Publications by authors named "Alberto Gulino"

100Publications

KCTD11 tumor suppressor gene expression is reduced in prostate adenocarcinoma.

Biomed Res Int 2014 19;2014:380398. Epub 2014 Jun 19.

Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, Via Vetoio, Coppito 2, 67100 L'Aquila, Italy.

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http://dx.doi.org/10.1155/2014/380398DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4090506PMC
March 2015

Yin-Yang strands of PCAF/Hedgehog axis in cancer control.

Trends Mol Med 2014 Aug 4;20(8):416-8. Epub 2014 Jun 4.

Department of Molecular Medicine, "La Sapienza" University, 00161 Rome, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.molmed.2014.05.003DOI Listing
August 2014

Vemurafenib and panitumumab combination tailored therapy in BRAF-mutated metastatic colorectal cancer: a case report.

Cancer Biol Ther 2014 Jul 22;15(7):826-31. Epub 2014 Apr 22.

Neuromed IRCCS; Pozzilli, Italy; Department of Molecular Medicine; Center for Life Nanoscience@Sapienza; Italian Institute of Technology and Istituto Pasteur; Fondazione Cenci-Bolognetti; Sapienza University of Rome; Rome, Italy.

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http://www.tandfonline.com/doi/abs/10.4161/cbt.28878
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http://dx.doi.org/10.4161/cbt.28878DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4100983PMC
July 2014

High-throughput microRNA profiling of pediatric high-grade gliomas.

Neuro Oncol 2014 Jan 4;16(2):228-40. Epub 2013 Dec 4.

Corresponding author: Elisabetta Ferretti, MD, PhD, Department of Experimental Medicine, Sapienza University, Rome, Italy. Viale Regina Elena, 291 - 00161 Rome, Italy.

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http://dx.doi.org/10.1093/neuonc/not215DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3895388PMC
January 2014

TrkAIII promotes microtubule nucleation and assembly at the centrosome in SH-SY5Y neuroblastoma cells, contributing to an undifferentiated anaplastic phenotype.

Biomed Res Int 2013 6;2013:740187. Epub 2013 Jun 6.

Department of Applied Clinical and Biotechnological Sciences, University of L'Aquila, Via Vetoio, Coppito 2, 67100 L'Aquila, Italy.

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http://dx.doi.org/10.1155/2013/740187DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3690223PMC
December 2013

Control of stem cells and cancer stem cells by Hedgehog signaling: pharmacologic clues from pathway dissection.

Biochem Pharmacol 2013 Mar 10;85(5):623-628. Epub 2012 Nov 10.

Center for Life NanoScience@LaSapienza, Istituto Italiano di Tecnologia, Italy; Department of Molecular Medicine, Sapienza University, 00161 Rome, Italy; Neuromed Institute, 86077 Pozzilli, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.bcp.2012.11.001DOI Listing
March 2013

Nanoparticle-based delivery of small interfering RNA: challenges for cancer therapy.

Int J Nanomedicine 2012 20;7:3637-57. Epub 2012 Jul 20.

Department of Molecular Medicine, Sapienza University of Rome, Rome, Italy.

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http://dx.doi.org/10.2147/IJN.S23696DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3418108PMC
March 2013

Chemotherapy and target therapy in the management of adult high- grade gliomas.

Curr Cancer Drug Targets 2012 Oct;12(8):1016-31

Department of Medical-Surgical Science and Biotechnology, University of Rome Sapienza, Polo Pontino, Latina, Italy.

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http://dx.doi.org/10.2174/156800912803251207DOI Listing
October 2012

CCAAT/enhancer-binding proteins are key regulators of human type two deiodinase expression in a placenta cell line.

Endocrinology 2012 Aug 11;153(8):4030-8. Epub 2012 Jun 11.

Laboratory of Molecular Oncology Department of Molecular Medicine, “Sapienza” University of Rome, I-00161 Rome and I-04100 Latina, Italy.

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http://dx.doi.org/10.1210/en.2011-2113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3404352PMC
August 2012

Alendronate promotes plasmin-mediated MMP-9 inactivation by exposing cryptic plasmin degradation sites within the MMP-9 catalytic domain.

FEBS Lett 2012 Jul 4;586(16):2366-74. Epub 2012 Jun 4.

Section of Molecular Pathology, Department of Experimental Medicine, University of L'Aquila, 67100 L'Aquila, Italy.

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http://dx.doi.org/10.1016/j.febslet.2012.05.048DOI Listing
July 2012

Hedgehog/Gli control by ubiquitination/acetylation interplay.

