Publications by authors named "Alberto J Espay"

100Publications

Rivastigmine in Parkinson's Disease Dementia with Orthostatic Hypotension.

Ann Neurol 2020 Oct 5. Epub 2020 Oct 5.

Neuroscience Translational Medicine, Novartis Institutes for Biomedical Research, Neurology, and Neurosurgery, McGill University, Montreal, Quebec, Canada.

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http://dx.doi.org/10.1002/ana.25923DOI Listing
October 2020

Gaps, Controversies, and Proposed Roadmap for Research in Normal Pressure Hydrocephalus.

Mov Disord 2020 Sep 22. Epub 2020 Sep 22.

Department of Neurosurgery, Medical School Hannover, Hannover, Germany.

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http://dx.doi.org/10.1002/mds.28251DOI Listing
September 2020

Ethnic Differences Between Hispanics and Non-Hispanic Whites in Neuropsychiatric Symptoms Predict Conversion to Mild Cognitive Impairment.

J Geriatr Psychiatry Neurol 2020 Sep 10:891988720957087. Epub 2020 Sep 10.

Division of Biostatistics and Epidemiology, Department of Molecular and Translational Medicine, Paul L. Foster School of Medicine, 158161Texas Tech University Health Sciences Center El Paso, TX, USA.

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http://dx.doi.org/10.1177/0891988720957087DOI Listing
September 2020

Progressive Ataxia with Hemiplegic Migraines: a Phenotype of CACNA1A Missense Mutations, Not CAG Repeat Expansions.

Cerebellum 2020 Sep 5. Epub 2020 Sep 5.

Consultorio y Laboratorio de Neurogenética, Centro Universitario de Neurología José María Ramos Mejía, Buenos Aires, Argentina.

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http://dx.doi.org/10.1007/s12311-020-01185-9DOI Listing
September 2020

Long duration response in Parkinson's disease: levodopa revisited.

Brain 2020 Aug;143(8):2332-2335

James J and Joan A Gardner Center for Parkinson's Disease and Movement Disorders, University of Cincinnati, Cincinnati, Ohio, USA.

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http://dx.doi.org/10.1093/brain/awaa226DOI Listing
August 2020

Implementation of Mobile Health Technologies in Clinical Trials of Movement Disorders: Underutilized Potential.

Neurotherapeutics 2020 Jul 30. Epub 2020 Jul 30.

Gardner Family Center for Parkinson's disease and Movement Disorders, Department of Neurology, University of Cincinnati Academic Health Center, 260 Stetson St., Suite 2300, Cincinnati, OH, 45267-0525, USA.

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http://dx.doi.org/10.1007/s13311-020-00901-xDOI Listing
July 2020

Initiating pharmacotherapy in early Parkinson's disease.

Lancet Neurol 2020 08;19(8):643-644

Edmond J Safra Program in Parkinson's Disease and the Morton and Gloria Shulman Movement Disorders Clinic, Toronto Western Hospital, UHN, Division of Neurology, University of Toronto, Toronto, ON M5T 2S8, Canada.

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http://dx.doi.org/10.1016/S1474-4422(20)30225-8DOI Listing
August 2020

The Choice Between Advanced Therapies for Parkinson's Disease Patients: Why, What, and When?

J Parkinsons Dis 2020 ;10(s1):S65-S73

Department of Neurology, Amsterdam UMC, University of Amsterdam, Amsterdam Neuroscience, Amsterdam, Netherlands.

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http://dx.doi.org/10.3233/JPD-202104DOI Listing
January 2020

Value of Clinical Signs in Identifying Patients with Scans without Evidence of Dopaminergic Deficit (SWEDD).

J Parkinsons Dis 2020 Jun 25. Epub 2020 Jun 25.

Department of Neurology, Amsterdam University Medical Centers, University of Amsterdam, Meibergdreef 9, Amsterdam, The Netherlands.

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http://dx.doi.org/10.3233/JPD-202090DOI Listing
June 2020

variants in REM sleep behavior disorder: A multicenter study.

Neurology 2020 08 26;95(8):e1008-e1016. Epub 2020 Jun 26.

From the Department of Human Genetics (L.K., U.R., G.A.R., Z.G.-O.), Montreal Neurological Institute (L.K., J.A.R., U.R., E.L., F.A., R.B.P., G.A.R., Z.G.-O.), and Department of Neurology and Neurosurgery (J.A.R., F.A., R.B.P., G.A.R., Z.G.-O.), McGill University, Montréal; Oxford Parkinson's Disease Centre (M.T.M.H.) and Nuffield Department of Clinical Neurosciences (M.T.M.H.), University of Oxford, UK; Sleep Disorders Unit (I.A.), Pitié Salpêtrière Hospital, Centre de Recherche de l'Institut du Cerveau et de la Moelle Epinière and Sorbonne Universities, Paris; National Reference Center for Narcolepsy, Sleep Unit (Y.D.), Department of Neurology, Gui-de-Chauliac Hospital, CHU Montpellier, University of Montpellier, Inserm U1061, France; Sleep Disorders Unit, Department of Neurology (B.H., A.S.), Medical University of Innsbruck, Austria; Department of Clinical Neurophysiology and Sleep Center (C.C.M.), University Lille North of France, CHU Lille; Sleep Disorder Unit (B.A.), Carémeau Hospital, University Hospital of Nîmes, France; Department of Biomedical and Neuromotor Sciences (DIBINEM) (G.P., E.A.), Alma Mater Studiorum, University of Bologna; IRCCS (G.P., E.A.), Istituto delle Scienze Neurologiche, Bologna; Department of Neurological Sciences (L.F.-S.), Università Vita-Salute San Raffaele, Milan, Italy; Department of Neurology with Institute of Translational Neurology (A.H.), University of Muenster, Germany; Department of Neurology (B.F.B.), Mayo Clinic, Rochester, MN; UC Gardner Neuroscience Institute and Gardner Family Center for Parkinson's Disease and Movement Disorders (A.J.E.), Cincinnati, OH; Sleep and Neurology Unit (V.C.D.C.), Beau Soleil Clinic, Montpellier; EuroMov (V.C.D.C.), University of Montpellier, France; Paracelsus-Elena-Klinik (B.M., F.S.-D., C.T.), Kassel; Department of Neurology (B.M., C.T.), University Medical Centre Goettingen; Department of Neurology (F.S.-D., W.O.), Philipps University, Marburg, Germany; Department of Neurology and Centre of Clinical Neuroscience (K.S., D.K.), Charles University, First Faculty of Medicine and General University Hospital, Prague, Czech Republic; Department of Medical Sciences and Public Health, Sleep Disorder Research Center (M.F., M.P.), University of Cagliari, Italy; Laboratory for Sleep Disorders (F.D., M.V.) and Department of Neurology (F.D., M.V.), St. Dimpna Regional Hospital, Geel, Belgium; Department of Medicine (DAME) (M.T., M.V.), University of Udine, Italy; Department of Clinical and Movement Neurosciences (M.T.), UCL Queen Square Institute of Neurology, London, UK; Clinical Neurology Unit (G.L.G., M.V.), Department of Neurosciences, University Hospital of Udine; DMIF (G.L.G.), University of Udine, Italy; Centre d'Études Avancées en Médecine du Sommeil (J.-F.G., A.D., J.Y.M., R.B.P.), Hôpital du Sacré-Cœur de Montréal; and Departments of Psychology (J.-F.G.), Neurosciences (A.D.), and Psychiatry (J.Y.M.), Université du Québec à Montréal, Canada.

