2011 Apr;13(4):365-73

Department of Pharmaceutical Sciences, Biomedical Section, University of Salerno, Fisciano (SA), Italy.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3071085PMC
April 2011

Synthesis, characterization and cytotoxicity studies of methoxy alkyl substituted metallocenes.

Eur J Med Chem 2011 Jan 27;46(1):122-8. Epub 2010 Oct 27.

Dipartimento di Chimica, Università di Salerno, Via Ponte don Melillo, 84084 Fisciano (SA), Italy.

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http://dx.doi.org/10.1016/j.ejmech.2010.10.021DOI Listing
January 2011

Cytotoxic activity of nemorosone in human MCF-7 breast cancer cells.

Can J Physiol Pharmacol 2011 Jan;89(1):50-7

Department of Pharmaceutical Sciences, University of Salerno, Fisciano, Italy.

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http://dx.doi.org/10.1139/y10-100DOI Listing
January 2011

Pro-apoptotic effect of methylguanidine on hydrogen peroxide-treated rat glioma cell line.

Neurochem Int 2010 Nov 3;57(5):518-24. Epub 2010 Jul 3.

Department of Pharmaceutical Sciences, School of Pharmacy, University of Salerno, Fisciano (SA), Italy.

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http://dx.doi.org/10.1016/j.neuint.2010.06.016DOI Listing
November 2010

Synthesis and cytotoxic activities of group 3 metal complexes having monoanionic tridentate ligands.

Eur J Med Chem 2010 Sep 12;45(9):4169-74. Epub 2010 Jun 12.

Dipartimento di Scienze Farmaceutiche, Università di Salerno, Via Ponte don Melillo, 84084 Fisciano (SA), Italy.

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http://linkinghub.elsevier.com/retrieve/pii/S022352341000452
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http://dx.doi.org/10.1016/j.ejmech.2010.06.008DOI Listing
September 2010

Role of plasmacytoid dendritic cells in lung-associated inflammation.

Recent Pat Inflamm Allergy Drug Discov 2010 Jun;4(2):138-43

Pharmaceutical Sciences Department, University of Salerno, Salerno, Italy.

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June 2010

The activation of liver X receptors inhibits toll-like receptor-9-induced foam cell formation.

J Cell Physiol 2010 Apr;223(1):158-67

Pharmaceutical Science Department, University of Salerno, 84084 Fisciano, Salerno, Italy.

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http://dx.doi.org/10.1002/jcp.22022DOI Listing
April 2010

Antiproliferative activity of brown Cuban propolis extract on human breast cancer cells.

Nat Prod Commun 2009 Dec;4(12):1711-6

Department of Pharmaceutical Sciences, Via Ponte Don Melillo 84135, Fisciano, Salerno, Italy.

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December 2009

Cl-IB-MECA enhances TRAIL-induced apoptosis via the modulation of NF-kappaB signalling pathway in thyroid cancer cells.

J Cell Physiol 2009 Nov;221(2):378-86

Pharmaceutical Sciences Department, University of Salerno, Fisciano, Salerno, Italy.

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http://doi.wiley.com/10.1002/jcp.21863
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http://dx.doi.org/10.1002/jcp.21863DOI Listing
November 2009

Antioxidant activity of diphenylpropionamide derivatives: synthesis, biological evaluation and computational analysis.

Molecules 2008 Mar 28;13(4):749-61. Epub 2008 Mar 28.

Department of Pharmaceutical Sciences, University of Salerno,Via Ponte don Melillo, 84084 Fisciano, (SA) Italy.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6244830PMC
March 2008

Cl-IB-MECA inhibits human thyroid cancer cell proliferation independently of A3 adenosine receptor activation.

Cancer Biol Ther 2008 Feb 14;7(2):278-84. Epub 2007 Nov 14.

Department of Pharmaceutical Science, Biomedical Section, University of Salerno, Salerno, Italy.

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February 2008

Tyrphostin AG 126 reduces intestinal ischemia-reperfusion injury in the rat.

Naunyn Schmiedebergs Arch Pharmacol 2006 Feb 17;372(5):362-73. Epub 2006 Feb 17.

Department of Pharmaceutical Sciences, University of Salerno, Via Ponte Don Melillo 11/c, 84084 Fisciano-Salerno, Italy.

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http://dx.doi.org/10.1007/s00210-005-0029-yDOI Listing
February 2006

(-)-Linalool inhibits in vitro NO formation: Probable involvement in the antinociceptive activity of this monoterpene compound.

Life Sci 2006 Jan 31;78(7):719-23. Epub 2005 Aug 31.

Dipartimento di Scienze del Farmaco, Università degli Studi di Sassari, via Muroni 23/a, 07100 Sassari, Italy.

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http://dx.doi.org/10.1016/j.lfs.2005.05.065DOI Listing
January 2006

The cyclopentenone prostaglandin 15-deoxydelta(12,14)-prostaglandin J2 attenuates the development of zymosan-induced shock.

Intensive Care Med 2005 May 15;31(5):693-700. Epub 2005 Mar 15.

Department of Pharmaceutical Sciences, University of Salerno, Fisciano-Salerno, Italy.

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http://dx.doi.org/10.1007/s00134-005-2596-2DOI Listing
May 2005

Effect of methylguanidine in a model of septic shock induced by LPS.