Vitam Horm 2012 ;88:211-27

Department of Molecular Medicine, Sapienza University, Rome, Italy.

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http://dx.doi.org/10.1016/B978-0-12-394622-5.00009-2DOI Listing
August 2012

The HMGA1 protoncogene frequently deregulated in cancer is a transcriptional target of E2F1.

Mol Carcinog 2013 Jul 2;52(7):526-34. Epub 2012 Mar 2.

Department of Experimental Medicine, Sapienza University, Rome, Italy.

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http://dx.doi.org/10.1002/mc.21887DOI Listing
July 2013

Hedgehog signaling pathway and its targets for treatment in basal cell carcinoma.

J Exp Pharmacol 2012 14;4:173-85. Epub 2012 Dec 14.

Department of Experimental Medicine, Sapienza University of Rome, Rome, Italy.

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http://dx.doi.org/10.2147/JEP.S28553DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4863577PMC
May 2016

Protective effect of pioglitazone, a PPARγ ligand, in a 3 nitropropionic acid model of Huntington's disease.

Brain Res Bull 2011 May 31;85(3-4):231-7. Epub 2011 Mar 31.

University La Sapienza ROME, Department of Molecular Medicine, Viale Regina Elena, 324, 00161 Rome, Italy.

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http://dx.doi.org/10.1016/j.brainresbull.2011.03.011DOI Listing
May 2011

Protected from the inside: endogenous histone deacetylase inhibitors and the road to cancer.

Biochim Biophys Acta 2011 Apr 26;1815(2):241-52. Epub 2011 Jan 26.

Department of Molecular Medicine, Sapienza University, Rome, Italy.

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http://dx.doi.org/10.1016/j.bbcan.2011.01.002DOI Listing
April 2011

MYCN sensitizes human neuroblastoma to apoptosis by HIPK2 activation through a DNA damage response.

Mol Cancer Res 2011 Jan 20;9(1):67-77. Epub 2010 Dec 20.

Department of Experimental Medicine, Sapienza University of Rome, Policlinico Umberto I, Viale Regina Elena, 324, 00161, Rome, Italy.

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http://dx.doi.org/10.1158/1541-7786.MCR-10-0227DOI Listing
January 2011

International distribution and age estimation of the Portuguese BRCA2 c.156_157insAlu founder mutation.

Breast Cancer Res Treat 2011 Jun 22;127(3):671-9. Epub 2010 Jul 22.

Department of Genetics, Portuguese Oncology Institute, Rua Dr. António Bernardino de Almeida, Porto 4200-072, Portugal.

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http://dx.doi.org/10.1007/s10549-010-1036-3DOI Listing
June 2011

Vismodegib, a small-molecule inhibitor of the hedgehog pathway for the treatment of advanced cancers.

Curr Opin Investig Drugs 2010 Jun;11(6):707-18

Sapienza University of Rome, Department of Experimental Medicine, Viale Regina Elena 324, 00161 Rome, Italy.

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June 2010

MicroRNAs as biomarkers for CNS cancer and other disorders.

Brain Res 2010 Jun 7;1338:100-11. Epub 2010 Apr 7.

Department of Experimental Medicine, Sapienza University, 324 viale Regina Elena, Rome, Italy.

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http://dx.doi.org/10.1016/j.brainres.2010.03.103DOI Listing
June 2010

The BRCAPRO 5.0 model is a useful tool in genetic counseling and clinical management of male breast cancer cases.

Eur J Hum Genet 2010 Jul 17;18(7):856-8. Epub 2010 Mar 17.

Molecular and Nutritional Epidemiology Unit, Cancer Research and Prevention Institute-ISPO, Florence, Italy.

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http://dx.doi.org/10.1038/ejhg.2010.29DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2987355PMC
July 2010

Hedgehog signalling in colon cancer and stem cells.

EMBO Mol Med 2009 Sep;1(6-7):300-2

Department of Experimental Medicine, Sapienza University, Rome, Italy.

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http://dx.doi.org/10.1002/emmm.200900042DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3378148PMC
September 2009

Cell death or survival: the complex choice of the retinoblastoma tumor suppressor protein.

Cell Cycle 2010 Jan 1;9(1):23-4. Epub 2010 Jan 1.

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January 2010

The multiple functions of Numb.

Exp Cell Res 2010 Apr 26;316(6):900-6. Epub 2009 Nov 26.

Department of Experimental Medicine, Sapienza University, 324 viale Regina Elena, 00161 Rome, Italy.