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http://dx.doi.org/10.1212/WNL.0000000000010042DOI Listing
August 2020

Development and Validation of the Orthostatic Tremor Severity and Disability Scale (OT-10).

Mov Disord 2020 Oct 20;35(10):1796-1801. Epub 2020 Jun 20.

Gardner Family Center for Parkinson's Disease and Movement Disorders, Department of Neurology, University of Cincinnati, Cincinnati, Ohio, USA.

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http://dx.doi.org/10.1002/mds.28142DOI Listing
October 2020

Skin Cancer May Delay Onset but Not Progression of Parkinson's Disease: A Nested Case-Control Study.

Front Neurol 2020 28;11:406. Epub 2020 May 28.

Department of Neurology, James J. and Joan A. Gardner Center for Parkinson's Disease and Movement Disorders, University of Cincinnati, Cincinnati, OH, United States.

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http://dx.doi.org/10.3389/fneur.2020.00406DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7270344PMC
May 2020

When does postural instability appear in monogenic parkinsonisms? An individual-patient meta-analysis.

J Neurol 2020 May 20. Epub 2020 May 20.

Department of Neurology, Gardner Family Center for Parkinson's Disease and Movement Disorders, University 6 of Cincinnati, Cincinnati, OH, USA.

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http://dx.doi.org/10.1007/s00415-020-09892-3DOI Listing
May 2020

Disentangling the Amyloid Pathways: A Mechanistic Approach to Etiology.

Front Neurosci 2020 21;14:256. Epub 2020 Apr 21.

Department of Laboratory Medicine, Clinical Research Center, Karolinska Institutet, Stockholm, Sweden.

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http://dx.doi.org/10.3389/fnins.2020.00256DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7186396PMC
April 2020

Variants in the Niemann-Pick type C gene NPC1 are not associated with Parkinson's disease.

Neurobiol Aging 2020 Sep 8;93:143.e1-143.e4. Epub 2020 Apr 8.

Montreal Neurological Institute, McGill University, Montréal, Quebec, Canada; Department of Neurology and neurosurgery, McGill University, Montréal, Quebec, Canada; Department of Human Genetics, McGill University, Montréal, Quebec, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.neurobiolaging.2020.03.021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7302975PMC
September 2020

Improving anxiety in Parkinson's disease: A cautionary tale about mobile health technologies.

Parkinsonism Relat Disord 2020 04 17;73:50-51. Epub 2020 Mar 17.

Department of Neurology, University of Louisville, Louisville, KY, USA; Northwestern University Feinberg School of Medicine, Chicago, IL, USA. Electronic address:

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http://dx.doi.org/10.1016/j.parkreldis.2020.03.010DOI Listing
April 2020

Thalamic Deep Brain Stimulation for tremor: The critical role of intraoperative testing.

Parkinsonism Relat Disord 2020 04 25;73:45-49. Epub 2020 Mar 25.

The Ohio State Wexner Medical Center, Department of Neurology, Columbus, OH, USA. Electronic address:

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http://dx.doi.org/10.1016/j.parkreldis.2020.03.022DOI Listing
April 2020

Initiation of pharmacological therapy in Parkinson's disease: when, why, and how.

Lancet Neurol 2020 05 12;19(5):452-461. Epub 2020 Mar 12.

Edmond J Safra Program in Parkinson's Disease and the Morton and Gloria Shulman Movement Disorders Clinic, Toronto Western Hospital, UHN, Division of Neurology, University of Toronto, Toronto, ON, Canada. Electronic address:

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http://dx.doi.org/10.1016/S1474-4422(20)30036-3DOI Listing
May 2020

Disease modification and biomarker development in Parkinson disease: Revision or reconstruction?

Neurology 2020 03 26;94(11):481-494. Epub 2020 Feb 26.

