Publications by authors named "Alberto L Horenstein"

37Publications

The Circular Life of Human CD38: From Basic Science to Clinics and Back.

Molecules 2020 Oct 21;25(20). Epub 2020 Oct 21.

Dipartimento Scienze Mediche, Università di Torino, Centro Ricerche Medicina Sperimentale (CeRMS) and Fondazione Ricerca Molinette Onlus, 10121 Torino, Italy.

View Article and Find Full Text PDF
October 2020

Microvesicles expressing adenosinergic ectoenzymes and their potential role in modulating bone marrow infiltration by neuroblastoma cells.

Oncoimmunology 2019;8(5):e1574198. Epub 2019 Feb 19.

Department of Medical Sciences, Laboratory of Immunogenetics, University of Torino, Torino, Italy.

View Article and Find Full Text PDF
February 2019

CD38: A Target for Immunotherapeutic Approaches in Multiple Myeloma.

Front Immunol 2018 28;9:2722. Epub 2018 Nov 28.

Laboratory of Immunogenetics, Department of Medical Sciences, University of Torino, Torino, Italy.

View Article and Find Full Text PDF
October 2019

Cytokine-Induced Killer Cells Express CD39, CD38, CD203a, CD73 Ectoenzymes and P1 Adenosinergic Receptors.

Front Pharmacol 2018 20;9:196. Epub 2018 Apr 20.

Department of Life Science and Biotechnology, Section of Microbiology and Applied Pathology, University of Ferrara, Ferrara, Italy.

View Article and Find Full Text PDF
April 2018

Roles and Modalities of Ectonucleotidases in Remodeling the Multiple Myeloma Niche.

Front Immunol 2017 20;8:305. Epub 2017 Mar 20.

Laboratory of Immunogenetics and CeRMS, Department of Medical Sciences, University of Torino , Torino , Italy.

View Article and Find Full Text PDF
March 2017

Antibody mimicry, receptors and clinical applications.

Hum Antibodies 2017 ;25(3-4):75-85

Laboratory of Immunogenetics, Department of Medical Sciences, University of Torino, Torino 10126, Italy.

View Article and Find Full Text PDF
February 2018

Adenosine Generated in the Bone Marrow Niche Through a CD38-Mediated Pathway Correlates with Progression of Human Myeloma.

Mol Med 2016 Dec 13;22:694-704. Epub 2016 Oct 13.

Laboratory of Immunogenetics, Department of Medical Sciences, University of Torino, Torino 10126, Italy.

View Article and Find Full Text PDF
December 2016

A non-canonical adenosinergic pathway led by CD38 in human melanoma cells induces suppression of T cell proliferation.

Oncotarget 2015 Sep;6(28):25602-18

Department of Medical Sciences, Laboratory of Immunogenetics and CeRMS, University of Torino, and Transplant Immunology, Città della Salute e della Scienza, Torino, Italy.

View Article and Find Full Text PDF
September 2015

CD56brightCD16- NK Cells Produce Adenosine through a CD38-Mediated Pathway and Act as Regulatory Cells Inhibiting Autologous CD4+ T Cell Proliferation.

J Immunol 2015 Aug 19;195(3):965-72. Epub 2015 Jun 19.

Laboratory of Immunogenetics and CeRMS, Department of Medical Sciences, University of Turin, Turin 10126, Italy; Immunologia dei Trapianti, Città della Salute e della Scienza, Turin 10126, Italy;

View Article and Find Full Text PDF
August 2015

Unconventional, adenosine-producing suppressor T cells induced by dendritic cells exposed to BPZE1 pertussis vaccine.

J Leukoc Biol 2015 Oct 18;98(4):631-9. Epub 2015 Jun 18.

*Anti-Infectious Immunity Unit, Department of Infectious Parasitic and Immune-Mediated Diseases, Istituto Superiore di Sanità, Rome, Italy; INSERM U1019, Lille, France; CNRS UMR8204, Lille, France; Institut Pasteur de Lille, Center for Infection and Immunity, Lille, France; University of Lille Nord de France, Lille, France; Laboratory of Immunogenetics, Department of Medical Sciences and CERMS, University of Torino, Torino, Italy; **Transplantation Immunology Service, Città della Salute e della Scienza Hospital, Torino, Italy.

View Article and Find Full Text PDF
October 2015

The ADP-ribosyl cyclases--the current evolutionary state of the ARCs.

Front Biosci (Landmark Ed) 2014 Jun 1;19:986-1002. Epub 2014 Jun 1.

Immunogenetics Lab, Department of Medical Sciences, University of Torino, Via Santena 19, 10126 Torino, Italy.

View Article and Find Full Text PDF
June 2014

CD38 ligation in peripheral blood mononuclear cells of myeloma patients induces release of protumorigenic IL-6 and impaired secretion of IFNγ cytokines and proliferation.