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http://linkinghub.elsevier.com/retrieve/pii/S001448270900516
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http://dx.doi.org/10.1016/j.yexcr.2009.11.017DOI Listing
April 2010

MiR-128 up-regulation inhibits Reelin and DCX expression and reduces neuroblastoma cell motility and invasiveness.

FASEB J 2009 Dec 27;23(12):4276-87. Epub 2009 Aug 27.

Department of Experimental Medicine and Biochemical Sciences, University of Rome "Tor Vergata," Via Montpellier 1, 00133 Roma, Italy.

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http://dx.doi.org/10.1096/fj.09-134965DOI Listing
December 2009

TORCs/CRTCs: more than mere coincidence.

Cell Cycle 2009 Apr 9;8(7):963-4. Epub 2009 Apr 9.

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April 2009

Glucocorticoids and neonatal brain injury: the hedgehog connection.

J Clin Invest 2009 Feb;119(2):243-6

Department of Experimental Medicine, Sapienza University, Rome, Italy.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2631307PMC
http://dx.doi.org/10.1172/jci38387DOI Listing
February 2009

The coactivator CRTC1 promotes cell proliferation and transformation via AP-1.

Proc Natl Acad Sci U S A 2009 Feb 21;106(5):1445-50. Epub 2009 Jan 21.

Department of Experimental Medicine and Pasteur Institute, Cenci Bolognetti Foundation, Sapienza University, Rome, Italy.

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http://dx.doi.org/10.1073/pnas.0808749106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2635810PMC
February 2009

Hedgehog signaling during expansion of human pancreatic islet-derived precursors.

Ann N Y Acad Sci 2008 Dec;1150:43-5

Diabetes Unit, Department of Internal Medicine, Endocrine and Metabolic Sciences and Biochemistry, University of Siena, Siena, Italy.

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http://dx.doi.org/10.1196/annals.1447.024DOI Listing
December 2008

Pathological and molecular heterogeneity of medulloblastoma.

Curr Opin Oncol 2008 Nov;20(6):668-75

Department of Experimental Medicine, University Sapienza of Rome, Rome, Italy.

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http://dx.doi.org/10.1097/CCO.0b013e32831369f4DOI Listing
November 2008

Notch signaling and diseases: an evolutionary journey from a simple beginning to complex outcomes.

Biochim Biophys Acta 2008 Sep 24;1782(9):489-97. Epub 2008 Jun 24.

Department of Experimental Medicine, Sapienza University of Rome, Roma, Italy.

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http://linkinghub.elsevier.com/retrieve/pii/S092544390800129
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http://dx.doi.org/10.1016/j.bbadis.2008.06.008DOI Listing
September 2008

NF-kB/NOS cross-talk induced by mitochondrial complex II inhibition: implications for Huntington's disease.

Neurosci Lett 2008 Apr 2;434(3):241-6. Epub 2007 Oct 2.

Dipartimento di Medicina Sperimentale, Università La Sapienza, viale Regina Elena, 00161 Rome, Italy.

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http://dx.doi.org/10.1016/j.neulet.2007.09.056DOI Listing
April 2008

Notch and Ikaros: not only converging players in T cell leukemia.

Cell Cycle 2007 Nov 15;6(22):2730-4. Epub 2007 Aug 15.

Department of Experimental Medicine, University La Sapienza, Roma, taly.

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http://dx.doi.org/10.4161/cc.6.22.4894DOI Listing
November 2007

Hedgehog signaling pathway in neural development and disease.

Psychoneuroendocrinology 2007 Aug 9;32 Suppl 1:S52-6. Epub 2007 Jul 9.

Department of Experimental Medicine and Pathology, University La Sapienza, 324 Viale Regina Elena, 00161 Roma, Italy.

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http://dx.doi.org/10.1016/j.psyneuen.2007.03.017DOI Listing
August 2007

The E3 ligase Aip4/Itch ubiquitinates and targets ErbB-4 for degradation.

FASEB J 2007 Sep 26;21(11):2849-62. Epub 2007 Apr 26.

Department of Experimental Medicine and Pathology, University La Sapienza, Viale Regina Elena 324 00161, Rome, Italy.

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http://www.fasebj.org/doi/10.1096/fj.06-7925com
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http://dx.doi.org/10.1096/fj.06-7925comDOI Listing
September 2007

Inhibition of medulloblastoma tumorigenesis by the antiproliferative and pro-differentiative gene PC3.

FASEB J 2007 Jul 19;21(9):2215-25. Epub 2007 Mar 19.