From the Department of Neurology (A.J.E.), James J. and Joan A. Gardner Family Center for Parkinson's Disease and Movement Disorders, University of Cincinnati, OH; Edmond J. Safra Program in Parkinson's Disease (L.V.K.), Krembil Research Institute, Toronto Western Hospital, Ontario, Canada; Department of Neurology and Neurosurgery (Z.G.-O.), Montreal Neurological Institute, and Department of Human Genetics (Z.G.-O.), McGill University, Montreal, Quebec, Canada; Department of Clinical Neurosciences (C.H.W.-G.), John van Geest Centre for Brain Repair, University of Cambridge, UK; Division of Medical Oncology and Hematology (P.L.B.), Princess Margaret Cancer Centre, University Health Network, and Department of Medicine (P.L.B.), University of Toronto, Ontario, Canada; Departments of Medicine (S.M.R.), Pediatrics (S.M.R.), Cell Developmental and Integrative Biology (S.M.R.), and Neurology (D.G.S.), University of Alabama at Birmingham; Department of Clinical and Experimental Medicine (F.M.), University of Messina, Italy; Institute of Molecular and Clinical Sciences (F.M.), St George's University of London, UK; Edmond J. Safra Program in Parkinson's Disease (A.F., A.P.S., A.E.L.), Morton and Gloria Shulman Movement Disorders Clinic, Toronto Western Hospital, University of Toronto; Krembil Research Institute (A.F., A.P.S., A.E.L.); Tomorrow Edition (B.S.), Toronto, Ontario, Canada; Consultorio y Laboratorio de Neurogenética (M.A.K.), Centro Universitario de Neurología "José María Ramos Mejía" y División Neurología, Hospital JM Ramos Mejía, Facultad de Medicina, UBA; Programa de Medicina de Precision y Genomica Clinica (M.A.K.), Instituto de Investigaciones en Medicina Traslacional, Facultad de Ciencias Biomédicas, Universidad Austral-CONICET, Buenos Aires, Argentina; Clinical Genomics Program (M.J.F.), Norman Fixel Institute for Neurological Diseases, McKnight Brain Institute, University of Florida Clinical and Translational Science Institute, Gainesville; Clinical Trials Statistical & Data Management Center (C.S.C.), University of Iowa College of Public Health, Iowa City; Department of Neurology (M.A.S.), Massachusetts General Hospital, Boston; Michael J. Fox Foundation for Parkinson's Research (T.S.), New York City, NY; Department of Neurology (R.B.P.), Montreal General Hospital, Quebec; Research Imaging Centre (A.P.S.), Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, University of Toronto, Ontario, Canada; Laboratory of Neurogenetics (A.B.S.), National Institute on Aging, NIH, Bethesda, MD; Department of Clinical Neurosciences (R.A.B.), John van Geest Centre for Brain Repair, WT-MRC Cambridge Stem Cell Institute, University of Cambridge, UK; Clinical Trials Coordination Center (K.K.), University of Rochester Medical Center, NY; Department of Neurology and Neuroscience (C.W.O.), Mount Sinai School of Medicine, New York, NY; Clintrex LLC (C.W.O.), Sarasota, FL; Division of Neurosurgery (A.L.), Krembil Neuroscience Institute, Toronto Western Hospital, Ontario, Canada; Department of Neurological Sciences (J.H.K.), Rush University Medical Center, Chicago, IL; Coeruleus Clinical Sciences (J.M.C.), Woodbridge, CT; and Center for Neurodegenerative Science (P.B.), Van Andel Institute, Grand Rapids, MI.

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http://dx.doi.org/10.1212/WNL.0000000000009107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7220234PMC
March 2020

Teaching NeuroImages: The dentate sign in subacute cerebellar ataxia: Metronidazole neurotoxicity.

Neurology 2020 02 7;94(8):e878-e879. Epub 2020 Feb 7.

From CETRAM (M.T.J., P.S.G.), Santiago de Chile; and Department of Neurology (A.J.E.), UC Gardner Neuroscience Institute, Gardner Center for Parkinson's Disease and Movement Disorders, University of Cincinnati, OH.

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http://dx.doi.org/10.1212/WNL.0000000000009006DOI Listing
February 2020

Impaired Saccade Adaptation in Tremor-Dominant Cervical Dystonia-Evidence for Maladaptive Cerebellum.

Cerebellum 2020 Jan 22. Epub 2020 Jan 22.

Department of Biomedical Engineering, Case Western Reserve University, Cleveland, OH, USA.

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http://dx.doi.org/10.1007/s12311-020-01104-yDOI Listing
January 2020

Safety and Efficacy of RimabotulinumtoxinB for Treatment of Sialorrhea in Adults: A Randomized Clinical Trial.

JAMA Neurol 2020 04;77(4):461-469

James J. and Joan A. Gardner Family Center for Parkinson's Disease and Movement Disorders, University of Cincinnati, Cincinnati, Ohio.

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http://dx.doi.org/10.1001/jamaneurol.2019.4565DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6990829PMC
April 2020

Movement Disorders in Prionopathies: A Systematic Review.

Tremor Other Hyperkinet Mov (N Y) 2019 12;9. Epub 2019 Dec 12.

James J. and Joan A. Gardner Center for Parkinson Disease and Movement Disorders, Department of Neurology and Rehabilitation Medicine, University of Cincinnati, Cincinnati, OH, USA.

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http://dx.doi.org/10.7916/tohm.v0.712DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6925394PMC
September 2020

Acute readmission following deep brain stimulation surgery for Parkinson's disease: A nationwide analysis.

Parkinsonism Relat Disord 2020 01 19;70:96-102. Epub 2019 Dec 19.

Department of Neurology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA; Department of Biostatistics, Epidemiology and Informatics, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.parkreldis.2019.11.023DOI Listing
January 2020

The Narrowing Path for Nilotinib and Other Potential Disease-Modifying Therapies for Parkinson Disease.

JAMA Neurol 2020 Mar;77(3):295-297

Department of Neurology, University of Florida College of Medicine, Gainesville.

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http://dx.doi.org/10.1001/jamaneurol.2019.3983DOI Listing
March 2020

Clinical and neural responses to cognitive behavioral therapy for functional tremor.