Free Radic Res 2004 Nov;38(11):1143-53

Department of Pharmaceutical Sciences, University of Salerno, Via Ponte Don Melillo 11/c, 84084 Fisciano-Salerno, Italy.

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http://dx.doi.org/10.1080/10715760410001725517DOI Listing
November 2004

Methylguanidine reduces the development of non septic shock induced by zymosan in mice.

Life Sci 2004 Aug;75(12):1417-33

Department of Pharmaceutical Sciences, University of Salerno, Via Ponte Don Melillo 11/c, 84084, Fisciano--Salerno, Italy.

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http://dx.doi.org/10.1016/j.lfs.2004.02.031DOI Listing
August 2004

Inhibition of inducible nitric oxide synthase expression by yuccaol C from Yucca schidigera roezl.

Life Sci 2004 Aug;75(12):1491-501

Department of Pharmaceutical Sciences, University of Salerno, via Ponte Don Melillo-84084, Fisciano, Salerno, Italy.

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http://dx.doi.org/10.1016/j.lfs.2004.03.013DOI Listing
August 2004

Melatonin prevents lipopolysaccharide-induced hyporeactivity in rat.

J Pineal Res 2004 Apr;36(3):146-54

Dipartimento di Farmacologia Sperimentale, Università degli Studi di Napoli 'Federico II', Via D. Montesano, Napoli, Italy.

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April 2004

Inhibitory effect of ginger (Zingiber officinale) on rat ileal motility in vitro.

Life Sci 2004 Apr;74(23):2889-96

Department of Experimental Pharmacology, University of Naples Federico II, Via D. Montesano 49, 80131 Naples, Italy.

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http://linkinghub.elsevier.com/retrieve/pii/S002432050400115
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http://dx.doi.org/10.1016/j.lfs.2003.10.023DOI Listing
April 2004

Calpain inhibitor I reduces intestinal ischemia-reperfusion injury in the rat.

Shock 2004 Jan;21(1):38-44

Department of Pharmaceutical Sciences, University of Salerno, Fisciano-Salerno, Italy.

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http://dx.doi.org/10.1097/01.shk.0000095056.62263.b2DOI Listing
January 2004

Effect of methylguanidine in carrageenan-induced acute inflammation in the rats.

Eur J Pharmacol 2004 Jan;484(2-3):341-50

Department of Pharmaceutical Sciences University of Salerno, Via Ponte Don Melillo 11/c, 84084 Fisciano-Salerno, Italy.

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January 2004

Cytotoxic saponins from Schefflera fagueti.

Planta Med 2003 Aug;69(8):750-6

Dipartimento di Scienze Farmaceutiche, Università di Salerno, Fisciano, Salerno, Italy.

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http://dx.doi.org/10.1055/s-2003-42780DOI Listing
August 2003

A superoxide dismutase mimetic with catalase activity (EUK-8) reduces the organ injury in endotoxic shock.

Eur J Pharmacol 2003 Apr;466(1-2):181-9

The William Harvey Research Institute, St. Bartholomew's and The Royal London School of Medicine and Dentistry, Charterhouse Square, EC1M 6BQ, London, UK.

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April 2003

Effect of piperine, the active ingredient of black pepper, on intestinal secretion in mice.

Life Sci 2002 Sep;71(19):2311-7

Department of Pharmaceutical Science, University of Salerno, Italy.

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September 2002

Synthesis and vasorelaxant activity of new 1,4-benzoxazine derivatives potassium channel openers.

Bioorg Med Chem 2002 Aug;10(8):2663-9

Dipartimento di Chimica Farmaceutica e Tossicologica, Università di Napoli Federico II, Via D. Montesano 49, 80131 Naples, Italy.

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August 2002

Beneficial effects of caffeic acid phenethyl ester in a rat model of vascular injury.

Br J Pharmacol 2002 Jun;136(3):353-60

Department of Pharmaceutical Science, University of Salerno, via Ponte Don Melillo Fisciano, Salerno, Italy.

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http://dx.doi.org/10.1038/sj.bjp.0704720DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1573358PMC
June 2002

17-beta-oestradiol-induced vasorelaxation in vitro is mediated by eNOS through hsp90 and akt/pkb dependent mechanism.

Br J Pharmacol 2002 Apr;135(7):1695-700

Department of Pharmaceutical Science, Faculty of Pharmacy, University of Salerno, Fisciano (SA) Italy.

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http://dx.doi.org/10.1038/sj.bjp.0704641DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1573306PMC
April 2002

Relaxant effect of capsazepine in the isolated rat ileum.

Naunyn Schmiedebergs Arch Pharmacol 2002 Mar 1;365(3):187-92. Epub 2002 Feb 1.

Department of Experimental Pharmacology, University of Naples "Federico II", via D. Montesano 49, 80131 Naples, Italy.

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http://link.springer.com/content/pdf/10.1007/s00210-001-0522
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http://link.springer.com/10.1007/s00210-001-0522-x
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http://dx.doi.org/10.1007/s00210-001-0522-xDOI Listing
March 2002

Superoxide dismutase mimetic with catalase activity, EUK-134, attenuates the multiple organ injury and dysfunction caused by endotoxin in the rat.

Med Sci Monit 2002 Jan;8(1):BR1-7

The William Harvey Research Institute, St. Bartholomew's and The Royal London School of Medicine and Dentistry, London, UK.

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January 2002