Institute of Neurobiology and Molecular Medicine, Consiglio Nazionale Ricerche, Via Fosso di Fiorano 64, 00143, Rome, Italy.

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http://dx.doi.org/10.1096/fj.06-7548comDOI Listing
July 2007

Multiple ubiquitin-dependent processing pathways regulate hedgehog/gli signaling: implications for cell development and tumorigenesis.

Cell Cycle 2007 Feb 3;6(4):390-3. Epub 2007 Feb 3.

Department of Experimental Medicine and Pathology, Cenci Bolognetti Foundation, University La Sapienza, Roma, Italy.

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http://dx.doi.org/10.4161/cc.6.4.3809DOI Listing
February 2007

Suppressors of hedgehog signaling: Linking aberrant development of neural progenitors and tumorigenesis.

Mol Neurobiol 2006 Dec;34(3):193-204

Department of Experimental Medicine and Pathology, University La Sapienza, Rome, Italy.

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http://link.springer.com/10.1385/MN:34:3:193
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http://dx.doi.org/10.1385/MN:34:3:193DOI Listing
December 2006

TrkAIII expression in the thymus.

J Neuroimmunol 2007 Feb 22;183(1-2):151-61. Epub 2007 Jan 22.

Department of Experimental Medicine, University of L'Aquila, Coppito 2, Via Vetoio, 67100 L'Aquila, Italy.

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http://dx.doi.org/10.1016/j.jneuroim.2006.12.005DOI Listing
February 2007

Numb is a suppressor of Hedgehog signalling and targets Gli1 for Itch-dependent ubiquitination.

Nat Cell Biol 2006 Dec 19;8(12):1415-23. Epub 2006 Nov 19.

Department of Experimental Medicine and Pathology, University La Sapienza, Roma, 324 Viale Regina Elena, 00161 Roma, Italy.

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http://dx.doi.org/10.1038/ncb1510DOI Listing
December 2006

Novel BRCA1 and BRCA2 germline mutations and assessment of mutation spectrum and prevalence in Italian breast and/or ovarian cancer families.

Breast Cancer Res Treat 2006 Nov 9;100(1):83-91. Epub 2006 May 9.

Department of Experimental Medicine and Pathology, University La Sapienza, Policlinico Umberto I Viale Regina Elena, 324, 00161 Rome, Italy.

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http://dx.doi.org/10.1007/s10549-006-9225-9DOI Listing
November 2006

Alternative TrkAIII splicing: a potential regulated tumor-promoting switch and therapeutic target in neuroblastoma.

Future Oncol 2005 Oct;1(5):689-98

University of L'Aquila, Department of Experimental Medicine, Via Vetoio, Coppito 2, 67100 L'Aquila, Italy.

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https://www.futuremedicine.com/doi/10.2217/14796694.1.5.689
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http://dx.doi.org/10.2217/14796694.1.5.689DOI Listing
October 2005

L-DOPA treatment of parkinsonian rats changes the expression of Src, Lyn and PKC kinases.

Neurosci Lett 2006 May 9;398(3):211-4. Epub 2006 Mar 9.

Dipartimento di Medicina Sperimentale e Patologia, Università La Sapienza, viale Regina Elena 324, 00161 Rome, Italy.

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http://dx.doi.org/10.1016/j.neulet.2005.12.077DOI Listing
May 2006

Cross talk among Notch3, pre-TCR, and Tal1 in T-cell development and leukemogenesis.

Blood 2006 Apr 20;107(8):3313-20. Epub 2005 Dec 20.

Dipartimento di Medicina Sperimentale e Patologia, University La Sapienza, Viale Regina Elena 32400161 Roma, Italy.

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http://dx.doi.org/10.1182/blood-2005-07-2823DOI Listing
April 2006

BRCA1 and BRCA2: the genetic testing and the current management options for mutation carriers.

Crit Rev Oncol Hematol 2006 Jan 6;57(1):1-23. Epub 2005 Dec 6.

Department of Experimental Medicine and Pathology, University La Sapienza, Policlinico Umberto I, Viale Regina Elena 324, 00161 Rome, Italy.

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http://dx.doi.org/10.1016/j.critrevonc.2005.05.003DOI Listing
January 2006

Hedgehog checkpoints in medulloblastoma: the chromosome 17p deletion paradigm.

Trends Mol Med 2005 Dec 14;11(12):537-45. Epub 2005 Nov 14.

Department of Experimental Medicine and Pathology, La Sapienza University, Viale Regina Elena 324, 00161 Rome, Italy.

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http://dx.doi.org/10.1016/j.molmed.2005.10.005DOI Listing
December 2005