Neurology 2019 11 4;93(19):e1787-e1798. Epub 2019 Oct 4.

From the Gardner Family Center for Parkinson's Disease and Movement Disorders (A.J.E., E.N.); Mood Disorders Center (S.R., L.R.W.), University of Cincinnati Gardner Neuroscience Institute; Pediatric Neuroimaging Research Consortium (T.M., J.V.), Cincinnati Children's Hospital; Department of Pediatrics (J.V.), University of Cincinnati College of Medicine, OH; Department of Biomedical Sciences (A.K.D.), Paul L. Foster School of Medicine, Texas Tech University Health Sciences Center, El Paso; Department of Neurology (J.B.A., J.P.S.), University of Alabama at Birmingham; Division of Neuropsychiatry and Behavioral Neurology (W.C.L.), Rhode Island Hospital, Providence; and Edmond J. Safra Program in Parkinson's Disease and Morton and Gloria Shulman Movement Disorders Clinic (A.E.L.), Toronto Western Hospital, University of Toronto, Ontario, Canada.

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http://dx.doi.org/10.1212/WNL.0000000000008442DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6946484PMC
November 2019

Teaching Video NeuroImages: Slow periodic myoclonus in subacute sclerosing panencephalitis and fulminant Wilson disease.

Neurology 2019 10;93(14):e1410-e1411

From the Neurology Service (R.M.M., H.S., J.C., M.R.), Hospital Regional Docente de Trujillo, Peru; Postgraduate Institute of Medical Education and Research (V.L.), Chandigarh, India; and UC Gardner Neuroscience Institute and Gardner Family Center for Parkinson's Disease and Movement Disorders (A.J.E.), Department of Neurology, University of Cincinnati, OH.

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http://dx.doi.org/10.1212/WNL.0000000000008206DOI Listing
October 2019

Internal Versus External Frame of Reference in Functional Movement Disorders.

J Neuropsychiatry Clin Neurosci 2020 30;32(1):67-72. Epub 2019 Sep 30.

The Department of Neurology, Gardner Family Center for Parkinson's Disease and Movement Disorders, University of Cincinnati, Cincinnati, Ohio. (Vizcarra, Hacker, Lopez-Castellanos, Ryes, Laub, Marsili, Espay); the Department of Biomedical Sciences, Division of Biostatistics and Epidemiology, Texas Tech University Health Sciences Center, El Paso, Tex. (Dwivedi); and the Department of Neurology, Division of Movement Disorders, University of Louisville, Louisville, Ky. (LaFaver).

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http://dx.doi.org/10.1176/appi.neuropsych.18110290DOI Listing
October 2020

Tics and functional tic-like movements: Can we tell them apart?

Neurology 2019 10 24;93(17):750-758. Epub 2019 Sep 24.

From the Department of Neurology (C.G.), Charité University Medicine Berlin, Germany; Department of Clinical Neurosciences (D.M.), Cumming School of Medicine, University of Calgary and Hotchkiss Brain Institute, AB, Canada; Department of Neurology (A.J.E.), James J. and Joan A. Gardner Family Center for Parkinson's Disease and Movement Disorders, University of Cincinnati, OH; Division of Neurology (A.E.L.), Edmond J. Safra Program in Parkinson's Disease Morton and Gloria Shulman Movement Disorders Clinic, Toronto Western Hospital-UHN, University of Toronto, ON, Canada; Department of Clinical and Movement Neurosciences (K.P.B.), Queen Square Institute of Neurology, University College London; and Neurosciences Research Centre (M.E.), Molecular and Clinical Sciences Institute, St George's University of London.

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http://dx.doi.org/10.1212/WNL.0000000000008372DOI Listing
October 2019

ADCY5-Related Dyskinesia: Improving Clinical Detection of an Evolving Disorder.

Mov Disord Clin Pract 2019 Sep 19;6(7):512-520. Epub 2019 Aug 19.

Department of Neurology (J.S.), Kingston General Hospital, Canada; Department of Neurology (D.M.-G.), Hospital Universitario Virgen del Rocío, Seville, Spain; and UC Gardner Neuroscience Institute and Gardner Family Center for Parkinson's Disease and Movement Disorders (A.Z., A.J.E.), Department of Neurology University of Cincinnati Ohio USA.

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http://dx.doi.org/10.1002/mdc3.12816DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6749814PMC
September 2019

Sex differences by design and outcome in the Safety of Urate Elevation in PD (SURE-PD) trial.

Neurology 2019 10 4;93(14):e1328-e1338. Epub 2019 Sep 4.

From the Departments of Neurology (M.A.S., R.B., S.B., R.L., A.Y.H., G.B.) and Medicine (E.A.M.), Massachusetts General Hospital, Boston; University of Cincinnati (A.J.E.), OH; Rush University (C.G.G.), Chicago, IL; Michigan State University (J.L.G.), East Lansing; Struthers Parkinson's Center (S.A.P.), Minneapolis, MN; Boston University (M.H.S.-H.), MA; University of Rochester (A.R.), NY; University of Miami (J.M.H.), FL; Brigham and Women's Hospital (G.C.C.), Boston, MA; Yale University School of Medicine (D.S.R.), New Haven, CT; and Department of Nutrition (A.A.), Harvard School of Public Health, Boston, MA.

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http://dx.doi.org/10.1212/WNL.0000000000008194DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6814412PMC
October 2019

Orthostatic hypotension and dementia incidence: links and implications.

Neuropsychiatr Dis Treat 2019 2;15:2181-2194. Epub 2019 Aug 2.

Hurvitz Brain Sciences Program, Sunnybrook Research Institute, University of Toronto, Toronto, ON, Canada.

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http://dx.doi.org/10.2147/NDT.S182123DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6683958PMC
August 2019

Dystonia in atypical parkinsonian disorders.

