Publications by authors named "Alberto Serrano-Pozo"

42Publications

Systematic review and meta-analysis of human transcriptomics reveals neuroinflammation, deficient energy metabolism, and proteostasis failure across neurodegeneration.

Neurobiol Dis 2020 Dec 19;149:105225. Epub 2020 Dec 19.

Department of Neurology, Massachusetts General Hospital, Boston, MA 02114, United States of America; MIND Data Science Lab, Cambridge, MA 02139, United States of America; MassGeneral Institute for Neurodegenerative Disease, Charlestown, MA 02129, United States of America; Harvard Medical School, Boston, MA 02115, United States of America. Electronic address:

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December 2020

APOE and Alzheimer's disease: advances in genetics, pathophysiology, and therapeutic approaches.

Lancet Neurol 2021 01;20(1):68-80

Department of Neurology, Massachusetts General Hospital, Boston, MA, USA; Massachusetts Alzheimer's Disease Research Center, Charlestown, MA, USA; Harvard Medical School, Boston, MA, USA. Electronic address:

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January 2021

Meta-analysis of mouse transcriptomic studies supports a context-dependent astrocyte reaction in acute CNS injury versus neurodegeneration.

J Neuroinflammation 2020 Jul 31;17(1):227. Epub 2020 Jul 31.

Department of Neurology, Massachusetts General Hospital, Boston, MA, 02114, USA.

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July 2020

Characterization of the 18 kDa translocator protein (TSPO) expression in post-mortem normal and Alzheimer's disease brains.

Brain Pathol 2020 01 25;30(1):151-164. Epub 2019 Jul 25.

Department of Neurology, Massachusetts General Hospital, Boston, MA.

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January 2020

Is Alzheimer's Disease Risk Modifiable?

J Alzheimers Dis 2019 ;67(3):795-819

Department of Neurology, Massachusetts General Hospital, Boston, MA, USA.

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May 2020

Editorial: The Role of Glia in Alzheimer's Disease.

Front Neurol 2018 11;9:1161. Epub 2019 Jan 11.

Department of Neurology of the Massachusetts General Hospital, Harvard Medical School, Boston, MA, United States.

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January 2019

Deciphering the Astrocyte Reaction in Alzheimer's Disease.

Front Aging Neurosci 2018 25;10:114. Epub 2018 Apr 25.

Alzheimer's Research Unit, MassGeneral Institute for Neurodegenerative Diseases (MIND), Department of Neurology, Massachusetts General Hospital, Boston, MA, United States.

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April 2018

Four Decades of Research in Alzheimer's Disease (1975-2014): A Bibliometric and Scientometric Analysis.

J Alzheimers Dis 2017 ;59(2):763-783

Department of Neurology, University of IowaHospitals and Clinics, Iowa City, IA, USA.

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April 2018

Acute and Chronic Sustained Hypoxia Do Not Substantially Regulate Amyloid-β Peptide Generation In Vivo.

PLoS One 2017 18;12(1):e0170345. Epub 2017 Jan 18.

Instituto de Biomedicina de Sevilla (IBiS), Hospital Universitario Virgen del Rocío/CSIC/Universidad de Sevilla, Seville, Spain.

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August 2017

Thal Amyloid Stages Do Not Significantly Impact the Correlation Between Neuropathological Change and Cognition in the Alzheimer Disease Continuum.

J Neuropathol Exp Neurol 2016 06 22;75(6):516-26. Epub 2016 Apr 22.

From the Department of Neurology of the University of Iowa Hospitals & Clinics, Iowa City, Iowa (AS-P); Department of Biostatistics and Epidemiology of the University of Massachusetts, Amherst, Massachusetts (JQ); Massachusetts General Hospital Biostatistics Center, Boston, Massachusetts (AM); Department of Biostatistics, University of Washington, Seattle, Washington (SEM); Department of Pathology, School of Medicine of the University of Washington, Seattle, Washington (TJM); C. S. Kubik Laboratory for Neuropathology of the Massachusetts General Hospital (MPF), Department of Neurology of the Massachusetts General Hospital, Boston, Massachusetts (BTH); Department of Biostatistics of the Harvard T. H. Chan School of Public Health, Boston, Massachusetts (RAB); and Massachusetts Alzheimer Disease Research Center, Charlestown, Massachusetts (MPF, RAB, BTH).

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June 2016

Plaque-Associated Local Toxicity Increases over the Clinical Course of Alzheimer Disease.

Am J Pathol 2016 Feb 11;186(2):375-84. Epub 2015 Dec 11.

Massachusetts Alzheimer Disease Research Center, Massachusetts General Hospital, Charlestown, Massachusetts; Department of Neurology, Massachusetts General Hospital, Boston, Massachusetts. Electronic address:

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February 2016

Alzheimer disease: Alzheimer dementia with sparse amyloid-AD mimic or variant?

Nat Rev Neurol 2015 Dec 10;11(12):674-5. Epub 2015 Nov 10.

Massachusetts Alzheimer Disease Research Center, 16th Street, Building 114, Charlestown, MA 02129, USA.

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December 2015

Inhibition of amyloid-β plaque formation by α-synuclein.

Nat Med 2015 Jul 22;21(7):802-7. Epub 2015 Jun 22.

1] Adolf Butenandt Institute, Department of Biochemistry, Ludwig-Maximilians University, Munich, Germany. [2] Neurocenter, Department of Neurology, University of Freiburg, Freiburg, Germany.

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July 2015

APOEε2 is associated with milder clinical and pathological Alzheimer disease.

Ann Neurol 2015 Jun;77(6):917-29

Department of Neurology, Massachusetts General Hospital, Boston, MA.

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June 2015

Frequent and symmetric deposition of misfolded tau oligomers within presynaptic and postsynaptic terminals in Alzheimer's disease.

Acta Neuropathol Commun 2014 Oct 21;2:146. Epub 2014 Oct 21.

MassGeneral Institute for Neurodegenerative Disease, Massachusetts General Hospital, Harvard Medical School, Building 114, 16th Street, Charlestown, MA, 02129, USA.

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October 2014

Mild to moderate Alzheimer dementia with insufficient neuropathological changes.

Ann Neurol 2014 Apr 8;75(4):597-601. Epub 2014 Apr 8.

Massachusetts Alzheimer Disease Research Center, Charlestown, MA; Department of Neurology, Massachusetts General Hospital, Boston, MA; Department of Neurology, University of Iowa Hospitals & Clinics, Iowa city, IA.

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April 2014