Mediators Inflamm 2013 30;2013:564687. Epub 2013 Dec 30.

Department of Infectious, Parasitic and Immune-mediated Diseases, Anti-infectious Immunity Unit, Istituto Superiore di Sanità, 00161 Rome, Italy.

View Article and Find Full Text PDF
June 2014

CD38 and bone marrow microenvironment.

Front Biosci (Landmark Ed) 2014 Jan 1;19:152-62. Epub 2014 Jan 1.

Laboratory of Immunogenetics, Department of Medical Sciences, University of Torino Medical School, Via Santena 19, 10126 Torino, Italy.

View Article and Find Full Text PDF
January 2014

A CD38/CD203a/CD73 ectoenzymatic pathway independent of CD39 drives a novel adenosinergic loop in human T lymphocytes.

Oncoimmunology 2013 Sep 26;2(9):e26246. Epub 2013 Sep 26.

Laboratory of Immunogenetics; Department of Medical Sciences; University of Torino; Torino, Italy ; Research Center for Experimental Medicine; University of Torino; Torino, Italy ; Transplantation Immunology; "Città della Salute e della Scienza" Hospital; Torino, Italy.

View Article and Find Full Text PDF
September 2013

Anti-CD38 antibody therapy: windows of opportunity yielded by the functional characteristics of the target molecule.

Mol Med 2013 May 20;19:99-108. Epub 2013 May 20.

Laboratory of Immunogenetics, Department of Medical Sciences, University of Torino Medical School, Torino, Italy.

View Article and Find Full Text PDF
May 2013

CD38 and CD157: a long journey from activation markers to multifunctional molecules.

Cytometry B Clin Cytom 2013 Jul-Aug;84(4):207-17. Epub 2013 Apr 10.

Department of Medical Sciences, Laboratory of Immunogenetics, University of Torino Medical School, Torino, Italy.

View Article and Find Full Text PDF
February 2014

The CD157-integrin partnership controls transendothelial migration and adhesion of human monocytes.

J Biol Chem 2011 May 8;286(21):18681-91. Epub 2011 Apr 8.

Laboratory of Immunogenetics, Department of Genetics, University of Torino Medical School, 10126 Torino, Italy.

View Article and Find Full Text PDF
May 2011

The hidden life of NAD+-consuming ectoenzymes in the endocrine system.

J Mol Endocrinol 2010 Oct 21;45(4):183-91. Epub 2010 Jul 21.

Laboratory of Immunogenetics and CeRMS, Department of Genetics, Biology and Biochemistry, University of Torino School of Medicine, Turin, Italy.

View Article and Find Full Text PDF
October 2010

CD38 and CD157 ectoenzymes mark cell subsets in the human corneal limbus.

Mol Med 2009 Mar-Apr;15(3-4):76-84. Epub 2008 Nov 19.

Department of Genetics, Biology and Biochemistry, University of Torino Medical School, Torino, Italy.

View Article and Find Full Text PDF
April 2009

Evolution and function of the ADP ribosyl cyclase/CD38 gene family in physiology and pathology.

Physiol Rev 2008 Jul;88(3):841-86

Laboratory of Immunogenetics, Department of Genetics, Biology, and Biochemistry and Centro di Ricerca in Medicina Sperimentale, University of Torino Medical School, Torino, Italy.

View Article and Find Full Text PDF
July 2008

Purification of clinical-grade monoclonal antibodies by chromatographic methods.

Methods Mol Biol 2005 ;308:191-208

Laboratory of Immunogenetics, Department of Genetics, Biology and Biochemistry, University of Torino Medical School and Research Center for Experimental Medicine (CeRMS), San Giovanni Battista Hospital, Turin, Italy.

View Article and Find Full Text PDF
September 2005

CD38 and CD100 lead a network of surface receptors relaying positive signals for B-CLL growth and survival.

Blood 2005 Apr 21;105(8):3042-50. Epub 2004 Dec 21.

Department of Genetics, Biology and Biochemistry, University of Torino Medical School, Torino, Italy.

View Article and Find Full Text PDF
April 2005

Functional, structural, and distribution analysis of the chorionic gonadotropin receptor using murine monoclonal antibodies.

J Clin Endocrinol Metab 2003 Nov;88(11):5537-46

Department of Genetics, Biology and Biochemistry and Research Center for Experimental Medicine, University of Torino, Torino 10126, Italy.

View Article and Find Full Text PDF
November 2003

Design and scaleup of downstream processing of monoclonal antibodies for cancer therapy: from research to clinical proof of principle.

J Immunol Methods 2003 Apr;275(1-2):99-112

Laboratory of Immunogenetics, Department of Genetics, Biology and Biochemistry, University of Torino Medical School, Turin, Italy.

View Article and Find Full Text PDF
April 2003