Parkinsonism Relat Disord 2019 09 23;66:25-33. Epub 2019 Jul 23.

Department of Neurology, Santa Maria University Hospital, Terni, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.parkreldis.2019.07.030DOI Listing
September 2019

Hallucinations, somatic-functional disorders of PD-DLB as expressions of thalamic dysfunction.

Mov Disord 2019 08 15;34(8):1100-1111. Epub 2019 Jul 15.

Department of Neuroscience, Imaging and Clinical Sciences, University G. d'Annunzio of Chieti-Pescara, Italy.

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http://dx.doi.org/10.1002/mds.27781DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6707070PMC
August 2019

The "broken wishbone" splenial sign: A diagnostic hallmark for SPG54 spastic ataxia.

J Neurol Sci 2019 Aug 13;403:114-116. Epub 2019 Jun 13.

Gardner Family Center for Parkinson's Disease and Movement Disorders, Department of Neurology, University of Cincinnati, Cincinnati, OH, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jns.2019.06.012DOI Listing
August 2019

Functional movement disorders in neurogeriatric inpatients : Underdiagnosed, often comorbid to neurodegenerative disorders and treatable.

Z Gerontol Geriatr 2019 Jul 28;52(4):324-329. Epub 2019 May 28.

Department of Neurology, University Hospital Schleswig Holstein, Campus Kiel, Christian-Albrechts-University, Arnold-Heller-Str. 3, Haus 41, 24105, Kiel, Germany.

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http://dx.doi.org/10.1007/s00391-019-01562-yDOI Listing
July 2019

Lack of independent mood-enhancing effect for dopaminergic medications in early Parkinson's disease.

J Neurol Sci 2019 Jul 16;402:81-85. Epub 2019 May 16.

Department of Neurology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA; Department of Psychiatry, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA; Department of Veterans Affairs, Philadelphia VA Medical Center, Philadelphia, PA, USA.

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http://dx.doi.org/10.1016/j.jns.2019.05.009DOI Listing
July 2019

Hiding in Plain Sight: Functional Neurological Disorders in the News.

J Neuropsychiatry Clin Neurosci 2019 23;31(4):361-367. Epub 2019 May 23.

The Department of Neurology, University Hospital Knappschaftskrankenhaus, Ruhr University Bochum, Bochum, Germany (Popkirov); the Section of Cognitive Neuropsychiatry, Institute of Psychiatry, Psychology and Neuroscience, King's College London (Nicholson); the Department of Neurology, Radboud University Medical Centre, Donders Institute for Brain, Cognition, and Behaviour, Nijmegen, the Netherlands (Bloem); the Institute of Medical and Biomedical Education, St. George's University of London and Atkinson Morley Regional Neuroscience Centre, St. George's University Hospitals NHS Foundation Trust, London (Cock); the Department of Clinical Neurosciences, Western General Hospital, Edinburgh, United Kingdom (Derry); the Department of Neurology, University of Otago, Christchurch, New Zealand (Duncan); the Department of Neurology, Edward B. Bromfield Epilepsy Program, Brigham and Women's Hospital, Harvard Medical School, Boston (Dworetsky); the Institute of Molecular and Clinical Sciences, St. George's University of London (Edwards, Morgante); the Department of Neurology, Gardner Family Center for Parkinson Disease and Movement Disorders, University of Cincinnati (Espay); the Human Motor Control Section, National Institute of Neurological Disorders and Stroke, NIH, Bethesda, Md. (Hallett); the Morton and Gloria Shulman Movement Disorders Clinic and Edmond J. Safra Program in Parkinson's Disease, Toronto Western Hospital, Toronto (Lang); Queen Elizabeth University Hospital, University of Glasgow, Glasgow, United Kingdom (Leach); the Mater Centre for Neurosciences and School of Medicine, University of Queensland, Brisbane, Australia (Lehn); the Institut de Neurosciences des Systèmes, INSERM, Aix-Marseille Université, Marseille, France; the Department of Clinical Neurophysiology, Hôpital de la Timone, Assistance Publique-Hôpitaux de Marseille, Marseille, France (McGonigal); the Department of Clinical and Experimental Medicine, University of Messina, Messina, Italy (Morgante); the Departments of Neurology and Psychiatry, Functional Neurology Research Group, Massachusetts General Hospital, Harvard Medical School, Boston (Perez); the Academic Neurology Unit, University of Sheffield, Royal Hallamshire Hospital, Glossop Road, Sheffield, United Kingdom (Reuber); the Institute of Psychiatry, Psychology and Neuroscience, Kings College London (Richardson); the Department of Neurology, Alan Richens Epilepsy Unit, University Hospital of Wales, Cardiff, United Kingdom (Smith); the HYGEIA Hospital, Athens, Greece (Stamelou); the Neurology Clinic, Philipps University Marburg, Marburg, Germany (Stamelou); the University of Athens, Greece (Stamelou); the Department of Neurology, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands (Tijssen); the Neurology Unit, Movement Disorders Division, University of Verona, Verona, Italy (Tinazzi); and the Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, United Kingdom (Carson, Stone).

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https://psychiatryonline.org/doi/10.1176/appi.neuropsych.190
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http://dx.doi.org/10.1176/appi.neuropsych.19010025DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7291360PMC
March 2020

The Final Nail in the Coffin of Disease Modification for Dopaminergic Therapies: The LEAP Trial.

Authors:
Alberto J Espay

JAMA Neurol 2019 07;76(7):747-748

UC Gardner Neuroscience Institute and Gardner Family Center for Parkinson's Disease and Movement Disorders, Department of Neurology, University of Cincinnati, Cincinnati, Ohio.

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http://dx.doi.org/10.1001/jamaneurol.2019.0974DOI Listing
July 2019

Reply to 'Neuropathological progression of clinical Parkinson disease subtypes'.

Nat Rev Neurol 2019 06;15(6):361-362

Morton and Gloria Shulman Movement Disorders Centre and the Edmond J. Safra Program in Parkinson's Disease, Toronto Western Hospital, University of Toronto, Ontario, Canada.

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http://dx.doi.org/10.1038/s41582-019-0198-9DOI Listing
June 2019

Should neurologists diagnose and manage functional neurologic disorders? It is complicated.

Neurol Clin Pract 2019 Apr;9(2):165-167

Department of Neurology (DLP), Functional Neurology Research Group, Cognitive Behavioral Neurology Unit, Massachusetts General Hospital, Harvard Medical School; Department of Psychiatry (DLP), Neuropsychiatry Unit, Massachusetts General Hospital, Harvard Medical School, Boston; Athinoula A. Martinos Center for Biomedical Imaging (DLP), Massachusetts General Hospital, Harvard Medical School, Charlestown; Fort Wayne Neurological Center (ALH), Fort Wayne; Department of Neurology (ALH), Indiana University School of Medicine, Indianapolis; and Department of Neurology (AJE), University of Cincinnati Medical Center, OH.

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http://dx.doi.org/10.1212/CPJ.0000000000000573DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6461419PMC
April 2019

Head tremor at disease onset: an ataxic phenotype of cervical dystonia.

J Neurol 2019 Aug 26;266(8):1844-1851. Epub 2019 Apr 26.

Department of Neurology, Gardner Family Center for Parkinson's Disease and Movement Disorders, University of Cincinnati, Cincinnati, OH, USA.

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http://dx.doi.org/10.1007/s00415-019-09341-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6642013PMC
August 2019

Globular Glial Tauopathy May be Mistaken for Corticobasal Syndrome-Pointers for the Clinician.

Mov Disord Clin Pract 2018 Jul-Aug;5(4):439-441. Epub 2018 Jul 19.

Gardner Family Center for Parkinson's Disease and Movement Disorders, Department of Neurology University of Cincinnati Cincinnati OH USA.

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http://dx.doi.org/10.1002/mdc3.12634DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6336378PMC
July 2018

Clinical Parkinson disease subtyping does not predict pathology.

Nat Rev Neurol 2019 04;15(4):189-190

Morton and Gloria Shulman Movement Disorders Centre and the Edmond J. Safra Program in Parkinson's Disease, Toronto Western Hospital, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1038/s41582-019-0153-9DOI Listing
April 2019

OnabotulinumtoxinA and cognitive behavioral therapy in functional dystonia: A pilot randomized clinical trial.

Parkinsonism Relat Disord 2019 06 13;63:174-178. Epub 2019 Feb 13.

Gardner Family Center for Parkinson's Disease and Movement Disorders, Department of Neurology, University of Cincinnati, Cincinnati, OH, USA. Electronic address:

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http://dx.doi.org/10.1016/j.parkreldis.2019.02.009DOI Listing
June 2019

Holmes Tremor-Like Phenotype in DYT1 Dystonia.

Mov Disord Clin Pract 2018 Mar-Apr;5(2):206-208. Epub 2018 Feb 7.

Consultorio y Laboratorio de Neurogenética, Centro Universitario de Neurología "José María Ramos Mejía" y División Neurología, Hospital JM Ramos Mejía, Facultad de Medicina, UBA Argentina.

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http://dx.doi.org/10.1002/mdc3.12585DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6336283PMC
February 2018

Revisiting protein aggregation as pathogenic in sporadic Parkinson and Alzheimer diseases.

Neurology 2019 02;92(7):329-337

From the UC Gardner Neuroscience Institute and Gardner Family Center for Parkinson's Disease and Movement Disorders (A.J.E., J.A.V., L.M., A.M.), Department of Neurology, University of Cincinnati, OH; Edmond J. Safra Program in Parkinson's Disease and the Morton and Gloria Shulman Movement Disorders Clinic (A.E.L., A.F.), Toronto Western Hospital, University of Toronto; Krembil Research Institute (A.E.L., A.F.), Toronto, Canada; Parkinson's Disease and Movement Disorders Center (D.K.S.), Department of Neurology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA; College of Medicine (K.A.J.), Mayo Clinic, Rochester, MN; Institute of Molecular and Clinical Sciences (F.M.), St George's University of London, UK; Division of Movement Disorders (R.S.), Department of Neurology and Department of Health Science Research, Mayo Clinic College of Medicine, Rochester, MN; Department of Neurology and the Pittsburgh Institute for Neurodegenerative Diseases (J.T.G., F.C.), University of Pittsburgh, PA; Department of Neurology (T.R.Y.), University of Kentucky, Lexington; Parkinson's Disease Research, Education and Clinical Center (C.M.T.), Neurology, San Francisco Veterans Affairs Medical Center; Department of Neurology (C.M.T.), University of California-San Francisco; Department of Neurology & Neurosurgery, Montreal Neurological Institute, and Department of Human Genetics (Z.G.-O.), McGill University, Canada; Parkinson & Other Movement Disorders Center UC San Diego (I.L.), Department of Neurosciences, Altman Clinical Translational Research Institute, La Jolla, CA; VA Puget Sound Health Care System and Department of Neurology (I.F.M., CP.Z.), University of Washington, Seattle; Department of Neurology (I.F.M.), University of Washington School of Medicine, Seattle; Center for Neurodegenerative Science (P.B.), Van Andel Research Institute, Grand Rapids, MI; Center for Neurological Restoration (H.H.F.) and Lou Ruvo Center for Brain Health, Neurological Institute (J.B.L.), Cleveland Clinic, OH; Department of Neurology (D.G.S.), University of Alabama at Birmingham; Consultorio y Laboratorio de Neurogenética (M.A.K.), Centro Universitario de Neurología "José María Ramos Mejía" y División Neurología, Hospital JM Ramos Mejía, Facultad de Medicina, UBA; Programa de Medicina de Precision y Genomica Clinica (M.A.K.), Instituto de Investigaciones en Medicina Traslacional, Facultad de Ciencias Biomédicas, Universidad Austral-CONICET, Buenos Aires, Argentina; Department of Neurology (M.A.S.), Massachusetts General Hospital, Boston; Division of Neuroscience (S.P.S.), Sanofi-Genzyme, Framingham, MA; Michael J. Fox Foundation for Parkinson's Research (T.S.), New York, NY; and College of Sciences (G.P.), University of Texas at San Antonio.

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http://dx.doi.org/10.1212/WNL.0000000000006926DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6382364PMC
February 2019

Movement Disorders in Metabolic Disorders.

Curr Neurol Neurosci Rep 2019 02 9;19(2). Epub 2019 Feb 9.

Gardner Neuroscience Institute, Gardner Center for Parkinson's Disease and Movement Disorders, University of Cincinnati, Cincinnati, OH, USA.

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http://dx.doi.org/10.1007/s11910-019-0921-3DOI Listing
February 2019

Effect of subthalamic deep brain stimulation on posture in Parkinson's disease: A blind computerized analysis.

Parkinsonism Relat Disord 2019 05 8;62:122-127. Epub 2019 Jan 8.

Gardner Family Center for Parkinson's Disease and Movement Disorders, Department of Neurology, University of Cincinnati, Cincinnati, OH, USA.

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http://dx.doi.org/10.1016/j.parkreldis.2019.01.003DOI Listing
May 2019

Parkinson Diseases in the 2020s and Beyond: Replacing Clinico-Pathologic Convergence With Systems Biology Divergence.

J Parkinsons Dis 2018 ;8(s1):S59-S64

The Edmond J. Safra Program in Parkinson's Disease and the Morton and Gloria Shulman Movement Disorders Clinic, University Health Network, University of Toronto, Toronto, Canada.

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http://dx.doi.org/10.3233/JPD-181465DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6311362PMC
October 2019

Soft signs in movement disorders: friends or foes?

J Neurol Neurosurg Psychiatry 2019 08 8;90(8):961-962. Epub 2018 Nov 8.

Edmond J. Safra Program in Parkinson's Disease, Morton and Gloria Shulman Movement Disorders Clinic, Toronto Western Hospital - UHN, Division of Neurology, University of Toronto, Toronto, Ontario, Canada

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http://jnnp.bmj.com/lookup/doi/10.1136/jnnp-2018-318455
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http://dx.doi.org/10.1136/jnnp-2018-318455DOI Listing
August 2019

Q&A with Alberto Espay.

Authors:
Alberto J Espay

Mov Disord 2018 10;33(10):1561-1563

Department of Neurology, University of Cincinnati, Cincinnati, Ohio, USA.

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http://doi.wiley.com/10.1002/mds.27531
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http://dx.doi.org/10.1002/mds.27531DOI Listing
October 2018

Levodopa-induced dyskinesia in Parkinson disease: Current and evolving concepts.

Ann Neurol 2018 12 30;84(6):797-811. Epub 2018 Nov 30.

Edmond J. Safra Program in Parkinson's Disease, Morton and Gloria Shulman Movement Disorders Clinic, Toronto Western Hospital, University Health Network, Division of Neurology, University of Toronto, Toronto, Ontario, Canada.

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http://doi.wiley.com/10.1002/ana.25364
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http://dx.doi.org/10.1002/ana.25364DOI Listing
December 2018

Technology-based assessment of motor and nonmotor phenomena in Parkinson disease.

Expert Rev Neurother 2018 Nov 8;18(11):825-845. Epub 2018 Oct 8.

a James J and Joan A Gardner Family Center for Parkinson's Disease and Movement Disorders, Department of Neurology , University of Cincinnati , Cincinnati , OH , USA.

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https://www.tandfonline.com/doi/full/10.1080/14737175.2018.1
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http://dx.doi.org/10.1080/14737175.2018.1530593DOI Listing
November 2018

Epileptic chorea: Another window into neural networks?

J Neurol Sci 2018 11 11;394:138-140. Epub 2018 Sep 11.

James J. and Joan A. Gardner Center for Parkinson disease and Movement Disorders, Department of Neurology and Rehabilitation Medicine, University of Cincinnati, Cincinnati, OH, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S0022510X183037
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http://dx.doi.org/10.1016/j.jns.2018.09.009DOI Listing
November 2018

Teaching Video NeuroImages: The signs of dystonic tremor: Tremulous "escanciador".

Neurology 2018 09;91(12):e1204-e1205

From the Department of Neurology (J.S.), Kingston General Hospital, Canada; Department of Neurology (D.M.-G.), Hospital Universitario Virgen del Rocío, Seville, Spain; and UC Gardner Neuroscience Institute and Gardner Family Center for Parkinson's Disease and Movement Disorders (A.Z., A.J.E.), Department of Neurology, University of Cincinnati, OH.

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http://dx.doi.org/10.1212/WNL.0000000000006215DOI Listing
September 2018

Telemedicine in Neurological Disorders: Opportunities and Challenges.

Telemed J E Health 2019 07 23;25(7):541-550. Epub 2018 Aug 23.

3 Department of Neurology and Rehabilitation Medicine, Gardner Family Center for Parkinson's Disease and Movement Disorders, University of Cincinnati, Cincinnati, Ohio.

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http://dx.doi.org/10.1089/tmj.2018.0101DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6664824PMC
July 2019

Coxa saltans misdiagnosed as functional gait disorder: Two cases.

Neurology 2018 08;91(6):276-277

From the Division of Neurology, Department of Pediatrics (D.L.G., S.W.W.), Cincinnati Children's Hospital Medical Center and University of Cincinnati; and Department of Neurology (A.J.E.), Gardner Center for Parkinson's Disease and Movement Disorders, UC Gardner Neuroscience Institute, University of Cincinnati, OH.

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http://dx.doi.org/10.1212/WNL.0000000000005955DOI Listing
August 2018

Reverse blood pressure dipping as marker of dysautonomia in Parkinson disease.

Parkinsonism Relat Disord 2018 11 28;56:82-87. Epub 2018 Jun 28.

Department of Medical Sciences, Autonomic Unit and Hypertension Unit, University of Turin, Città Della Salute e Della Scienza Hospital, Turin, Italy. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S13538020183030
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http://dx.doi.org/10.1016/j.parkreldis.2018.06.032DOI Listing
November 2018

Subthalamic deep brain stimulation and levodopa in Parkinson's disease: a meta-analysis of combined effects.

J Neurol 2019 Feb 16;266(2):289-297. Epub 2018 Jun 16.

Department of Neurology, Gardner Family Center for Parkinson's Disease and Movement Disorders, University of Cincinnati, 260 Stetson St, Suite 2300, Cincinnati, OH, 45267-0525, USA.

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http://dx.doi.org/10.1007/s00415-018-8936-2DOI Listing
February 2019

Movement disorders in non-encephalopathic Hashimoto's thyroiditis.

Parkinsonism Relat Disord 2018 10 5;55:141-142. Epub 2018 Jun 5.

Edmond J. Safra Program in Parkinson's Disease and the Morton and Gloria Shulman Movement Disorders Clinic, Toronto Western Hospital, Toronto, ON, Canada.

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http://dx.doi.org/10.1016/j.parkreldis.2018.06.008DOI Listing
October 2018

Current Concepts in Diagnosis and Treatment of Functional Neurological Disorders.

JAMA Neurol 2018 09;75(9):1132-1141

Motor Control and Movement Disorders Group, Institute of Molecular and Clinical Sciences, St George's University of London, London, United Kingdom.

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http://dx.doi.org/10.1001/jamaneurol.2018.1264DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7293766PMC
September 2018

Dopaminergic dose adjustment and negative affective symptoms after deep brain stimulation.

J Neurol Sci 2018 07 7;390:33-35. Epub 2018 Apr 7.

Gardner Family Center for Parkinson's Disease and Movement Disorders, Department of Neurology, University of Cincinnati, Cincinnati, Ohio, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jns.2018.04.002DOI Listing
July 2018

Post-stroke Movement Disorders: The Clinical, Neuroanatomic, and Demographic Portrait of 284 Published Cases.

J Stroke Cerebrovasc Dis 2018 Sep 21;27(9):2388-2397. Epub 2018 May 21.

James J. and Joan A. Gardner Center for Parkinson Disease and Movement Disorders, Department of Neurology and Rehabilitation Medicine, University of Cincinnati, Cincinnati, Ohio. Electronic address:

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http://dx.doi.org/10.1016/j.jstrokecerebrovasdis.2018.04.028DOI Listing
September 2018

Diagnostic criteria for camptocormia in Parkinson's disease: A consensus-based proposal.

Parkinsonism Relat Disord 2018 08 8;53:53-57. Epub 2018 May 8.

Neurology Unit, Movement Disorders Division, Department of Neurosciences, Biomedicine and Movement Sciences, University of Verona, Verona, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.parkreldis.2018.04.033DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7293065PMC
August 2018

Reply to: "Autonomic dysfunction in Parkinson's disease: The hidden game changer?"

Mov Disord 2018 07 14;33(6):1028-1029. Epub 2018 May 14.

Gardner Family Center for Parkinson's Disease and Movement Disorders, Department of Neurology, University of Cincinnati, Cincinnati, Ohio, USA.

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http://dx.doi.org/10.1002/mds.27421DOI Listing
July 2018

Video NeuroImages: Head titubation in anti-mGluR1 autoantibody-associated cerebellitis.

Neurology 2018 04;90(16):746-747

From the Neurology and Ataxia Unit, Department of Neurology (J.L.P., L.A.D., O.G.P.B.), Universidade Federal de São Paulo; Faculdade Israelita de Ciências da Saúde Albert Einstein (L.A.D.), São Paulo, Brazil; Gardner Center for Parkinson's Disease and Movement Disorders (A.J.E.), University of Cincinnati Gardner Neuroscience Institute, OH; and Institute of Neurology (R.H.), Medical University of Vienna, Austria.

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http://dx.doi.org/10.1212/WNL.0000000000005338DOI Listing
April 2018

Disease Modification in Parkinson's Disease: Current Approaches, Challenges, and Future Considerations.

Mov Disord 2018 05 11;33(5):660-677. Epub 2018 Apr 11.

UC Gardner Neuroscience Institute and Gardner Family Center for Parkinson's Disease and Movement Disorders, Department of Neurology, University of Cincinnati, Cincinnati, Ohio, USA.

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http://dx.doi.org/10.1002/mds.27360DOI Listing
May 2018

Small intestinal bacterial overgrowth in Parkinson's disease: Tribulations of a trial.

Parkinsonism Relat Disord 2018 09 4;54:110-112. Epub 2018 Apr 4.

Gardner Family Center for Parkinson's Disease and Movement Disorders, Department of Neurology, University of Cincinnati, Cincinnati, OH, USA. Electronic address:

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http://dx.doi.org/10.1016/j.parkreldis.2018.04.003DOI Listing
September 2018

Functional neurological disorders in Parkinson disease.

J Neurol Neurosurg Psychiatry 2018 06 16;89(6):566-571. Epub 2018 Mar 16.

Department of Neurology, Gardner Family Center for Parkinson's Disease and Movement Disorders, University of Cincinnati, Cincinnati, Ohio, USA.

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http://dx.doi.org/10.1136/jnnp-2017-317378DOI Listing
June 2018